All Stories

  1. Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly

    Article • PLoS Pathogens, May 2022, PLOS

    Dr Alexander N Freiberg

  2. SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Dr Alexander N Freiberg

  3. Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines

    Article • Journal of Neuroinflammation, November 2018, Springer Science + Business Media

    Dr Alexander N Freiberg

  4. Recent advances in the development of antiviral therapeutics for Rift Valley fever virus infection

    Article • Future Virology, October 2017, Future Medicine

    Dr Alexander N Freiberg

  5. Bolstering Components of the Immune Response Compromised by Prior Exposure to Adenovirus: Guided Formulation Development for a Nasal Ebola Vaccine

    Article • Molecular Pharmaceutics, August 2015, American Chemical Society (ACS)

    Dr Alexander N Freiberg

  6. Timing of Galectin-1 Exposure Differentially Modulates Nipah Virus Entry and Syncytium Formation in Endothelial Cells

    Article • Journal of Virology, December 2014, ASM Journals

    Dr Alexander N Freiberg

  7. Evidence for henipavirus spillover into human populations in Africa

    Article • Nature Communications, November 2014, Springer Science + Business Media

    Dr Alexander N Freiberg

  8. Efficient Reverse Genetics Reveals Genetic Determinants of Budding and Fusogenic Differences between Nipah and Hendra Viruses and Enables Real-Time Monitoring of Viral Spread in Small Animal Models of Henipavirus Infection

    Article • Journal of Virology, November 2014, ASM Journals

    Dr Alexander N Freiberg, Benhur Lee

  9. Multiplexed Digital mRNA Profiling of the Inflammatory Response in the West Nile Swiss Webster Mouse Model

    Article • PLoS Neglected Tropical Diseases, October 2014, PLOS

    Dr Alexander N Freiberg

  10. Bunyaviruses: Hantavirus and Others

    Article • January 2014, Springer Science + Business Media

    Dr Alexander N Freiberg

  11. Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever

    Article • PLoS Neglected Tropical Diseases, December 2013, PLOS

    Dr Alexander N Freiberg

  12. Modeling Pre-Existing Immunity to Adenovirus in Rodents: Immunological Requirements for Successful Development of a Recombinant Adenovirus Serotype 5-Based Ebola Vaccine

    Article • Molecular Pharmaceutics, September 2013, American Chemical Society (ACS)

    Dr Alexander N Freiberg

  13. Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes

    Article • Virus Research, August 2013, Elsevier

    Dr Alexander N Freiberg

  14. Rift Valley Fever Virus and Hemorrhagic Fever

    Article • June 2013, Taylor & Francis

    Dr Alexander N Freiberg

  15. Characterization of Rift Valley Fever Virus MP-12 Strain Encoding NSs of Punta Toro Virus or Sandfly Fever Sicilian Virus

    Article • PLoS Neglected Tropical Diseases, April 2013, PLOS

    Dr Alexander N Freiberg, Dr Tetsuro Ikegami

  16. Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol

    Article • Immunity, January 2013, Elsevier

    Dr Alexander N Freiberg

  17. Recent progress in henipavirus research: Molecular biology, genetic diversity, animal models

    Article • Antiviral Research, August 2012, Elsevier

    Dr Alexander N Freiberg

  18. Mutational analysis of positively charged amino acid residues of Uukuniemi phlebovirus nucleocapsid protein

    Article • Virus Research, July 2012, Elsevier

    Professor Alexander Plyusnin, Dr Alexander N Freiberg

  19. Chemotactic and Inflammatory Responses in the Liver and Brain Are Associated with Pathogenesis of Rift Valley Fever Virus Infection in the Mouse

    Article • PLoS Neglected Tropical Diseases, February 2012, PLOS

    Dr Alexander N Freiberg

  20. An Assembly Model of Rift Valley Fever Virus

    Article • Frontiers in Microbiology, January 2012, Frontiers

    Dr Alexander N Freiberg

  21. A Single Sublingual Dose of an Adenovirus-Based Vaccine Protects against Lethal Ebola Challenge in Mice and Guinea Pigs

    Article • Molecular Pharmaceutics, January 2012, American Chemical Society (ACS)

    Dr Alexander N Freiberg

  22. Differential cytokine responses from primary human Kupffer cells following infection with wild-type or vaccine strain yellow fever virus

    Article • Virology, March 2011, Elsevier

    Dr Alexander N Freiberg

  23. Ubiquitin-Regulated Nuclear-Cytoplasmic Trafficking of the Nipah Virus Matrix Protein Is Important for Viral Budding

    Article • PLoS Pathogens, November 2010, PLOS

    Dr Alexander N Freiberg

  24. Oligomerization of Uukuniemi virus nucleocapsid protein

    Article • Virology Journal, August 2010, Springer Science + Business Media

    Professor Alexander Plyusnin, Dr Alexander N Freiberg

  25. A replication-incompetent Rift Valley fever vaccine: Chimeric virus-like particles protect mice and rats against lethal challenge

    Article • Virology, February 2010, Elsevier

    Dr Alexander N Freiberg

  26. Identification of novel cellular targets for therapeutic intervention against Ebola virus infection by siRNA screening

    Article • Drug Development Research, June 2009, Wiley

    Dr Alexander N Freiberg

  27. Single-particle cryo-electron microscopy of Rift Valley fever virus

    Article • Virology, April 2009, Elsevier

    Dr Alexander N Freiberg

  28. Phage Tailspike Proteins withβ-Solenoid Fold as Thermostable Carbohydrate Binding Materials

    Article • Macromolecular Bioscience, February 2009, Wiley

    Dr Alexander N Freiberg

  29. A catalytically and genetically optimized β-lactamase-matrix based assay for sensitive, specific, and higher throughput analysis of native henipavirus entry characteristics

    Article • Virology Journal, January 2009, Springer Science + Business Media

    Dr Alexander N Freiberg

  30. Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus

    Article • PLoS Pathogens, August 2008, PLOS

    Dr Alexander N Freiberg

  31. An Intersubunit Active Site between Supercoiled Parallel β Helices in the Trimeric Tailspike Endorhamnosidase of Shigella flexneri Phage Sf6

    Article • Structure, May 2008, Elsevier

    Dr Alexander N Freiberg

  32. Establishment and characterization of plasmid-driven minigenome rescue systems for Nipah virus: RNA polymerase I- and T7-catalyzed generation of functional paramyxoviral RNA

    Article • Virology, January 2008, Elsevier

    Dr Alexander N Freiberg

  33. Folding and Stability of the Leucine-rich Repeat Domain of Internalin B from Listeria monocytogenes

    Article • Journal of Molecular Biology, March 2004, Elsevier

    Dr Alexander N Freiberg

  34. Stability and Folding of Internalin B - A Biophysical Characterization

    Article • September 2002, Elsevier

    Dr Alexander N Freiberg