All Stories

  1. Design and implementation of a microfluidic device capable of temporal growth factor delivery reveal filtering capabilities of the EGFR/ERK pathway

    Article • APL Bioengineering, December 2021, American Institute of Physics

    Dr Megan Nicole McClean

  2. Shining light on molecular communication

    Article • September 2020, ACM (Association for Computing Machinery)

    Dr Megan Nicole McClean

  3. A yeast optogenetic toolkit (yOTK) for gene expression control in Saccharomyces cerevisiae

    Article • Biotechnology and Bioengineering, December 2019, Wiley

    Dr Megan Nicole McClean

  4. Optogenetic Repressors of Gene Expression in Yeasts Using Light-Controlled Nuclear Localization

    Article • Cellular and Molecular Bioengineering, September 2019, Springer Science + Business Media

    Dr Megan Nicole McClean

  5. Easy calibration of the Light Plate Apparatus for optogenetic experiments

    Article • MethodsX, January 2019, Elsevier

    Dr Megan Nicole McClean

  6. Single-cell RNA sequencing reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress

    Article • PLoS Biology, December 2017, PLOS

    Dr Megan Nicole McClean

  7. Engineered bacteria self-organize to sense pressure

    Article • Nature Biotechnology, October 2017, Nature

    Dr Megan Nicole McClean

  8. Design and Implementation of an Automated Illuminating, Culturing, and Sampling System for Microbial Optogenetic Applications

    Article • Journal of Visualized Experiments, February 2017, MyJove Corporation

    Dr Megan Nicole McClean

  9. Robust network structure of the Sln1-Ypd1-Ssk1 three-component phospho-relay prevents unintended activation of the HOG MAPK pathway in Saccharomyces cerevisiae

    Article • BMC Systems Biology, March 2015, Springer Science + Business Media

    Dr Megan Nicole McClean

  10. Real-time optogenetic control of intracellular protein concentration in microbial cell cultures

    Article • Integrative Biology, January 2014, Oxford University Press (OUP)

    Dr Megan Nicole McClean

  11. Microfluidic Platforms for Generating Dynamic Environmental Perturbations to Study the Responses of Single Yeast Cells

    Article • January 2014, Springer Science + Business Media

    Dr Megan Nicole McClean

  12. A New System for Comparative Functional Genomics of Saccharomyces Yeasts

    Article • Genetics, July 2013, Genetics Society of America

    Dr Megan Nicole McClean

  13. Visualization and Analysis of mRNA Molecules Using Fluorescence In Situ Hybridization in Saccharomyces cerevisiae

    Article • Journal of Visualized Experiments, June 2013, MyJove Corporation

    Dr Megan Nicole McClean

  14. Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses

    Article • Molecular Biology of the Cell, April 2013, American Society for Cell Biology (ASCB)

    Dr Megan Nicole McClean

  15. Severe osmotic compression triggers a slowdown of intracellular signaling, which can be explained by molecular crowding

    Article • Proceedings of the National Academy of Sciences, March 2013, Proceedings of the National Academy of Sciences

    Dr Megan Nicole McClean

  16. Fast-acting and nearly gratuitous induction of gene expression and protein depletion in Saccharomyces cerevisiae

    Article • Molecular Biology of the Cell, September 2011, American Society for Cell Biology (ASCB)

    Dr Megan Nicole McClean

  17. Measuring In Vivo Signaling Kinetics in a Mitogen-Activated Kinase Pathway Using Dynamic Input Stimulation

    Article • January 2011, Springer Science + Business Media

    Dr Megan Nicole McClean

  18. The Dynamical Systems Properties of the HOG Signaling Cascade

    Article • Journal of Signal Transduction, January 2011, Hindawi Publishing Corporation

    Dr Megan Nicole McClean

  19. In vivo measurement of signaling cascade dynamics

    Article • Cell Cycle, February 2009, Taylor & Francis

    Dr Megan Nicole McClean

  20. Analyse dynamique de la signalisation cellulaire

    Article • médecine/sciences, December 2008, EDP Sciences

    Dr Megan Nicole McClean

  21. Signal processing by the HOG MAP kinase pathway

    Article • Proceedings of the National Academy of Sciences, May 2008, Proceedings of the National Academy of Sciences

    Dr Megan Nicole McClean

  22. Erratum: Corrigendum: Cross-talk and decision making in MAP kinase pathways

    Article • Nature Genetics, April 2007, Springer Science + Business Media

    Dr Megan Nicole McClean

  23. Cross-talk and decision making in MAP kinase pathways

    Article • Nature Genetics, January 2007, Springer Science + Business Media

    Dr Megan Nicole McClean