All Stories

  1. In Vivo Function of the ER-Golgi Transport Protein LMAN1 in Photoreceptor Homeostasis

    Article • January 2014, Springer Science + Business Media

    Dr Bin Zhang

  2. Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII)

    Article • Journal of Biological Chemistry, May 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Bin Zhang

  3. SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion

    Article • eLife, April 2013, eLife

    Dr Bin Zhang

  4. Successful percutaneous coronary intervention in a patient with combined deficiency of FV and FVIII due to novel compound heterozygous mutations in LMAN1

    Article • Haemophilia, April 2013, Wiley

    Dr Bin Zhang

  5. A synonymous mutation in LMAN1 creates an ectopic splice donor site and causes combined deficiency of FV and FVIII

    Article • Journal of Thrombosis and Haemostasis, October 2012, Wiley

    Dr Bin Zhang

  6. Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of  1-antitrypsin

    Article • Blood, July 2011, American Society of Hematology

    Dr Bin Zhang

  7. Molecular basis of LMAN1 in coordinating LMAN1-MCFD2 cargo receptor formation and ER-to-Golgi transport of FV/FVIII

    Article • Blood, September 2010, American Society of Hematology

    Dr Bin Zhang

  8. EF-hand domains of MCFD2 mediate interactions with both LMAN1 and coagulation factor V or VIII

    Article • Blood, December 2009, American Society of Hematology

    Dr Bin Zhang

  9. Cargo Selectivity of the ERGIC-53/MCFD2 Transport Receptor Complex

    Article • Traffic, August 2006, Wiley

    Dr Bin Zhang

  10. Combined deficiency of factor V and factor VIII is due to mutations in either LMAN1 or MCFD2

    Article • Blood, March 2006, American Society of Hematology

    Dr Bin Zhang

  11. LMAN1 and MCFD2 Form a Cargo Receptor Complex and Interact with Coagulation Factor VIII in the Early Secretory Pathway

    Article • Journal of Biological Chemistry, May 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Bin Zhang

  12. LMAN1 is a molecular chaperone for the secretion of coagulation factor VIII1

    Article • Journal of Thrombosis and Haemostasis, November 2003, Wiley

    Dr Bin Zhang