All Stories

  1. “Click Chip” Conjugation of Bifunctional Chelators to Biomolecules
  2. A Clickable Analogue of Ketamine Retains NMDA Receptor Activity, Psychoactivity, and Accumulates in Neurons
  3. Microfluidic radio labeling of Herceptin
  4. Synthesis, pharmacological evaluation and molecular modeling studies of triazole containing dopamine D3 receptor ligands
  5. Development of a microfluidic “click chip” incorporating an immobilized Cu(i) catalyst
  6. Triazine-Based Tool Box for Developing Peptidic PET Imaging Probes: Syntheses, Microfluidic Radiolabeling, and Structure–Activity Evaluation
  7. Thiolene and SIFEL-based microfluidic platforms for liquid–liquid extraction
  8. A Digital Revolution in Radiosynthesis
  9. Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands
  10. Microfluidic radiolabeling of biomolecules with PET radiometals
  11. Comparison of the Binding and Functional Properties of Two Structurally Different D2 Dopamine Receptor Subtype Selective Compounds
  12. Neurosteroid Analog Photolabeling of a Site in the Third Transmembrane Domain of the β3 Subunit of the GABAA Receptor
  13. Neurosteroid Analogues. 17. Inverted Binding Orientations of Androsterone Enantiomers at the Steroid Potentiation Site on γ-Aminobutyric Acid Type A Receptors
  14. A neurosteroid analogue photolabeling reagent labels the colchicine-binding site on tubulin: A mass spectrometric analysis
  15. Subtype Selectivity of Dopamine Receptor Ligands: Insights from Structure and Ligand-Based Methods
  16. Microfluidic labeling of biomolecules with radiometals for use in nuclear medicine
  17. Docking and 3D-QSAR Studies on Isatin Sulfonamide Analogues as Caspase-3 Inhibitors
  18. Synthesis and characterization of the copper(ii) complexes of new N2S2-donor macrocyclic ligands: synthesis and in vivo evaluation of the64Cu complexes
  19. [18F]- and [11C]-Labeled N-benzyl-isatin sulfonamide analogues as PET tracers for Apoptosis: synthesis, radiolabeling mechanism, and in vivo imaging study of apoptosis in Fas-treated mice using [11C]WC-98
  20. Mutations of the GABA-A Receptor α1 Subunit M1 Domain Reveal Unexpected Complexity for Modulation by Neuroactive Steroids
  21. Mechanisms of potentiation of the mammalian GABAAreceptor by the marine cembranoid eupalmerin acetate
  22. CoMSIA and docking study of rhenium based estrogen receptor ligand analogs
  23. Molecular modeling of hexakis(areneisonitrile)technetium(I), tricarbonyl η5 cyclopentadienyl technetium and technetium(V)-oxo complexes: MM3 parameter development and prediction of biological properties
  24. N-Benzylisatin Sulfonamide Analogues as Potent Caspase-3 Inhibitors:  Synthesis, in Vitro Activity, and Molecular Modeling Studies
  25. QSAR Studies of Copper Azamacrocycles and Thiosemicarbazones:  MM3 Parameter Development and Prediction of Biological Properties
  26. Comparative in Vivo Behavior Studies of Cyclen-Based Copper-64 Complexes:  Regioselective Synthesis, X-ray Structure, Radiochemistry, logP, and Biodistribution
  27. Quantitation and visualization of tumor-specific T cells in the secondary lymphoid organs during and after tumor elimination by PET
  28. Use of binding energy in comparative molecular field analysis of isoform selective estrogen receptor ligands
  29. Preparation of 66Ga- and 68Ga-labeled Ga(III)-deferoxamine-folate as potential folate-receptor-targeted PET radiopharmaceuticals
  30. Regioselective N-substitution of cyclen with two different alkyl groups: synthesis of all possible isomersElectronic supplementary information (ESI) available: spectroscopic data. See http://www.rsc.org/suppdata/cc/b2/b212667b/
  31. Production and purification of gallium-66 for preparation of tumor-targeting radiopharmaceuticals
  32. Supramolecular polymer chemistry: design, synthesis, characterization, and kinetics, thermodynamics, and fidelity of formation of self-assembled dendrimers
  33. Molecular Modeling of Bifunctional Chelate Peptide Conjugates. 1. Copper and Indium Parameters for the AMBER Force Field
  34. β-Cyclodextrin dimers as potential tumor pretargeting agents
  35. Labeling and in vivo evaluation of novel copper(II) dioxotetraazamacrocyclic complexes
  36. Synthesis and Characterization of Racemic Mixture and Meso Isomers of Bis(trans-2-aminocyclohexyl)aminepentaacetic Acid and the Stabilities of Their Gd(III) Complexes
  37. Evaluation of gallium-68 tris(2-mercaptobenzyl)amine: a complex with brain and myocardial uptake
  38. Indium(III) and Gallium(III) Complexes of Bis(aminoethanethiol) Ligands with Different Denticities:  Stabilities, Molecular Modeling, andin VivoBehavior
  39. Indium(III) and Gallium(III) Complexes of Bis(aminoethanethiol) Ligands with Different Denticities:  Stabilities, Molecular Modeling, andin VivoBehavior
  40. Molecular Mechanics Investigation of Gadolinium(III) Complexes
  41. Stability and Structure of Activated Macrocycles. Ligands with Biological Applications
  42. Molecular Mechanics Force Field for Modeling Technetium(V) Complexes
  43. Synthesis and structure of molecular tweezers containing active site functionality
  44. Thiophenol promoted cyclization of enynes