All Stories

  1. Synthetic utility of endocyclic cleavage reaction

    Article • Pure and Applied Chemistry, July 2017, De Gruyter

    Dr Shino Manabe

  2. Antitumor effect of antitissue factor antibody‐MMAE conjugate in human pancreatic tumor xenografts

    Article • International Journal of Cancer, March 2015, Wiley

    Dr Shino Manabe

  3. Synthesis of 1,2-cis Amino Glycoside

    Article • October 2014, Springer Science + Business Media

    Dr Shino Manabe

  4. C-Mannosylation: Modification on Tryptophan in Cellular Proteins

    Article • October 2014, Springer Science + Business Media

    Dr Shino Manabe

  5. ChemInform Abstract: Pyranosides with 2,3-trans Carbamate Groups: Exocyclic or Endocyclic Cleavage Reaction?

    Article • ChemInform, August 2014, Wiley

    Dr Shino Manabe

  6. Pyranosides with 2,3-transCarbamate Groups: Exocyclic or Endocyclic Cleavage Reaction?

    Article • The Chemical Record, June 2014, Wiley

    Dr Shino Manabe

  7. ChemInform Abstract: Hafnium(IV) Tetratriflate in Selective Reductive Carbohydrate Benzylidene Acetal Opening Reaction and Direct Silylation Reaction.

    Article • ChemInform, April 2014, Wiley

    Dr Shino Manabe

  8. Synthesis of 1,2-cis Aminoglycoside

    Article • January 2014, Springer Science + Business Media

    Dr Shino Manabe

  9. C-Mannosylation: A Modification on Tryptophan in Cellular Proteins

    Article • January 2014, Springer Science + Business Media

    Dr Shino Manabe

  10. ChemInform Abstract: Sulfonylcarbamate as a Versatile and Unique Hydroxy-Protecting Group: A Protecting Group Stable under Severe Conditions and Labile under Mild Conditions.

    Article • ChemInform, December 2013, Wiley

    Dr Shino Manabe

  11. Significant Substituent Effect on the Anomerization of Pyranosides: Mechanism of Anomerization and Synthesis of a 1,2-cisGlucosamine Oligomer from the 1,2-transAnomer

    Article • Chemistry - A European Journal, December 2013, Wiley

    Dr Shino Manabe

  12. Hafnium(IV) tetratriflate in selective reductive carbohydrate benzylidene acetal opening reaction and direct silylation reaction

    Article • Tetrahedron Letters, December 2013, Elsevier

    Dr Shino Manabe

  13. Discovery of an uncovered region in fibrin clots and its clinical significance

    Article • Scientific Reports, September 2013, Springer Science + Business Media

    Dr Shino Manabe

  14. ChemInform Abstract: Design of Chemical Glycosyl Donors: Does Changing Ring Conformation Influence Selectivity/Reactivity?

    Article • ChemInform, July 2013, Wiley

    Dr Shino Manabe

  15. Hafnium(IV) Tetratriflate as a Glycosyl Fluoride Activation Reagent

    Article • The Journal of Organic Chemistry, May 2013, American Chemical Society (ACS)

    Dr Shino Manabe

  16. Design of chemical glycosyl donors: does changing ring conformation influence selectivity/reactivity?

    Article • Chemical Society Reviews, January 2013, Royal Society of Chemistry

    Dr Shino Manabe

  17. Development of a diketopiperazine-forming dipeptidyl Gly-Pro spacer for preparation of an antibody–drug conjugate

    Article • MedChemComm, January 2013, Royal Society of Chemistry

    Dr Shino Manabe

  18. Sulfonylcarbamate as a versatile and unique hydroxy-protecting group: a protecting group stable under severe conditions and labile under mild conditions

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Dr Shino Manabe

  19. Tumor stromal barrier and cancer stromal targeting therapy

    Article • Microvascular Reviews and Communications, January 2013, Japanese Society for Microcirculation

    Dr Shino Manabe

  20. Cancer Stromal Targeting

    Article • Drug Delivery System, January 2013, Japan Society of Drug Delivery System

    Dr Shino Manabe

  21. Cancer Stromal Targeting (CAST) Therapy and Tailored Antibody Drug Conjugate Therapy Depending on the Nature of Tumor Stroma

    Article • January 2013, Springer Science + Business Media

    Dr Shino Manabe

  22. Linker Technology in Antibody-Drug Conjugates for Cancer Treatment

    Article • Drug Delivery System, January 2013, Japan Society of Drug Delivery System

    Dr Shino Manabe

  23. 2,3-transカーバメート基を持つ糖構造の特異な反応性：糖化学におけるエンド開裂反応の再発見

    Article • Journal of Synthetic Organic Chemistry Japan, January 2013, The Society of Synthetic Organic Chemistry, Japan

    Dr Shino Manabe

  24. Tailored immunoconjugate therapy depending on a quantity of tumor stroma

    Article • Cancer Science, December 2012, Wiley

    Dr Shino Manabe

  25. Electrochemical generation of 2,3-oxazolidinone glycosyl triflates as an intermediate for stereoselective glycosylation

    Article • Beilstein Journal of Organic Chemistry, March 2012, Beilstein Institut

    Dr Shino Manabe

  26. 免疫アジュバントQS-21A の合成と作用機序解明へのアプローチ

    Article • Trends in Glycoscience and Glycotechnology, January 2012, Forum: Carbohydrates Coming of Age

    Dr Shino Manabe

  27. ChemInform Abstract: Radical C-Glycosylation Reaction of Pyranosides with the 2,3-trans Carbamate Group.

    Article • ChemInform, December 2011, Wiley

    Dr Shino Manabe

  28. Substituent effects in endocyclic cleavage–recyclization anomerization reaction of pyranosides

    Article • Tetrahedron, December 2011, Elsevier

    Dr Shino Manabe

  29. Cancer-Stroma Targeting Therapy by Cytotoxic Immunoconjugate Bound to the Collagen 4 Network in the Tumor Tissue

    Article • Bioconjugate Chemistry, September 2011, American Chemical Society (ACS)

    Dr Shino Manabe

  30. New concept of cytotoxic immunoconjugate therapy targeting cancer-induced fibrin clots

    Article • Cancer Science, May 2011, Wiley

    Dr Shino Manabe

  31. ChemInform Abstract: The Synthesis of 1,2-Cis-amino Containing Oligosaccharides Toward Biological Investigation

    Article • ChemInform, May 2011, Wiley

    Dr Shino Manabe

  32. Endocyclic Cleavage in Glycosides with 2,3- trans Cyclic Protecting Groups

    Article • Journal of the American Chemical Society, April 2011, American Chemical Society (ACS)

    Dr Shino Manabe

  33. Glycosyl Sulfonium Ions as Storable Intermediates for Glycosylations

    Article • Organic Letters, March 2011, American Chemical Society (ACS)

    Dr Shino Manabe

  34. Radical C-glycosylation reaction of pyranosides with the 2,3-trans carbamate group

    Article • Chemical Communications, January 2011, Royal Society of Chemistry

    Dr Shino Manabe

  35. N-Benzyl-2,3-trans-Carbamate-Bearing Glycosyl Donors for 1,2-cis-Selective Glycosylation Reactions

    Article • European Journal of Organic Chemistry, December 2010, Wiley

    Dr Shino Manabe

  36. ChemInform Abstract: Solid-Phase Oligosaccharide Synthesis and Related Technologies

    Article • ChemInform, June 2010, Wiley

    Dr Shino Manabe

  37. ChemInform Abstract: Total Synthesis of Novel Subclass of Glyco-amino Acid Structure Motif: C2-α-L-C-Mannosylpyranosyl-L-tryptophan.

    Article • ChemInform, June 2010, Wiley

    Dr Shino Manabe

  38. Theoretical Investigation of Solvent Effects on Glycosylation Reactions: Stereoselectivity Controlled by Preferential Conformations of the Intermediate Oxacarbenium-Counterion Complex

    Article • Journal of Chemical Theory and Computation, June 2010, American Chemical Society (ACS)

    Dr Shino Manabe

  39. ChemInform Abstract: Development of Novel Methodology for Rapid Conjugated Oligosaccharide Synthesis

    Article • ChemInform, May 2010, Wiley

    Dr Shino Manabe

  40. ChemInform Abstract: Tag-Reporter and Resin Capture-Release Strategy in Oligosaccharide Synthesis

    Article • ChemInform, May 2010, Wiley

    Dr Shino Manabe

  41. ChemInform Abstract: Optimizing Glycosylation Reaction Selectivities by Protecting Group Manipulation

    Article • ChemInform, March 2010, Wiley

    Dr Shino Manabe

  42. The Synthesis of 1,2-cis-Amino Containing Oligosaccharides Toward Biological Investigation

    Article • January 2010, Elsevier

    Dr Shino Manabe

  43. ChemInform Abstract: Significant Solvent Effect in Anomerization Reaction of Pyranosides with 2,3-trans Carbamate and Carbonate.

    Article • ChemInform, December 2009, Wiley

    Dr Shino Manabe

  44. ChemInform Abstract: Evidence for Endocyclic Cleavage of Conformationally Restricted Glycopyranosides.

    Article • ChemInform, December 2009, Wiley

    Dr Shino Manabe

  45. ChemInform Abstract: Development of Novel Glycosyl Donors for 1,2-cis Glycosylation Reaction for Amino Sugar and Synthesis of anti-Helicobacter pylori Oligosaccharide

    Article • ChemInform, September 2009, Wiley

    Dr Shino Manabe

  46. Significant solvent effect in anomerization reaction of pyranosides with 2,3-trans carbamate and carbonate

    Article • Tetrahedron Letters, August 2009, Elsevier

    Dr Shino Manabe

  47. Evidence for Endocyclic Cleavage of Conformationally Restricted Glycopyranosides

    Article • Chemistry - A European Journal, July 2009, Wiley

    Dr Shino Manabe

  48. Low-Barrier Pathway forendo-Cleavage Induced Anomerization of Pyranosides withN-Benzyl-2,3-trans-oxazolidinone Groups

    Article • European Journal of Organic Chemistry, March 2009, Wiley

    Dr Shino Manabe

  49. α- and β-Glycosyl Sulfonium Ions: Generation and Reactivity

    Article • Chemistry - A European Journal, February 2009, Wiley

    Dr Shino Manabe

  50. ChemInform Abstract: Reductive Deprotection of Propargyl Ether by a SmI2-Amine-Water System and Its Application to Polymer-Supported Oligosaccharide Synthesis.

    Article • ChemInform, December 2008, Wiley

    Dr Shino Manabe

  51. Optimizing Glycosylation Reaction Selectivities by Protecting Group Manipulation

    Article • Current Bioactive Compounds, December 2008, Bentham Science Publishers

    Dr Shino Manabe

  52. Phenyl 2-amino-N,6-O-dibenzyl-2,3-N,O-carbonyl-2-deoxy-1-thio-β-D-glucopyranoside

    Article • Acta Crystallographica Section E Structure Reports Online, September 2008, International Union of Crystallography

    Dr Shino Manabe

  53. Reductive deprotection of propargyl ether by a SmI2–amine–water system and its application to polymer-supported oligosaccharide synthesis

    Article • Tetrahedron Letters, August 2008, Elsevier

    Dr Shino Manabe

  54. The First Synthesis of N -Man-Trp: Alternative Mannosylation Modification of Protein

    Article • Synlett, April 2008, Thieme Publishing Group

    Dr Shino Manabe

  55. Development of Novel Glycosyl Donors for 1,2-cis Glycosylation Reaction for Amino Sugar and Synthesis of anti-Helicobacter pylori Oligosaccharide

    Article • Trends in Glycoscience and Glycotechnology, January 2008, Forum: Carbohydrates Coming of Age

    Dr Shino Manabe

  56. Synthesis of a Natural Oligosaccharide Antibiotic Active Against Helicobacter pylori.

    Article • ChemInform, October 2007, Wiley

    Dr Shino Manabe

  57. Synthesis of a Natural Oligosaccharide Antibiotic Active against Helicobacter pylori

    Article • The Journal of Organic Chemistry, August 2007, American Chemical Society (ACS)

    Dr Shino Manabe

  58. S-Phenyl 4,6-O-benzylidene-2,3-O-carbonyl-1-thia-α-D-mannopyranoside

    Article • Acta Crystallographica Section E Structure Reports Online, May 2007, International Union of Crystallography

    Dr Shino Manabe

  59. Facile Peptide Thioester Synthesis via Solution-Phase Tosylamide Preparation.

    Article • ChemInform, May 2007, Wiley

    Dr Shino Manabe

  60. Facile Preparation of N-Acylsulfonamides by Using Sulfonyl Isocyanate.

    Article • ChemInform, April 2007, Wiley

    Dr Shino Manabe

  61. Polymer-supported oligosaccharide synthesis using ultrafiltration methodology

    Article • Chemical Communications, January 2007, Royal Society of Chemistry

    Dr Shino Manabe

  62. Facile peptide thioester synthesis via solution-phase tosylamide preparation

    Article • Tetrahedron Letters, January 2007, Elsevier

    Dr Shino Manabe

  63. Facile preparation of N-acylsulfonamides by using sulfonyl isocyanate

    Article • Tetrahedron Letters, January 2007, Elsevier

    Dr Shino Manabe

  64. Systematic Synthesis of Bisubstrate-Type Inhibitors ofN-Acetylglucosaminyltransferases

    Article • Chemistry - A European Journal, April 2006, Wiley

    Dr Shino Manabe

  65. Divergent Synthesis of Sialylated Glycan Chains: Combined Use of Polymer Support, Resin Capture-Release, and Chemoenzymatic Strategies

    Article • Angewandte Chemie International Edition, July 2005, Wiley

    Dr Shino Manabe

  66. Divergent Synthesis of Sialylated Glycan Chains: Combined Use of Polymer Support, Resin Capture-Release, and Chemoenzymatic Strategies

    Article • Angewandte Chemie, July 2005, Wiley

    Dr Shino Manabe

  67. Synthesis of a Bisubstrate-Type Inhibitor ofN-Acetylglucosaminyltransferases

    Article • Angewandte Chemie, October 2004, Wiley

    Dr Shino Manabe

  68. Synthesis of a Bisubstrate-Type Inhibitor ofN-Acetylglucosaminyltransferases

    Article • Angewandte Chemie International Edition, October 2004, Wiley

    Dr Shino Manabe

  69. The Novel Glycoprotein Structure: C-Mannosyl Tryptophan

    Article • ChemInform, July 2004, Wiley

    Dr Shino Manabe

  70. Total Synthesis of Mannosyl Tryptophan and Its Derivatives

    Article • Chemistry - A European Journal, March 2003, Wiley

    Dr Shino Manabe

  71. Synthesis of Monoglucosylated High-Mannose-Type Dodecasaccharide, a Putative Ligand for Molecular Chaperone, Calnexin, and Calreticurin

    Article • Journal of the American Chemical Society, March 2003, American Chemical Society (ACS)

    Dr Shino Manabe

  72. Synthesis and Enediyne Antibiotic Oligosaccharides

    Article • ChemInform, February 2003, Wiley

    Dr Shino Manabe

  73. Polymer - Resin HybridCapture - Release Strategy for Rapid Oligo­saccharideConstruction

    Article • Synlett, January 2003, Thieme Publishing Group

    Dr Shino Manabe

  74. タンパク質修飾の新しい形；Ｃ‐結合型糖ペプチド

    Article • Trends in Glycoscience and Glycotechnology, January 2003, Forum: Carbohydrates Coming of Age

    Dr Shino Manabe

  75. On-Resin Real-Time Reaction Monitoring of Solid-Phase Oligosaccharide Synthesis

    Article • Journal of the American Chemical Society, October 2002, American Chemical Society (ACS)

    Dr Shino Manabe

  76. Tag-Reporter and Resin Capture–Release Strategy in Oligosaccharide Synthesis

    Article • Chemistry - A European Journal, July 2002, Wiley

    Dr Shino Manabe

  77. THE NOVEL METHODOLOGY FOR RAPID OLIGOSACCHARIDE SYNTHESIS

    Article • April 2002, Hindawi Publishing Corporation

    Dr Shino Manabe

  78. Preparation of Glycosylated Amino Acid Derivatives for Glycoprotein Synthesis by In Vitro Translation System

    Article • Bioorganic & Medicinal Chemistry, March 2002, Elsevier

    Dr Shino Manabe

  79. Development of Novel Methodology for Rapid Conjugated Oligosaccharide Synthesis.

    Article • YAKUGAKU ZASSHI, January 2002, Pharmaceutical Society of Japan

    Dr Shino Manabe

  80. Solid-Phase Capture-Release Strategy Applied to Oligosaccharide Synthesis on a Soluble Polymer Support

    Article • Angewandte Chemie International Edition, December 2001, Wiley

    Dr Shino Manabe

  81. Solid-Phase Capture-Release Strategy Applied to Oligosaccharide Synthesis on a Soluble Polymer Support

    Article • Angewandte Chemie, December 2001, Wiley

    Dr Shino Manabe

  82. Tag-Reporter Strategy for Facile Oligosaccharide Synthesis on Polymer Support

    Article • Journal of the American Chemical Society, April 2001, American Chemical Society (ACS)

    Dr Shino Manabe

  83. Synthesis of Enediyne Antibiotic Oligosaccharides

    Article • January 2001, Springer Science + Business Media

    Dr Shino Manabe

  84. Wang Resin-Type Linker Containing a Nitro Group for Polymer Support Oligosaccharide Synthesis: Polymer-Supported Glycosyl Donor.

    Article • Chemical and Pharmaceutical Bulletin, January 2001, Pharmaceutical Society of Japan

    Dr Shino Manabe

  85. Total Synthesis of Novel Subclass of Glyco-amino Acid Structure Motif; C 2 -α- d - C -Mannosyl- l -Tryptophan [ J. Am. Chem. Soc. 1999 , 121 , 9754−9755].

    Article • Journal of the American Chemical Society, May 2000, American Chemical Society (ACS)

    Dr Shino Manabe

  86. Total Synthesis of Novel Subclass of Glyco-amino Acid Structure Motif:  C 2 -α- l - C -Mannosylpyranosyl- l -tryptophan

    Article • Journal of the American Chemical Society, October 1999, American Chemical Society (ACS)

    Dr Shino Manabe

  87. Solvent Effect in Glycosylation Reaction on Polymer Support

    Article • Synlett, June 1998, Thieme Publishing Group

    Dr Shino Manabe

  88. Structural requirements of a chiral ligand for the catalytic asymmetric addition of thiophenol to α,β-unsaturated esters

    Article • Tetrahedron Letters, April 1998, Elsevier

    Dr Shino Manabe

  89. Multi-Component Carbohydrate Coupling using Solution and Polymer Support Technology

    Article • Molecules Online, January 1998, Springer Science + Business Media

    Dr Shino Manabe

  90. Enantioselective (2,3) Sigmatropic Rearrangement of .ALPHA.-Propargyloxyacetic Acids Mediated by BuLi-(-)-Sparteine Complex.

    Article • Chemical and Pharmaceutical Bulletin, January 1998, Pharmaceutical Society of Japan

    Dr Shino Manabe

  91. Solid-phase oligosaccharide synthesis and related technologies

    Article • Current Opinion in Chemical Biology, January 1998, Elsevier

    Dr Shino Manabe

  92. Toward Synthesis of Novel C-glycoprotein from Human RNase; Unexpected Stereochemistry of Epoxide Opening Reaction by Organolithium Reagents in the Presence of Lewis Acid.

    Article • Chemistry Letters, January 1998, Chemical Society of Japan

    Dr Shino Manabe

  93. 高分子科学最近の進歩 糖鎖の固相合成 糖鎖合成の迅速化を目指して

    Article • Kobunshi, January 1998, Society of Polymer Science, Japan

    Dr Shino Manabe

  94. Aza-[2,3] Sigmatropic Rearrangement of Phosphoramides

    Article • Tetrahedron Letters, April 1997, Elsevier

    Dr Shino Manabe

  95. Enantioselective [2,3] sigmatropic rearrangement mediated by a butyllithium–chiral ligand complex

    Article • Chemical Communications, January 1997, Royal Society of Chemistry

    Dr Shino Manabe

  96. The Total Synthesis of a Natural Cardenolide:  (+)-Digitoxigenin

    Article • Journal of the American Chemical Society, January 1996, American Chemical Society (ACS)

    Dr Shino Manabe, Frederick West