All Stories

  1. JTK-853, a Novel Non-Nucleoside Hepatitis C Virus Polymerase Inhibitor, Demonstrates a High Genetic Barrier to Resistance in vitro

    Article • Intervirology, January 2013, Karger Publishers

    Dr Toru Noguchi

  2. Genotypic and Phenotypic Analyses of Hepatitis C Virus from Patients Treated with JTK-853 in a Three-Day Monotherapy

    Article • Antimicrobial Agents and Chemotherapy, November 2012, ASM Journals

    Dr Toru Noguchi

  3. Preclinical Characterization of JTK-853, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase

    Article • Antimicrobial Agents and Chemotherapy, May 2012, ASM Journals

    Dr Toru Noguchi

  4. Investigation of Interferon-α Response by a Single Amino Acid Substitution of Nonstructural Protein 5A in Hepatitis C Virus-Infected Patients

    Article • Journal of Interferon & Cytokine Research, August 2011, Mary Ann Liebert Inc

    Dr Toru Noguchi

  5. Isolation and gene analysis of interferon α-resistant cell clones of the hepatitis C virus subgenome

    Article • Virology, June 2008, Elsevier

    Dr Toru Noguchi

  6. Effects of Mutation in Hepatitis C Virus Nonstructural Protein 5A on Interferon Resistance Mediated by Inhibition of PKR Kinase Activity in Mammalian Cells

    Article • Microbiology and Immunology, December 2001, Wiley

    Dr Toru Noguchi

  7. Cleavage of Hepatitis C Virus Nonstructural Protein 5A by a Caspase-like Protease(s) in Mammalian Cells

    Article • Virology, May 2000, Elsevier

    Dr Toru Noguchi

  8. Amplification of a DEAD box gene (DDX1) with the MYCN gene in neuroblastomas as a result of cosegregation of sequences flanking the MYCN locus

    Article • Genes Chromosomes and Cancer, February 1996, Wiley

    Dr Toru Noguchi