All Stories

  1. Mechanism of Thiosulfate Oxidation in the SoxA Family of Cysteine-ligated Cytochromes
  2. Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS)
  3. Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility
  4. Structural biology of Tat protein transport
  5. Engineering of factor H binding protein, a key vaccine antigen for the prevention of meningococcal disease
  6. Building a secreting nanomachine: a structural overview of the T3SS
  7. Identification and characterization of the ‘missing’ terminal enzyme for siroheme biosynthesis in α‐proteobacteria
  8. Functional Analysis of the Interdependence between DNA Uptake Sequence and Its Cognate ComP Receptor during Natural Transformation inNeisseria Species
  9. Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands
  10. Investigating the structure of the factor B vWF-A domain/CD55 protein–protein complex using DEER spectroscopy: successes and pitfalls
  11. Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly
  12. Distinct Binding and Immunogenic Properties of the Gonococcal Homologue of Meningococcal Factor H Binding Protein
  13. Further structural insights into the binding of complement factor H by complement regulator-acquiring surface protein 1 (CspA) ofBorrelia burgdorferi
  14. ErpC, a member of the complement regulator-acquiring family of surface proteins fromBorrelia burgdorferi, possesses an architecture previously unseen in this protein family
  15. Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59
  16. Structures of CD200/CD200 Receptor Family and Implications for Topology, Regulation, and Evolution
  17. Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen
  18. Architecture of the major component of the type III secretion system export apparatus
  19. Structure of the TatC core of the twin-arginine protein transport system
  20. Semaphorin-7A Is an Erythrocyte Receptor for P. falciparum Merozoite-Specific TRAP Homolog, MTRAP
  21. Putting the structure into complement
  22. Specificity and mechanism of assembly of C4b binding protein
  23. The novel Jagged1/CD46 interaction: A prime target for immune modulation by viruses?
  24. Structural findings in complement factor H-related proteins unravel the pathogenesis of C3 glomerulopathy
  25. Identification of Jagged1 as a novel ligand for CD46: An interaction required for normal induction and regulation of human TH1 responses
  26. Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules
  27. The CD46-Jagged1 interaction is critical for human TH1 immunity
  28. Notch receptor–ligand binding and activation: Insights from molecular studies
  29. Chicken TAP genes are polymorphic and co-evolve with the dominantly-expressed class I gene
  30. Tetartohedral twinning could happen to you too
  31. Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9
  32. Factor I Autoantibodies in Patients with Atypical Hemolytic Uremic Syndrome: Disease-Associated or an Epiphenomenon?
  33. SAS-6 oligomerization: the key to the centriole?
  34. Complement factor I in health and disease
  35. Structures of the rat complement regulator CrrY
  36. Structure of Human Complement C8, a Precursor to Membrane Attack
  37. Shigella flexneri Spa15 Crystal Structure Verified in Solution by Double Electron Electron Resonance
  38. The vaccine antigen factor H binding protein from Neisseria meningitidis can be modified to reduce binding to factor H with no change in immunogenicity
  39. Binding characteristics and immunogenicity of modified factor H binding protein from Neisseria meningitidis
  40. Factor I autoantibodies are associated with atypical haemolytic uraemic syndrome
  41. EspM2 is a RhoA guanine nucleotide exchange factor
  42. With phases: how two wrongs can sometimes make a right
  43. Timing is everything: the regulation of type III secretion
  44. The interaction between factor H and Neisseria meningitidis
  45. Towards the crystal structure of intact Human Complement Factor I
  46. A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol
  47. Three-dimensional reconstruction of the Shigella T3SS transmembrane regions reveals 12-fold symmetry and novel features throughout
  48. Mutational analyses of the BbCRASP-1 protein of Borrelia burgdorferi identify residues relevant for the architecture and binding of host complement regulators FHL-1 and factor H
  49. Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates
  50. The Escherichia coli Cell Division Protein and Model Tat Substrate SufI (FtsP) Localizes to the Septal Ring and Has a Multicopper Oxidase-Like Structure
  51. Determining the structure of the complex between vWF-A of factor B and CD55
  52. The crystal structure of rat complement receptor 1-related protein Y (CrrY) helps dissecting decay-acceleration and fI-cofactor activities
  53. Single-particle electron microscopy reconstruction of the structure of complement component 8 (C8) at 23Å resolution
  54. A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition
  55. Structure of and influence of a tick complement inhibitor on human complement component 5
  56. Structures of the Shigella flexneri Type 3 Secretion System Protein MxiC Reveal Conformational Variability Amongst Homologues
  57. Complement Factor H: Using Atomic Resolution Structure to Illuminate Disease Mechanisms
  58. Interactions between factor H and Neisseria meningitidis
  59. Towards a structural basis for complement factor H linked age-related macular degeneration
  60. Structural analysis of the soluble C5b-9 complex using cryo-electron microscopy
  61. TatBC, TatB, and TatC form structurally autonomous units within the twin arginine protein transport system ofEscherichia coli
  62. High-resolution structures of bacterially expressed soluble human CD59
  63. The Structure of OMCI, a Novel Lipocalin Inhibitor of the Complement System
  64. Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6–8
  65. Surface plasmon resonance analysis of decay acceleration in the alternative pathway of complement
  66. Structural studies of human CD59 and its ligands
  67. Crystallographic studies of human complement factor I
  68. Structural insights into complement function via studies of pathogen derived proteins
  69. Modelling the complex between CD55 and Factor B using electron paramagnetic resonance
  70. Crystallographic studies of sugar binding by factor H domains 6–8
  71. Human complement factor I glycosylation: Structural and functional characterisation of the N-linked oligosaccharides
  72. Expression, limited proteolysis and preliminary crystallographic analysis of IpaD, a component of theShigella flexneritype III secretion system
  73. Expression, purification, crystallization and preliminary crystallographic analysis of BipD, a component of theBurkholderia pseudomalleitype III secretion system
  74. Structure–function mapping of BbCRASP-1, the key complement factor H and FHL-1 binding protein of Borrelia burgdorferi
  75. Expression, purification, crystallization and preliminary crystallographic analysis of MxiH, a subunit of theShigella flexneritype III secretion system needle
  76. The Characterization of Weak Protein–Protein Interactions: Evidence from DEER for the Trimerization of a von Willebrand Factor A Domain in Solution
  77. The type III needle and the damage done
  78. Helical Packing of Needles from Functionally Altered Shigella Type III Secretion Systems
  79. From Structure to Function of a Complement Regulator
  80. A novel fold for the factor H–binding protein BbCRASP-1 of Borrelia burgdorferi
  81. Biological activity, membrane-targeting modification, and crystallization of soluble human decay accelerating factor expressed inE. coli
  82. Crystallization and preliminary X-ray diffraction analysis of three EGF domains of EMR2, a 7TM immune-system molecule
  83. Crystallization and preliminary crystallographic analysis of BbCRASP-1, a complement regulator-acquiring surface protein ofBorrelia burgdorferi
  84. Characterizing sequence variation in the VP1 capsid proteins of foot and mouth disease virus (serotype 0) with respect to virion structure
  85. Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity
  86. Structural comparison of two strains of foot-and-mouth disease virus subtype O1 and a laboratory antigenic variant, G67
  87. Structure of a major immunogenic site on foot-and-mouth disease virus
  88. Crystallization and preliminary X-ray analysis of three serotypes of foot-and-mouth disease virus