All Stories

  1. Association Between Genetic Polymorphisms and Pain Sensitivity in Patients with Hip Osteoarthritis

    Article • Pain Practice, November 2017, Wiley

    PhD Lona Louring Christrup

  2. Symptoms and side effects in chronic non-cancer pain patients: clinical implications and development of new assessment tools

    Article • Acta Anaesthesiologica Scandinavica, May 2015, Wiley

    PhD Lona Louring Christrup

  3. Objective markers of the analgesic response to morphine in experimental pain research

    Article • Journal of Pharmacological and Toxicological Methods, May 2015, Elsevier

    PhD Lona Louring Christrup

  4. A cortical source localization analysis of resting EEG data after remifentanil infusion

    Article • Clinical Neurophysiology, May 2015, Elsevier

    PhD Lona Louring Christrup

  5. Population pharmacokinetics of morphine and morphine-6-glucuronide following rectal administration – A dose escalation study

    Article • European Journal of Pharmaceutical Sciences, February 2015, Elsevier

    PhD Lona Louring Christrup

  6. Modelling concentration–analgesia relationships for morphine to evaluate experimental pain models

    Article • European Journal of Pharmaceutical Sciences, January 2015, Elsevier

    PhD Lona Louring Christrup

  7. Disruption of Cortical Connectivity during Remifentanil Administration Is Associated with Cognitive Impairment but Not with Analgesia

    Article • Anesthesiology, January 2015, Wolters Kluwer Health

    PhD Lona Louring Christrup

  8. Does mutual compensation of the cognitive effects induced by pain and opioids exist? An experimental study

    Article • Psychopharmacology, October 2014, Springer Science + Business Media

    PhD Lona Louring Christrup

  9. Altered Frequency Distribution in the Electroencephalogram is Correlated to the Analgesic Effect of Remifentanil

    Article • Basic & Clinical Pharmacology & Toxicology, October 2014, Wiley

    PhD Lona Louring Christrup

  10. Association Between Human Pain-Related Genotypes and Variability in Opioid Analgesia: An Updated Review

    Article • Pain Practice, September 2014, Wiley

    PhD Lona Louring Christrup

  11. Altered cortical causality after remifentanil administration in healthy volunteers: A novel approach for pharmaco-EEG

    Article • August 2014, Institute of Electrical & Electronics Engineers (IEEE)

    PhD Lona Louring Christrup

  12. Genetic, pathological and physiological determinants of transdermal fentanyl pharmacokinetics in 620 cancer patients of the EPOS study

    Article • Pharmacogenetics and Genomics, April 2014, Wolters Kluwer Health

    PhD Lona Louring Christrup

  13. Pharmacodynamic Modelling of Placebo and Buprenorphine Effects on Event-Related Potentials in Experimental Pain

    Article • Basic & Clinical Pharmacology & Toxicology, March 2014, Wiley

    PhD Lona Louring Christrup

  14. Pharmacokinetic-Pharmacodynamic Modelling of the Analgesic and Antihyperalgesic Effects of Morphine after Intravenous Infusion in Human Volunteers

    Article • Basic & Clinical Pharmacology & Toxicology, March 2014, Wiley

    PhD Lona Louring Christrup

  15. Barriers to Cancer Pain Management in Danish and Lithuanian Patients Treated in Pain and Palliative Care Units

    Article • Pain Management Nursing, March 2014, Elsevier

    PhD Lona Louring Christrup

  16. Quality of life and symptoms in patients with malignant diseases admitted to a comprehensive cancer centre

    Article • Supportive Care in Cancer, February 2014, Springer Science + Business Media

    PhD Lona Louring Christrup

  17. Exploratory survey study of long-term users of nicotine replacement therapy in Danish consumers

    Article • Harm Reduction Journal, January 2014, Springer Science + Business Media

    PhD Lona Louring Christrup

  18. Erratum to: A physiologically-based recirculatory meta-model for nasal fentanyl in man

    Article • Journal of Pharmacokinetics and Pharmacodynamics, January 2013, Springer Science + Business Media

    PhD Lona Louring Christrup

  19. Morphine- and buprenorphine-induced analgesia and antihyperalgesia in a human inflammatory pain model: a double-blind, randomized, placebo-controlled, five-arm crossover study

    Article • Journal of Pain Research, January 2013, Taylor & Francis

    PhD Lona Louring Christrup

  20. Differences between opioids: pharmacological, experimental, clinical and economical perspectives

    Article • British Journal of Clinical Pharmacology, December 2012, Wiley

    PhD Lona Louring Christrup

  21. A physiologically-based recirculatory meta-model for nasal fentanyl in man

    Article • Journal of Pharmacokinetics and Pharmacodynamics, August 2012, Springer Science + Business Media

    PhD Lona Louring Christrup

  22. Prediction of pain sensitivity in healthy volunteers

    Article • Journal of Pain Research, August 2012, Taylor & Francis

    PhD Lona Louring Christrup

  23. Pharmacokinetic/Pharmacodynamic Relationships of Transdermal Buprenorphine and Fentanyl in Experimental Human Pain Models

    Article • Basic & Clinical Pharmacology & Toxicology, December 2010, Wiley

    PhD Lona Louring Christrup

  24. A Pharmacokinetic and Pharmacodynamic Study of Oral Oxycodone in a Human Experimental Pain Model of Hyperalgesia

    Article • Clinical Pharmacokinetics, December 2010, Springer Science + Business Media

    PhD Lona Louring Christrup

  25. Psychological and behavioural predictors of pain management outcomes in patients with cancer

    Article • Scandinavian Journal of Caring Sciences, November 2010, Wiley

    PhD Lona Louring Christrup

  26. Rationales behind the choice of administration form with fentanyl: Delphi survey among Danish general practitioners

    Article • Journal of Opioid Management, July 2010, Weston Medical Publishing

    PhD Lona Louring Christrup

  27. The impact of an electronic monitoring and reminder device on patient compliance with antihypertensive therapy: a randomized controlled trial

    Article • Journal of Hypertension, January 2010, Wolters Kluwer Health

    PhD Lona Louring Christrup

  28. Danish Pain Specialists' Rationales behind the Choice of Fentanyl Transdermal Patches and Oral Transmucosal Systems—A Delphi Study

    Article • Pain Medicine, November 2009, Oxford University Press (OUP)

    PhD Lona Louring Christrup

  29. Survey of patient and physician assessment of a compliance reminder device in the treatment of hypertension

    Article • Blood Pressure, October 2009, Taylor & Francis

    PhD Lona Louring Christrup

  30. Novel formulations and routes of administration for opioids in the treatment of breakthrough pain

    Article • Therapy, September 2009, Future Medicine

    PhD Lona Louring Christrup

  31. The Danish Barriers Questionnaire-II: Preliminary Validation in Cancer Pain Patients

    Article • Pain Practice, July 2009, Wiley

    PhD Lona Louring Christrup

  32. Patient-related barriers to cancer pain management: a systematic exploratory review

    Article • Scandinavian Journal of Caring Sciences, March 2009, Wiley

    PhD Lona Louring Christrup

  33. Survey of patient and physician assessment of a compliance reminder device in the treatment of hypertension

    Article • Blood Pressure, January 2009, Taylor & Francis

    PhD Lona Louring Christrup

  34. The Danish version of the Medication Adherence Report Scale: Preliminary Validation in Cancer Pain Patients

    Article • Pain Practice, January 2009, Wiley

    PhD Lona Louring Christrup

  35. Role of active metabolites in the use of opioids

    Article • European Journal of Clinical Pharmacology, October 2008, Springer Science + Business Media

    PhD Lona Louring Christrup

  36. Pharmacokinetic–Pharmacodynamic Relationships of Cognitive and Psychomotor Effects of Intravenous Buprenorphine Infusion in Human Volunteers

    Article • Basic & Clinical Pharmacology & Toxicology, July 2008, Wiley

    PhD Lona Louring Christrup

  37. Recommended use of morphine in neonates, infants and children based on a literature review: Part 2-Clinical use

    Article • Pediatric Anesthesia, June 2008, Wiley

    PhD Lona Louring Christrup

  38. Pharmacokinetic-Pharmacodynamic Modeling of Morphine and Oxycodone Concentrations and Analgesic Effect in a Multimodal Experimental Pain Model

    Article • The Journal of Clinical Pharmacology, May 2008, Wiley

    PhD Lona Louring Christrup

  39. Population pharmacokinetics of buprenorphine following a two-stage intravenous infusion in healthy volunteers

    Article • European Journal of Clinical Pharmacology, September 2007, Springer Science + Business Media

    PhD Lona Louring Christrup

  40. A new intelligent tablet reminder device – Do health professionals find it of therapeutic value?

    Article • Journal of Medical Marketing Device Diagnostic and Pharmaceutical Marketing, June 2007, SAGE Publications

    PhD Lona Louring Christrup

  41. Pharmacokinetics of morphine-6-glucuronide following oral administration in healthy volunteers

    Article • European Journal of Clinical Pharmacology, May 2007, Springer Science + Business Media

    PhD Lona Louring Christrup

  42. Patient acceptance of a tablet reminder device

    Article • Journal of Medical Marketing Device Diagnostic and Pharmaceutical Marketing, March 2007, SAGE Publications

    PhD Lona Louring Christrup

  43. Differential effect of opioids in patients with chronic pancreatitis: An experimental pain study

    Article • Scandinavian Journal of Gastroenterology, January 2007, Taylor & Francis

    PhD Lona Louring Christrup

  44. A comparative study of oxycodone and morphine in a multi-modal, tissue-differentiated experimental pain model

    Article • Pain, July 2006, Wolters Kluwer Health

    PhD Lona Louring Christrup

  45. Pharmacokinetics of M6G following intravenous and oral administration in healthy volunteers

    Article • Acute Pain, June 2006, Elsevier

    PhD Lona Louring Christrup

  46. Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre

    Article • European Journal of Pain, August 2005, Wiley

    PhD Lona Louring Christrup

  47. Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug

    Article • European Journal of Pharmaceutical Sciences, March 2005, Elsevier

    PhD Lona Louring Christrup

  48. Pharmacological consequences of long-term morphine treatment in patients with cancer and chronic non-malignant pain

    Article • European Journal of Pain, June 2004, Wiley

    PhD Lona Louring Christrup

  49. Medicated Chewing Gum

    Article • American Journal of Drug Delivery, January 2004, Springer Science + Business Media

    PhD Lona Louring Christrup

  50. Relationships Among Morphine Metabolism, Pain and Side Effects During Long-Term Treatment

    Article • Journal of Pain and Symptom Management, January 2003, Elsevier

    PhD Lona Louring Christrup

  51. Changing M3G/M6G Ratios and Pharmacodynamics in a Cancer Patient During Long-Term Morphine Treatment

    Article • Journal of Pain and Symptom Management, February 2002, Elsevier

    PhD Lona Louring Christrup

  52. Steady-State Kinetics and Dynamics of Morphine in Cancer Patients

    Article • Journal of Pain and Symptom Management, September 1999, Elsevier

    PhD Lona Louring Christrup

  53. Opioid analgesics as noncompetitive N-methyl-d-aspartate (NMDA) antagonists

    Article • Biochemical Pharmacology, September 1998, Elsevier

    PhD Lona Louring Christrup

  54. Recommended use of morphine in neonates, infants and children based on a literature review: Part 1—Pharmacokinetics

    Article • Pediatric Anesthesia, January 1997, Wiley

    PhD Lona Louring Christrup

  55. Morphine metabolites

    Article • Acta Anaesthesiologica Scandinavica, January 1997, Wiley

    PhD Lona Louring Christrup

  56. The mu1and mu2opioid receptor binding of ketobemidone, norketobemidone and 3-dimethylamino-1,1-diphenylbutene

    Article • Pharmacology & Toxicology, August 1996, Wiley

    PhD Lona Louring Christrup

  57. Stereoselective Pharmacokinetics of Methadone in Chronic Pain Patients

    Article • Therapeutic Drug Monitoring, June 1996, Wolters Kluwer Health

    PhD Lona Louring Christrup

  58. The mu1, mu2, delta, kappa opioid receptor binding profiles of methadone stereoisomers and morphine

    Article • Life Sciences, December 1994, Elsevier

    PhD Lona Louring Christrup

  59. Buccal absorption of ketobemidone and various ester prodrugs in the rat

    Article • International Journal of Pharmaceutics, December 1992, Elsevier

    PhD Lona Louring Christrup

  60. Enhanced delivery of ketobemidone through porcine buccal mucosa in vitro via more lipophilic ester prodrugs

    Article • International Journal of Pharmaceutics, December 1992, Elsevier

    PhD Lona Louring Christrup

  61. Saliva-catalyzed hydrolysis of a ketobemidone ester prodrug: Factors influencing human salivary esterase activity

    Article • International Journal of Pharmaceutics, December 1992, Elsevier

    PhD Lona Louring Christrup

  62. Ketobemidone prodrugs for buccal delivery: Prediction of the extent of saliva-catalyzed hydrolysis of various ester prodrugs under simulated in vivo conditions

    Article • International Journal of Pharmaceutics, December 1992, Elsevier

    PhD Lona Louring Christrup

  63. Single-Dose and Steady-State Pharmacokinetics of Diltiazem Administered in Two Different Tablet Formulations

    Article • Pharmacology & Toxicology, October 1992, Wiley

    PhD Lona Louring Christrup

  64. Enhanced transdermal delivery of ketobemidone with prodrugs

    Article • International Journal of Pharmaceutics, August 1992, Elsevier

    PhD Lona Louring Christrup

  65. Utilization of prodrugs to enhance the transdermal absorption of morphine

    Article • International Journal of Pharmaceutics, April 1991, Elsevier

    PhD Lona Louring Christrup

  66. Pethidine is Unsuitable for Buccal Administration

    Article • Pharmacology & Toxicology, April 1990, Wiley

    PhD Lona Louring Christrup