All Stories

  1. Switchable asymmetric bio-epoxidation of α,β-unsaturated ketones

    Article • Chemical Communications, January 2016, Royal Society of Chemistry

    Professor Zhong-Liu Wu

  2. Bioreductive production of enantiopure (S)-duloxetine intermediates catalyzed with ketoreductase ChKRED15

    Article • Journal of Molecular Catalysis B Enzymatic, March 2015, Elsevier

    Professor Zhong-Liu Wu

  3. Synthesis of enantiopure glycidol derivatives via a one-pot two-step enzymatic cascade

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Professor Zhong-Liu Wu

  4. Identification and characterization of a novel “thermophilic-like” Old Yellow Enzyme from the genome of Chryseobacterium sp. CA49

    Article • Journal of Molecular Catalysis B Enzymatic, October 2014, Elsevier

    Professor Zhong-Liu Wu

  5. Characterization of a robust anti-Prelog short-chain dehydrogenase/reductase ChKRED20 from Chryseobacterium sp. CA49

    Article • Journal of Molecular Catalysis B Enzymatic, July 2014, Elsevier

    Professor Zhong-Liu Wu

  6. Identification of ketone reductase ChKRED20 from the genome of Chryseobacterium sp. CA49 for highly efficient anti-Prelog reduction of 3,5-bis(trifluoromethyl)acetophenone

    Article • Journal of Molecular Catalysis B Enzymatic, April 2014, Elsevier

    Professor Zhong-Liu Wu

  7. An enoate reductase Achr-OYE4 from Achromobacter sp. JA81: characterization and application in asymmetric bioreduction of C=C bonds

    Article • Applied Microbiology and Biotechnology, May 2013, Springer Science + Business Media

    Professor Zhong-Liu Wu

  8. Design of mutants for enhanced thermostability of β-glycosidase BglY from Thermus thermophilus

    Article • Bioresource Technology, February 2013, Elsevier

    Professor Zhong-Liu Wu

  9. Mutations at the putative active cavity of styrene monooxygenase: Enhanced activity and reversed enantioselectivity

    Article • Journal of Biotechnology, October 2012, Elsevier

    Professor Zhong-Liu Wu

  10. Multiple amino acid substitutions significantly improve the thermostability of feruloyl esterase A from Aspergillus niger

    Article • Bioresource Technology, August 2012, Elsevier

    Professor Zhong-Liu Wu

  11. Asymmetric bioreduction of activated alkenes by a novel isolate of Achromobacter species producing enoate reductase

    Article • Applied Microbiology and Biotechnology, April 2012, Springer Science + Business Media

    Professor Zhong-Liu Wu

  12. A practical high-throughput screening system for feruloyl esterases: Substrate design and evaluation

    Article • Journal of Molecular Catalysis B Enzymatic, January 2012, Elsevier

    Professor Zhong-Liu Wu

  13. Biocatalysis as an alternative for the production of chiral epoxides: A comparative review

    Article • Journal of Molecular Catalysis B Enzymatic, November 2011, Elsevier

    Professor Zhong-Liu Wu

  14. ChemInform Abstract: Asymmetric Epoxidation of Styrene Derivatives by Styrene Monooxygenase from Pseudomonas sp. LQ26: Effects of α- and β-Substituents

    Article • ChemInform, June 2011, Wiley

    Professor Zhong-Liu Wu

  15. ChemInform Abstract: Highly Diastereo- and Enantio-Selective Epoxidation of Secondary Allylic Alcohols Catalyzed by Styrene Monooxygenase.

    Article • ChemInform, May 2011, Wiley

    Professor Zhong-Liu Wu

  16. Highly enantioselective bioreduction of N-methyl-3-oxo-3-(thiophen-2-yl) propanamide for the production of (S)-duloxetine

    Article • Biotechnology Letters, March 2011, Springer Science + Business Media

    Professor Zhong-Liu Wu

  17. Introduction of glycine and proline residues onto protein surface increases the thermostability of endoglucanase CelA from Clostridium thermocellum

    Article • Bioresource Technology, February 2011, Elsevier

    Professor Zhong-Liu Wu

  18. Three amino acid changes contribute markedly to the thermostability of β-glucosidase BglC from Thermobifida fusca

    Article • Bioresource Technology, February 2011, Elsevier

    Professor Zhong-Liu Wu

  19. Highly diastereo- and enantio-selective epoxidation of secondary allylic alcohols catalyzed by styrene monooxygenase

    Article • Chemical Communications, January 2011, Royal Society of Chemistry

    Professor Zhong-Liu Wu

  20. Asymmetric epoxidation of styrene derivatives by styrene monooxygenase from Pseudomonas sp. LQ26: effects of α- and β-substituents

    Article • Tetrahedron Asymmetry, January 2011, Elsevier

    Professor Zhong-Liu Wu

  21. Identification of amino acid residues responsible for increased thermostability of feruloyl esterase A from Aspergillus niger using the PoPMuSiC algorithm

    Article • Bioresource Technology, January 2011, Elsevier

    Professor Zhong-Liu Wu

  22. Improving the thermostability of Geobacillus stearothermophilus xylanase XT6 by directed evolution and site-directed mutagenesis

    Article • Bioresource Technology, December 2010, Elsevier

    Professor Zhong-Liu Wu

  23. Styrene monooxygenase from Pseudomonas sp. LQ26 catalyzes the asymmetric epoxidation of both conjugated and unconjugated alkenes

    Article • Journal of Molecular Catalysis B Enzymatic, December 2010, Elsevier

    Professor Zhong-Liu Wu

  24. Rational design of styrene monooxygenase mutants with altered substrate preference

    Article • Biotechnology Letters, November 2010, Springer Science + Business Media

    Professor Zhong-Liu Wu

  25. Mutations from a family-shuffling-library reveal amino acid residues responsible for the thermostability of endoglucanase CelA from Clostridium thermocellum

    Article • Biotechnology Letters, July 2010, Springer Science + Business Media

    Professor Zhong-Liu Wu

  26. ChemInform Abstract: Enantioselective Hydrolysis of Various Racemic α-Substituted Arylacetonitriles Using Rhodococcus sp. CGMCC 0497.

    Article • ChemInform, May 2010, Wiley

    Professor Zhong-Liu Wu

  27. Human cytochrome P450 4F11: Heterologous expression in bacteria, purification, and characterization of catalytic function

    Article • Archives of Biochemistry and Biophysics, February 2010, Elsevier

    Professor Zhong-Liu Wu

  28. Enhanced bacterial expression of several mammalian cytochrome P450s by codon optimization and chaperone coexpression

    Article • Biotechnology Letters, June 2009, Springer Science + Business Media

    Professor Zhong-Liu Wu

  29. Identification of amino acid residues involved in 4-chloroindole 3-hydroxylation by cytochrome P450 2A6 using screening of random libraries

    Article • Journal of Biotechnology, January 2009, Elsevier

    Professor Zhong-Liu Wu

  30. Heterologous expression, purification, and properties of human cytochrome P450 27C1

    Article • Archives of Biochemistry and Biophysics, January 2006, Elsevier

    Professor Zhong-Liu Wu

  31. Function of human cytochrome P450s: Characterization of the orphans

    Article • Biochemical and Biophysical Research Communications, December 2005, Elsevier

    Professor Zhong-Liu Wu

  32. Enantioselective Biotransformation of α,α-Disubstituted Dinitriles to the Corresponding 2-Cyanoacetamides Using Rhodococcus sp. CGMCC 0497.

    Article • ChemInform, November 2003, Wiley

    Professor Zhong-Liu Wu

  33. Enantioselective biotransformation of α,α-disubstituted dinitriles to the corresponding 2-cyanoacetamides using Rhodococcus sp. CGMCC 0497

    Article • Tetrahedron Asymmetry, August 2003, Elsevier

    Professor Zhong-Liu Wu

  34. Practical Synthesis of Optically Active α,α-Disubstituted Malonamic Acids Through Asymmetric Hydrolysis of Malonamide Derivatives with Rhodococcus sp. CGMCC 0497.

    Article • ChemInform, July 2003, Wiley

    Professor Zhong-Liu Wu

  35. Highly Enantioselective Synthesis of α,α-Disubstituted Malonamic Acids Through Asymmetric Hydrolysis of Dinitriles with Rhodococcus sp. CGMCC 0497.

    Article • ChemInform, June 2003, Wiley

    Professor Zhong-Liu Wu

  36. Biocatalytic asymmetric hydrolysis of (±)-β-hydroxy nitriles by Rhodococcus sp. CGMCC 0497

    Article • Journal of Molecular Catalysis B Enzymatic, April 2003, Elsevier

    Professor Zhong-Liu Wu

  37. Practical Synthesis of Optically Active α,α-Disubstituted Malonamic Acids through Asymmetric Hydrolysis of Malonamide Derivatives with Rhodococcus sp. CGMCC 0497

    Article • The Journal of Organic Chemistry, March 2003, American Chemical Society (ACS)

    Professor Zhong-Liu Wu

  38. Highly enantioselective synthesis of α,α-disubstituted malonamic acids through asymmetric hydrolysis of dinitriles with Rhodococcus sp. CGMCC 0497Electronic supplementary information (ESI) available: full experimental details. See http://www.rsc.org/su...

    Article • Chemical Communications, January 2003, Royal Society of Chemistry

    Professor Zhong-Liu Wu

  39. Enhancement of enzyme activity and enantioselectivity via cultivation in nitrile metabolism by Rhodococcus sp. CGMCC 0497

    Article • Biotechnology and Applied Biochemistry, February 2002, Wiley

    Professor Zhong-Liu Wu

  40. Enantioselective hydrolysis of various racemic α-substituted arylacetonitriles using Rhodococcus sp. CGMCC 0497

    Article • Tetrahedron Asymmetry, December 2001, Elsevier

    Professor Zhong-Liu Wu