All Stories

  1. ChemInform Abstract: Privileged Structures: Efficient Chemical “Navigators” Toward Unexplored Biologically Relevant Chemical Spaces
  2. Unique photophysical properties of 9-styryl-1,2-dihydropyrrolo[3,4-β]indolizin-3-one and its efficient synthesis via direct C–H activation
  3. Diverse display of non-covalent interacting elements using pyrimidine-embedded polyheterocycles
  4. A small molecule binding HMGB1 and HMGB2 inhibits microglia-mediated neuroinflammation
  5. Phenotypic Screening to Identify Small-Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy
  6. Rücktitelbild: Phenotypic Screening to Identify Small-Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy (Angew. Chem. 20/2014)
  7. Phenotypic Screening to Identify Small-Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy
  8. ChemInform Abstract: Privileged Substructure-Based Diversity-Oriented Synthesis Pathway for Diverse Pyrimidine-Embedded Polyheterocycles.
  9. Rational Perturbation of the Fluorescence Quantum Yield in Emission-Tunable and Predictable Fluorophores (Seoul-Fluors) by a Facile Synthetic Method Involving CH Activation
  10. Rational Perturbation of the Fluorescence Quantum Yield in Emission-Tunable and Predictable Fluorophores (Seoul-Fluors) by a Facile Synthetic Method Involving CH Activation
  11. Impact of molecular charge on GLUT-specific cellular uptake of glucose bioprobes and in vivo application of the glucose bioprobe, GB2-Cy3
  12. Phenotypic Screening to Identify Small-Molecule Enhancers for Glucose Uptake: Target Identification and Rational Optimization of Their Efficacy
  13. Privileged Substructure-Based Diversity-Oriented Synthesis Pathway for Diverse Pyrimidine-Embedded Polyheterocycles
  14. Synthesis of Molecular Frameworks Containing Two Distinct Heterocycles Connected in a Single Molecule with Enhanced Three-Dimensional Shape Diversity
  15. Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells
  16. Discovery of a highly selective FLT3 kinase inhibitor from phenotypic cell viability profiling
  17. Fluorescent chemosensor for biological zinc ions
  18. Discovery of autophagy modulators through the construction of a high-content screening platform via monitoring of lipid droplets
  19. Total synthesis of eryvarin H and its derivatives and their biological activity as ERRγ inverse agonist
  20. From noncovalent to covalent bonds: a paradigm shift in target protein identification
  21. Optimization of Seoul-Fluor-based lipid droplet bioprobes and their application in microalgae for bio-fuel study
  22. Focus on chemical biology in Asia
  23. Colorimetric and orange light-emitting fluorescent probe for pyrophosphate in water
  24. ChemInform Abstract: Diversity-Oriented Synthesis of Privileged Heterocycles Using Divergent Strategy.
  25. Lentiviral vector-mediated shRNA against AIMP2-DX2 suppresses lung cancer cell growth through blocking glucose uptake
  26. Titelbild: Discovery and Target Identification of an Antiproliferative Agent in Live Cells Using Fluorescence Difference in Two-Dimensional Gel Electrophoresis (Angew. Chem. 22/2012)
  27. Cover Picture: Discovery and Target Identification of an Antiproliferative Agent in Live Cells Using Fluorescence Difference in Two-Dimensional Gel Electrophoresis (Angew. Chem. Int. Ed. 22/2012)
  28. Discovery and Target Identification of an Antiproliferative Agent in Live Cells Using Fluorescence Difference in Two-Dimensional Gel Electrophoresis
  29. Discovery and Target Identification of an Antiproliferative Agent in Live Cells Using Fluorescence Difference in Two-Dimensional Gel Electrophoresis
  30. ChemInform Abstract: A Design Strategy for Drug-Like Polyheterocycles with Privileged Substructures for Discovery of Specific Small-Molecule Modulators
  31. Construction of Polyheterocyclic Benzopyran Library with Diverse Core Skeletons through Diversity-Oriented Synthesis Pathway: Part II
  32. Regioselective Construction and Screening of 1,3-Disubstituted Tetrahydroindazolones in Enantiomerically Pure Pairs
  33. A Seoul-Fluor-based bioprobe for lipid droplets and its application in image-based high throughput screening
  34. Photochemical generation of a new, highly fluorescent compound from non-fluorescent resveratrol
  35. Diversity-Oriented Synthesis of Privileged Heterocycles Using Divergent Strategy
  36. Ethanol and Reactive Species Increase Basal Sequence Heterogeneity of Hepatitis C Virus and Produce Variants with Reduced Susceptibility to Antivirals
  37. ChemInform Abstract: 9-Aryl-1,2-dihydropyrrolo[3,4-b]indolizin-3-one (Seoul-Fluor) as a Smart Platform for Colorful Ratiometric Fluorescent pH Sensors
  38. Highly selective fluorescence turn-on probe for glutathione
  39. Solid-Phase Parallel Synthesis of a Tetrahydroindazolone Library Containing Three Unique Core Skeletons
  40. Bioinspired Polymerization of Dopamine to Generate Melanin-Like Nanoparticles Having an Excellent Free-Radical-Scavenging Property
  41. Pharmacophore-Based Strategy for the Development of General and Specific scFv Biosensors for Abused Antibiotics
  42. Inside Cover: Development of Fluorescent Glucose Bioprobes and Their Application on Real-Time and Quantitative Monitoring of Glucose Uptake in Living Cells (Chem. Eur. J. 1/2011)
  43. Development of Fluorescent Glucose Bioprobes and Their Application on Real-Time and Quantitative Monitoring of Glucose Uptake in Living Cells
  44. 9-Aryl-1,2-dihydropyrrolo[3,4-b]indolizin-3-one (Seoul-Fluor) as a smart platform for colorful ratiometric fluorescent pH sensors
  45. Ratiometric analysis of zidovudine (ZDV) incorporation by reverse transcriptases or polymerases via bio-orthogonal click chemistry
  46. A design strategy for drug-like polyheterocycles with privileged substructures for discovery of specific small-molecule modulators
  47. Discovery of a novel benzopyranyl compound as a potent in vitro and in vivo osteogenic agent
  48. Surface modification for small-molecule microarrays and its application to the discovery of a tyrosinase inhibitor
  49. Discovery of Novel Benzopyranyl Tetracycles that Act as Inhibitors of Osteoclastogenesis Induced by Receptor Activator of NF-κB Ligand
  50. ChemInform Abstract: Orthogonal Regioselective Synthesis of N-Alkyl-3-substituted Tetrahydroindazolones.
  51. Orthogonal Regioselective Synthesis of N-Alkyl-3-substituted Tetrahydroindazolones (Eur. J. Org. Chem. 20/2010)
  52. ChemInform Abstract: α,α-Difluorophosphonomethyl Azobenzene Derivatives as Photo-Regulated Phosphoamino Acid Analogues. Part 1. Design and Synthesis.
  53. Orthogonal Regioselective Synthesis of N-Alkyl-3-substituted Tetrahydroindazolones
  54. ChemInform Abstract: An Efficient One-Step Synthesis of Heterobiaryl Pyrazolo[3,4-b]pyridines via Indole Ring Opening.
  55. Development of a Benzopyran-Containing Androgen Receptor Antagonist to Treat Antiandrogen-Resistant Prostate Cancer
  56. Computer-aided design and synthesis of tetra-aryl-substituted alkenes and their bioevaluation as a selective modulator of estrogen-related receptor γ
  57. ChemInform Abstract: Chemistry as a Prism: A Review of Light-Emitting Materials Having Tunable Emission Wavelenghts
  58. Small Molecule Microarray: Functional-Group Specific Immobilization of Small Molecules
  59. Discovery of New Fluorescent Dyes: Targeted Synthesis or Combinatorial Approach?
  60. An Efficient One-Step Synthesis of Heterobiaryl Pyrazolo[3,4- b ]pyridines via Indole Ring Opening
  61. Chemistry as a Prism: A Review of Light-Emitting Materials Having Tunable Emission Wavelengths
  62. A Two-Photon Tracer for Glucose Uptake
  63. A Two-Photon Tracer for Glucose Uptake
  64. Efficient Discovery of Selective Small Molecule Agonists of Estrogen-Related Receptor γ using Combinatorial Approach
  65. Natural polyphenols antagonize the antimyeloma activity of proteasome inhibitor bortezomib by direct chemical interaction
  66. ChemInform Abstract: Diastereoselective Synthesis of Polycyclic Acetal-Fused Pyrano[3,2-c]pyran-5(2H)-one Derivatives.
  67. ChemInform Abstract: Efficient Parallel Synthesis of Privileged Benzopyranylpyrazoles via Regioselective Condensation of β-Keto Aldehydes with Hydrazines.
  68. Repeated Aerosol Delivery of Carboxyl-terminal Modulator Protein Suppresses Tumor in the Lungs of K-rasLA1Mice
  69. ChemInform Abstract: Regioselective Synthesis of Tetrasubstituted Pyrroles by 1,3-Dipolar Cycloaddition and Spontaneous Decarboxylation.
  70. Efficient Parallel Synthesis of Privileged Benzopyranylpyrazoles via Regioselective Condensation of β-Keto Aldehydes with Hydrazines
  71. Diastereoselective Synthesis of Polycyclic Acetal-Fused Pyrano[3,2- c ]pyran-5(2 H )-one Derivatives
  72. Fluorescent probe for detection of fluoride in water and bioimaging in A549 human lung carcinoma cells
  73. Regioselective Synthesis of Tetrasubstituted Pyrroles by 1,3-Dipolar Cycloaddition and Spontaneous Decarboxylation
  74. ChemInform Abstract: An Improved Synthesis of Pyrimidine- and Pyrazole-Based Acyclo-C-nucleosides as Carbohybrids.
  75. ChemInform Abstract: Facile and Efficient Synthesis of Carbohybrids as Stereodivergent Druglike Small Molecules.
  76. An improved synthesis of pyrimidine- and pyrazole-based acyclo-C-nucleosides as carbohybrids
  77. ChemInform Abstract: Diversity-Oriented Synthesis of Privileged Benzopyranyl Heterocycles from s-cis-Enones.
  78. Facile and Efficient Synthesis of Carbohybrids as Stereodivergent Druglike Small Molecules
  79. Diversity-Oriented Synthesis of Privileged Benzopyranyl Heterocycles from s - cis -Enones
  80. Lentiviral siRNA targeting human AIMP2-DX2 inhibits EGFR pathway from NSCLC through block of glucose uptake
  81. Polo-like kinase 2 gene expression is regulated by the orphan nuclear receptor estrogen receptor-related receptor gamma (ERRγ)
  82. Practical Solid-Phase Parallel Synthesis of Δ 5 -2-Oxopiperazines via N -Acyliminium Ion Cyclization
  83. Synthesis and in vitro photodynamic activities of water-soluble fluorinated tetrapyridylporphyrins as tumor photosensitizers
  84. Development of a Cy3-Labeled Glucose Bioprobe and Its Application in Bioimaging and Screening for Anticancer Agents
  85. Development of a Cy3-Labeled Glucose Bioprobe and Its Application in Bioimaging and Screening for Anticancer Agents
  86. Abc Amino Acids: Design, Synthesis, and Properties of New Photoelastic Amino Acids
  87. Novel application of Leuckart–Wallach reaction for synthesis of tetrahydro-1,4-benzodiazepin-5-ones library
  88. A practical procedure for producing silver nanocoated fabric and its antibacterial evaluation for biomedical applications
  89. Concise and Diversity-Oriented Synthesis of Novel Scaffolds Embedded with Privileged Benzopyran Motif.
  90. Abc Amino Acids:  Design, Synthesis, and Properties of New Photoelastic Amino Acids
  91. Preparation of pilot library with tetrahydro-β-carboline alkaloid core skeleton using tandem intramolecular Pictet–Spengler cyclization
  92. A Robust Small-Molecule Microarray Platform for Screening Cell Lysates
  93. Concise and diversity-oriented synthesis of novel scaffolds embedded with privileged benzopyran motif
  94. Solid-Phase Parallel Synthesis of Natural Product-Like Diaza-Bridged Heterocycles through Pictet−Spengler Intramolecular Cyclization
  95. Simple Mimetics of a Nuclear Localization Signal (NLS)
  96. Expanding the Functional Group Compatibility of Small-Molecule Microarrays: Discovery of Novel Calmodulin Ligands
  97. Titelbild: Expanding the Functional Group Compatibility of Small-Molecule Microarrays: Discovery of Novel Calmodulin Ligands (Angew. Chem. 21/2003)
  98. Skeletal Diversity via a Branched Pathway:  Efficient Synthesis of 29 400 Discrete, Polycyclic Compounds and Their Arraying into Stock Solutions
  99. Study of the characteristics of three high-energy intermediates generated in peroxyoxalate chemiluminescence (PO-CL) reactions
  100. A photoregulated ligand for the nuclear import receptor karyopherin α
  101. A simple, solid-phase binding assay for the nuclear import receptor karyopherin α. Part 2: competitive binding
  102. A simple, solid-phase binding assay for the nuclear import receptor karyopherin α. Part 1: direct binding
  103. α,α-Difluorophosphonomethyl azobenzene derivatives as photo-regulated phosphoamino acid analogs. 1. Design and synthesis