All Stories

  1. Breadth and Duration of Meningococcal Serum Bactericidal Activity in Health Care Workers and Microbiologists Immunized with the MenB-FHbp Vaccine

    Article • Clinical and Vaccine Immunology, May 2017, ASM Journals

    Dr Dan M Granoff

  2. Serum Bactericidal Antibody Responses of Adults Immunized with the MenB-4C Vaccine against Genetically Diverse Serogroup B Meningococci

    Article • Clinical and Vaccine Immunology, November 2016, ASM Journals

    Dr Dan M Granoff

  3. Impaired Immunogenicity of Meningococcal Neisserial Surface Protein A in Human Complement Factor H Transgenic Mice

    Article • Infection and Immunity, November 2015, ASM Journals

    Dr Dan M Granoff

  4. Susceptibility of Meningococcal Strains Responsible for Two Serogroup B Outbreaks on U.S. University Campuses to Serum Bactericidal Activity Elicited by the MenB-4C Vaccine

    Article • Clinical and Vaccine Immunology, September 2015, ASM Journals

    Dr Dan M Granoff

  5. Functional Analysis of the Human Antibody Response to Meningococcal Factor H Binding Protein

    Article • mBio, June 2015, ASM Journals

    Dr Dan M Granoff

  6. A native outer membrane vesicle vaccine confers protection against meningococcal colonization in human CEACAM1 transgenic mice

    Article • Vaccine, March 2015, Elsevier

    Dr Dan M Granoff

  7. Binding of Complement Factor H to PorB3 and NspA Enhances Resistance of Neisseria meningitidis to Anti-Factor H Binding Protein Bactericidal Activity

    Article • Infection and Immunity, February 2015, ASM Journals

    Dr Dan M Granoff

  8. Heterogeneity in Rhesus Macaque Complement Factor H Binding to Meningococcal Factor H Binding Protein (FHbp) Informs Selection of Primates To Assess Immunogenicity of FHbp-Based Vaccines

    Article • Clinical and Vaccine Immunology, September 2014, ASM Journals

    Dr Dan M Granoff

  9. Human Factor H (FH) Impairs Protective Meningococcal Anti-FHbp Antibody Responses and the Antibodies Enhance FH Binding

    Article • mBio, August 2014, ASM Journals

    Dr Dan M Granoff

  10. Meningococcal factor H-binding protein vaccines with decreased binding to human complement factor H have enhanced immunogenicity in human factor H transgenic mice

    Article • Vaccine, November 2013, Elsevier

    Dr Dan M Granoff

  11. fH-dependent complement evasion by disease-causing meningococcal strains with absent fHbp genes or frameshift mutations

    Article • Vaccine, August 2013, Elsevier

    Dr Dan M Granoff

  12. Mutant Native Outer Membrane Vesicles Combined with a Serogroup A Polysaccharide Conjugate Vaccine for Prevention of Meningococcal Epidemics in Africa

    Article • PLoS ONE, June 2013, PLOS

    Dr Dan M Granoff

  13. Does Binding of Complement Factor H to the Meningococcal Vaccine Antigen, Factor H Binding Protein, Decrease Protective Serum Antibody Responses?

    Article • Clinical and Vaccine Immunology, June 2013, ASM Journals

    Dr Dan M Granoff

  14. Portrait

    Article • Human Vaccines & Immunotherapeutics, May 2013, Taylor & Francis

    Dr Dan M Granoff

  15. The Effect of Human Factor H on Immunogenicity of Meningococcal Native Outer Membrane Vesicle Vaccines with Over-Expressed Factor H Binding Protein

    Article • PLoS Pathogens, May 2012, PLOS

    Dr Dan M Granoff

  16. A Broadly Cross-Reactive Monoclonal Antibody Against an Epitope on the N-terminus of Meningococcal fHbp

    Article • Scientific Reports, March 2012, Springer Science + Business Media

    Dr Dan M Granoff

  17. Monoclonal Antibodies to Meningococcal Factor H Binding Protein with Overlapping Epitopes and Discordant Functional Activity

    Article • PLoS ONE, March 2012, PLOS

    Dr Dan M Granoff

  18. Meningococcal Factor H Binding Proteins in Epidemic Strains from Africa: Implications for Vaccine Development

    Article • PLoS Neglected Tropical Diseases, September 2011, PLOS

    Dr Dan M Granoff

  19. Cooperative serum bactericidal activity between human antibodies to meningococcal factor H binding protein and Neisserial heparin binding antigen

    Article • Vaccine, February 2011, Elsevier

    Dr Dan M Granoff

  20. Review of Meningococcal Group B Vaccines

    Article • Clinical Infectious Diseases, March 2010, Oxford University Press (OUP)

    Dr Dan M Granoff

  21. Frequency of factor H-binding protein modular groups and susceptibility to cross-reactive bactericidal activity in invasive meningococcal isolates

    Article • Vaccine, February 2010, Elsevier

    Dr Dan M Granoff

  22. Relative importance of complement-mediated bactericidal and opsonic activity for protection against meningococcal disease

    Article • Vaccine, June 2009, Elsevier

    Dr Dan M Granoff

  23. A region of the N-terminal domain of meningococcal factor H-binding protein that elicits bactericidal antibody across antigenic variant groups

    Article • Molecular Immunology, May 2009, Elsevier

    Dr Dan M Granoff

  24. Bactericidal Antibody Responses Elicited by a Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Factor H–Binding Protein and Genetically Attenuated Endotoxin

    Article • The Journal of Infectious Diseases, July 2008, Oxford University Press (OUP)

    Dr Dan M Granoff

  25. Complement‐Dependent Synergistic Bactericidal Activity of Antibodies against Factor H–Binding Protein, a Sparsely Distributed Meningococcal Vaccine Antigen

    Article • The Journal of Infectious Diseases, April 2008, Oxford University Press (OUP)

    Dr Dan M Granoff

  26. Reconsideration of the Use of Meningococcal Polysaccharide Vaccine

    Article • The Pediatric Infectious Disease Journal, August 2007, Wolters Kluwer Health

    Dr Dan M Granoff

  27. Prevalence of Factor H–Binding Protein Variants and NadA among Meningococcal Group B Isolates from the United States: Implications for the Development of a Multicomponent Group B Vaccine

    Article • The Journal of Infectious Diseases, May 2007, Oxford University Press (OUP)

    Dr Dan M Granoff

  28. A novel mechanism for complement-mediated killing of encapsulated Neisseria meningitidis elicited by monoclonal antibodies to factor H-binding protein (genome-derived Neisserial antigen 1870)

    Article • Molecular Immunology, January 2007, Elsevier

    Dr Dan M Granoff

  29. Protective Antibody Responses Elicited by a Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Genome‐Derived Neisserial Antigen 1870

    Article • The Journal of Infectious Diseases, August 2005, Oxford University Press (OUP)

    Dr Dan M Granoff

  30. Antibody to Genome‐Derived Neisserial Antigen 2132, a Neisseria meningitidis Candidate Vaccine, Confers Protection against Bacteremia in the Absence of Complement‐Mediated Bactericidal Activity

    Article • The Journal of Infectious Diseases, December 2003, Oxford University Press (OUP)

    Dr Dan M Granoff

  31. Meningococcal conjugate vaccine for Africa: a model for development of new vaccines for the poorest countries

    Article • The Lancet, May 2003, Elsevier

    Dr Dan M Granoff

  32. Induction of Immunologic Refractoriness in Adults by Meningococcal C Polysaccharide Vaccination

    Article • The Journal of Infectious Diseases, September 1998, Oxford University Press (OUP)

    Dr Dan M Granoff

  33. Factors associated with superior antibody responses to a single dose of Haemophilus influenzae type b-tetanus toxoid conjugate vaccine administered to Chilean infants at 2 months of age

    Article • Vaccine, February 1997, Elsevier

    Dr Dan M Granoff

  34. Hemophilus Influenzae Type B Disease in Children Vaccinated with Type B Polysaccharide Vaccine

    Article • New England Journal of Medicine, December 1986, New England Journal of Medicine (NEJM/MMS)

    Dr Dan M Granoff

  35. IMMUNOGENICITY IN INFANTS OF HAEMOPHILUS INFLUENZAE TYPE B POLYSACCHARIDE IN A CONJUGATE VACCINE WITH NEISSERIA MENINGITIDIS OUTER-MEMBRANE PROTEIN

    Article • The Lancet, August 1986, Elsevier

    Dr Dan M Granoff

  36. A Modified ELISA for Measurement of High-Avidity IgG Antibodies to Meningococcal Serogroup C Polysaccharide that Correlate with Bactericidal Titers

    Article • Springer Science + Business Media

    Dr Dan M Granoff