All Stories

  1. Evolution and Epidemiology of Multidrug-Resistant Klebsiella pneumoniae in the United Kingdom and Ireland
  2. Evaluation of an Optimal Epidemiological Typing Scheme for Legionella pneumophila with Whole-Genome Sequence Data Using Validation Guidelines
  3. Genomic perspectives on the evolution and spread of bacterial pathogens
  4. Implications of multiple freeze-thawing on respiratory samples for culture-independent analyses
  5. Complete Genome Sequence of Bordetella pertussis D420
  6. Emergent and evolving antimicrobial resistance cassettes in community-associated fusidic acid and meticillin-resistant Staphylococcus aureus
  7. Large-scale whole genome sequencing ofM. tuberculosisprovides insights into transmission in a high prevalence area
  8. Staphylococcus aureus Adapts to Oxidative Stress by Producing H2O2-Resistant Small-Colony Variants via the SOS Response
  9. Microbiota That Affect Risk for Shigellosis in Children in Low-Income Countries
  10. Erratum: Corrigendum: Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline
  11. Genome specialization and decay of the strangles pathogen, Streptococcus equi, is driven by persistent infection
  12. Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting
  13. Whole-Genome Sequencing Confirms that Burkholderia pseudomallei Multilocus Sequence Types Common to Both Cambodia and Australia Are Due to Homoplasy
  14. Reagent and laboratory contamination can critically impact sequence-based microbiome analyses
  15. The extant World War 1 dysentery bacillus NCTC1: a genomic analysis
  16. Bacillary dysentery from World War 1 and NCTC1, the first bacterial isolate in the National Collection
  17. Recurrence due to Relapse or Reinfection WithMycobacterium tuberculosis: A Whole-Genome Sequencing Approach in a Large, Population-Based Cohort With a High HIV Infection Prevalence and Active Follow-up
  18. Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles
  19. Defining the Estimated Core Genome of Bacterial Populations Using a Bayesian Decision Model
  20. Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis
  21. Comprehensive Identification of Single Nucleotide Polymorphisms Associated with Beta-lactam Resistance within Pneumococcal Mosaic Genes
  22. Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains
  23. Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline
  24. Reagent contamination can critically impact sequence-based microbiome analyses
  25. An integrated catalog of reference genes in the human gut microbiome
  26. Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
  27. PolyTB: A genomic variation map for Mycobacterium tuberculosis
  28. Cryptic ecology among host generalistCampylobacter jejuniin domestic animals
  29. Global Population Structure and Evolution of Bordetella pertussis and Their Relationship with Vaccination
  30. Comment on: Characterization of the embB gene in Mycobacterium tuberculosis isolates from Barcelona and rapid detection of main mutations related to ethambutol resistance using a low-density DNA array
  31. Genomic epidemiology of Neisseria gonorrhoeae with reduced susceptibility to cefixime in the USA: a retrospective observational study
  32. The Impact of Different DNA Extraction Kits and Laboratories upon the Assessment of Human Gut Microbiota Composition by 16S rRNA Gene Sequencing
  33. Dense genomic sampling identifies highways of pneumococcal recombination
  34. Evolution and transmission of drug-resistant tuberculosis in a Russian population
  35. Comparative genome analysis of Wolbachia strain wAu
  36. Genomic Epidemiology of Vibrio cholerae O1 Associated with Floods, Pakistan, 2010
  37. Variable recombination dynamics during the emergence, transmission and ‘disarming’ of a multidrug-resistant pneumococcal clone
  38. Diarrhea in young children from low-income countries leads to large-scale alterations in intestinal microbiota composition
  39. The hospital microbiome project: meeting report for the UK science and innovation network UK-USA workshop ‘beating the superbugs: hospital microbiome studies for tackling antimicrobial resistance’, October 14th 2013
  40. Correction: Expression of Cellulosome Components and Type IV Pili within the Extracellular Proteome of Ruminococcus flavefaciens 007
  41. Elucidating Emergence and Transmission of Multidrug-Resistant Tuberculosis in Treatment Experienced Patients by Whole Genome Sequencing
  42. Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study
  43. Generating whole bacterial genome sequences of low-abundance species from complex samples with IMS-MDA
  44. Transcriptional Regulation of Culex pipiens Mosquitoes by Wolbachia Influences Cytoplasmic Incompatibility
  45. Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection
  46. Patent Human Infections with the Whipworm, Trichuris trichiura, Are Not Associated with Alterations in the Faecal Microbiota
  47. The Distribution and ‘In Vivo’ Phase Variation Status of Haemoglobin Receptors in Invasive Meningococcal Serogroup B Disease: Genotypic and Phenotypic Analysis
  48. A Study on the Geophylogeny of Clinical and Environmental Vibrio cholerae in Kenya
  49. Fighting Obesity with Bacteria
  50. Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans
  51. What has high-throughput sequencing ever done for us?
  52. Rapid Bacterial Whole-Genome Sequencing to Enhance Diagnostic and Public Health Microbiology
  53. Transmission of M abscessus in patients with cystic fibrosis – Authors' reply
  54. Richness of human gut microbiome correlates with metabolic markers
  55. Whole-Genome Sequencing for Rapid Susceptibility Testing of M. tuberculosis
  56. Incidence and Characterisation of Methicillin-Resistant Staphylococcus aureus (MRSA) from Nasal Colonisation in Participants Attending a Cattle Veterinary Conference in the UK
  57. Read and assembly metrics inconsequential for clinical utility of whole-genome sequencing in mapping outbreaks
  58. Consequences ofwhiB7(Rv3197A) Mutations in Beijing Genotype Isolates of the Mycobacterium tuberculosis Complex
  59. Expression of Cellulosome Components and Type IV Pili within the Extracellular Proteome of Ruminococcus flavefaciens 007
  60. Unusual features in organisation of capsular polysaccharide-related genes of C. jejuni strain X
  61. Novel Mycobacterium tuberculosis Complex Isolate from a Wild Chimpanzee
  62. Population genomics of post-vaccine changes in pneumococcal epidemiology
  63. Whole-genome sequencing to identify transmission of Mycobacterium abscessus between patients with cystic fibrosis: a retrospective cohort study
  64. Comprehensive Assignment of Roles for Salmonella Typhimurium Genes in Intestinal Colonization of Food-Producing Animals
  65. Description and Nomenclature of Neisseria meningitidis Capsule Locus
  66. Whole genome sequencing identifies zoonotic transmission of MRSA isolates with the novel mecA homologue mecC
  67. Inferring patient to patient transmission of Mycobacterium tuberculosisfrom whole genome sequencing data
  68. Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions
  69. Transcription factor T-bet regulates intestinal inflammation mediated by innate lymphoid cells with the interleukin-7 receptor
  70. Whole-genome sequencing for analysis of an outbreak of meticillin-resistant Staphylococcus aureus: a descriptive study
  71. Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study
  72. Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis
  73. Evidence of antimicrobial resistance-conferring genetic elements among pneumococci isolated prior to 1974
  74. Progressive genome‐wide introgression in agriculturalCampylobacter coli
  75. Emergence and global spread of epidemic healthcare-associated Clostridium difficile
  76. Rapid Whole-Genome Sequencing for Investigation of a Suspected Tuberculosis Outbreak
  77. A whole-genome sequencing approach to targeting Mycobacterium tuberculosis outbreak management
  78. Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice
  79. The Transcription Factor T-bet Regulates Intestinal Inflammation Mediated by Interleukin-7 Receptor+ Innate Lymphoid Cells
  80. Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa
  81. SpolPred: rapid and accurate prediction of Mycobacterium tuberculosis spoligotypes from short genomic sequences
  82. Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach
  83. A small predatory core genome in the divergent marine Bacteriovorax marinus SJ and the terrestrial Bdellovibrio bacteriovorus
  84. Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe
  85. Routine Use of Microbial Whole Genome Sequencing in Diagnostic and Public Health Microbiology
  86. Fibrinogen‐binding and platelet‐aggregation activities of a Lactobacillus salivarius septicaemia isolate are mediated by a novel fibrinogen‐binding protein
  87. A High-Resolution View of Genome-Wide Pneumococcal Transformation
  88. Rapid Whole-Genome Sequencing for Investigation of a Neonatal MRSA Outbreak
  89. Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing
  90. Lineage-specific Virulence Determinants of Haemophilus influenzae Biogroup aegyptius
  91. The Genome of Mycobacterium Africanum West African 2 Reveals a Lineage-Specific Locus and Genome Erosion Common to the M. tuberculosis Complex
  92. Microevolution of extensively drug-resistant tuberculosis in Russia
  93. BamView: visualizing and interpretation of next-generation sequencing read alignments
  94. Phylogeographic variation in recombination rates within a global clone of methicillin-resistant Staphylococcus aureus
  95. Phenotypic and Genomic Analysis of Hypervirulent Human-associated Bordetella bronchiseptica
  96. Investigations into genome diversity of Haemophilus influenzae using whole genome sequencing of clinical isolates and laboratory transformants
  97. The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success
  98. Comparative genomics of the classical Bordetella subspecies: the evolution and exchange of virulence-associated diversity amongst closely related pathogens
  99. Comparative genomics of Brachyspira pilosicoli strains: genome rearrangements, reductions and correlation of genetic compliment with phenotypic diversity
  100. Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data
  101. Sequence-Based Analysis Uncovers an Abundance of Non-Coding RNA in the Total Transcriptome of Mycobacterium tuberculosis
  102. Ileal Pouch Microbial Diversity
  103. Evidence for several waves of global transmission in the seventh cholera pandemic
  104. Salmonella bongori Provides Insights into the Evolution of the Salmonellae
  105. Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study
  106. Emergence of a Globally Dominant IncHI1 Plasmid Type Associated with Multiple Drug Resistant Typhoid
  107. The Impact of Recombination on dN/dS within Recently Emerged Bacterial Clones
  108. Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors
  109. Enterotypes of the human gut microbiome
  110. GSC 11: Julian Parkhill
  111. Citrobacter rodentium is an Unstable Pathogen Showing Evidence of Significant Genomic Flux
  112. Identification, variation and transcription of pneumococcal repeat sequences
  113. Bacterial epidemiology and biology - lessons from genome sequencing
  114. High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease
  115. Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communities
  116. Independent evolution of the core and accessory gene sets in the genus Neisseria: insights gained from the genome of Neisseria lactamica isolate 020-06
  117. Comparative genomics of prevaccination and modern Bordetella pertussis strains
  118. The Genome of a Pathogenic Rhodococcus: Cooptive Virulence Underpinned by Key Gene Acquisitions
  119. Dominant and diet-responsive groups of bacteria within the human colonic microbiota
  120. Emergence of the Asian 1 Genotype of Dengue Virus Serotype 2 in Viet Nam: In Vivo Fitness Advantage and Lineage Replacement in South-East Asia
  121. In-depth genetic analysis ofClostridiumdifficilePCR-ribotype 027 strains reveals high genome fluidity including point mutations and inversions
  122. The Bacteriology of Pouchitis
  123. High-throughput bacterial SNP typing identifies distinct clusters of SalmonellaTyphi causing typhoid in Nepalese children
  124. A human gut microbial gene catalogue established by metagenomic sequencing
  125. Complete Genome Sequence and Comparative Metabolic Profiling of the Prototypical Enteroaggregative Escherichia coli Strain 042
  126. BamView: viewing mapped read alignment data in the context of the reference sequence
  127. Genomic information infrastructure after the deluge
  128. Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen
  129. Distribution of Tetracycline and Erythromycin Resistance Genes Among Human Oral and Fecal Metagenomic DNA
  130. A Strand-Specific RNA–Seq Analysis of the Transcriptome of the Typhoid Bacillus Salmonella Typhi
  131. Rapid Evolution of Virulence and Drug Resistance in the Emerging Zoonotic Pathogen Streptococcus suis
  132. The genome of the blood fluke Schistosoma mansoni
  133. Detecting SNPs and estimating allele frequencies in clonal bacterial populations by sequencing pooled DNA
  134. Genome flexibility in Neisseria meningitidis
  135. Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens
  136. Evolutionary diversification of an ancient gene family (rhs) through C-terminal displacement
  137. Pseudogene accumulation in the evolutionary histories of Salmonella enterica serovars Paratyphi A and Typhi
  138. Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium
  139. Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis
  140. Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens
  141. Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain
  142. Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens
  143. A novel streptococcal integrative conjugative element involved in iron acquisition
  144. DNAPlotter: circular and linear interactive genome visualization
  145. Time to remove the model organism blinkers
  146. Artemis and ACT: viewing, annotating and comparing sequences stored in a relational database
  147. Population genomics: modeling the new and a renaissance of the old
  148. Correction: A Common Genomic Framework for a Diverse Assembly of Plasmids in the Symbiotic Nitrogen Fixing Bacteria
  149. Correction: A Common Genomic Framework for a Diverse Assembly of Plasmids in the Symbiotic Nitrogen Fixing Bacteria
  150. High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi
  151. A Common Genomic Framework for a Diverse Assembly of Plasmids in the Symbiotic Nitrogen Fixing Bacteria
  152. Replacement of Adenylate Cyclase Toxin in a Lineage of Bordetella bronchiseptica
  153. Microbiology in the post-genomic era
  154. Pathogenomics: An updated European Research Agenda
  155. The minimum information about a genome sequence (MIGS) specification
  156. Single-cell genomics
  157. Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis
  158. Resolving the structural features of genomic islands: A machine learning approach
  159. Faculty Opinions recommendation of Genome-wide experimental determination of barriers to horizontal gene transfer.
  160. The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay
  161. The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants
  162. Whole-genome analysis of pathogen evolution
  163. Faculty Opinions recommendation of Temporal fragmentation of speciation in bacteria.
  164. Salmonella enterica Serovar Typhimurium Exploits Inflammation to Compete with the Intestinal Microbiota
  165. Sequence-based analysis of pQBR103; a representative of a unique, transfer-proficient mega plasmid resident in the microbial community of sugar beet
  166. Faculty Opinions recommendation of CRISPR provides acquired resistance against viruses in prokaryotes.
  167. Faculty Opinions recommendation of Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing.
  168. Genetic flux over time in the Salmonella lineage
  169. A Novel Linear Plasmid Mediates Flagellar Variation in Salmonella Typhi
  170. Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome sequence
  171. Ankyrin repeat domain-encoding genes in the wPip strain of Wolbachia from the Culex pipiens group
  172. Meningococcal Genetic Variation Mechanisms Viewed through Comparative Analysis of Serogroup C Strain FAM18
  173. A bimodal pattern of relatedness between the Salmonella Paratyphi A and Typhi genomes: Convergence or divergence by homologous recombination?
  174. Proteomic and microarray characterization of the AggR regulon identifies a pheU pathogenicity island in enteroaggregative Escherichia coli
  175. Faculty Opinions recommendation of A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action.
  176. Interpolated variable order motifs for identification of horizontally acquired DNA: revisiting the Salmonella pathogenicity islands
  177. The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome
  178. Phylogenetic Relationships of the Wolbachia of Nematodes and Arthropods
  179. Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes
  180. The Complete Genome Sequence and Comparative Genome Analysis of the High Pathogenicity Yersinia enterocolitica Strain 8081
  181. Faculty Opinions recommendation of Ancient origin and gene mosaicism of the progenitor of Mycobacterium tuberculosis.
  182. The pCoo Plasmid of Enterotoxigenic Escherichia coli Is a Mosaic Cointegrate
  183. Bacterial pathogens of man
  184. Wolbachia variability and host effects on crossing type in Culex mosquitoes
  185. Identification of DNA Markers for a TransmissiblePseudomonas aeruginosaCystic Fibrosis Strain
  186. ACT: the Artemis comparison tool
  187. Comparative Apicomplexan genomics
  188. Integration of tools and resources for display and analysis of genomic data for protozoan parasites
  189. Faculty Opinions recommendation of Serendipitous discovery of Wolbachia genomes in multiple Drosophila species.
  190. Livelihood hazards
  191. Diversity at every level
  192. Faculty Opinions recommendation of Psi-Phi: exploring the outer limits of bacterial pseudogenes.
  193. Brothers in arms
  194. Enemies within
  195. Comparative genomic view of mechanisms of variation in Neisseria meningitidis through sequencing and analysis of a third meningococcal genome from serogroup C strain FAM18
  196. Comparative Genomic Structure of Prokaryotes
  197. Genomic pot pourri
  198. Eukaryotes: not beyond compare
  199. The complete nucleotide sequence of the resistance plasmid R478: defining the backbone components of incompatibility group H conjugative plasmids through comparative genomics
  200. Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses
  201. Pathogens in decay
  202. The use of genome annotation data and its impact on biological conclusions
  203. Genomes beyond compare
  204. Tyrosine site-specific recombinases mediate DNA inversions affecting the expression of outer surface proteins of Bacteroides fragilis
  205. New environments, versatile genomes
  206. The Role of Prophage-like Elements in the Diversity of Salmonella enterica Serovars
  207. The Bordetellae: lessons from genomics
  208. Strength in diversity
  209. Comparative cell wall core biosynthesis in the mycolated pathogens, Mycobacterium tuberculosis and Corynebacterium diphtheriae
  210. Faculty Opinions recommendation of Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements.
  211. Bacterial minimalism
  212. Faculty Opinions recommendation of Community structure and metabolism through reconstruction of microbial genomes from the environment.
  213. Sequencing the environment
  214. Pathogenomics of non-pathogens
  215. Cobalamin Synthesis in Yersinia enterocolitica 8081
  216. Shrinking genomics
  217. Pathogenomics
  218. Fitting the niche by genomic adaptation
  219. The value of comparison
  220. Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica
  221. A bad combination
  222. The devil is in the detail
  223. Relative pathogenic values
  224. The good, the bad and the ugly?
  225. All walks of life
  226. A matter of fitness
  227. Faculty Opinions recommendation of Unravelling the biology of macrophage infection by gene expression profiling of intracellular Salmonella enterica.
  228. The building blocks of pathogenicity
  229. Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei
  230. The magnificent seven
  231. Spot the difference…
  232. Genome Analysis of an Inducible Prophage and Prophage Remnants Integrated in the Streptococcus pyogenes Strain SF370
  233. Sibling rivalry
  234. Genome giants
  235. Tales of the unexpected
  236. Restricting genome data won't stop bioterrorism
  237. The importance of complete genome sequences
  238. Characterisation and distribution of a cryptic Salmonella typhi plasmid pHCM2
  239. Armed to the teeth
  240. Split personalities
  241. Unlocking the genome of the human typhoid bacillus
  242. Annotation of microbial genomes
  243. Faculty Opinions recommendation of Does blood of healthy subjects contain bacterial ribosomal DNA?
  244. Dynamic duos
  245. Lost and found
  246. Faculty Opinions recommendation of A proteomic view on genome-based signal peptide predictions.
  247. Back in the limelight
  248. The Full Monty
  249. Size matters?
  250. Of staphs, streps and other things
  251. The failure of different strains of Yersinia pestis to produce lipopolysaccharide O-antigen under different growth conditions is due to mutations in the O-antigen gene cluster
  252. Genomics of Mycobacterium bovis
  253. Artemis: sequence visualization and annotation
  254. 'Going wrong with confidence': misleading sequence analyses of CiaB and ClpX
  255. New insertion sequences and a novel repeated sequence in the genome of Mycobacterium tuberculosis H37Rv
  256. Definition of a major p53 binding site on Ad2E1B58K protein and a possible nuclear localization signal on the Ad12E1B54K protein
  257. Selection and characterization of mercury- independent activation mutants of the Tn501 transcriptional regulator, MerR
  258. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
  259. Homology between a human apoptosis specific protein and the product of APG5 , a gene involved in autophagy in yeast
  260. Accelerated telomere shortening in ataxia telangiectasia
  261. Induction of bacterial mercury- and copper-responsive promoters: Functional differences between inducible systems and implications for their use in gene-fusions for in vivo metal biosensors
  262. Induction of the mer operon of Tn501 by the MerR repressor/activator.
  263. Metal homeostasis in Escherichia coli: The regulation of bacterial gene expression by cupric and mercuric ions.
  264. Bacterial resistances to mercury and copper
  265. Site-specific insertion and deletion mutants in the mer promoter-operator region of Tn 501 ; the nineteen base-pair spacer is essential for normal induction of the promoter by MerR
  266. Electronic Access to Mycobacterium tuberculosis Sequence Data
  267. 2 Bacterial Human Pathogen Genomes: an Overview
  268. The Significance of the CtBP — AdE1A Interaction during Viral Infection and Transformation