All Stories

  1. Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells

    Article • Drug Design Development and Therapy, October 2015, Dove Medical Press

    Dr Shuting Pan, Dr zhiwei zhou

  2. Novel targeting of PEGylated liposomes for codelivery of TGF-β1 siRNA and four antitubercular drugs to human macrophages for the treatment of mycobacterial infection: a quantitative proteomic study

    Article • Drug Design Development and Therapy, August 2015, Dove Medical Press

    Dr zhiwei zhou

  3. High-throughput sequencing of 16S rDNA amplicons characterizes bacterial composition in cerebrospinal fluid samples from patients with purulent meningitis

    Article • Drug Design Development and Therapy, August 2015, Dove Medical Press

    Dr zhiwei zhou

  4. High-throughput sequencing of 16S rDNA amplicons characterizes bacterial composition in bronchoalveolar lavage fluid in patients with ventilator-associated pneumonia

    Article • Drug Design Development and Therapy, August 2015, Dove Medical Press

    Dr zhiwei zhou

  5. Controllable drug uptake and nongenomic response through estrogen-anchored cyclodextrin drug complex

    Article • International Journal of Nanomedicine, July 2015, Dove Medical Press

    Dr zhiwei zhou, Dr Shuting Pan

  6. A bioinformatic and mechanistic study elicits the antifibrotic effect of ursolic acid through the attenuation of oxidative stress with the involvement of ERK, PI3K/Akt, and p38 MAPK signaling pathways in human hepatic stellate cells and rat liver

    Article • Drug Design Development and Therapy, July 2015, Dove Medical Press

    Dr zhiwei zhou

  7. Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity

    Article • Drug Design Development and Therapy, April 2015, Taylor & Francis

    Mr Yi Zhang, Dr zhiwei zhou, Professor Si-Yuan Pan

  8. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer A...

    Article • Drug Design Development and Therapy, March 2015, Taylor & Francis

    Dr zhiwei zhou, Professor Si-Yuan Pan

  9. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway

    Article • Drug Design Development and Therapy, March 2015, Taylor & Francis

    Dr zhiwei zhou, Dr Shuting Pan

  10. Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells

    Article • Drug Design Development and Therapy, March 2015, Taylor & Francis

    Dr zhiwei zhou, Dr Shuting Pan

  11. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells

    Article • Drug Design Development and Therapy, March 2015, Taylor & Francis

    Dr zhiwei zhou, Dr Shuting Pan

  12. Estimation of the binding modes with important human cytochrome P450 enzymes, drug interaction potential, pharmacokinetics, and hepatotoxicity of ginger components using molecular docking, computational, and pharmacokinetic modeling studies

    Article • Drug Design Development and Therapy, February 2015, Taylor & Francis

    Dr zhiwei zhou

  13. The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells

    Article • Drug Design Development and Therapy, February 2015, Taylor & Francis

    Professor Si-Yuan Pan, Dr zhiwei zhou, Dr Shuting Pan

  14. Proteomic response to 5,6-dimethylxanthenone 4-acetic acid (DMXAA, vadimezan) in human non-small cell lung cancer A549 cells determined by the stable-isotope labeling by amino acids in cell culture (SILAC) approach

    Article • Drug Design Development and Therapy, February 2015, Taylor & Francis

    Dr zhiwei zhou, Dr Shuting Pan

  15. A computational and functional study elicits the ameliorating effect of the Chinese herbal formula Huo Luo Xiao Ling Dan on experimental ischemia-induced myocardial injury in rats via inhibition of apoptosis

    Article • Drug Design Development and Therapy, February 2015, Taylor & Francis

    Dr zhiwei zhou

  16. Hsa-microRNA-181a is a regulator of a number of cancer genes and a biomarker for endometrial carcinoma in patients: a bioinformatic and clinical study and the therapeutic implication

    Article • Drug Design Development and Therapy, February 2015, Taylor & Francis

    Dr zhiwei zhou

  17. Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells

    Article • Drug Design Development and Therapy, January 2015, Taylor & Francis

    Dr zhiwei zhou, Dr Ruan Jin Zhai

  18. Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells

    Article • Drug Design Development and Therapy, January 2015, Taylor & Francis

    Dr zhiwei zhou, Dr Shuting Pan

  19. Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells

    Article • Drug Design Development and Therapy, January 2015, Taylor & Francis

    Dr zhiwei zhou, Dr Shuting Pan

  20. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells

    Article • Drug Design Development and Therapy, January 2015, Taylor & Francis

    Dr zhiwei zhou, Dr Shuting Pan

  21. Xyloketal B, a marine compound, acts on a network of molecular proteins and regulates the activity and expression of rat cytochrome P450 3a: a bioinformatic and animal study

    Article • Drug Design Development and Therapy, December 2014, Taylor & Francis

    Dr zhiwei zhou

  22. Schisandra chinensis regulates drug metabolizing enzymes and drug transporters via activation of Nrf2-mediated signaling pathway

    Article • Drug Design Development and Therapy, December 2014, Taylor & Francis

    Dr zhiwei zhou, Dr Yang Yu

  23. An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides

    Article • Drug Design Development and Therapy, December 2014, Taylor & Francis

    Dr zhiwei zhou, Dr Ruan Jin Zhai

  24. Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells

    Article • Drug Design Development and Therapy, December 2014, Dove Medical Press

    Dr zhiwei zhou