All Stories

  1. Environmental Disruption of Circadian Rhythm Predisposes Mice to Osteoarthritis-Like Changes in Knee Joint

    Article • Journal of Cellular Physiology, May 2015, Wiley

    Dr Hee-Jeong Im

  2. Licochalcone-A induces intrinsic and extrinsic apoptosis via ERK1/2 and p38 phosphorylation-mediated TRAIL expression in head and neck squamous carcinoma FaDu cells

    Article • Food and Chemical Toxicology, March 2015, Elsevier

    Dr Hee-Jeong Im

  3. Berberine induces FasL-related apoptosis through p38 activation in KB human oral cancer cells

    Article • Oncology Reports, January 2015, Spandidos Publications

    Dr Hee-Jeong Im

  4. MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc

    Article • Gene, January 2015, Elsevier

    Dr Hee-Jeong Im

  5. Environmental Lead Exposure and Attention-Deficit/Hyperactivity Disorder Symptom Domains in a Community Sample of South Korean School-Age Children

    Article • Environmental Health Perspectives, October 2014, Environmental Health Perspectives

    Dr Hee-Jeong Im

  6. Assessment of Knee Joint Pain in Experimental Rodent Models of Osteoarthritis

    Article • September 2014, Springer Science + Business Media

    Dr Hee-Jeong Im

  7. High-Resolution Molecular Validation of Self-Renewal and Spontaneous Differentiation in Clinical-Grade Adipose-Tissue Derived Human Mesenchymal Stem Cells

    Article • Journal of Cellular Biochemistry, August 2014, Wiley

    Dr Hee-Jeong Im, Professor Sanjeev Kakar

  8. Pain assessment in animal models of osteoarthritis

    Article • Gene, March 2014, Elsevier

    Dr Hee-Jeong Im

  9. Deletion of the Transforming Growth Factor β Receptor Type II Gene in Articular Chondrocytes Leads to a Progressive Osteoarthritis-like Phenotype in Mice

    Article • Arthritis & Rheumatism, November 2013, Wiley

    Dr Hee-Jeong Im

  10. Altered Spinal MicroRNA-146a and the MicroRNA-183 Cluster Contribute to Osteoarthritic Pain in Knee Joints

    Article • Journal of Bone and Mineral Research, November 2013, Wiley

    Dr Hee-Jeong Im

  11. Anti-Angiogenic Effect of Triptolide in Rheumatoid Arthritis by Targeting Angiogenic Cascade

    Article • PLoS ONE, October 2013, PLOS

    Dr Hee-Jeong Im

  12. The anti-catabolic role of bovine lactoferricin in cartilage

    Article • BioMolecular Concepts, October 2013, De Gruyter

    Dr Hee-Jeong Im

  13. A current review of molecular mechanisms regarding osteoarthritis and pain

    Article • Gene, September 2013, Elsevier

    Dr Hee-Jeong Im

  14. ATF4 promotes bone angiogenesis by increasing vegf expression and release in the bone environment

    Article • Journal of Bone and Mineral Research, August 2013, Wiley

    Dr Hee-Jeong Im

  15. Lactoferricin enhances BMP7-stimulated anabolic pathways in intervertebral disc cells

    Article • Gene, July 2013, Elsevier

    Dr Hee-Jeong Im

  16. HGF Mediates the Anti-inflammatory Effects of PRP on Injured Tendons

    Article • PLoS ONE, June 2013, PLOS

    Dr Hee-Jeong Im

  17. Lactoferricin mediates anti-inflammatory and anti-catabolic effects via inhibition of IL-1 and LPS activity in the intervertebral disc

    Article • Journal of Cellular Physiology, May 2013, Wiley

    Dr Hee-Jeong Im

  18. MicroRNA Functions in Osteogenesis and Dysfunctions in Osteoporosis

    Article • Current Osteoporosis Reports, April 2013, Springer Science + Business Media

    Dr Hee-Jeong Im, Professor Sanjeev Kakar

  19. Bovine lactoferricin induces TIMP-3 via the ERK1/2-Sp1 axis in human articular chondrocytes

    Article • Gene, March 2013, Elsevier

    Dr Hee-Jeong Im

  20. Anti-inflammatory effect of Sosihotang via inhibition of nuclear factor-κB and mitogen-activated protein kinases signaling pathways in lipopolysaccharide-stimulated RAW 264.7 macrophage cells

    Article • Food and Chemical Toxicology, March 2013, Elsevier

    Dr Hee-Jeong Im

  21. PKCδ as a Regulator for TGFβ1-Induced α-SMA Production in a Murine Nonalcoholic Steatohepatitis Model

    Article • PLoS ONE, February 2013, PLOS

    Dr Hee-Jeong Im

  22. Volumetric bone regenerative efficacy of biphasic calcium phosphate-collagen composite block loaded with rhBMP-2 in vertical bone augmentation model of a rabbit calvarium

    Article • Journal of Biomedical Materials Research Part A, February 2013, Wiley

    Dr Hee-Jeong Im

  23. Factors Associated with Serum Levels of Carcinoembryonic Antigen in Healthy Non-smokers

    Article • Korean Journal of Family Medicine, January 2013, The Korean Academy of Family Medicine (KAMJE)

    Dr Hee-Jeong Im

  24. Chondrocyte BMP2 signaling plays an essential role in bone fracture healing

    Article • Gene, January 2013, Elsevier

    Dr Hee-Jeong Im

  25. ADAR1 ablation decreases bone mass by impairing osteoblast function in mice

    Article • Gene, January 2013, Elsevier

    Dr Hee-Jeong Im

  26. ATF4 Promotes β-Catenin Expression and Osteoblastic Differentiation of Bone Marrow Mesenchymal Stem Cells

    Article • International Journal of Biological Sciences, January 2013, Ivyspring International Publisher

    Dr Hee-Jeong Im

  27. MMP13 is a critical target gene during the progression of osteoarthritis

    Article • Arthritis Research & Therapy, January 2013, Springer Science + Business Media

    Dr Hee-Jeong Im

  28. Bovine lactoferricin is anti-inflammatory and anti-catabolic in human articular cartilage and synovium

    Article • Journal of Cellular Physiology, October 2012, Wiley

    Dr Hee-Jeong Im

  29. Toll-like receptor adaptor signaling molecule MyD88 on intervertebral disk homeostasis: In vitro, ex vivo studies

    Article • Gene, September 2012, Elsevier

    Dr Hee-Jeong Im

  30. Reply

    Article • Arthritis & Rheumatism, August 2012, Wiley

    Dr Hee-Jeong Im

  31. Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue

    Article • Arthritis & Rheumatism, July 2012, Wiley

    Dr Hee-Jeong Im

  32. Fibroblast growth factor‐2 promotes catabolism via FGFR1‐Ras‐Raf‐MEK1/2‐ERK1/2 axis that coordinates with the PKCδ pathway in human articular chondrocytes

    Article • Journal of Cellular Biochemistry, July 2012, Wiley

    Dr Hee-Jeong Im

  33. Rabbit calvarium augmentation by rhBMP-2 and synthetic scaffold

    Article • Journal of Biomedical Materials Research Part A, June 2012, Wiley

    Dr Hee-Jeong Im, Dr. Kwang il Lee

  34. Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development

    Article • Journal of Cellular Physiology, June 2012, Wiley

    Dr Hee-Jeong Im

  35. Biological effects of the plant-derived polyphenol resveratrol in human articular cartilage and chondrosarcoma cells

    Article • Journal of Cellular Physiology, June 2012, Wiley

    Dr Hee-Jeong Im

  36. Anti-inflammatory effect of Lycium Fruit water extract in lipopolysaccharide-stimulated RAW 264.7 macrophage cells

    Article • International Immunopharmacology, June 2012, Elsevier

    Dr Hee-Jeong Im

  37. The pathophysiologic role of the protein kinase Cδ pathway in the intervertebral discs of rabbits and mice: In vitro, ex vivo, and in vivo studies

    Article • Arthritis & Rheumatism, May 2012, Wiley

    Dr Hee-Jeong Im

  38. Species-specific biological effects of FGF-2 in articular cartilage: Implication for distinct roles within the FGF receptor family

    Article • Journal of Cellular Biochemistry, May 2012, Wiley

    Dr Hee-Jeong Im

  39. Morphology controlled fabrication and ferroelectric properties of vertically aligned one-dimensional lead titanate nanoarrays

    Article • Nanotechnology, March 2012, Institute of Physics Publishing

    Dr Hee-Jeong Im

  40. Fermentation by Lactobacillus enhances anti-inflammatory effect of Oyaksungisan on LPS-stimulated RAW 264.7 mouse macrophage cells

    Article • BMC Complementary and Alternative Medicine, March 2012, Springer Science + Business Media

    Dr Hee-Jeong Im

  41. Biochemical Mediators Involved in Cartilage Degradation and the Induction of Pain in Osteoarthritis

    Article • February 2012, IntechOpen

    Dr Hee-Jeong Im

  42. Lactoferricin mediates anabolic and anti‐catabolic effects in the intervertebral disc

    Article • Journal of Cellular Physiology, January 2012, Wiley

    Dr Hee-Jeong Im

  43. Anti-Inflammatory Effect of Citrus Unshiu Peel in LPS-Stimulated RAW 264.7 Macrophage Cells

    Article • The American Journal of Chinese Medicine, January 2012, World Scientific Pub Co Pte Lt

    Dr Hee-Jeong Im

  44. Lumbar Facet Joint Compressive Injury Induces Lasting Changes in Local Structure, Nociceptive Scores, and Inflammatory Mediators in a Novel Rat Model

    Article • Pain Research and Treatment, January 2012, Hindawi Publishing Corporation

    Dr Hee-Jeong Im

  45. A Novel Herbal Medicine KIOM-MA Exerts an Anti-Inflammatory Effect in LPS-Stimulated RAW 264.7 Macrophage Cells

    Article • Evidence-based Complementary and Alternative Medicine, January 2012, Hindawi Publishing Corporation

    Dr Hee-Jeong Im

  46. 장소 경험 분석을 통한 도시 내 장소성 특성 연구

    Article • Journal of the Korean Institute of Landscape Architecture, December 2011, Korean Institute of Landscape Architecture

    Dr Hee-Jeong Im

  47. Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis

    Article • Annals of the New York Academy of Sciences, December 2011, Wiley

    Dr Hee-Jeong Im

  48. Enucleated Nucleus Pulposus-Induced Intervertebral Disc Degeneration as an Animal Model for Chronic Low Back Pain

    Article • The Spine Journal, October 2011, Elsevier

    Dr Hee-Jeong Im

  49. Characterization of a new animal model for evaluation and treatment of back pain due to lumbar facet joint osteoarthritis

    Article • Arthritis & Rheumatism, September 2011, Wiley

    Dr Hee-Jeong Im

  50. Preclinical Pharmacokinetics and Biodistribution of Human Papillomavirus DNA Vaccine Delivered in Human Endogenous Retrovirus Envelope-Coated Baculovirus Vector

    Article • Pharmaceutical Research, September 2011, Springer Science + Business Media

    Dr Hee-Jeong Im

  51. Maltosylated polyethylenimine-based triple nanocomplexes of human papillomavirus 16L1 protein and DNA as a vaccine co-delivery system

    Article • Biomaterials, July 2011, Elsevier

    Dr Hee-Jeong Im

  52. MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis

    Article • Gene, July 2011, Elsevier

    Dr Hee-Jeong Im

  53. Differential properties of human ACL and MCL stem cells may be responsible for their differential healing capacity

    Article • BMC Medicine, June 2011, Springer Science + Business Media

    Dr Hee-Jeong Im

  54. 효소 처리와 유산균 배양에 의한 흑마늘의 항산화 활성 향상

    Article • Journal of the Korean Society of Food Science and Nutrition, May 2011, The Korean Society of Food Science and Nutrition

    Dr Hee-Jeong Im

  55. Osteoarthritic tissues modulate functional properties of sensory neurons associated with symptomatic OA pain

    Article • Molecular Biology Reports, February 2011, Springer Science + Business Media

    Dr Hee-Jeong Im

  56. The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain

    Article • Arthritis Research & Therapy, January 2011, Springer Science + Business Media

    Dr Hee-Jeong Im

  57. Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

    Article • Arthritis Research & Therapy, January 2011, Springer Science + Business Media

    Dr Hee-Jeong Im

  58. Insulin-like growth factor 1 synergizes with bone morphogenetic protein 7-mediated anabolism in bovine intervertebral disc cells

    Article • Arthritis & Rheumatism, November 2010, Wiley

    Dr Hee-Jeong Im

  59. Emerging roles of SUMO modification in arthritis

    Article • Gene, October 2010, Elsevier

    Dr Hee-Jeong Im

  60. Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model

    Article • Arthritis & Rheumatism, June 2010, Wiley

    Dr Hee-Jeong Im

  61. Induction of CD44 cleavage in articular chondrocytes

    Article • Arthritis & Rheumatism, February 2010, Wiley

    Dr Hee-Jeong Im

  62. Basic fibroblast growth factor induces matrix metalloproteinase-13 via ERK MAP kinase-altered phosphorylation and sumoylation of Elk-1 in human adult articular chondrocytes

    Article • Open Access Rheumatology Research and Reviews, October 2009, Taylor & Francis

    Dr Hee-Jeong Im

  63. 56. Primary Bovine Intervertebral Disc Cells Transduced with Adenovirus Overexpressing Twelve BMPs and SOX9 Maintain Their Chondrocyte-Like Phenotype

    Article • The Spine Journal, October 2009, Elsevier

    Dr Hee-Jeong Im

  64. 206. BMP7 and IGF-1 Combination Treatment Induces TGF-Beta SMAD2/3 Signaling Pathway in Bovine Intervertebral Disc Cell

    Article • The Spine Journal, October 2009, Elsevier

    Dr Hee-Jeong Im

  65. 24. IGF-1 Enhances BMP7-Mediated Anabolism Via Suppression of Noggin Expression in Intervertebral Disc Cells

    Article • The Spine Journal, October 2009, Elsevier

    Dr Hee-Jeong Im

  66. Enhanced cytotoxicity of 5-FU by bFGF through up-regulation of uridine phosphorylase 1

    Article • Molecules and Cells, August 2009, Springer Science + Business Media

    Dr Hee-Jeong Im

  67. Primary Bovine Intervertebral Disc Cells Transduced with Adenovirus Overexpressing 12 BMPs and Sox9 Maintain Appropriate Phenotype

    Article • American Journal of Physical Medicine & Rehabilitation, June 2009, Wolters Kluwer Health

    Dr Hee-Jeong Im

  68. Modulation of osteocalcin expression by purmorphamine derivatives

    Article • Genes & Genomics, June 2009, Springer Science + Business Media

    Dr Hee-Jeong Im

  69. Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis

    Article • Arthritis & Rheumatism, February 2009, Wiley

    Dr Hee-Jeong Im

  70. Prostaglandin E2and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis

    Article • Arthritis & Rheumatism, February 2009, Wiley

    Dr Hee-Jeong Im

  71. Analysis of genetic and non-genetic factors that affect the QTc interval in a Mongolian population: the GENDISCAN study

    Article • Experimental & Molecular Medicine, January 2009, Springer Science + Business Media

    Dr Hee-Jeong Im

  72. The Action of Resveratrol, a Phytoestrogen Found in Grapes, on the Intervertebral Disc

    Article • Spine, November 2008, Wolters Kluwer Health

    Dr Hee-Jeong Im

  73. 97. The Pathophysiological Role of the PKCdelta Pathway in the Intervertebral Disc

    Article • The Spine Journal, September 2008, Elsevier

    Dr Hee-Jeong Im

  74. 199. Basic Fibroblast Growth Factor Antagonizes the Action of BMP7 in the Intervertebral Disc

    Article • The Spine Journal, September 2008, Elsevier

    Dr Hee-Jeong Im

  75. Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis

    Article • Gene, August 2008, Elsevier

    Dr Hee-Jeong Im

  76. Changes in bone markers after once-weekly low-dose alendronate in postmenopausal women with moderate bone loss

    Article • Maturitas, June 2008, Elsevier

    Dr Hee-Jeong Im

  77. Retinol-binding protein 4 responses during an oral glucose tolerance testing in women with gestational diabetes mellitus

    Article • Clinica Chimica Acta, May 2008, Elsevier

    Dr Hee-Jeong Im

  78. Action of fibroblast growth factor-2 on the intervertebral disc

    Article • Arthritis Research & Therapy, January 2008, Springer Science + Business Media

    Dr Hee-Jeong Im

  79. Basic fibroblast growth factor accelerates matrix degradation via a neuro-endocrine pathway in human adult articular chondrocytes

    Article • Journal of Cellular Physiology, January 2008, Wiley

    Dr Hee-Jeong Im

  80. 116. The Action of Resveratrol, A Phytoestrogen Found in Grapes and Red Wine, on the Intervertebral Disc

    Article • The Spine Journal, September 2007, Elsevier

    Dr Hee-Jeong Im

  81. Mechanoregulation of gene expression in fibroblasts

    Article • Gene, April 2007, Elsevier

    Dr Hee-Jeong Im

  82. EP4 receptor regulates collagen type-I, MMP-1, and MMP-3 gene expression in human tendon fibroblasts in response to IL-1β treatment

    Article • Gene, January 2007, Elsevier

    Dr Hee-Jeong Im

  83. Leukotriene B4 at low dosage negates the catabolic effect of prostaglandin E2 in human patellar tendon fibroblasts

    Article • Gene, May 2006, Elsevier

    Dr Hee-Jeong Im

  84. Glutathione-enhancing agents protect against steatohepatitis in a dietary model

    Article • Journal of Biochemical and Molecular Toxicology, January 2006, Wiley

    Dr Hee-Jeong Im

  85. Repetitive mechanical stretching modulates IL-1β induced COX-2, MMP-1 expression, and PGE2 production in human patellar tendon fibroblasts

    Article • Gene, December 2005, Elsevier

    Dr Hee-Jeong Im

  86. Hyaluronan oligosaccharide-induced activation of transcription factors in bovine articular chondrocytes

    Article • Arthritis & Rheumatism, January 2005, Wiley

    Dr Hee-Jeong Im

  87. Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis

    Article • Arthritis & Rheumatism, January 2005, Wiley

    Dr Hee-Jeong Im

  88. Basic fibroblast growth factor inhibits the anabolic activity of insulin-like growth factor 1 and osteogenic protein 1 in adult human articular chondrocytes

    Article • Arthritis & Rheumatism, January 2005, Wiley

    Dr Hee-Jeong Im

  89. Immediate early gene X-1 interacts with proteins that modulate apoptosis

    Article • Biochemical and Biophysical Research Communications, October 2004, Elsevier

    Dr Hee-Jeong Im

  90. Pretreatment of indole-3-carbinol augments TRAIL-induced apoptosis in a prostate cancer cell line, LNCaP

    Article • FEBS Letters, May 2003, Wiley

    Dr Hee-Jeong Im

  91. A Novel Vitamin D-Regulated Immediate-Early Gene, IEX-1, Alters Cellular Growth and Apoptosis

    Article • January 2003, Springer Science + Business Media

    Dr Hee-Jeong Im

  92. Characterization of a novel hexameric repeat DNA sequence in the promoter of the immediate early gene, IEX-1, that mediates 1α,25-dihydroxyvitamin D3-associated IEX-1 gene repression

    Article • Oncogene, May 2002, Springer Science + Business Media

    Dr Hee-Jeong Im

  93. Opioid receptor gene: cytokine response element and the effect of cytokines

    Article • Brain Research, May 1999, Elsevier

    Dr Hee-Jeong Im