All Stories

  1. The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus

    Article • PLoS Genetics, September 2019, PLOS

    Axel Brakhage, Professor Hubertus Haas

  2. β-1,3-glucan-lacking Aspergillus fumigatus mediates an efficient antifungal immune response by activating complement and dendritic cells

    Article • Virulence, October 2018, Taylor & Francis

    Dr Johannes Wagener, Lukas Huber, Professor Hubertus Haas, Professor Doris Wilflingseder, Axel Brakhage

  3. Exploiting the Concept of Multivalency with 68Ga- and 89Zr-Labelled Fusarinine C-Minigastrin Bioconjugates for Targeting CCK2R Expression

    Article • Contrast Media & Molecular Imaging, January 2018, Hindawi Publishing Corporation

    Professor Hubertus Haas, Dr Christine Rangger

  4. Comparative proteomics of a tor inducible Aspergillus fumigatus mutant reveals involvement of the Tor kinase in iron regulation

    Article • PROTEOMICS, May 2015, Wiley

    Professor Hubertus Haas, Olaf Kniemeyer

  5. Pseudomonas aeruginosa manipulates redox and iron homeostasis of its microbiota partner Aspergillus fumigatus via phenazines

    Article • Scientific Reports, February 2015, Springer Science + Business Media

    Professor Hubertus Haas

  6. [68Ga]FSC-(RGD)3 a trimeric RGD peptide for imaging αvβ3 integrin expression based on a novel siderophore derived chelating scaffold—synthesis and evaluation

    Article • Nuclear Medicine and Biology, February 2015, Elsevier

    Professor Hubertus Haas, Dr Christine Rangger

  7. An Iron-Mimicking, Trojan Horse-Entering Fungi—Has the Time Come for Molecular Imaging of Fungal Infections?

    Article • PLoS Pathogens, January 2015, PLOS

    Professor Hubertus Haas

  8. Deciphering the Combinatorial DNA-binding Code of the CCAAT-binding Complex and the Iron-regulatory Basic Region Leucine Zipper (bZIP) Transcription Factor HapX

    Article • Journal of Biological Chemistry, January 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Hubertus Haas

  9. ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence

    Article • PLoS Pathogens, November 2014, PLOS

    Professor Hubertus Haas, Dr Bridget Marie Barker

  10. Selected 68Ga-siderophores versus 68Ga-colloid and 68Ga-citrate: biodistribution and small animal imaging in mice

    Article • Biomedical Papers, October 2014, Palacky University Olomouc

    Professor Hubertus Haas

  11. Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus

    Article • Frontiers in Microbiology, October 2014, Frontiers

    Professor Hubertus Haas

  12. The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis

    Article • PLoS Pathogens, October 2014, PLOS

    Professor Hubertus Haas

  13. Hydroxamate Production as a High Affinity Iron Acquisition Mechanism in Paracoccidioides Spp

    Article • PLoS ONE, August 2014, PLOS

    Professor Hubertus Haas

  14. A novel multivalent bifunctional siderophore chelator scaffold for radiolabeling with gallium-68 based on fusarinine C

    Article • Nuclear Medicine and Biology, August 2014, Elsevier

    Professor Hubertus Haas, Dr Christine Rangger

  15. 89Zr labeling and preliminary evaluation of a trimeric RGD peptide based on a novel siderophore derived chelating scaffold

    Article • Nuclear Medicine and Biology, August 2014, Elsevier

    Professor Hubertus Haas, Dr Christine Rangger

  16. Genome mining and functional genomics for siderophore production in Aspergillus niger

    Article • Briefings in Functional Genomics, July 2014, Oxford University Press (OUP)

    Professor Hubertus Haas

  17. The novel globin protein fungoglobin is involved in low oxygen adaptation ofAspergillus fumigatus

    Article • Molecular Microbiology, July 2014, Wiley

    Professor Hubertus Haas, Olaf Kniemeyer

  18. Improved MALDI-TOF Microbial Mass Spectrometry Imaging by Application of a Dispersed Solid Matrix

    Article • Journal of the American Society for Mass Spectrometry, June 2014, American Chemical Society (ACS)

    Professor Hubertus Haas

  19. Cations (Zn, Fe)

    Article • April 2014, ASM Journals

    Professor Hubertus Haas

  20. Biotrophy‐specific downregulation of siderophore biosynthesis in C olletotrichum graminicola is required for modulation of immune responses of maize

    Article • Molecular Microbiology, March 2014, Wiley

    Professor Hubertus Haas

  21. Fungal siderophore metabolism with a focus on Aspergillus fumigatus

    Article • Natural Product Reports, January 2014, Royal Society of Chemistry

    Professor Hubertus Haas

  22. An endogenous promoter for conditional gene expression in Acremonium chrysogenum: The xylan and xylose inducible promoter xyl1P

    Article • Journal of Biotechnology, January 2014, Elsevier

    Professor Hubertus Haas

  23. The role of coproporphyrinogen III oxidase and ferrochelatase genes in heme biosynthesis and regulation in Aspergillus niger

    Article • Applied Microbiology and Biotechnology, October 2013, Springer Science + Business Media

    Professor Hubertus Haas

  24. Linear fusigen as the major hydroxamate siderophore of the ectomycorrhizal Basidiomycota Laccaria laccata and Laccaria bicolor

    Article • BioMetals, September 2013, Springer Science + Business Media

    Professor Hubertus Haas

  25. Aspergillus fumigatus SidJ Mediates Intracellular Siderophore Hydrolysis

    Article • Applied and Environmental Microbiology, September 2013, ASM Journals

    Professor Hubertus Haas

  26. Regulation of Sulphur Assimilation Is Essential for Virulence and Affects Iron Homeostasis of the Human-Pathogenic Mould Aspergillus fumigatus

    Article • PLoS Pathogens, August 2013, PLOS

    Professor Hubertus Haas, Dr Jorge Amich

  27. Bimodular Peptide Synthetase SidE Produces Fumarylalanine in the Human Pathogen Aspergillus fumigatus

    Article • Applied and Environmental Microbiology, August 2013, ASM Journals

    Professor Hubertus Haas

  28. Correction: Targeting Iron Acquisition Blocks Infection with the Fungal Pathogens Aspergillus fumigatus and Fusarium oxysporum

    Article • PLoS Pathogens, July 2013, PLOS

    Professor Hubertus Haas

  29. Targeting Iron Acquisition Blocks Infection with the Fungal Pathogens Aspergillus fumigatus and Fusarium oxysporum

    Article • PLoS Pathogens, July 2013, PLOS

    Professor Hubertus Haas

  30. 68Ga-Triacetylfusarinine C and 68Ga-Ferrioxamine E for Aspergillus Infection Imaging: Uptake Specificity in Various Microorganisms

    Article • Molecular Imaging and Biology, July 2013, Springer Science + Business Media

    Clemens Decristoforo, Professor Hubertus Haas

  31. Characterization of the Link between Ornithine, Arginine, Polyamine and Siderophore Metabolism in Aspergillus fumigatus

    Article • PLoS ONE, June 2013, PLOS

    Professor Hubertus Haas

  32. Fungal siderophore biosynthesis is partially localized in peroxisomes

    Article • Molecular Microbiology, April 2013, Wiley

    Professor Hubertus Haas

  33. Iron competition in fungus-plant interactions

    Article • Plant Signaling & Behavior, February 2013, Taylor & Francis

    Professor Hubertus Haas

  34. The first promoter for conditional gene expression in Acremonium chrysogenum: Iron starvation-inducible mir1P

    Article • Journal of Biotechnology, January 2013, Elsevier

    Professor Hubertus Haas

  35. Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging

    Article • European Journal of Nuclear Medicine and Molecular Imaging, April 2012, Springer Science + Business Media

    Clemens Decristoforo, Professor Hubertus Haas

  36. In vitro and in vivo evaluation of selected 68Ga-siderophores for infection imaging

    Article • Nuclear Medicine and Biology, April 2012, Elsevier

    Clemens Decristoforo, Professor Hubertus Haas

  37. The interplay between vacuolar and siderophore-mediated iron storage in Aspergillus fumigatus

    Article • Metallomics, January 2012, Oxford University Press (OUP)

    Professor Hubertus Haas

  38. Iron – A Key Nexus in the Virulence of Aspergillus fumigatus

    Article • Frontiers in Microbiology, January 2012, Frontiers

    Professor Hubertus Haas

  39. Regulatory interactions for iron homeostasis in Aspergillus fumigatus inferred by a Systems Biology approach

    Article • BMC Systems Biology, January 2012, Springer Science + Business Media

    Professor Hubertus Haas

  40. Coordination of hypoxia adaptation and iron homeostasis in human pathogenic fungi

    Article • Frontiers in Microbiology, January 2012, Frontiers

    Professor Hubertus Haas

  41. SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

    Article • PLoS Genetics, December 2011, PLOS

    Professor Hubertus Haas, Dr Sven D Willger, Dr Bridget Marie Barker

  42. Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus

    Article • Proceedings of the National Academy of Sciences, November 2011, Proceedings of the National Academy of Sciences

    Professor Hubertus Haas

  43. The metalloreductase FreB is involved in adaptation of Aspergillus fumigatus to iron starvation

    Article • Fungal Genetics and Biology, November 2011, Elsevier

    Professor Hubertus Haas

  44. The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus

    Article • Molecular Microbiology, August 2011, Wiley

    Professor Hubertus Haas

  45. Iron homeostasis—Achilles’ heel of Aspergillus fumigatus?

    Article • Current Opinion in Microbiology, August 2011, Elsevier

    Professor Hubertus Haas

  46. The small molecular mass antifungal protein of Penicillium chrysogenum - a mechanism of action oriented review

    Article • Journal of Basic Microbiology, July 2011, Wiley

    Professor Hubertus Haas, Professor Laszlo Csernoch

  47. SidL, an Aspergillus fumigatus Transacetylase Involved in Biosynthesis of the Siderophores Ferricrocin and Hydroxyferricrocin

    Article • Applied and Environmental Microbiology, May 2011, ASM Journals

    Professor Hubertus Haas

  48. Analysis of theAspergillus fumigatusProteome Reveals Metabolic Changes and the Activation of the Pseurotin A Biosynthesis Gene Cluster in Response to Hypoxia

    Article • Journal of Proteome Research, May 2011, American Chemical Society (ACS)

    Professor Hubertus Haas, Olaf Kniemeyer

  49. Among Developmental Regulators, StuA but Not BrlA Is Essential for Penicillin V Production inPenicillium chrysogenum

    Article • Applied and Environmental Microbiology, December 2010, ASM Journals

    Professor Hubertus Haas

  50. The crucial role of the Aspergillus fumigatus siderophore system in interaction with alveolar macrophages

    Article • Microbes and Infection, November 2010, Elsevier

    Professor Hubertus Haas

  51. HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus

    Article • PLoS Pathogens, September 2010, PLOS

    Professor Hubertus Haas

  52. Comparison of 68Ga-siderophores for imaging Aspergillus fumigatus infections with PET

    Article • Nuclear Medicine and Biology, August 2010, Elsevier

    Clemens Decristoforo, Professor Hubertus Haas

  53. Self-Protection against Gliotoxin—A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin

    Article • PLoS Pathogens, June 2010, PLOS

    Professor Hubertus Haas

  54. Exploring the concordance of Aspergillus fumigatus pathogenicity in mice and Toll -deficient flies

    Article • Medical Mycology, May 2010, Oxford University Press (OUP)

    Professor Hubertus Haas

  55. A Novel Motif in Fungal Class 1 Histone Deacetylases Is Essential for Growth and Development of Aspergillus

    Article • Molecular Biology of the Cell, November 2009, American Society for Cell Biology (ASCB)

    Professor Hubertus Haas

  56. The interplay between iron and zinc metabolism in Aspergillus fumigatus

    Article • Fungal Genetics and Biology, September 2009, Elsevier

    Professor Hubertus Haas

  57. Ferricrocin, a Siderophore Involved in Intra- and Transcellular Iron Distribution in Aspergillus fumigatus

    Article • Applied and Environmental Microbiology, April 2009, ASM Journals

    Professor Hubertus Haas

  58. Development-dependent scavenging of nucleic acids in the filamentous fungusAspergillus fumigatus

    Article • RNA Biology, April 2009, Taylor & Francis

    Professor Hubertus Haas

  59. Exploring the concordance of Aspergillus fumigatus pathogenicity in mice and Toll-deficient flies

    Article • Medical Mycology, January 2009, Oxford University Press (OUP)

    Professor Hubertus Haas

  60. Effects of the Aspergillus fumigatus siderophore systems on the regulation of macrophage immune effector pathways and iron homeostasis

    Article • Immunobiology, November 2008, Elsevier

    Professor Hubertus Haas

  61. Sub-Telomere Directed Gene Expression during Initiation of Invasive Aspergillosis

    Article • PLoS Pathogens, September 2008, PLOS

    Professor Hubertus Haas

  62. Siderophores in Fungal Physiology and Virulence

    Article • Annual Review of Phytopathology, September 2008, Annual Reviews

    Professor Hubertus Haas

  63. SreA-mediated iron regulation in Aspergillus fumigatus

    Article • Molecular Microbiology, August 2008, Wiley

    Professor Hubertus Haas

  64. SREA is involved in regulation of siderophore biosynthesis, utilization and uptake in Aspergillus nidulans

    Article • Molecular Microbiology, July 2008, Wiley

    Professor Hubertus Haas

  65. Small ncRNA transcriptome analysis from Aspergillus fumigatus suggests a novel mechanism for regulation of protein synthesis

    Article • Nucleic Acids Research, February 2008, Oxford University Press (OUP)

    Professor Hubertus Haas

  66. Potential Basis for Amphotericin B Resistance in Aspergillus terreus

    Article • Antimicrobial Agents and Chemotherapy, February 2008, ASM Journals

    Professor Hubertus Haas

  67. Functional and Physical Interaction of Blue- and Red-Light Sensors in Aspergillus nidulans

    Article • Current Biology, February 2008, Elsevier

    Professor Hubertus Haas

  68. EstB-Mediated Hydrolysis of the Siderophore Triacetylfusarinine C Optimizes Iron Uptake of Aspergillus fumigatus

    Article • Eukaryotic Cell, June 2007, ASM Journals

    Professor Hubertus Haas

  69. Interaction of HapX with the CCAAT-binding complex—a novel mechanism of gene regulation by iron

    Article • The EMBO Journal, June 2007, Wiley

    Professor Hubertus Haas, Olaf Kniemeyer

  70. Distinct Roles for Intra- and Extracellular Siderophores during Aspergillus fumigatus Infection

    Article • PLoS Pathogens, January 2007, PLOS

    Professor Hubertus Haas

  71. The Intracellular Siderophore Ferricrocin Is Involved in Iron Storage, Oxidative-Stress Resistance, Germination, and Sexual Development in Aspergillus nidulans

    Article • Eukaryotic Cell, October 2006, ASM Journals

    Professor Hubertus Haas

  72. NPS6, Encoding a Nonribosomal Peptide Synthetase Involved in Siderophore-Mediated Iron Metabolism, Is a Conserved Virulence Determinant of Plant Pathogenic Ascomycetes

    Article • The Plant Cell, October 2006, American Society of Plant Biologists (ASPB)

    Professor Hubertus Haas

  73. Corrigendum: Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

    Article • January 2006, Nature

    Professor Hubertus Haas

  74. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

    Article • December 2005, Nature

    Professor Hubertus Haas

  75. HdaA, a Major Class 2 Histone Deacetylase of Aspergillus nidulans, Affects Growth under Conditions of Oxidative Stress

    Article • Eukaryotic Cell, October 2005, ASM Journals

    Professor Hubertus Haas

  76. Penicillium chrysogenum glucose oxidase - a study on its antifungal effects

    Article • Journal of Applied Microbiology, December 2004, Wiley

    Professor Hubertus Haas

  77. Ferrichrome in Schizosaccharomyces pombe ? an iron transport and iron storage compound

    Article • BioMetals, November 2004, Springer Science + Business Media

    Professor Hubertus Haas

  78. Biosynthesis and Uptake of Siderophores Is Controlled by the PacC-Mediated Ambient-pH Regulatory System in Aspergillus nidulans

    Article • Eukaryotic Cell, April 2004, ASM Journals

    Professor Hubertus Haas

  79. 4?-Phosphopantetheinyl transferase-encoding npgA is essential for siderophore biosynthesis in Aspergillus nidulans

    Article • Current Genetics, December 2003, Springer Science + Business Media

    Professor Hubertus Haas

  80. Active Internalization of the Penicillium chrysogenum Antifungal Protein PAF in Sensitive Aspergilli

    Article • Antimicrobial Agents and Chemotherapy, October 2003, ASM Journals

    Professor Hubertus Haas

  81. Molecular genetics of fungal siderophore biosynthesis and uptake: the role of siderophores in iron uptake and storage

    Article • Applied Microbiology and Biotechnology, September 2003, Springer Science + Business Media

    Professor Hubertus Haas

  82. The siderophore system is essential for viability of Aspergillus nidulans: functional analysis of two genes encoding l-ornithine N 5-monooxygenase (sidA) and a non-ribosomal peptide synthetase (sidC)

    Article • Molecular Microbiology, June 2003, Wiley

    Professor Hubertus Haas

  83. Characterization of the Aspergillus nidulans transporters for the siderophores enterobactin and triacetylfusarinine C

    Article • Biochemical Journal, April 2003, Portland Press Ltd.

    Professor Hubertus Haas

  84. A Circadian Oscillator in Aspergillus spp. Regulates Daily Development and Gene Expression

    Article • Eukaryotic Cell, April 2003, ASM Journals

    Dr nancy p keller, Professor Hubertus Haas

  85. Regulation of freA, acoA, lysF, and cycA Expression by Iron Availability in Aspergillus nidulans

    Article • Applied and Environmental Microbiology, November 2002, ASM Journals

    Professor Hubertus Haas

  86. Identification of members of the Aspergillus nidulans SREA regulon: genes involved in siderophore biosynthesis and utilization

    Article • Biochemical Society Transactions, August 2002, Portland Press Ltd.

    Professor Hubertus Haas

  87. Comparative analysis of HD2 type histone deacetylases in higher plants

    Article • Planta, June 2001, Springer Science + Business Media

    Professor Hubertus Haas

  88. The Aspergillus nidulans GATA transcription factor gene areB encodes at least three proteins and features three classes of mutation

    Article • Molecular Microbiology, April 2001, Wiley

    Professor Hubertus Haas

  89. Iron starvation leads to increased expression of Cu/Zn-superoxide dismutase inAspergillus

    Article • FEBS Letters, November 2000, Wiley

    Professor Hubertus Haas

  90. xylP Promoter-Based Expression System and Its Use for Antisense Downregulation of the Penicillium chrysogenum Nitrogen Regulator NRE

    Article • Applied and Environmental Microbiology, November 2000, ASM Journals

    Professor Hubertus Haas

  91. ASD4, a New GATA Factor of Neurospora crassa , Displays Sequence-Specific DNA Binding and Functions in Ascus and Ascospore Development †

    Article • Biochemistry, September 2000, American Chemical Society (ACS)

    Professor Hubertus Haas

  92. Characterization of two putative histone deacetylase genes from Aspergillus nidulans

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, June 2000, Elsevier

    Professor Hubertus Haas

  93. Analysis of the histone acetyltransferase B complex of maize embryos

    Article • Nucleic Acids Research, November 1999, Oxford University Press (OUP)

    Professor Hubertus Haas

  94. The Aspergillus nidulans GATA Factor SREA Is Involved in Regulation of Siderophore Biosynthesis and Control of Iron Uptake

    Article • Journal of Biological Chemistry, February 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Hubertus Haas

  95. Overexpression of nreB, a New GATA Factor-encoding Gene of Penicillium chrysogenum, Leads to Repression of the Nitrate Assimilatory Gene Cluster

    Article • Journal of Biological Chemistry, September 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Hubertus Haas

  96. Identification of Maize Histone Deacetylase HD2 as an Acidic Nucleolar Phosphoprotein

    Article • Science, July 1997, American Association for the Advancement of Science

    Professor Hubertus Haas

  97. Molecular analysis of a Penicillium chrysogenum GATA factor encoding gene (sreP) exhibiting significant homology to the Ustilago maydis urbs1 gene

    Article • Gene, January 1997, Elsevier

    Professor Hubertus Haas

  98. Sequence analysis and expression of thePenicillium chrysogenum nitrate reductase encoding gene (niaD)

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, November 1996, Elsevier

    Professor Hubertus Haas

  99. Cloning, structural organization and regulation of expression of the Penicillium chrysogenum paf gene encoding an abundantly secreted protein with antifungal activity

    Article • Gene, December 1995, Elsevier

    Professor Hubertus Haas

  100. Sequence and structure of Penicillium chrysogenum phoG, homologous to an acid phosphatase-encoding gene of Aspergillus nidulans

    Article • Gene, July 1995, Elsevier

    Professor Hubertus Haas

  101. NRE, the major nitrogen regulatory protein of Penicillium chrysogenum, binds specifically to elements in the intergenic promoter regions of nitrate assimilation and penicillin biosynthetic gene clusters

    Article • Current Genetics, July 1995, Springer Science + Business Media

    Professor Hubertus Haas

  102. Molecular cloning and analysis of nre, the major nitrogen regulatory gene of Penicillium chrysogenum

    Article • Current Genetics, January 1995, Springer Science + Business Media

    Professor Hubertus Haas

  103. Cloning and structural organization of a xylanase-encoding gene from Penicillium chrysogenum

    Article • Gene, April 1993, Elsevier

    Professor Hubertus Haas

  104. Purification, characterization and partial amino acid sequences of a xylanase produced by Penicillium chrysogenum

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, October 1992, Elsevier

    Professor Hubertus Haas

  105. Isolation and analysis of the Penicillium chrysogenum phoA gene encoding a secreted phosphate-repressible acid phosphatase

    Article • Gene, April 1992, Elsevier

    Professor Hubertus Haas

  106. Penicillium chrysogenum extracellular acid phosphatase: purification and biochemical characterization

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, August 1991, Elsevier

    Professor Hubertus Haas