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  1. Perspective Strategies for Interventions in Parkinsonism: Remedying the Neglected Role of TPPP

    Article • Cells, February 2024, MDPI AG

    Professor Judit Ovádi, Dr Vic Norris

  2. The Sherpa hypothesis: Phenotype-Preserving Disordered Proteins stabilize the phenotypes of neurons and oligodendrocytes

    Article • npj Systems Biology and Applications, July 2023, Springer Science + Business Media

    Professor Judit Ovádi, Dr Vic Norris

  3. Pharmacological targeting of α‐synuclein and TPPP /p25 in Parkinson's disease: challenges and opportunities in a Nutshell

    Article • FEBS Letters, June 2019, Wiley

    Professor Judit Ovádi

  4. Chemically induced degradation of sirtuin 2 (Sirt2) by a proteolysis targeting chimera (PROTAC) based on sirtuin rearranging ligands (SirReals)

    Article • Journal of Medicinal Chemistry, April 2017, American Chemical Society (ACS)

    Professor Judit Ovádi

  5. Role of the microtubule-associated TPPP/p25 in Parkinson’s and related diseases and its therapeutic potential

    Article • Expert Review of Proteomics, March 2017, Taylor & Francis

    Professor Judit Ovádi

  6. Challenging drug target for Parkinson's disease: Pathological complex of the chameleon TPPP/p25 and alpha-synuclein proteins

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, January 2017, Elsevier

    Professor Judit Ovádi

  7. Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure–Activity Relationship Study

    Article • Journal of Medicinal Chemistry, February 2016, American Chemical Society (ACS)

    Professor Judit Ovádi

  8. Strukturbasierte Entwicklung einer Affinitätssonde für Sirtuin 2

    Article • Angewandte Chemie, December 2015, Wiley

    Professor Judit Ovádi

  9. Targeting the interface of the pathological complex of α-synuclein and TPPP/p25

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, December 2015, Elsevier

    Professor Judit Ovádi

  10. Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomes

    Article • Cell Communication and Signaling, July 2015, Springer Science + Business Media

    Professor Judit Ovádi

  11. Selective Sirt2 inhibition by ligand-induced rearrangement of the active site

    Article • Nature Communications, February 2015, Nature

    Professor Judit Ovádi

  12. Modeling of sensing potency of cytoskeletal systems decorated with metabolic enzymes

    Article • Journal of Theoretical Biology, January 2015, Elsevier

    Professor Judit Ovádi, Dr Vic Norris

  13. Zinc-induced structural changes of the disordered tppp/p25 inhibits its degradation by the proteasome

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, January 2015, Elsevier

    Professor Judit Ovádi

  14. Tubulin acetylation promoting potency and absorption efficacy of deacetylase inhibitors

    Article • British Journal of Pharmacology, December 2014, Wiley

    Professor Judit Ovádi, Marival Bermejo Sanz

  15. Dual life of TPPP/p25 evolved in physiological and pathological conditions

    Article • Biochemical Society Transactions, December 2014, Portland Press Ltd.

    Professor Judit Ovádi

  16. Identification of motives mediating alternative functions of the neomorphic moonlighting TPPP/p25

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, April 2014, Elsevier

    Professor Judit Ovádi

  17. Sensor potency of the moonlighting enzyme-decorated cytoskeleton: the cytoskeleton as a metabolic sensor

    Article • BMC Biochemistry, January 2013, Springer Science + Business Media

    Professor Judit Ovádi, Dr Vic Norris

  18. Microtubule assembly-derived by dimerization of TPPP/p25. Evaluation of thermodynamic parameters for multiple equilibrium system from ITC data

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, July 2012, Elsevier

    Professor Judit Ovádi

  19. Zn2+-Induced Rearrangement of the Disordered TPPP/p25 Affects Its Microtubule Assembly and GTPase Activity

    Article • Biochemistry, November 2011, American Chemical Society (ACS)

    Professor Judit Ovádi

  20. Moonlighting proteins in neurological disorders

    Article • IUBMB Life, June 2011, Wiley

    Professor Judit Ovádi

  21. A new myelin protein, TPPP/p25, reduced in demyelinated lesions is enriched in cerebrospinal fluid of multiple sclerosis

    Article • Biochemical and Biophysical Research Communications, May 2011, Elsevier

    Professor Judit Ovádi

  22. Proteins without 3D structure: definition, detection and beyond

    Article • Bioinformatics, April 2011, Oxford University Press (OUP)

    Professor Judit Ovádi

  23. Disordered TPPP/p25 binds GTP and displays Mg2+-dependent GTPase activity

    Article • FEBS Letters, February 2011, Wiley

    Professor Judit Ovádi

  24. Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis

    Article • Glia, August 2010, Wiley

    Professor Judit Ovádi, Prof. Herbert Budka

  25. Reappraisal of triosephosphate isomerase deficiency

    Article • European Journal Of Haematology, June 2010, Wiley

    Professor Judit Ovádi

  26. Triosephosphate isomerase deficiency: New insights into an enigmatic disease

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, December 2009, Elsevier

    Professor Judit Ovádi

  27. Tubulin polymerization-promoting protein (TPPP/p25) is critical for oligodendrocyte differentiation

    Article • Glia, July 2009, Wiley

    Professor Judit Ovádi

  28. An unstructured protein with destructive potential: TPPP/p25 in neurodegeneration

    Article • BioEssays, June 2009, Wiley

    Professor Judit Ovádi

  29. Unique pharmacology of KAR-2, a potential anti-cancer agent: Absorption modelling and selective mitotic spindle targeting

    Article • European Journal of Pharmaceutical Sciences, January 2009, Elsevier

    Professor Judit Ovádi, Marival Bermejo Sanz

  30. ChemInform Abstract: Conformationally Constrained Adamantaneoxazolines of Pharmacological Interest.

    Article • ChemInform, December 2008, Wiley

    Ioannis P. Papanastasiou , Professor Judit Ovádi

  31. TPPP orthologs are ciliary proteins

    Article • FEBS Letters, October 2008, Wiley

    Professor Judit Ovádi

  32. The tubulin polymerization promoting protein, TPPP/p25

    Article • IUBMB Life, September 2008, Wiley

    Professor Judit Ovádi

  33. Increased glucose metabolism and ATP level in brain tissue of Huntington’s disease transgenic mice

    Article • FEBS Journal, August 2008, Wiley

    Professor Judit Ovádi

  34. Triosephosphate isomerase deficiency: Facts and doubts

    Article • IUBMB Life, December 2006, Wiley

    Professor Judit Ovádi

  35. TPPP/p25 in brain tumours: expression in non-neoplastic oligodendrocytes but not in oligodendroglioma cells

    Article • Acta Neuropathologica, November 2006, Springer Science + Business Media

    Professor Judit Ovádi, Prof. Herbert Budka

  36. The brain-specific protein TPPP/p25 in pathological protein deposits of neurodegenerative diseases

    Article • Acta Neuropathologica, November 2006, Springer Science + Business Media

    Professor Judit Ovádi, Prof. Herbert Budka

  37. Tubulin Polymerization Promoting Proteins (TPPPs):  Members of a New Family with Distinct Structures and Functions†

    Article • Biochemistry, November 2006, American Chemical Society (ACS)

    Professor Judit Ovádi

  38. Interaction of TPPP/p25 protein with glyceraldehyde-3-phosphate dehydrogenase and their co-localization in Lewy bodies

    Article • FEBS Letters, September 2006, Wiley

    Professor Judit Ovádi

  39. Spotlight on…Judit Ovádi

    Article • FEBS Letters, April 2006, Wiley

    Professor Judit Ovádi

  40. Triosephosphate isomerase deficiency: consequences of an inherited mutation at mRNA, protein and metabolic levels

    Article • Biochemical Journal, December 2005, Portland Press Ltd.

    Professor Judit Ovádi

  41. Structure of Calmodulin in complex with KAR-2, a bis-indol alkaloid

    Article • December 2004, Protein Data Bank, Rutgers University

    Professor Judit Ovádi

  42. Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies

    Article • Neurobiology of Disease, November 2004, Elsevier

    Professor Judit Ovádi, Prof. Herbert Budka

  43. Functional aspects of cellular microcompartmentation in the development of neurodegeneration: Mutation induced aberrant protein-protein associations

    Article • Molecular and Cellular Biochemistry, January 2004, Springer Science + Business Media

    Professor Judit Ovádi

  44. Glucose conversion by multiple pathways in brain extract: theoretical and experimental analysis

    Article • Biochemical and Biophysical Research Communications, October 2003, Elsevier

    Professor Judit Ovádi

  45. A simple method for the determination of dissociation constants by displacement ELISA

    Article • Journal of Immunological Methods, December 2002, Elsevier

    Professor Judit Ovádi

  46. Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease

    Article • Biochemical Society Transactions, April 2002, Portland Press Ltd.

    Professor Judit Ovádi

  47. Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease

    Article • Biochemical Society Transactions, February 2002, Portland Press Ltd.

    Professor Judit Ovádi

  48. Dedications to Paul Srere

    Article • Biochemical Society Transactions, February 2002, Portland Press Ltd.

    Professor Judit Ovádi

  49. Phosphofructokinases

    Article • January 2002, Wiley

    Professor Judit Ovádi

  50. Tubulin and microtubule are potential targets for brain hexokinase binding

    Article • FEBS Letters, November 2001, Wiley

    Professor Judit Ovádi

  51. Triosephosphate isomerase deficiency: a neurodegenerative misfolding disease

    Article • Biochemical Society Transactions, April 2001, Portland Press Ltd.

    Professor Judit Ovádi

  52. Organization-dependent effects of toxic bivalent ions

    Article • European Journal of Biochemistry, August 2000, Wiley

    Professor Judit Ovádi

  53. Quantitative characterization of homo- and heteroassociations of muscle phosphofructokinase with aldolase

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, June 2000, Elsevier

    Professor Judit Ovádi

  54. Implications of Cytoarchitectural Analysis

    Article • January 2000, Springer Science + Business Media

    Professor Judit Ovádi

  55. Substrate Channeling

    Article • Methods, October 1999, Elsevier

    Professor Judit Ovádi

  56. Paul A. Srere (1925–1999)

    Article • Methods, October 1999, Elsevier

    Professor Judit Ovádi

  57. Combined Enhancement of Microtubule Assembly and Glucose Metabolism in Neuronal Systems in Vitro: Decreased Sensitivity to Copper Toxicity

    Article • Biochemical and Biophysical Research Communications, October 1999, Elsevier

    Professor Judit Ovádi

  58. Application of metabolic control analysis to the study of toxic effects of copper in muscle glycolysis

    Article • FEBS Letters, February 1999, Wiley

    Professor Judit Ovádi

  59. Phosphofructokinase from Dictyostelium discoideum Is a Potent Inhibitor of Tubulin Polymerization †

    Article • Biochemistry, February 1999, American Chemical Society (ACS)

    Professor Judit Ovádi

  60. Macromolecular Compartmentation and Channeling

    Article • January 1999, Elsevier

    Professor Judit Ovádi

  61. Pyruvate Kinase as a Microtubule Destabilizing Factorin Vitro

    Article • Biochemical and Biophysical Research Communications, January 1999, Elsevier

    Professor Judit Ovádi

  62. CALMODULIN COMPLEXED WITH TRIFLUOPERAZINE (1:2 COMPLEX)

    Article • September 1998, Protein Data Bank, Rutgers University

    Professor Judit Ovádi

  63. Comparison of control analysis data using different approaches: modelling and experiments with muscle extract

    Article • FEBS Letters, November 1997, Wiley

    Professor Judit Ovádi

  64. Interaction of a new bis-indol derivative, KAR-2 with tubulin and its antimitotic activity

    Article • British Journal of Pharmacology, July 1997, Wiley

    Professor Judit Ovádi

  65. Crystallization and preliminary diffraction analysis of Ca2+-calmodulin-drug and apocalmodulin-drug complexes

    Article • Proteins Structure Function and Bioinformatics, May 1997, Wiley

    Professor Judit Ovádi

  66. Characterization of Microtubule−Phosphofructokinase Complex:  Specific Effects of MgATP and Vinblastine †

    Article • Biochemistry, February 1997, American Chemical Society (ACS)

    Professor Judit Ovádi

  67. Metabolic Consequences of Enzyme Interactions

    Article • Cell Biochemistry and Function, December 1996, Wiley

    Professor Judit Ovádi

  68. Metabolic consequences of enzyme interactions

    Article • Cell Biochemistry and Function, December 1996, Wiley

    Professor Judit Ovádi

  69. Specific characteristics of phosphofructokinase-microtubule interaction

    Article • FEBS Letters, January 1996, Wiley

    Professor Judit Ovádi

  70. Anti-calmodulin potency of indol alkaloids in in vitro systems

    Article • European Journal of Pharmacology Molecular Pharmacology, October 1995, Elsevier

    Professor Judit Ovádi

  71. Binding of malate dehydrogenase and NADH channelling to complex I

    Article • Journal of Molecular Recognition, December 1994, Wiley

    Professor Judit Ovádi

  72. Channel your energies

    Article • Trends in Biochemical Sciences, November 1992, Elsevier

    Professor Judit Ovádi

  73. Calmodulin and Dynamics of Interactions of Cytosolic Enzymes

    Article • January 1992, Elsevier

    Professor Judit Ovádi

  74. Quantitative evaluation of indirect ELISA effect of calmodulin antagonists on antibody binding to calmodulin

    Article • Journal of Immunological Methods, September 1991, Elsevier

    Professor Judit Ovádi

  75. Modulation of the interaction between aldolase and glycerol-phosphate dehydrogenase by fructose phosphates

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, June 1991, Elsevier

    Professor Judit Ovádi

  76. Calmodulin is a potent target for new hypothalamic neuropeptides

    Article • FEBS Letters, December 1990, Wiley

    Professor Judit Ovádi

  77. Enzyme-enzyme interactions and their metabolic role

    Article • FEBS Letters, August 1990, Wiley

    Professor Judit Ovádi

  78. Structurally distinct mammalian calmodulins

    Article • Immunology Letters, May 1990, Elsevier

    Professor Judit Ovádi

  79. Cooperative effect of fructose bisphosphate and glyceraldehyde-3-phosphate dehydrogenase on aldolase action

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, March 1990, Elsevier

    Professor Judit Ovádi

  80. Tamás Keleti (1927–1989)

    Article • Trends in Biochemical Sciences, February 1990, Elsevier

    Professor Judit Ovádi

  81. Channelling and Channel Efficiency: Theory and Analytical Implications

    Article • January 1990, Springer Science + Business Media

    Professor Judit Ovádi

  82. Effects of drugs on calmodulin-mediated enzymatic actions

    Article • January 1989, Springer Science + Business Media

    Professor Judit Ovádi

  83. Kinetic and physico-chemical analysis of enzyme complexes and their possible role in the control of metabolism

    Article • Progress in Biophysics and Molecular Biology, January 1989, Elsevier

    Professor Judit Ovádi

  84. Old pathway — new concept: control of glycolysis by metabolite- modulated dynamic enzyme associations

    Article • Trends in Biochemical Sciences, December 1988, Elsevier

    Professor Judit Ovádi

  85. Modulation of phosphofructokinase action by macromolecular interactions. Quantitative analysis of the phosphofructokinase-aldolase-calmodulin system

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, November 1988, Elsevier

    Professor Judit Ovádi

  86. Control of Metabolism by Dynamic Macromolecular Interactions

    Article • January 1988, Elsevier

    Professor Judit Ovádi

  87. Aldolase decreases the dissociation-induced inactivation of muscle phosphofructokinase

    Article • Biochemical and Biophysical Research Communications, September 1987, Elsevier

    Professor Judit Ovádi

  88. A simple approach to identify the mechanism of intermediate transfer: enzyme system related to triose phosphate metabolism

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, September 1987, Elsevier

    Professor Judit Ovádi

  89. A simple approach to detect active-site-directed enzyme-enzyme interactions. The aldolase/glycerol-phosphate-dehydrogenase enzyme system

    Article • European Journal of Biochemistry, May 1987, Wiley

    Professor Judit Ovádi

  90. How to determine the efficiency of intermediate transfer in an interacting enzyme system?

    Article • FEBS Letters, April 1987, Wiley

    Professor Judit Ovádi

  91. Quantitative determination of triosephosphates during enzymatic reaction by high performance liquid chromatography: effect of isomerase on aldolase activity

    Article • Journal of Biochemical and Biophysical Methods, December 1986, Elsevier

    Professor Judit Ovádi

  92. Dynamic interactions of enzymes involved in triosephosphate metabolism

    Article • European Journal of Biochemistry, November 1986, Wiley

    Professor Judit Ovádi

  93. Isolation and quantitative determination of some cardioactive glycosides from Digitalis lanata by high-performance liquid chromatography

    Article • Analytical Biochemistry, July 1986, Elsevier

    Professor Judit Ovádi

  94. Phosphofructokinase and fructosebisphosphatase from muscle can interact at physiological concentrations with mutual effects on their kinetic behavior

    Article • Biochemical and Biophysical Research Communications, March 1986, Elsevier

    Professor Judit Ovádi

  95. Interaction of the Dissociable Glycerol-3-phosphate Dehydrogenase and Fructose-1,6-bisphosphate Aldolase. Quantitative Analysis by an Extrinsic Fluorescence Probe

    Article • European Journal of Biochemistry, June 1983, Wiley

    Professor Judit Ovádi

  96. Interaction between D-Fructose-1,6-bisphosphate aldolase and triosephosphate isomerase

    Article • FEBS Letters, February 1982, Wiley

    Professor Judit Ovádi

  97. Kinetics of Coupled Reactions Catalyzed by Aspartate Aminotransferase and Glutamate Dehydrogenase

    Article • European Journal of Biochemistry, January 1982, Wiley

    Professor Judit Ovádi

  98. Physico-chemical Evidence for the Interaction between Aldolase and Glyceraldehyde-3-phosphate Dehydrogenase

    Article • European Journal of Biochemistry, October 1978, Wiley

    Professor Judit Ovádi

  99. SH groups masked by subunit interaction in glyceraldehyde-3-phosphate dehydrogenase

    Article • Biochimica et Biophysica Acta (BBA) - Enzymology, April 1973, Elsevier

    Professor Judit Ovádi

  100. TPPP/p25: A New Unstructured Protein Hallmarking Synucleinopathies

    Article • Springer Science + Business Media

    Professor Judit Ovádi