All Stories

  1. Discovery of Cell-Permeable Inhibitors That Target the BRCT Domain of BRCA1 Protein by Using a Small-Molecule Microarray

    Article • Angewandte Chemie International Edition, June 2014, Wiley

    Dr Mahesh Uttamchandani

  2. In Situ Proteome Profiling of C75, a Covalent Bioactive Compound with Potential Anticancer Activities

    Article • Organic Letters, February 2014, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  3. A tuned affinity-based staurosporine probe for in situ profiling of protein kinases

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  4. Preparation of Small-Molecule Microarrays bytrans-Cyclooctene Tetrazine Ligation and Their Application in the High-Throughput Screening of Protein-Protein Interaction Inhibitors of Bromodomains

    Article • Angewandte Chemie, November 2013, Wiley

    Dr Mahesh Uttamchandani

  5. Preparation of Small-Molecule Microarrays bytrans-Cyclooctene Tetrazine Ligation and Their Application in the High-Throughput Screening of Protein-Protein Interaction Inhibitors of Bromodomains

    Article • Angewandte Chemie International Edition, November 2013, Wiley

    Dr Mahesh Uttamchandani

  6. Faculty Opinions recommendation of DNA catalysts with tyrosine kinase activity.

    Article • October 2013, F1000Research

    Dr Mahesh Uttamchandani

  7. Faculty Opinions recommendation of Investigation of SSEA-4 binding protein in breast cancer cells.

    Article • October 2013, F1000Research

    Dr Mahesh Uttamchandani

  8. Profiling human Src homology 2 (SH2) domain proteins and ligand discovery using a peptide-hybrid small molecule microarray

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  9. Fluorescence-activated cell sorting and directed evolution of α-N-acetylgalactosaminidases using a quenched activity-based probe (qABP)

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  10. Direct visual detection of Salmonella genomic DNA using gold nanoparticles

    Article • Molecular BioSystems, January 2013, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  11. Visual DNA Detection and SNP Genotyping Using Asymmetric PCR and Split DNA Enzymes

    Article • January 2013, Springer Science + Business Media

    Dr Mahesh Uttamchandani

  12. Phosphopeptide Microarrays for Comparative Proteomic Profiling of Cellular Lysates

    Article • January 2013, Springer Science + Business Media

    Dr Mahesh Uttamchandani

  13. Current advances in peptide and small molecule microarray technologies

    Article • Current Opinion in Chemical Biology, April 2012, Elsevier

    Dr Mahesh Uttamchandani

  14. Comparative proteomic profiling of mammalian cell lysates using phosphopeptide microarrays

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  15. Microarray-guided discovery of two-photon (2P) small molecule probes for live-cell imaging of cysteinyl cathepsin activities

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  16. Developing Influenza Antigen Microarrays for Seroprofiling

    Article • January 2012, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  17. Applying Small Molecule Microarrays and Resulting Affinity Probe Cocktails for Proteome Profiling of Mammalian Cell Lysates

    Article • Chemistry - An Asian Journal, September 2011, Wiley

    Dr Mahesh Uttamchandani

  18. Multicolor, One- and Two-Photon Imaging of Enzymatic Activities in Live Cells with Fluorescently Quenched Activity-Based Probes (qABPs)

    Article • Journal of the American Chemical Society, August 2011, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  19. ChemInform Abstract: Small Molecule Microarrays: The First Decade and Beyond

    Article • ChemInform, July 2011, Wiley

    Dr Mahesh Uttamchandani

  20. Faculty Opinions recommendation of Fluorescence imaging of influenza H1N1 mRNA in living infected cells using single-chromophore FIT-PNA.

    Article • April 2011, F1000Research

    Dr Mahesh Uttamchandani

  21. A Peptide Aldehyde Microarray for High-Throughput Profiling of Cellular Events

    Article • Journal of the American Chemical Society, February 2011, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  22. Visual SNP genotyping using asymmetric PCR and split DNA enzymes

    Article • The Analyst, January 2011, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  23. Small molecule microarrays: the first decade and beyond

    Article • Chemical Communications, January 2011, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  24. Compound Heterozygosity in Brugada Syndrome: A Case Study

    Article • Journal of Arrhythmia, January 2011, Elsevier

    Dr Mahesh Uttamchandani

  25. Brugada Syndrome and SCN5A-Encoded Cardiac Sodium Channel Mutations in Singapore

    Article • Journal of Arrhythmia, January 2011, Elsevier

    Dr Mahesh Uttamchandani

  26. Faculty Opinions recommendation of Real-time SNP analysis in secondary-structure-folded nucleic acids.

    Article • December 2010, F1000Research

    Dr Mahesh Uttamchandani

  27. Faculty Opinions recommendation of Imaging tuberculosis with endogenous beta-lactamase reporter enzyme fluorescence in live mice.

    Article • June 2010, F1000Research

    Dr Mahesh Uttamchandani

  28. Faculty Opinions recommendation of A protein microarray-based analysis of S-nitrosylation.

    Article • April 2010, F1000Research

    Dr Mahesh Uttamchandani

  29. ChemInform Abstract: Next Generation Chemical Proteomic Tools for Rapid Enzyme Profiling

    Article • ChemInform, January 2010, Wiley

    Dr Mahesh Uttamchandani

  30. Visual detection of DNA from salmonella and mycobacterium using split DNAzymes

    Article • Molecular BioSystems, January 2010, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  31. Small Molecule Microarrays

    Article • January 2010

    Dr Mahesh Uttamchandani

  32. Nanodroplet Microarrays for High-Throughput Enzyme Screening

    Article • January 2010, Springer Science + Business Media

    Dr Mahesh Uttamchandani

  33. The Expanding World of Small Molecule Microarrays

    Article • January 2010, Springer Science + Business Media

    Dr Mahesh Uttamchandani

  34. High-Throughput Screening of Metalloproteases Using Small Molecule Microarrays

    Article • January 2010, Springer Science + Business Media

    Dr Mahesh Uttamchandani

  35. A Method for Small Molecule Microarray-Based Screening for the Rapid Discovery of Affinity-Based Probes

    Article • January 2010, Springer Science + Business Media

    Dr Mahesh Uttamchandani

  36. Next Generation Chemical Proteomic Tools for Rapid Enzyme Profiling

    Article • Accounts of Chemical Research, August 2009, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  37. Faculty Opinions recommendation of Libraries against libraries for combinatorial selection of replicating antigen-antibody pairs.

    Article • March 2009, F1000Research

    Dr Mahesh Uttamchandani

  38. Applications of microarrays in pathogen detection and biodefence

    Article • Trends in Biotechnology, January 2009, Elsevier

    Dr Mahesh Uttamchandani

  39. Rapid Affinity-Based Fingerprinting of 14-3-3 Isoforms Using a Combinatorial Peptide Microarray

    Article • Angewandte Chemie International Edition, September 2008, Wiley

    Dr Mahesh Uttamchandani

  40. Rapid Affinity-Based Fingerprinting of 14-3-3 Isoforms Using a Combinatorial Peptide Microarray

    Article • Angewandte Chemie International Edition, September 2008, Wiley

    Dr Mahesh Uttamchandani

  41. Peptide Microarrays: Next Generation Biochips for Detection, Diagnostics and High-Throughput Screening

    Article • Current Pharmaceutical Design, August 2008, Bentham Science Publishers

    Dr Mahesh Uttamchandani

  42. ChemInform Abstract: Activity-Based Protein Profiling: New Developments and Directions in Functional Proteomics

    Article • ChemInform, June 2008, Wiley

    Dr Mahesh Uttamchandani

  43. Activity-Based Protein Profiling: New Developments and Directions in Functional Proteomics

    Article • ChemBioChem, March 2008, Wiley

    Dr Mahesh Uttamchandani

  44. Peptide Microarray for High-Throughput Determination of Phosphatase Specificity and Biology

    Article • Angewandte Chemie, February 2008, Wiley

    Dr Mahesh Uttamchandani

  45. Peptide Microarray for High-Throughput Determination of Phosphatase Specificity and Biology

    Article • Angewandte Chemie International Edition, February 2008, Wiley

    Dr Mahesh Uttamchandani

  46. Quantitative Inhibitor Fingerprinting of Metalloproteases Using Small Molecule Microarrays

    Article • Journal of the American Chemical Society, October 2007, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  47. Inhibitor fingerprinting of metalloproteases using microplate and microarray platforms: an enabling technology in Catalomics

    Article • Nature Protocols, August 2007, Springer Science + Business Media

    Dr Mahesh Uttamchandani

  48. Inhibitor Fingerprinting of Matrix Metalloproteases Using a Combinatorial Peptide Hydroxamate Library

    Article • Journal of the American Chemical Society, June 2007, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  49. Small Molecule Microarrays: Applications Using Specially Tagged Chemical Libraries

    Article • ChemInform, January 2007, Wiley

    Dr Mahesh Uttamchandani

  50. Activity-based fingerprinting and inhibitor discovery of cysteine proteases in a microarray

    Article • Chemical Communications, January 2007, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  51. Small Molecule Microarrays: Applications Using Specially Tagged Chemical Libraries

    Article • QSAR & Combinatorial Science, November 2006, Wiley

    Dr Mahesh Uttamchandani

  52. Rapid Assembly of Matrix Metalloprotease Inhibitors Using Click Chemistry

    Article • Organic Letters, August 2006, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  53. Microarray: A Versatile Platform for High-Throughput Functional Proteomics

    Article • Combinatorial Chemistry & High Throughput Screening, March 2006, Bentham Science Publishers

    Dr Mahesh Uttamchandani

  54. Rapid Assembly and in Situ Screening of Bidentate Inhibitors of Protein Tyrosine Phosphatases

    Article • Organic Letters, February 2006, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  55. “Click” synthesis of small molecule probes for activity-based fingerprinting of matrix metalloproteases

    Article • Chemical Communications, January 2006, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  56. Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays

    Article • Chemical Communications, January 2006, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  57. Protein and small molecule microarrays: powerful tools for high-throughput proteomics

    Article • Molecular BioSystems, January 2006, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  58. Nanodroplet profiling of enzymatic activities in a microarray

    Article • Bioorganic & Medicinal Chemistry Letters, April 2005, Elsevier

    Dr Mahesh Uttamchandani

  59. Small molecule microarrays: recent advances and applications

    Article • Current Opinion in Chemical Biology, February 2005, Elsevier

    Dr Mahesh Uttamchandani

  60. Microarrays of Tagged Combinatorial Triazine Libraries in the Discovery of Small-Molecule Ligands of Human IgG

    Article • Journal of Combinatorial Chemistry, November 2004, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  61. Cell-Permeable Small Molecule Probes for Site-Specific Labeling of Proteins.

    Article • ChemInform, March 2004, Wiley

    Dr Mahesh Uttamchandani

  62. Application of Microarrays in High-Throughput Enzymatic Profiling

    Article • Molecular Biotechnology, January 2004, Springer Science + Business Media

    Dr Mahesh Uttamchandani

  63. Combinatorial peptide microarrays for the rapid determination of kinase specificity

    Article • Bioorganic & Medicinal Chemistry Letters, September 2003, Elsevier

    Dr Mahesh Uttamchandani

  64. Enzymatic Profiling System in a Small-Molecule Microarray

    Article • Organic Letters, April 2003, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  65. Developing a Strategy for Activity-Based Detection of Enzymes in a Protein Microarray

    Article • ChemBioChem, March 2003, Wiley

    Dr Mahesh Uttamchandani

  66. Solid-Phase Synthesis of Peptide Vinyl Sulfones as Potential Inhibitors and Activity-Based Probes of Cysteine Proteases

    Article • Organic Letters, March 2003, American Chemical Society (ACS)

    Dr Mahesh Uttamchandani

  67. Facile synthesis of 7-amino-4-carbamoylmethylcoumarin (ACC)-containing solid supports and Their corresponding fluorogenic protease substrates

    Article • Bioorganic & Medicinal Chemistry Letters, March 2003, Elsevier

    Dr Mahesh Uttamchandani

  68. Array-Based Technologies and their Applications in Proteomics

    Article • Current Topics in Medicinal Chemistry, February 2003, Bentham Science Publishers

    Dr Mahesh Uttamchandani

  69. Cell-permeable small molecule probes for site-specific labeling of proteinsElectronic supplementary information (ESI) available: experimental details and characterization of compounds. See http://www.rsc.org/suppdata/cc/b3/b309196a/

    Article • Chemical Communications, January 2003, Royal Society of Chemistry

    Dr Mahesh Uttamchandani

  70. Antibody-Based fluorescence detection of kinase activity on a peptide array

    Article • Bioorganic & Medicinal Chemistry Letters, August 2002, Elsevier

    Dr Mahesh Uttamchandani

  71. Developing site-Specific immobilization strategies of peptides in a microarray

    Article • Bioorganic & Medicinal Chemistry Letters, August 2002, Elsevier

    Dr Mahesh Uttamchandani

  72. Substrate spectrum of tyrocidine thioesterase probed with randomized peptide N-acetylcysteamine thioesters

    Article • Bioorganic & Medicinal Chemistry Letters, March 2002, Elsevier

    Dr Mahesh Uttamchandani

  73. Site-Specific Peptide Immobilization Strategies for the Rapid Detection of Kinase Activity on Microarrays

    Article • Springer Science + Business Media

    Dr Mahesh Uttamchandani