All Stories

  1. Third Generation Photo-Cross-Linked Small-Molecule Affinity Matrix: A Photoactivatable and Photocleavable System Enabling Quantitative Analysis of the Photo-Cross-Linked Small Molecules and Their Target Purification

    Article • Bioconjugate Chemistry, March 2015, American Chemical Society (ACS)

    Professor Naoki Kanoh

  2. Irciniastatin A, a pederin-type translation inhibitor, promotes ectodomain shedding of cell-surface tumor necrosis factor receptor 1

    Article • The Journal of Antibiotics, January 2015, Springer Science + Business Media

    Professor Naoki Kanoh

  3. ChemInform Abstract: Total Synthesis of the Proposed Structure of Heronamide C.

    Article • ChemInform, November 2014, Wiley

    Professor Naoki Kanoh

  4. A Concise and Unified Strategy for Synthesis of the C1–C18 Macrolactone Fragments of FD-891, FD-892 and Their Analogues: Formal Total Synthesis of FD-891

    Article • Organic Letters, October 2014, American Chemical Society (ACS)

    Professor Naoki Kanoh

  5. Eu(OTf) 3 -Catalyzed Highly Regioselective Nucleophilic Ring Opening of 2,3-Epoxy Alcohols: An Efficient Entry to 3-Substituted 1,2-Diol Derivatives

    Article • Organic Letters, September 2014, American Chemical Society (ACS)

    Professor Naoki Kanoh

  6. ChemInform Abstract: Enantioselective Intramolecular Aza-Spiroannulation onto Benzofurans Using Chiral Rhodium Catalysis.

    Article • ChemInform, July 2014, Wiley

    Professor Naoki Kanoh

  7. Total Synthesis of the Proposed Structure of Heronamide C

    Article • European Journal of Organic Chemistry, January 2014, Wiley

    Professor Naoki Kanoh

  8. Enantioselective Intramolecular Aza-Spiroannulation onto Benzofurans Using Chiral Rhodium Catalysis

    Article • Heterocycles, January 2014, Japan Institute of Heterocyclic Chemistry

    Professor Naoki Kanoh

  9. On the Origin of cine-Substitution in the Stille Coupling of Trisubstituted Iodoalkene and trans-Vinylstannane

    Article • Synlett, November 2013, Thieme Publishing Group

    Professor Naoki Kanoh

  10. Dual Structure–Activity Relationship of Osteoclastogenesis Inhibitor Methyl Gerfelin Based on TEG Scanning

    Article • Bioconjugate Chemistry, January 2013, American Chemical Society (ACS)

    Professor Naoki Kanoh

  11. An improved fluorogenic NAD(P)+ detection method using 2-acetylbenzofuran: its origin and application

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Professor Naoki Kanoh

  12. Synthesis and Structure-Activity Relationship of Vicenistatin, a Cytotoxic 20-Membered Macrolactam Glycoside

    Article • Chemistry - An Asian Journal, September 2012, Wiley

    Professor Naoki Kanoh

  13. Corrigendum: Detection of Cytochrome P450 Substrates by Using a Small-Molecule Droplet Array on an NADH-Immobilized Solid Surface

    Article • ChemBioChem, December 2011, Wiley

    Professor Naoki Kanoh

  14. Detection of Cytochrome P450 Substrates by Using a Small-Molecule Droplet Array on an NADH-Immobilized Solid Surface

    Article • ChemBioChem, November 2011, Wiley

    Professor Naoki Kanoh

  15. Preparation of Photo-Cross-Linked Small Molecule Affinity Matrices for Affinity Selection of Protein Targets for Biologically Active Small Molecules

    Article • August 2011, Springer Science + Business Media

    Professor Naoki Kanoh

  16. Concise Entry to Both Enantiomers of 8-Oxabicyclo[3.2.1]oct-3-en-2-one Based on Novel Oxidative Etherification: Formal Synthesis of (+)-Sundiversifolide

    Article • Organic Letters, July 2011, American Chemical Society (ACS)

    Professor Naoki Kanoh

  17. Asymmetric Total Synthesis of (−)-Scabronine G via Intramolecular Double Michael Reaction and Prins Cyclization

    Article • Organic Letters, June 2011, American Chemical Society (ACS)

    Professor Naoki Kanoh

  18. ChemInform Abstract: An Enantio- and Diastereocontrolled Synthesis of (-)-Salinosporamide A (X).

    Article • ChemInform, January 2011, Wiley

    Professor Naoki Kanoh

  19. ChemInform Abstract: Organic Chemistry at the Interface of Complex Bioactive Natural Product and Chemical Biology

    Article • ChemInform, January 2011, Wiley

    Professor Naoki Kanoh

  20. Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway

    Article • Toxicology Letters, December 2010, Elsevier

    Professor Naoki Kanoh

  21. Concise Total Synthesis of Vicenistatin

    Article • Synlett, September 2010, Thieme Publishing Group

    Professor Naoki Kanoh

  22. KSRP/FUBP2 Is a Binding Protein of GO-Y086, a Cytotoxic Curcumin Analogue

    Article • ACS Medicinal Chemistry Letters, September 2010, American Chemical Society (ACS)

    Professor Naoki Kanoh

  23. ChemInform Abstract: Syntheses and Biological Evaluation of Irciniastatin A and the C1-C2 Alkyne Analogue.

    Article • ChemInform, June 2010, Wiley

    Professor Naoki Kanoh

  24. ChemInform Abstract: Total Synthesis and Determination of the Absolute Configuration of (-)-Idesolide.

    Article • ChemInform, June 2010, Wiley

    Professor Naoki Kanoh

  25. ChemInform Abstract: Synthetic Studies on Azadirachtin: Construction of the Highly Functionalized Decalin Moiety of Azadirachtin.

    Article • ChemInform, June 2010, Wiley

    Professor Naoki Kanoh

  26. ChemInform Abstract: Total Synthesis of (-)-Penitrem D.

    Article • ChemInform, May 2010, Wiley

    Professor Naoki Kanoh

  27. ChemInform Abstract: Synthetic Studies on Azadirachtin: Asymmetric Synthesis of the Tetracyclic Decalin Part (I) of Azadirachtin.

    Article • ChemInform, May 2010, Wiley

    Professor Naoki Kanoh

  28. ChemInform Abstract: Synthetic Studies on Azadirachtin: An Efficient Asymmetric Synthesis of the Highly Functionalized Tricyclic Decalin Part of Azadirachtin.

    Article • ChemInform, May 2010, Wiley

    Professor Naoki Kanoh

  29. ChemInform Abstract: Synthetic Studies on Altohyrtins (Spongistatins): Synthesis of the C29-C44 (EF) Portion.

    Article • ChemInform, May 2010, Wiley

    Professor Naoki Kanoh

  30. ChemInform Abstract: Highly Enantioselective Intramolecular Aza-Spiroannulation onto Indoles Using Chiral Rhodium Catalysis: Asymmetric Entry to the Spiro-β-lactam Core of Chartellines.

    Article • ChemInform, March 2010, Wiley

    Professor Naoki Kanoh

  31. Total Synthesis and Determination of the Absolute Configuration of (−)-Idesolide

    Article • Organic Letters, March 2010, American Chemical Society (ACS)

    Professor Naoki Kanoh

  32. Syntheses and Biological Evaluation of Irciniastatin A and the C1−C2 Alkyne Analogue

    Article • Organic Letters, March 2010, American Chemical Society (ACS)

    Professor Naoki Kanoh

  33. Structure–activity relationship of C5-curcuminoids and synthesis of their molecular probes thereof

    Article • Bioorganic & Medicinal Chemistry, February 2010, Elsevier

    Professor Naoki Kanoh

  34. Cleavable Linker for Photo-Cross-Linked Small-Molecule Affinity Matrix

    Article • Bioconjugate Chemistry, January 2010, American Chemical Society (ACS)

    Professor Naoki Kanoh

  35. Construction of Photo-Cross-Linked Microarrays of Small Molecules

    Article • January 2010, Springer Science + Business Media

    Professor Naoki Kanoh

  36. An Enantio- and Diastereocontrolled Synthesis of (–)-Salinosporamide A

    Article • Heterocycles, January 2010, Japan Institute of Heterocyclic Chemistry

    Professor Naoki Kanoh

  37. Organic Chemistry at the Interface of Complex Bioactive Natural Product and Chemical Biology

    Article • Journal of Synthetic Organic Chemistry Japan, January 2010, The Society of Synthetic Organic Chemistry, Japan

    Professor Naoki Kanoh

  38. An Expedient Route to a Potent Gastrin/CCK-B Receptor Antagonist (+)-AG-041R

    Article • The Journal of Organic Chemistry, October 2009, American Chemical Society (ACS)

    Professor Naoki Kanoh

  39. Synthetic Studies on Daphnicyclidin A: Enantiocontrolled Construction of the BCD Ring System

    Article • Organic Letters, April 2009, American Chemical Society (ACS)

    Professor Naoki Kanoh

  40. Structure-Affinity Relationship Study of Bleomycins and ShbleProtein by Use of a Chemical Array

    Article • ChemBioChem, March 2009, Wiley

    Professor Naoki Kanoh

  41. ChemInform Abstract: Efficient Entry to the Pyrroloquinoline Core of Martinella Alkaloids via Novel Base-Catalyzed Mukaiyama-Mannich Reaction.

    Article • ChemInform, February 2009, Wiley

    Professor Naoki Kanoh

  42. Total Synthesis of Methyl Sarcophytoate, a Marine Natural Biscembranoid

    Article • The Journal of Organic Chemistry, January 2009, American Chemical Society (ACS)

    Professor Naoki Kanoh

  43. Syntheses of naturally occurring cytotoxic [7.7]paracyclophanes, (−)-cylindrocyclophane A and its enantiomer, and implications for biological activity

    Article • Organic & Biomolecular Chemistry, January 2009, Royal Society of Chemistry

    Professor Naoki Kanoh

  44. Highly enantioselective intramolecular aza-spiroannulation onto indoles using chiral rhodium catalysis: asymmetric entry to the spiro-β-lactam core of chartellines

    Article • Chemical Communications, January 2009, Royal Society of Chemistry

    Professor Naoki Kanoh

  45. Synthesis and biological activities of reveromycin A and spirofungin A derivatives

    Article • Bioorganic & Medicinal Chemistry Letters, July 2008, Elsevier

    Professor Naoki Kanoh

  46. Distribution of photo-cross-linked products from 3-aryl-3-trifluoromethyldiazirines and alcohols

    Article • Tetrahedron, June 2008, Elsevier

    Professor Naoki Kanoh

  47. Efficient Entry to the Pyrroloquinoline Core of Martinella Alkaloids via Novel Base-catalyzed Mukaiyama–Mannich Reaction

    Article • Chemistry Letters, January 2008, Chemical Society of Japan

    Professor Naoki Kanoh

  48. Total Synthesis of Methyl Sarcophytoate.

    Article • ChemInform, December 2007, Wiley

    Professor Naoki Kanoh

  49. Synthesis of Methyl Sarcophytoate

    Article • Synfacts, December 2007, Thieme Publishing Group

    Professor Naoki Kanoh

  50. Total Synthesis of Methyl Sarcophytoate

    Article • Journal of the American Chemical Society, August 2007, American Chemical Society (ACS)

    Professor Naoki Kanoh

  51. Photo-Cross-Linked Small-Molecule Microarrays as Chemical Genomic Tools for Dissecting Protein–Ligand Interactions

    Article • Chemistry - An Asian Journal, December 2006, Wiley

    Professor Naoki Kanoh

  52. Small-Molecule Microarrays as Tools for Facilitating Chemical Genomics: Recent Advances

    Article • ChemInform, November 2006, Wiley

    Professor Naoki Kanoh

  53. SPR Imaging of Photo-Cross-Linked Small-Molecule Arrays on Gold

    Article • Analytical Chemistry, April 2006, American Chemical Society (ACS)

    Professor Naoki Kanoh

  54. ケミカルゲノミクス研究用ツールとしての低分子有機化合物のマイクロアレイ化技術

    Article • Journal of Synthetic Organic Chemistry Japan, January 2006, The Society of Synthetic Organic Chemistry, Japan

    Professor Naoki Kanoh

  55. Photo-Cross-Linked Small-Molecule Affinity Matrix for Facilitating Forward and Reverse Chemical Genetics

    Article • Angewandte Chemie International Edition, July 2005, Wiley

    Professor Naoki Kanoh

  56. Photo-Cross-Linked Small-Molecule Affinity Matrix for Facilitating Forward and Reverse Chemical Genetics

    Article • Angewandte Chemie International Edition, July 2005, Wiley

    Professor Naoki Kanoh

  57. Photo-Cross-Linked Small-Molecule Affinity Matrix for Facilitating Forward and Reverse Chemical Genetics

    Article • Angewandte Chemie International Edition, June 2005, Wiley

    Professor Naoki Kanoh

  58. Photo-Cross-Linked Small-Molecule Affinity Matrix for Facilitating Forward and Reverse Chemical Genetics

    Article • Angewandte Chemie, June 2005, Wiley

    Professor Naoki Kanoh

  59. Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells

    Article • FEBS Letters, March 2005, Wiley

    Professor Naoki Kanoh

  60. Synthetic studies on biscembranoids: asymmetric total synthesis of methyl sarcoate

    Article • Tetrahedron Letters, February 2005, Elsevier

    Professor Naoki Kanoh

  61. Oxidative Deprotection of 1,3-Dithiane Group Using NaClO2 and NaH2PO4 in Aqueous Methanol.

    Article • ChemInform, January 2005, Wiley

    Professor Naoki Kanoh

  62. The Anticancer Natural Product Pironetin Selectively Targets Lys352 of α-Tubulin

    Article • Chemistry & Biology, June 2004, Elsevier

    Professor Naoki Kanoh

  63. Formal Total Synthesis of Altohyrtin C (I) (Spongistatin 2). Part 1. Aldol Approach to Unite AB (II) and CD (III) Spiroacetals.

    Article • ChemInform, February 2004, Wiley

    Professor Naoki Kanoh

  64. Oxidative Deprotection of 1,3-Dithiane Group Using NaClO 2 and NaH 2 PO 4 in Aqueous Methanol

    Article • Synlett, January 2004, Thieme Publishing Group

    Professor Naoki Kanoh

  65. Immobilization of Natural Products on Glass Slides by Using a Photoaffinity Reaction and the Detection of Protein–Small-Molecule Interactions

    Article • Angewandte Chemie, November 2003, Wiley

    Professor Naoki Kanoh

  66. Immobilization of Natural Products on Glass Slides by Using a Photoaffinity Reaction and the Detection of Protein–Small-Molecule Interactions

    Article • Angewandte Chemie International Edition, November 2003, Wiley

    Professor Naoki Kanoh

  67. Formal total synthesis of altohyrtin C (spongistatin 2). Part 1: Aldol approach to unite AB and CD spiroacetals

    Article • Tetrahedron Letters, October 2003, Elsevier

    Professor Naoki Kanoh

  68. Formal total synthesis of altohyrtin C (spongistatin 2). Part 2: Construction of fully elaborated ABCD and EF fragments

    Article • Tetrahedron Letters, October 2003, Elsevier

    Professor Naoki Kanoh

  69. Tremorgenic Indole Alkaloids. The Total Synthesis of (−)-Penitrem D

    Article • Journal of the American Chemical Society, July 2003, American Chemical Society (ACS)

    Professor Naoki Kanoh

  70. Practical deracemization of NM-3, a synthetic angiogenesis inhibitor

    Article • Tetrahedron Asymmetry, May 2003, Elsevier

    Professor Naoki Kanoh

  71. Studies Aimed at the Total Synthesis of Azadirachtin. A Modeled Connection of C-8 and C-14 in Azadirachtin

    Article • Organic Letters, August 2002, American Chemical Society (ACS)

    Professor Naoki Kanoh

  72. Synthetic studies on altohyrtins (spongistatins): synthesis of the C29–C44 (EF) portion

    Article • Tetrahedron Letters, August 2001, Elsevier

    Professor Naoki Kanoh

  73. Total Synthesis of (−)-Penitrem D

    Article • Journal of the American Chemical Society, November 2000, American Chemical Society (ACS)

    Professor Naoki Kanoh

  74. Synthetic studies on altohyrtins (spongistatins): synthesis of the C15–C28 (CD) spiroacetal portion

    Article • Tetrahedron Letters, April 2000, Elsevier

    Professor Naoki Kanoh

  75. Synthetic Studies on Azadirachtin: Asymmetric Synthesis of the Tetracyclic Decalin Part of Azadirachtin

    Article • Synthesis, January 2000, Thieme Publishing Group

    Professor Naoki Kanoh

  76. Synthetic Studies on Azadirachtin: An Efficient Asymmetric Synthesis of the Highly Functionalized Tricyclic Decalin Part of Azadirachtin

    Article • Synthesis, January 2000, Thieme Publishing Group

    Professor Naoki Kanoh

  77. Tremorgenic Indole Alkaloids. Studies Directed toward the Assembly of the A, F, and I Rings of Penitrem D:  Observation of an Unexpected Stereochemical Outcome

    Article • Organic Letters, October 1999, American Chemical Society (ACS)

    Professor Naoki Kanoh

  78. Synthetic studies on azadirachtin: Construction of the highly functionalized decalin moiety of azadirachtin

    Article • Tetrahedron Letters, June 1999, Elsevier

    Professor Naoki Kanoh

  79. Synthetic Study on Azadirachtin: Asymmetric Synthesis of the Tetracyclic Decalin Part of Azadirachtin

    Article • Synlett, June 1997, Thieme Publishing Group

    Professor Naoki Kanoh

  80. Conversion of prelaureatin into laurallene, a bromo-allene compound, by enzymatic and chemical bromo-etherification reactions

    Article • Tetrahedron, June 1997, Elsevier

    Professor Naoki Kanoh

  81. Construction of the Tricyclic trans-Decalin Framework of Azadirachtins via Intramolecular Diels-Alder Reaction

    Article • Synlett, September 1995, Thieme Publishing Group

    Professor Naoki Kanoh

  82. Enzymatic reaction of (3E,6S,7S)-laurediol and the molecular modeling studies on the cyclization of laurediols

    Article • Tetrahedron Letters, January 1995, Elsevier

    Professor Naoki Kanoh

  83. Isomerization of the (Z)-Enyne Unit to the (E)-Enyne Unit. Conversion of Laureatin to (E)-Isolaureatin.

    Article • Chemistry Letters, January 1994, Chemical Society of Japan

    Professor Naoki Kanoh

  84. Recent Developments and Advances in Chemical Arrays

    Article • Wiley

    Professor Naoki Kanoh