All Stories

  1. Risk to heroin users of polydrug use of pregabalin or gabapentin
  2. Effect of Tamoxifen and Brain-Penetrant Protein Kinase C and c-Jun N-Terminal Kinase Inhibitors on Tolerance to Opioid-Induced Respiratory Depression in Mice
  3. The μ‐opioid receptor: an electrophysiologist's perspective from the sharp end
  4. The opioid receptor pharmacology of GSK1521498 compared to other ligands with differential effects on compulsive reward-related behaviours
  5. Identification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptor
  6. μ‐Opioid receptor desensitization: homologous or heterologous?
  7. Endocytosis of G Protein-Coupled Receptors Is Regulated by Clathrin Light Chain Phosphorylation
  8. Does alcohol increase the risk of overdose death: the need for a translational approach
  9. Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice
  10. Methadone: does it really have low efficacy at μ-opioid receptors?
  11. C-terminal splice variants of the μ-opioid receptor: existence, distribution and functional characteristics
  12. Evidence for an important role of protein phosphatases in the mechanism of morphine tolerance
  13. How important is protein kinase C in μ-opioid receptor desensitization and morphine tolerance?
  14. The British Pharmacological Society: 75 years old and thriving
  15. Opioid elevation of intracellular free calcium: Possible mechanisms and physiological relevance
  16. 75 years of opioid research: the exciting but vain quest for the Holy Grail
  17. Drug abuse: from gene through cell to behaviour
  18. Co-incident signalling between μ-opioid and M3 muscarinic receptors at the level of Ca2+ release from intracellular stores: lack of evidence for Ins(1,4,5)P3 receptor sensitization
  19. Properties of native P2X receptors in rat trigeminal mesencephalic nucleus neurones: lack of correlation with known, heterologously expressed P2X receptors
  20. Modulation of fast synaptic transmission by presynaptic ligand-gated cation channels
  21. Hyperpolarization-activated cationic currents (Ih) in neurones of the trigeminal mesencephalic nucleus of the rat
  22. Glycine and GABAAreceptor-mediated synaptic transmission in rat substantia gelatinosa: inhibition by μ-opioid and GABABagonists
  23. The orphan opioid receptor and its endogenous ligand — nociceptin/orphanin FQ
  24. Hans Walter Kosterlitz (1903–1996)
  25. Neuropeptide Y Y2 receptor and somatostatin sst2 receptor coupling to mobilization of intracellular calcium in SH-SY5Y human neuroblastoma cells
  26. The effect of nociceptin on Ca2+ channel current and intracellular Ca2+ in the SH-SY5Y human neuroblastoma cell line
  27. Ca2+ entry following store depletion in SH-SY5Y neuroblastoma cells
  28. δ- and μ-opioid receptor mobilization of intracellular calcium in SH-SY5Y human neuroblastoma cells
  29. Lack of evidence for coupling of the dopamine D2 receptor to an adenosine triphosphate-sensitive potassium (ATP-K+) channel in dopaminergic neurones of the rat substantia nigra
  30. Activation of μ- and δ-opioid receptors present on the same nerve terminals depresses transmitter release in the mouse hypogastric ganglion
  31. Characterization of two components of the N-like, high-threshold-activated calcium channel current in differentiated SH-SY5Y cells
  32. Complexity of 5-HT pharmacology compounded by electrophysiological data
  33. The ligand rimcazole antagonises (+)SKF 10,047, but not (+)3-PPP, in the mouse isolated vas deferens
  34. Characterization of the neurons of the mouse hypogastric ganglion: morphology and electrophysiology
  35. An examination of the putative σ-receptor in the mouse isolated vas deferens
  36. Effects of Angiotensin II on [3H]Noradrenaline Release and Phosphatidylinositol Hydrolysis in the Parietal Cortex and Locus Coeruleus of the Rat
  37. Locus Coeruleus Neurons
  38. Substance P excitation of rat locus coeruleus neurones
  39. Graeme Henderson writes in reply:
  40. Phenycyclidine A widely abused but little understood psychotomimetic agent
  41. The effect of extracellular sodium ion concentration on the action of opiates to inhibit potassium-evoked released of [3H]noradrenaline from the mouse vas deferens
  42. Di-isopropyl phosphofluoridate-induced antinociception: possible role of endogenous opioids
  43. In vitro pharmacology of the opioid peptides, enkephalins and endorphins
  44. Action of morphine on guinea-pig myenteric plexus and mouse vas deferens studied by intracellular recording