All Stories

  1. The problem of racemization in drug discovery and tools to predict it

    Article • Expert Opinion on Drug Discovery, March 2019, Taylor & Francis

    Dr Andrew G Leach

  2. A mechanistic proposal for the protodeboronation of neat boronic acids: boronic acid mediated reaction in the solid state

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Dr Andrew G Leach

  3. Novel N-thiazolyl piperazine-1-carboxamide CCR2 antagonists – investigation of an unexpected reaction with glutathione

    Article • MedChemComm, January 2015, Royal Society of Chemistry

    Dr Andrew G Leach

  4. Predicting the activity and toxicity of new psychoactive substances: a pharmaceutical industry perspective

    Article • Drug Testing and Analysis, December 2013, Wiley

    Dr Andrew G Leach

  5. Reaction energies computed with density functional theory correspond with a whole organism effect; modelling the Ames test for mutagenicity

    Article • Chemical Communications, January 2009, Royal Society of Chemistry

    Dr Andrew G Leach