All Stories

  1. ChemInform Abstract: Regioselective Conversion of Arenes to N-Aryl-1,2,3-triazoles Using C-H Borylation.

    Article • ChemInform, February 2015, Wiley

    Dr Anthony G Coyne

  2. Understanding “On-Water” Catalysis of Organic Reactions. Effects of H + and Li + Ions in the Aqueous Phase and Nonreacting Competitor H-Bond Acceptors in the Organic Phase: On H 2 O versus on D 2 O for Huisgen Cycloadditions

    Article • The Journal of Organic Chemistry, February 2015, American Chemical Society (ACS)

    Dr Anthony G Coyne

  3. Small-Molecule Inhibitors That Target Protein-Protein Interactions in the RAD51 Family of Recombinases

    Article • ChemMedChem, December 2014, Wiley

    Dr Anthony G Coyne

  4. Regioselective Conversion of Arenes toN-aryl-1,2,3-triazoles Using CH Borylation

    Article • Chemistry - A European Journal, July 2014, Wiley

    Dr Anthony G Coyne

  5. Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting Mycobacterium tuberculosis CYP121

    Article • ChemMedChem, June 2013, Wiley

    Dr Anthony G Coyne

  6. Water and Organic Synthesis: A Focus on the In-Water and On-Water Border. Reversal of the In-Water Breslow Hydrophobic Enhancement of the Normal endo -Effect on Crossing to On-Water Conditions for Huisgen Cycloadditions with Increasingly Insoluble Org...

    Article • The Journal of Organic Chemistry, April 2013, American Chemical Society (ACS)

    Dr Anthony G Coyne

  7. Fragment-Based Approaches in Drug Discovery and Chemical Biology

    Article • Biochemistry, June 2012, American Chemical Society (ACS)

    Dr Anthony G Coyne

  8. ChemInform Abstract: Asymmetric Electrocyclic Reactions

    Article • ChemInform, November 2011, Wiley

    Dr Anthony G Coyne

  9. ChemInform Abstract: Water: Nature′s Reaction Enforcer-Comparative Effects for Organic Synthesis “In-Water” and “On-Water”

    Article • ChemInform, June 2011, Wiley

    Dr Anthony G Coyne

  10. Asymmetric electrocyclic reactions

    Article • Chemical Society Reviews, January 2011, Royal Society of Chemistry

    Dr Anthony G Coyne

  11. Water: Nature’s Reaction Enforcer—Comparative Effects for Organic Synthesis “In-Water” and “On-Water”

    Article • Chemical Reviews, October 2010, American Chemical Society (ACS)

    Dr Anthony G Coyne

  12. Drugging challenging targets using fragment-based approaches

    Article • Current Opinion in Chemical Biology, June 2010, Elsevier

    Dr Anthony G Coyne

  13. ChemInform Abstract: Regioselectivity and endo/exo Selectivity in the Cycloadditions of the Phthalazinium Dicyanomethanide 1,3-Dipole with Unsymmetrical Alkene and Alkyne Dipolarophiles. Unexpected Reversals of Regiochemistry: A Combined Experimental and

    Article • ChemInform, May 2010, Wiley

    Dr Anthony G Coyne

  14. ChemInform Abstract: Ligand Design for Intermolecular Asymmetric Mizoroki-Heck Reactions

    Article • ChemInform, May 2010, Wiley

    Dr Anthony G Coyne

  15. ChemInform Abstract: The Development and Application of Rhodium-Catalyzed Hydroboration of Alkenes

    Article • ChemInform, September 2009, Wiley

    Dr Anthony G Coyne

  16. Uncharacteristic thione behavior in a Huisgen cycloaddition reaction: a kinetic and theoretical study

    Article • Tetrahedron Letters, September 2007, Elsevier

    Dr Anthony G Coyne

  17. Organic Synthesis in Water: 1,3-Dipolar Cycloaddition Reactions at Ambient Temperature with Aqueous Suspensions of Solid Reactants.

    Article • ChemInform, August 2007, Wiley

    Dr Anthony G Coyne

  18. The Asymmetric Synthesis of β-Lactams: HETPHOX/Cu(I) Mediated Synthesis via the Kinugasa Reaction.

    Article • ChemInform, July 2007, Wiley

    Dr Anthony G Coyne

  19. Organic synthesis in water: 1,3-dipolar cycloaddition reactions at ambient temperature with aqueous suspensions of solid reactants

    Article • Tetrahedron Letters, May 2007, Elsevier

    Dr Anthony G Coyne

  20. Rhodium-Catalyzed Asymmetric Hydrosilylation of Ketones Using HETPHOX Ligands.

    Article • ChemInform, April 2007, Wiley

    Dr Anthony G Coyne

  21. The asymmetric synthesis of β-lactams: HETPHOX/Cu(I) mediated synthesis via the Kinugasa reaction

    Article • Tetrahedron Asymmetry, February 2007, Elsevier

    Dr Anthony G Coyne, Professor Patrick J Guiry

  22. Rhodium-catalysed asymmetric hydrosilylation of ketones using HETPHOX ligands

    Article • Tetrahedron Letters, January 2007, Elsevier

    Dr Anthony G Coyne, Professor Patrick J Guiry

  23. The Application of HETPHOX Ligands to the Intramolecular Asymmetric Heck Reaction

    Article • Synlett, November 2006, Thieme Publishing Group

    Dr Anthony G Coyne, Professor Patrick J Guiry

  24. Water and theHuisgen Cycloaddition Reaction: A Focus on Polar Contributions to the Transition State in the Reactions of Dicyano(phthalazinium)methanide with Substituted Styrenes and Benzylidene Acetones

    Article • Helvetica Chimica Acta, July 2005, Wiley

    Dr Anthony G Coyne

  25. The Influence of Water on the Rates of 1,3-Dipolar Cycloaddition Reactions:  Trigger Points for Exponential Rate Increases in Water−Organic Solvent Mixtures. Water-Super versus Water-Normal Dipolarophiles

    Article • Journal of the American Chemical Society, September 2004, American Chemical Society (ACS)

    Dr Anthony G Coyne

  26. Kinetic and synthetic influences of water and solvent-free conditions on 1,3-dipolar cycloaddition reactions: the phthalazinium and pyridazinium dicyanomethanide 1,3-dipoles: surprisingly successful synthetic methodsElectronic supplementary information...

    Article • Journal of the Chemical Society Perkin Transactions 2, October 2002, Royal Society of Chemistry

    Dr Anthony G Coyne

  27. The kinetic profile of phthalazinium-2-dicyanomethanide 1,3-dipole with 2π-dipolarophiles: U-shaped dipolarophilic activity and classic type II dipole behaviour. Reaction rates and DFT calculations

    Article • Journal of the Chemical Society Perkin Transactions 2, January 2001, Royal Society of Chemistry

    Dr Anthony G Coyne

  28. Regioselectivity and endo/exo selectivity in the cycloadditions of the phthalazinium dicyanomethanide 1,3-dipole with unsymmetrical alkene and alkyne dipolarophiles. Unexpected reversals of regiochemistry: a combined experimental and DFT theoretical study

    Article • Journal of the Chemical Society Perkin Transactions 1, January 2001, Royal Society of Chemistry

    Dr Anthony G Coyne

  29. Ligand Design for Intermolecular Asymmetric Mizoroki–Heck Reactions

    Article • Wiley

    Dr Anthony G Coyne

  30. The Development and Application of Rhodium-Catalyzed Hydroboration of Alkenes

    Article • Wiley

    Dr Anthony G Coyne, Professor Patrick J Guiry