All Stories

  1. Inhibition of choline metabolism in an angioimmunoblastic T-cell lymphoma preclinical model reveals a new metabolic vulnerability as possible target for treatment

    Article • Journal of Experimental & Clinical Cancer Research, February 2024, Springer Science + Business Media

    Dr Marie Tosolini

  2. IL-27 maintains cytotoxic Ly6C+ gamma delta T cells that arise from immature precursors

    Article • October 2023, Cold Spring Harbor Laboratory Press

    Dr Marie Tosolini

  3. TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation

    Article • Immunity, July 2023, Elsevier

    Dr Marie Tosolini

  4. The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation

    Article • Cell Reports, March 2023, Elsevier

    Dr Marie Tosolini

  5. Single-cell spatial explorer: easy exploration of spatial and multimodal transcriptomics

    Article • BMC Bioinformatics, January 2023, Springer Science + Business Media

    Dr Marie Tosolini

  6. Histological Subtypes Drive Distinct Prognostic Immune Signatures in Classical Hodgkin Lymphoma

    Article • Cancers, October 2022, MDPI AG

    Dr Marie Tosolini

  7. Single-cell Spatial Explorer: Easy exploration of spatial and multimodal transcriptomics

    Article • August 2022, Cold Spring Harbor Laboratory Press

    Dr Marie Tosolini

  8. Single-Cell RNAseq Profiling of Human γδ T Lymphocytes in Virus-Related Cancers and COVID-19 Disease

    Article • Viruses, November 2021, MDPI AG

    Dr Marie Tosolini

  9. Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia

    Article • Nature Cancer, November 2021, Springer Science + Business Media

    Dr Marie Tosolini

  10. Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component

    Article • EMBO Molecular Medicine, May 2021, EMBO

    Dr Marie Tosolini

  11. Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy

    Article • Cancer Immunology Research, March 2021, American Association for Cancer Research (AACR)

    Dr Marie Tosolini

  12. Lymphoma Heterogeneity Unraveled by Single-Cell Transcriptomics

    Article • Frontiers in Immunology, February 2021, Frontiers

    Dr Marie Tosolini

  13. Phased differentiation of γδ T and T CD8 tumor-infiltrating lymphocytes revealed by single-cell transcriptomics of human cancers

    Article • OncoImmunology, January 2021, Taylor & Francis

    Dr Marie Tosolini

  14. Baseline SUVmax is related to tumor cell proliferation and patient outcome in follicular lymphoma

    Article • Haematologica, December 2020, Ferrata Storti Foundation (Haematologica)

    Dr Marie Tosolini

  15. PD-1 blockade restores helper activity of tumor-infiltrating exhausted PD-1hiCD39+ CD4 T cells

    Article • JCI Insight, December 2020, American Society for Clinical Investigation

    Dr Marie Tosolini

  16. Longitudinal CITE-Seq profiling of chronic lymphocytic leukemia during ibrutinib treatment: evolution of leukemic and immune cells at relapse

    Article • Biomarker Research, December 2020, Springer Science + Business Media

    Dr Marie Tosolini

  17. ALK-transformed mature T lymphocytes restore early thymus progenitor features

    Article • Journal of Clinical Investigation, November 2020, American Society for Clinical Investigation

    Dr Marie Tosolini

  18. Ly6C defines a subset of memory-like CD27+ γδ T cells with inducible cancer-killing function

    Article • September 2020, Cold Spring Harbor Laboratory Press

    Dr Marie Tosolini

  19. Single-Cell Virtual Cytometer allows user-friendly and versatile analysis and visualization of multimodal single cell RNAseq datasets

    Article • NAR Genomics and Bioinformatics, April 2020, Oxford University Press (OUP)

    Dr Marie Tosolini

  20. Dual Relief of T-Lymphocyte Proliferation and Effector Function Underlies Response to PD-1 Blockade in Epithelial Malignancies

    Article • Cancer Immunology Research, April 2020, American Association for Cancer Research (AACR)

    Dr Marie Tosolini

  21. Colon-specific immune microenvironment regulates cancer progression versus rejection

    Article • OncoImmunology, January 2020, Taylor & Francis

    Dr Marie Tosolini

  22. Single-Cell Virtual Cytometer allows user-friendly and versatile analysis and visualization of multimodal single cell RNAseq datasets

    Article • November 2019, Cold Spring Harbor Laboratory Press

    Dr Marie Tosolini

  23. Ionizing radiation induces endothelial transdifferentiation of glioblastoma stem-like cells through the Tie2 signaling pathway

    Article • Cell Death and Disease, October 2019, Springer Science + Business Media

    Dr Marie Tosolini

  24. MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors

    Article • Cell Reports, September 2019, Elsevier

    Dr Marie Tosolini

  25. GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism

    Article • Cancer Cell, September 2019, Elsevier

    Dr Marie Tosolini

  26. A Tridimensional Model for NK Cell-Mediated ADCC of Follicular Lymphoma

    Article • Frontiers in Immunology, August 2019, Frontiers

    Dr Marie Tosolini

  27. Single-Cell Signature Explorer for comprehensive visualization of single cell signatures across scRNA-seq datasets

    Article • Nucleic Acids Research, July 2019, Oxford University Press (OUP)

    Dr Marie Tosolini

  28. Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRVδ1 and TCRVδ2 γδ T lymphocytes

    Article • Proceedings of the National Academy of Sciences, May 2019, Proceedings of the National Academy of Sciences

    Dr Marie Tosolini

  29. Single-Cell Signature Explorer for comprehensive visualization of single cell signatures across scRNA-seq data sets

    Article • April 2019, Cold Spring Harbor Laboratory Press

    Dr Marie Tosolini

  30. PTMselect: optimization of protein modifications discovery by mass spectrometry

    Article • Scientific Reports, March 2019, Springer Science + Business Media

    Dr Marie Tosolini

  31. Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells

    Article • Cell Reports, January 2019, Elsevier

    Dr Marie Tosolini

  32. Inter- and intra-tumoral heterogeneity in cancer-associated fibroblasts of human pancreatic ductal adenocarcinoma

    Article • The Journal of Pathology, December 2018, Wiley

    Dr Marie Tosolini, Dr Jerome Cros

  33. Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma

    Article • OncoImmunology, December 2018, Taylor & Francis

    Dr Marie Tosolini

  34. Profiling Immune Escape in Hodgkin’s and Diffuse large B-Cell Lymphomas Using the Transcriptome and Immunostaining

    Article • Cancers, October 2018, MDPI AG

    Dr Marie Tosolini

  35. RND1 regulates migration of human glioblastoma stem-like cells according to their anatomical localization and defines a prognostic signature in glioblastoma

    Article • Oncotarget, August 2018, Impact Journals, LLC

    Dr Marie Tosolini

  36. Immune profile of plasmablastic lymphoma

    Article • OncoImmunology, July 2018, Taylor & Francis

    Dr Marie Tosolini, Nathalie Van Acker

  37. Dendrogenin A (DDA) is a cholesterol metabolite with potent anticancer properties

    Article • Nature Communications, December 2017, Nature

    Dr Marie Tosolini, Dr Marc Etienne Poirot

  38. Distinctive features of tumor-infiltrating γδ T lymphocytes in human colorectal cancer

    Article • OncoImmunology, July 2017, Taylor & Francis

    Dr Marie Tosolini, Francesco Dieli

  39. Long noncoding RNA expression profile in cytogenetically normal acute myeloid leukemia identifies a distinct signature and a new biomarker in NPM1-mutated patients

    Article • Haematologica, July 2017, Ferrata Storti Foundation (Haematologica)

    Dr Marie Tosolini

  40. Assessment of tumor-infiltrating TCRVγ9Vδ2 γδ lymphocyte abundance by deconvolution of human cancers microarrays

    Article • OncoImmunology, February 2017, Taylor & Francis

    Dr Marie Tosolini

  41. Nurse-like cells promote CLL survival through LFA-3/CD2 interactions

    Article • Oncotarget, November 2016, Impact Journals, LLC

    Dr Marie Tosolini

  42. Large-scale microarray profiling reveals four stages of immune escape in non-Hodgkin lymphomas

    Article • OncoImmunology, May 2016, Taylor & Francis

    Dr Marie Tosolini

  43. The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis

    Article • Science Translational Medicine, February 2016, American Association for the Advancement of Science

    Dr Marie Tosolini

  44. Cyclic dinucleotides modulate human T-cell response through monocyte cell death

    Article • European Journal of Immunology, October 2015, Wiley

    Dr Marie Tosolini

  45. Mechanisms of PD-1/PD-L1 expression and prognostic relevance in non-Hodgkin lymphoma: a summary of immunohistochemical studies

    Article • Oncotarget, July 2015, Impact Journals, LLC

    Dr Marie Tosolini

  46. Several immune escape patterns in non-Hodgkin's lymphomas

    Article • OncoImmunology, April 2015, Taylor & Francis

    Dr Marie Tosolini

  47. The fatal ADORAtion of adenosine based cyclic dinucleotides

    Article • Molecular and Cellular Biology, November 2014, ASM Journals

    Dr Marie Tosolini

  48. Simultaneous growth of two cancer cell lines demonstrates variability in growth rates

    Article • Open Access Medical Statistics, November 2014, Taylor & Francis

    Dr Marie Tosolini

  49. Functional Network Pipeline Reveals Genetic Determinants Associated with in Situ Lymphocyte Proliferation and Survival of Cancer Patients

    Article • Science Translational Medicine, March 2014, American Association for the Advancement of Science

    Dr Marie Tosolini

  50. The impact of cellular senescence and DNA damage on colorectal tumour progression

    Article • Journal for ImmunoTherapy of Cancer, November 2013, BMJ

    Dr Marie Tosolini

  51. Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

    Article • Immunity, October 2013, Elsevier

    Dr Marie Tosolini

  52. nwCompare and AutoCompare Softwares for Proteomics and Transcriptomics Data Mining – Application to the Exploration of Gene Expression Profiles of Aggressive Lymphomas

    Article • February 2012, IntechOpen

    Dr Marie Tosolini

  53. Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

    Article • Cancer Research, February 2011, American Association for Cancer Research (AACR)

    Dr Marie Tosolini

  54. Histopathologic-Based Prognostic Factors of Colorectal Cancers Are Associated With the State of the Local Immune Reaction

    Article • Journal of Clinical Oncology, January 2011, American Society of Clinical Oncology (ASCO)

    Dr Marie Tosolini

  55. Biomolecular Network Reconstruction Identifies T-Cell Homing Factors Associated With Survival in Colorectal Cancer

    Article • Gastroenterology, April 2010, Elsevier

    Dr Marie Tosolini

  56. In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal Cancer

    Article • Journal of Clinical Oncology, October 2009, American Society of Clinical Oncology (ASCO)

    Dr Marie Tosolini

  57. FOXP3-enriched infiltrates associated with better outcome in renal allografts with inflamed fibrosis

    Article • Nephrology Dialysis Transplantation, September 2009, Oxford University Press (OUP)

    Dr Marie Tosolini

  58. Coordination of Intratumoral Immune Reaction and Human Colorectal Cancer Recurrence

    Article • Cancer Research, March 2009, American Association for Cancer Research (AACR)

    Dr Marie Tosolini

  59. ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

    Article • Bioinformatics, February 2009, Oxford University Press (OUP)

    Dr Marie Tosolini

  60. Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

    Article • Science, September 2006, American Association for the Advancement of Science

    Dr Marie Tosolini