All Stories

  1. Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity

    Article • Cell Metabolism, February 2019, Elsevier

    Dr Wenxian Fu

  2. PPARγ deacetylation dissociates thiazolidinedione’s metabolic benefits from its adverse effects

    Article • Journal of Clinical Investigation, May 2018, American Society for Clinical Investigation

    Dr Wenxian Fu

  3. Distinct gene signatures predict insulin resistance in young mice with high fat diet-induced obesity

    Article • Physiological Genomics, March 2018, American Physiological Society

    Dr Wenxian Fu

  4. CD122 blockade restores immunological tolerance in autoimmune type 1 diabetes via multiple mechanisms

    Article • JCI Insight, January 2018, American Society for Clinical Investigation

    Dr Wenxian Fu

  5. CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells

    Article • eLife, November 2017, eLife

    Dr Wenxian Fu

  6. Preventive Inhibition of Liver Tumorigenesis by Systemic Activation of Innate Immune Functions

    Article • Cell Reports, November 2017, Elsevier

    Dr Wenxian Fu

  7. Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity

    Article • Cell, October 2017, Elsevier

    Dr Wenxian Fu

  8. A Novel miR-24–TCF1 Axis in Modulating Effector T Cell Responses

    Article • The Journal of Immunology, April 2017, The American Association of Immunologists

    Dr Wenxian Fu

  9. Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells

    Article • eLife, November 2014, eLife

    Dr Wenxian Fu, Dr Rab K Prinjha

  10. Type 1 Diabetes in NOD Mice Unaffected by Mast Cell Deficiency

    Article • Diabetes, June 2014, American Diabetes Association

    Dr Wenxian Fu

  11. A Correction to the Research Article Titled: "Restoration of the Unfolded Protein Response in Pancreatic   Cells Protects Mice Against Type 1 Diabetes" by F. Engin, A. Yermalovich, T. Ngyuen, S. Hummasti, W. Fu, D. L. Eizirik, D. Mathis, G. S. Hotamisl...

    Article • Science Translational Medicine, December 2013, American Association for the Advancement of Science

    Dr Wenxian Fu

  12. Restoration of the Unfolded Protein Response in Pancreatic   Cells Protects Mice Against Type 1 Diabetes

    Article • Science Translational Medicine, November 2013, American Association for the Advancement of Science

    Dr Wenxian Fu

  13. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells

    Article • Nature Immunology, September 2012, Springer Science + Business Media

    Dr Wenxian Fu

  14. Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging

    Article • Nature Immunology, February 2012, Springer Science + Business Media

    Dr Wenxian Fu