All Stories

  1. Testing structural identifiability by a simple scaling method

    Article • February 2020, Cold Spring Harbor Laboratory Press

    Professor Rob J de Boer

  2. Modeling the immunological pre-adaptation of HIV-1

    Article • January 2020, Cold Spring Harbor Laboratory Press

    Professor Rob J de Boer

  3. Characterization of the ferret TRB locus guided by V, D, J, and C gene expression analysis

    Article • Immunogenetics, December 2019, Springer Science + Business Media

    Dr ir Wilfred van IJcken, Professor Rob J de Boer

  4. Toxin production spontaneously becomes regulated by local cell density in evolving bacterial populations

    Article • PLoS Computational Biology, August 2019, PLOS

    Professor Rob J de Boer

  5. The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes

    Article • July 2019, Cold Spring Harbor Laboratory Press

    Professor Rob J de Boer

  6. Local Attachment Explains Small World–like Properties of Fibroblastic Reticular Cell Networks in Lymph Nodes

    Article • The Journal of Immunology, April 2019, The American Association of Immunologists

    Professor Rob J de Boer

  7. Stochastic Inheritance of Division and Death Times Determines the Size and Phenotype of CD8+ T Cell Families

    Article • Frontiers in Immunology, March 2019, Frontiers

    Professor Rob J de Boer

  8. Early and Highly Suppressive Antiretroviral Therapy Are Main Factors Associated With Low Viral Reservoir in European Perinatally HIV-Infected Children

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, October 2018, Wolters Kluwer Health

    Professor Rob J de Boer

  9. Short Lifespans of Memory T-cells in Bone Marrow, Blood, and Lymph Nodes Suggest That T-cell Memory Is Maintained by Continuous Self-Renewal of Recirculating Cells

    Article • Frontiers in Immunology, September 2018, Frontiers

    Professor Rob J de Boer

  10. Robust self-nonself discrimination requires negative T cell selection on non-random peptides

    Article • August 2018, Cold Spring Harbor Laboratory Press

    Professor Rob J de Boer

  11. Current best estimates for the average lifespans of mouse and human leukocytes: reviewing two decades of deuterium-labeling experiments

    Article • Immunological Reviews, August 2018, Wiley

    Professor Rob J de Boer

  12. Local Attachment Explains Small-World-Like Properties of Fibroblastic Reticular Cell Networks in Lymph Nodes

    Article • July 2018, Cold Spring Harbor Laboratory Press

    Professor Rob J de Boer

  13. Estimation of age-specific susceptibility to influenza in the Netherlands and its relation to loss of CD8+ T-cell memory

    Article • February 2018, Cold Spring Harbor Laboratory Press

    Professor Rob J de Boer

  14. How Germinal Centers Evolve Broadly Neutralizing Antibodies: the Breadth of the Follicular Helper T Cell Response

    Article • Journal of Virology, September 2017, ASM Journals

    Professor Rob J de Boer

  15. Dynamics of Recent Thymic Emigrants in Young Adult Mice

    Article • Frontiers in Immunology, August 2017, Frontiers

    Professor Rob J de Boer

  16. An evolutionary perspective on the systems of adaptive immunity

    Article • Biological Reviews, July 2017, Wiley

    Viktor Müller, Professor Rob J de Boer

  17. Circulatory and maturation kinetics of human monocyte subsets in vivo

    Article • Blood, July 2017, American Society of Hematology

    Professor Rob J de Boer

  18. Specificity of inhibitory KIRs enables NK cells to detect changes in an altered peptide environment

    Article • Immunogenetics, July 2017, Springer Science + Business Media

    Professor Rob J de Boer

  19. Cytokines and Chemokines Involved in Acute Retinal Necrosis

    Article • Investigative Opthalmology & Visual Science, May 2017, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Rob J de Boer

  20. A Sigmoid Functional Response Emerges When Cytotoxic T Lymphocytes Start Killing Fresh Target Cells

    Article • Biophysical Journal, March 2017, Elsevier

    Professor Rob J de Boer

  21. Tissue Dimensionality Influences the Functional Response of Cytotoxic T Lymphocyte-Mediated Killing of Targets

    Article • Frontiers in Immunology, January 2017, Frontiers

    Professor Rob J de Boer

  22. How lymphocytes add up

    Article • Nature Immunology, December 2016, Nature

    Professor Rob J de Boer

  23. The Reticular Cell Network: A Robust Backbone for Immune Responses

    Article • PLoS Biology, October 2016, PLOS

    Professor Rob J de Boer

  24. Long-term adaptation of the influenza A virus by escaping cytotoxic T-cell recognition

    Article • Scientific Reports, September 2016, Springer Science + Business Media

    Professor Rob J de Boer

  25. RTCR: a pipeline for complete and accurate recovery of T cell repertoires from high throughput sequencing data

    Article • Bioinformatics, June 2016, Oxford University Press (OUP)

    Professor Rob J de Boer

  26. Notwithstanding Circumstantial Alibis, Cytotoxic T Cells Can Be Major Killers of HIV-1-Infected Cells

    Article • Journal of Virology, May 2016, ASM Journals

    Professor Rob J de Boer

  27. Quantifying the effect of Vpu on the promotion of HIV-1 replication in the humanized mouse model

    Article • Retrovirology, April 2016, Springer Science + Business Media

    Professor Rob J de Boer

  28. Reconciling Longitudinal Naive T-Cell and TREC Dynamics during HIV-1 Infection

    Article • PLoS ONE, March 2016, PLOS

    Professor Rob J de Boer

  29. Slowing Down of Recovery as Generic Risk Marker for Acute Severity Transitions in Chronic Diseases

    Article • Critical Care Medicine, March 2016, Wolters Kluwer Health

    Professor Rob J de Boer

  30. HIV-1 CCR5 gene therapy will fail unless it is combined with a suicide gene

    Article • Scientific Reports, December 2015, Nature

    Professor Rob J de Boer

  31. The Branching Point in Erythro-Myeloid Differentiation

    Article • Cell, December 2015, Elsevier

    Professor Rob J de Boer

  32. Subtle CXCR3-Dependent Chemotaxis of CTLs within Infected Tissue Allows Efficient Target Localization

    Article • The Journal of Immunology, November 2015, The American Association of Immunologists

    Professor Rob J de Boer

  33. What do mathematical models tell us about killing rates during HIV-1 infection?

    Article • Immunology Letters, November 2015, Elsevier

    Professor Rob J de Boer

  34. Crawling and Gliding: A Computational Model for Shape-Driven Cell Migration

    Article • PLoS Computational Biology, October 2015, PLOS

    Professor Rob J de Boer

  35. Reconciling Estimates of Cell Proliferation from Stable Isotope Labeling Experiments

    Article • PLoS Computational Biology, October 2015, PLOS

    Professor Rob J de Boer

  36. Quantification of naive and memory T-cell turnover during HIV-1 infection

    Article • AIDS, October 2015, Wolters Kluwer Health

    Professor Rob J de Boer

  37. The evolution of natural killer cell receptors

    Article • Immunogenetics, September 2015, Springer Science + Business Media

    Professor Rob J de Boer

  38. Common myeloid progenitors are made up of distinct subpopulations that either yield erythrocytes or myeloid cells

    Article • Experimental Hematology, September 2015, Elsevier

    Professor Rob J de Boer

  39. Can Selective MHC Downregulation Explain the Specificity and Genetic Diversity of NK Cell Receptors?

    Article • Frontiers in Immunology, June 2015, Frontiers

    Professor Rob J de Boer

  40. Optimal T cell cross-reactivity and the role of regulatory T cells

    Article • Journal of Theoretical Biology, June 2015, Elsevier

    Professor Rob J de Boer

  41. A Coevolutionary Arms Race between Hosts and Viruses Drives Polymorphism and Polygenicity of NK Cell Receptors

    Article • Molecular Biology and Evolution, April 2015, Oxford University Press (OUP)

    Professor Rob J de Boer

  42. HIV Molecular Immunology 2014

    Article • February 2015, Office of Scientific and Technical Information (OSTI)

    Professor Rob J de Boer

  43. Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover

    Article • Aging Cell, January 2015, Wiley

    Professor Rob J de Boer

  44. Corrigendum: Quantifying the Protection of Activating and Inhibiting NK Cell Receptors during Infection with a CMV-Like Virus

    Article • Frontiers in Immunology, January 2015, Frontiers

    Professor Rob J de Boer

  45. Immune system modeling and analysis

    Article • January 2015

    Professor Rob J de Boer

  46. Immuno-epidemiological Modeling of HIV-1 Predicts High Heritability of the Set-Point Virus Load, while Selection for CTL Escape Dominates Virulence Evolution

    Article • PLoS Computational Biology, December 2014, PLOS

    Professor Rob J de Boer

  47. Random Migration and Signal Integration Promote Rapid and Robust T Cell Recruitment

    Article • PLoS Computational Biology, August 2014, PLOS

    Professor Rob J de Boer

  48. Combining cellular barcoding and mathematical modeling to infer the structure of the hematopoietic pathway

    Article • Experimental Hematology, August 2014, Elsevier

    Professor Rob J de Boer

  49. A General Functional Response of Cytotoxic T Lymphocyte-Mediated Killing of Target Cells

    Article • Biophysical Journal, April 2014, Elsevier

    Professor Rob J de Boer

  50. Determining Lineage Pathways from Cellular Barcoding Experiments

    Article • Cell Reports, February 2014, Elsevier

    Professor Rob J de Boer, Shalin Naik

  51. Quantifying the Protection of Activating and Inhibiting NK Cell Receptors during Infection with a CMV-Like Virus

    Article • Frontiers in Immunology, January 2014, Frontiers

    Professor Rob J de Boer

  52. Reliable reconstruction of HIV-1 whole genome haplotypes reveals clonal interference and genetic hitchhiking among immune escape variants

    Article • Retrovirology, January 2014, Springer Science + Business Media

    Professor Rob J de Boer

  53. Improving the estimation of the death rate of infected cells from time course data during the acute phase of virus infections: application to acute HIV-1 infection in a humanized mouse model

    Article • Theoretical Biology and Medical Modelling, January 2014, Springer Science + Business Media

    Professor Rob J de Boer

  54. Induction of appropriate Th‐cell phenotypes: cellular decision‐making in heterogeneous environments

    Article • Parasite Immunology, October 2013, Wiley

    Professor Rob J de Boer

  55. Virus Encoded MHC-Like Decoys Diversify the Inhibitory KIR Repertoire

    Article • PLoS Computational Biology, October 2013, PLOS

    Professor Rob J de Boer

  56. Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans

    Article • Blood, September 2013, American Society of Hematology

    Professor Rob J de Boer

  57. Diverse and heritable lineage imprinting of early hematopoietic progenitors

    Article • Experimental Hematology, August 2013, Elsevier

    Professor Rob J de Boer, Shalin Naik

  58. Quantifying T lymphocyte turnover

    Article • Journal of Theoretical Biology, June 2013, Elsevier

    Professor Rob J de Boer

  59. Diverse and heritable lineage imprinting of early haematopoietic progenitors

    Article • Nature, April 2013, Nature

    Professor Rob J de Boer, Shalin Naik

  60. Early divergence of Th1 and Th2 transcriptomes involves a small core response and sets of transiently expressed genes

    Article • European Journal of Immunology, March 2013, Wiley

    Professor Rob J de Boer, Dr ir Wilfred van IJcken

  61. Immune Activation and Collateral Damage in AIDS Pathogenesis

    Article • Frontiers in Immunology, January 2013, Frontiers

    Professor Rob J de Boer

  62. Analytical results on the Beauchemin model of lymphocyte migration

    Article • BMC Bioinformatics, January 2013, Springer Science + Business Media

    Professor Rob J de Boer

  63. A new model to simulate and analyze proliferating cell populations in BrdU labeling experiments

    Article • BMC Systems Biology, January 2013, Springer Science + Business Media

    Professor Rob J de Boer

  64. Complementarity of Binding Motifs is a General Property of HLA-A and HLA-B Molecules and Does Not Seem to Effect HLA Haplotype Composition

    Article • Frontiers in Immunology, January 2013, Frontiers

    Professor Rob J de Boer

  65. Chemotactic Migration of T Cells towards Dendritic Cells Promotes the Detection of Rare Antigens

    Article • PLoS Computational Biology, November 2012, PLOS

    Professor Rob J de Boer

  66. A Generalized Mathematical Model To Estimate T- and B-Cell Receptor Diversities Using AmpliCot

    Article • Biophysical Journal, September 2012, Elsevier

    Professor Rob J de Boer

  67. Which of Our Modeling Predictions Are Robust?

    Article • PLoS Computational Biology, July 2012, PLOS

    Professor Rob J de Boer

  68. Cell division curtails helper phenotype plasticity and expedites helper T-cell differentiation

    Article • Immunology and Cell Biology, May 2012, Nature

    Professor Rob J de Boer

  69. Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity

    Article • Journal of The Royal Society Interface, April 2012, Royal Society Publishing

    Professor Rob J de Boer

  70. Impaired immune evasion in HIV through intracellular delays and multiple infection of cells

    Article • Proceedings of the Royal Society B Biological Sciences, April 2012, Royal Society Publishing

    Professor Rob J de Boer

  71. Degenerate T-cell Recognition of Peptides on MHC Molecules Creates Large Holes in the T-cell Repertoire

    Article • PLoS Computational Biology, March 2012, PLOS

    Professor Rob J de Boer

  72. Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans

    Article • Immunity, February 2012, Elsevier

    Professor Rob J de Boer

  73. Identifying viral parameters from in vitro cell cultures

    Article • Frontiers in Microbiology, January 2012, Frontiers

    Professor Rob J de Boer

  74. Response: The in vivo half-life of human neutrophils

    Article • Blood, June 2011, American Society of Hematology

    Professor Rob J de Boer

  75. Implications of CTL-Mediated Killing of HIV-Infected Cells during the Non-Productive Stage of Infection

    Article • PLoS ONE, February 2011, PLOS

    Professor Rob J de Boer

  76. Killing of Targets by CD8+ T Cells in the Mouse Spleen Follows the Law of Mass Action

    Article • PLoS ONE, January 2011, PLOS

    Professor Rob J de Boer, Dr Vitaly V Ganusov

  77. Current Estimates for HIV-1 Production Imply Rapid Viral Clearance in Lymphoid Tissues

    Article • PLoS Computational Biology, September 2010, PLOS

    Professor Rob J de Boer

  78. Identification of helper T cell master regulator candidates using the polar score method

    Article • Journal of Immunological Methods, September 2010, Elsevier

    Professor Rob J de Boer

  79. Quantifying how MHC polymorphism prevents pathogens from adapting to the antigen presentation pathway

    Article • Epidemics, September 2010, Elsevier

    Professor Rob J de Boer

  80. In Mice, Tuberculosis Progression Is Associated with Intensive Inflammatory Response and the Accumulation of Gr-1dim Cells in the Lungs

    Article • PLoS ONE, May 2010, PLOS

    Dr Vitaly V Ganusov, Professor Rob J de Boer

  81. Intracellular transactivation of HIV can account for the decelerating decay of virus load during drug therapy

    Article • Molecular Systems Biology, February 2010, EMBO

    Professor Rob J de Boer

  82. Explicit Kinetic Heterogeneity: Mathematical Models for Interpretation of Deuterium Labeling of Heterogeneous Cell Populations

    Article • PLoS Computational Biology, February 2010, PLOS

    Professor Rob J de Boer, Dr Vitaly V Ganusov

  83. Analysing immune cell migration

    Article • Nature Reviews Immunology, October 2009, Springer Science + Business Media

    Professor Rob J de Boer

  84. Towards estimating the true duration of dendritic cell interactions with T cells

    Article • Journal of Immunological Methods, August 2009, Elsevier

    Professor Rob J de Boer

  85. Correction: The Specificity and Polymorphism of the MHC Class I Prevents the Global Adaptation of HIV-1 to the Monomorphic Proteasome and TAP

    Article • PLoS ONE, January 2009, PLOS

    Professor Rob J de Boer

  86. The distribution of CTL epitopes in HIV-1 appears to be random, and similar to that of other proteomes

    Article • BMC Evolutionary Biology, January 2009, Springer Science + Business Media

    Professor Rob J de Boer

  87. The Specificity and Polymorphism of the MHC Class I Prevents the Global Adaptation of HIV-1 to the Monomorphic Proteasome and TAP

    Article • PLoS ONE, October 2008, PLOS

    Professor Rob J de Boer

  88. The Contribution of the Thymus to the Recovery of Peripheral Naive T-Cell Numbers During Antiretroviral Treatment for HIV Infection

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, September 2008, Wolters Kluwer Health

    Professor Rob J de Boer

  89. Dynamics of Immune Escape during HIV/SIV Infection

    Article • PLoS Computational Biology, July 2008, PLOS

    Professor Rob J de Boer

  90. Tissue distribution of lymphocytes and plasma cells and the role of the gut: response to Pabst et al.

    Article • Trends in Immunology, May 2008, Elsevier

    Professor Rob J de Boer

  91. Sparse production but preferential incorporation of recently produced naïve T cells in the human peripheral pool

    Article • Proceedings of the National Academy of Sciences, April 2008, Proceedings of the National Academy of Sciences

    Professor Rob J de Boer

  92. Amino Acid Similarity Accounts for T Cell Cross-Reactivity and for “Holes” in the T Cell Repertoire

    Article • PLoS ONE, March 2008, PLOS

    Professor Rob J de Boer

  93. Do most lymphocytes in humans really reside in the gut?

    Article • Trends in Immunology, December 2007, Elsevier

    Professor Rob J de Boer, Dr Vitaly V Ganusov

  94. HLA Alleles Associated with Slow Progression to AIDS Truly Prefer to Present HIV-1 p24

    Article • PLoS ONE, September 2007, PLOS

    Professor Rob J de Boer

  95. Time Scales of CD4+ T Cell Depletion in HIV Infection

    Article • PLoS Medicine, May 2007, PLOS

    Professor Rob J de Boer

  96. Spatial modelling of brief and long interactions between T cells and dendritic cells

    Article • Immunology and Cell Biology, April 2007, Nature

    Professor Rob J de Boer

  97. Lymph node topology dictates T cell migration behavior

    Article • The Journal of Cell Biology, April 2007, Rockefeller University Press

    Professor Rob J de Boer

  98. Lymph node topology dictates T cell migration behavior

    Article • The Journal of Experimental Medicine, March 2007, Rockefeller University Press

    Professor Rob J de Boer

  99. MHC diversity in Individuals and Populations

    Article • January 2007, Springer Science + Business Media

    Professor Rob J de Boer

  100. Erratum to “Quantifying cell turnover using CFSE data” [J. Immunol. Methods (298) (2005) 183]

    Article • Journal of Immunological Methods, December 2006, Elsevier

    Professor Rob J de Boer

  101. Estimating Lymphocyte Division and Death Rates from CFSE Data

    Article • The Bulletin of Mathematical Biophysics, May 2006, Springer Science + Business Media

    Professor Rob J de Boer, Dr Vitaly V Ganusov

  102. The Integration Hypothesis: An Evolutionary Pathway to Benign SIV Infection

    Article • PLoS Pathogens, March 2006, PLOS

    Viktor Müller, Professor Rob J de Boer

  103. Estimating the role of thymic output in HIV infection

    Article • Current Opinion in HIV and AIDS, January 2006, Wolters Kluwer Health

    Professor Rob J de Boer

  104. Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection

    Article • PLoS Computational Biology, January 2006, PLOS

    Professor Rob J de Boer, Dr Vitaly V Ganusov

  105. Estimating division and death rates from CFSE data

    Article • Journal of Computational and Applied Mathematics, December 2005, Elsevier

    Professor Rob J de Boer

  106. A Mathematical Model of Protein Degradation by the Proteasome

    Article • Biophysical Journal, April 2005, Elsevier

    Professor Rob J de Boer

  107. Quantifying cell turnover using CFSE data

    Article • Journal of Immunological Methods, March 2005, Elsevier

    Professor Rob J de Boer, Dr Vitaly V Ganusov

  108. Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection

    Article • PLoS Computational Biology, January 2005, PLOS

    Professor Rob J de Boer

  109. Discriminating self from nonself with short peptides from large proteomes

    Article • Immunogenetics, July 2004, Springer Science + Business Media

    Professor Rob J de Boer

  110. MHC polymorphism under host-pathogen coevolution

    Article • Immunogenetics, January 2004, Springer Science + Business Media

    Professor Rob J de Boer

  111. Heterozygote advantage fails to explain the high degree of polymorphism of the MHC

    Article • Immunogenetics, January 2004, Springer Science + Business Media

    Professor Rob J de Boer

  112. Thymic selection does not limit the individual MHC diversity

    Article • European Journal of Immunology, December 2003, Wiley

    Professor Rob J de Boer

  113. Decline in excision circles requires homeostatic renewal or homeostatic death of naive T cells

    Article • Journal of Theoretical Biology, October 2003, Elsevier

    Prof. Dr. Bas E. Dutilh, Professor Rob J de Boer

  114. Bioinformatic analysis of functional differences between the immunoproteasome and the constitutive proteasome

    Article • Immunogenetics, August 2003, Springer Science + Business Media

    Professor Rob J de Boer

  115. The race between initial T–helper expansion and virus growth upon HIV infection influences polyclonality of the response and viral set–point

    Article • Proceedings of the Royal Society B Biological Sciences, July 2003, Royal Society Publishing

    Professor Rob J de Boer

  116. Depletion of naive CD4 T cells by CXCR4-using HIV-1 variants occurs mainly through increased T-cell death and activation

    Article • AIDS, July 2003, Wolters Kluwer Health

    Professor Rob J de Boer

  117. A spatial model of germinal center reactions: cellular adhesion based sorting of B cells results in efficient affinity maturation

    Article • Journal of Theoretical Biology, May 2003, Elsevier

    Professor Rob J de Boer

  118. IL-2 therapy and thymic production of naive CD4 T cells in HIV-infected patients with severe CD4 lymphopenia

    Article • AIDS, April 2003, Wolters Kluwer Health

    Professor Rob J de Boer

  119. Thymic output: a bad TREC record

    Article • Nature Immunology, February 2003, Nature

    Professor Rob J de Boer

  120. Reconstitution of naive T cells during antiretroviral treatment of HIV-infected adults is dependent on age

    Article • AIDS, November 2002, Wolters Kluwer Health

    Professor Rob J de Boer

  121. Resource Competition Determines Selection of B Cell Repertoires

    Article • Journal of Theoretical Biology, October 2001, Elsevier

    Professor Rob J de Boer

  122. Selection by AZT and Rapid Replacement in the Absence of Drugs of HIV Type 1 Resistant to Multiple Nucleoside Analogs

    Article • AIDS Research and Human Retroviruses, June 2001, Mary Ann Liebert Inc

    Professor Rob J de Boer

  123. The Dominant Source of CD4+ and CD8+ T-Cell Activation in HIV Infection Is Antigenic Stimulation

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, November 2000, Wolters Kluwer Health

    Professor Rob J de Boer

  124. The Dominant Source of CD4+ and CD8+ T-Cell Activation in HIV Infection Is Antigenic Stimulation

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, November 2000, Wolters Kluwer Health

    Professor Rob J de Boer

  125. Predicting the duration of antiviral treatment needed to suppress plasma HIV-1 RNA

    Article • Journal of Clinical Investigation, March 2000, American Society for Clinical Investigation

    Professor Rob J de Boer

  126. Normal Telomere Lengths in Naive and Memory CD4+ T Cells in HIV Type 1 Infection: A Mathematical Interpretation

    Article • AIDS Research and Human Retroviruses, August 1999, Mary Ann Liebert Inc

    Professor Rob J de Boer

  127. T Cell Dynamics in HIV-1 Infection

    Article • January 1999, Elsevier

    Professor Rob J de Boer

  128. Early recovery of CD4+ T lymphocytes in children on highly active antiretroviral therapy

    Article • AIDS, November 1998, Wolters Kluwer Health

    Professor Rob J de Boer

  129. Crossreactivity of the T-cell receptor

    Article • Immunology Today, September 1998, Elsevier

    Professor Rob J de Boer

  130. Target cell availability and the successful suppression of HIV by hydroxyurea and didanosine

    Article • AIDS, September 1998, Wolters Kluwer Health

    Professor Rob J de Boer

  131. Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation

    Article • Nature Reports Stem Cells, February 1998, Nature

    Professor Rob J de Boer

  132. Overshoot of HIV-1 viraemia after early discontinuation of antiretroviral treatment

    Article • AIDS, September 1997, Wolters Kluwer Health

    Professor Rob J de Boer

  133. T-cell vaccination: Insights and questions raised by a mathematical model

    Article • Immunology Letters, May 1997, Elsevier

    Professor Rob J de Boer

  134. Reduction of memory cytotoxic T cell numbers by heterologous viral infections: A mathematical model

    Article • Immunology Letters, May 1997, Elsevier

    Professor Rob J de Boer

  135. The context of an immune response: Interactions between innate and adaptive immunity

    Article • Immunology Letters, May 1997, Elsevier

    Professor Rob J de Boer

  136. A Formal Derivation of the “Beddington” Functional Response

    Article • Journal of Theoretical Biology, April 1997, Elsevier

    Professor Rob J de Boer

  137. Self Assertion Modeled as a Network Repertoire of Multi-Determinant Antibodies

    Article • Journal of Theoretical Biology, November 1996, Elsevier

    Professor Rob J de Boer

  138. A new bell-shaped function for idiotypic interactions based on cross-linking

    Article • The Bulletin of Mathematical Biophysics, March 1996, Springer Science + Business Media

    Professor Rob J de Boer

  139. Extending the quasi-steady state approximation by changing variables

    Article • The Bulletin of Mathematical Biophysics, January 1996, Springer Science + Business Media

    Professor Rob J de Boer

  140. Implications of Spatial Heterogeneity for the Paradox of Enrichment

    Article • Ecology, October 1995, Wiley

    Professor Rob J de Boer

  141. Towards a general function describing t cell proliferation

    Article • Journal of Theoretical Biology, August 1995, Elsevier

    Professor Rob J de Boer

  142. T Cell Repertoires and Competitive Exclusion

    Article • Journal of Theoretical Biology, August 1994, Elsevier

    Professor Rob J de Boer

  143. Immune network behavior—II. From oscillations to chaos and stationary states

    Article • The Bulletin of Mathematical Biophysics, July 1993, Springer Science + Business Media

    Professor Rob J de Boer

  144. Immune network behavior—I. From stationary states to limit cycle oscilations

    Article • The Bulletin of Mathematical Biophysics, July 1993, Springer Science + Business Media

    Professor Rob J de Boer

  145. Dynamics of HIV infection of CD4+ T cells

    Article • Mathematical Biosciences, March 1993, Elsevier

    Professor Rob J de Boer

  146. Pattern formation in one- and two-dimensional shape-space models of the immune system

    Article • Journal of Theoretical Biology, April 1992, Elsevier

    Professor Rob J de Boer

  147. Growth and Recruitment in the Immune Network

    Article • January 1992, Springer Science + Business Media

    Professor Rob J de Boer

  148. Size and connectivity as emergent properties of a developing immune network

    Article • Journal of Theoretical Biology, April 1991, Elsevier

    Professor Rob J de Boer

  149. Allelic variations of human TCR V gene products

    Article • Immunology Today, January 1991, Elsevier

    Professor Rob J de Boer

  150. Localized memories in idiotypic networks

    Article • Journal of Theoretical Biology, October 1990, Elsevier

    Professor Rob J de Boer

  151. Poor repertoire selection in symmetric idiotypic network models

    Article • Immunology Letters, August 1989, Elsevier

    Professor Rob J de Boer

  152. Proceedings of a one-day symposium held in Utrecht, The Netherlands, May 1989

    Article • Immunology Letters, August 1989, Elsevier

    Professor Rob J de Boer

  153. Idiotypic networks incorporating T-B cell co-operation. The conditions for percolation

    Article • Journal of Theoretical Biology, July 1989, Elsevier

    Professor Rob J de Boer

  154. Unreasonable implications of reasonable idiotypic network assumptions

    Article • The Bulletin of Mathematical Biophysics, May 1989, Springer Science + Business Media

    Professor Rob J de Boer

  155. Stability of symmetric idiotypic networks—a critique of Hoffmann's analysis

    Article • The Bulletin of Mathematical Biophysics, March 1989, Springer Science + Business Media

    Professor Rob J de Boer

  156. Memory but no suppression in low-dimensional symmetric idiotypic networks

    Article • The Bulletin of Mathematical Biophysics, March 1989, Springer Science + Business Media

    Professor Rob J de Boer

  157. Information processing in immune systems: Clonal selection versus idiotypic network models

    Article • January 1989, Elsevier

    Professor Rob J de Boer

  158. Immunological discrimination between self and non-self by precursor depletion and memory accumulation

    Article • Journal of Theoretical Biology, February 1987, Elsevier

    Professor Rob J de Boer

  159. Self-Nonself Discrimination due to Immunological Nonlinearities: the Analysis of a Series of Models by Numerical Methods

    Article • Mathematical Medicine and Biology A Journal of the IMA, January 1987, Oxford University Press (OUP)

    Professor Rob J de Boer

  160. Interactions between macrophages and T-lymphocytes: Tumor sneaking through intrinsic to helper T cell dynamics

    Article • Journal of Theoretical Biology, June 1986, Elsevier

    Professor Rob J de Boer

  161. Implications of Macrophage T-Lymphocyte Interactions for Tumor Rejectability

    Article • January 1986, Springer Science + Business Media

    Professor Rob J de Boer

  162. Mathematical analysis of the cellular immune reaction against tumour cells

    Article • Immunology Today, November 1985, Elsevier

    Professor Rob J de Boer

  163. The effect of group size on time budgets and social behaviour in wild long-tailed macaques (Macaca fascicularis)

    Article • Behavioral Ecology and Sociobiology, September 1983, Springer Science + Business Media

    Professor Rob J de Boer

  164. Diversity and virulence thresholds in AIDS

    Article • Cambridge University Press

    Professor Rob J de Boer

  165. Major Histocompatibility Complex: Polymorphism from Coevolution

    Article • Cambridge University Press

    Professor Rob J de Boer