All Stories

  1. Selective regulation of axonal growth from developing hippocampal neurons by tumor necrosis factor superfamily member APRIL

    Article • Molecular and Cellular Neuroscience, March 2014, Elsevier

    Professor Alun M Davies

  2. TNFα reverse signaling promotes sympathetic axon growth and target innervation

    Article • Nature Neuroscience, June 2013, Springer Science + Business Media

    Professor Alun M Davies

  3. Regulation of neurite growth by tumour necrosis superfamily member RANKL

    Article • Open Biology, January 2013, Royal Society Publishing

    Professor Alun M Davies

  4. Regulation of neural process growth, elaboration and structural plasticity by NF-κB

    Article • Trends in Neurosciences, June 2011, Elsevier

    Professor Alun M Davies

  5. Faculty Opinions recommendation of Nna1 mediates Purkinje cell dendritic development via lysyl oxidase propeptide and NF-κB signaling.

    Article • April 2011, F1000Research

    Professor Alun M Davies

  6. Selective regulation of nerve growth factor expression in developing cutaneous tissue by early sensory innervation

    Article • Neural Development, January 2011, Springer Science + Business Media

    Professor Alun M Davies

  7. Faculty Opinions recommendation of Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not.

    Article • October 2010, F1000Research

    Professor Alun M Davies

  8. Extracellular signals regulating sympathetic neuron survival and target innervation during development

    Article • Autonomic Neuroscience, November 2009, Elsevier

    Professor Alun M Davies

  9. Macrophage stimulating protein is a neurotrophic factor for a sub-population of adult nociceptive sensory neurons

    Article • Molecular and Cellular Neuroscience, June 2009, Elsevier

    Professor Alun M Davies

  10. A function for the calponin family member NP25 in neurite outgrowth

    Article • Developmental Biology, September 2008, Elsevier

    Professor Alun M Davies, Dr Epaminondas Doxakis

  11. HAND transcription factors are required for neonatal sympathetic neuron survival

    Article • EMBO Reports, August 2008, EMBO

    Professor Alun M Davies, Dr Epaminondas Doxakis

  12. Neurotrophins giveth and they taketh away

    Article • Nature Neuroscience, June 2008, Springer Science + Business Media

    Professor Alun M Davies

  13. Bacterial lipopolysaccharide regulates nociceptin expression in sensory neurons

    Article • Journal of Neuroscience Research, April 2008, Wiley

    Professor Alun M Davies

  14. Regulation of sympathetic neuron differentiation by endogenous nerve growth factor and neurotrophin-3

    Article • Neuroscience Letters, February 2008, Elsevier

    Professor Alun M Davies

  15. Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor

    Article • Nature Neuroscience, January 2008, Springer Science + Business Media

    Professor Alun M Davies

  16. NGF-promoted axon growth and target innervation requires GITRL-GITR signaling

    Article • Nature Neuroscience, January 2008, Springer Science + Business Media

    Professor Alun M Davies

  17. A fast and accurate procedure for deriving the Sholl profile in quantitative studies of neuronal morphology

    Article • Journal of Neuroscience Methods, June 2007, Elsevier

    Professor Alun M Davies

  18. Novel class of pain drugs based on antagonism of NGF

    Article • Trends in Pharmacological Sciences, February 2006, Elsevier

    Professor Alun M Davies

  19. Retinoic acid negatively regulates GDNF and neurturin receptor expression and responsiveness in embryonic chicken sympathetic neurons

    Article • Molecular and Cellular Neuroscience, August 2005, Elsevier

    Professor Alun M Davies, Dr Epaminondas Doxakis

  20. Neurotrophins: A Ticket to Ride for BDNF

    Article • Current Biology, April 2005, Elsevier

    Professor Alun M Davies

  21. HGF promotes survival and growth of maturing sympathetic neurons by PI-3 kinase- and MAP kinase-dependent mechanisms

    Article • Molecular and Cellular Neuroscience, December 2004, Elsevier

    Professor Alun M Davies

  22. Homeodomain-Interacting Protein Kinase-2 Regulates Apoptosis in Developing Sensory and Sympathetic Neurons

    Article • Current Biology, October 2004, Elsevier

    Professor Alun M Davies, Dr Epaminondas Doxakis

  23. Macrophage-stimulating protein is a neurotrophic factor for embryonic chicken hypoglossal motoneurons

    Article • European Journal of Neuroscience, January 2002, Wiley

    Professor Alun M Davies, Dr Epaminondas Doxakis

  24. Faculty Opinions recommendation of Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins.

    Article • October 2001, F1000Research

    Professor Alun M Davies

  25. Faculty Opinions recommendation of Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.

    Article • October 2001, F1000Research

    Professor Alun M Davies

  26. Coupling Met to Specific Pathways Results in Distinct Developmental Outcomes

    Article • Molecular Cell, June 2001, Elsevier

    Professor Alun M Davies

  27. Trophic Support

    Article • April 2001, Wiley

    Professor Alun M Davies

  28. Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein

    Article • The EMBO Journal, August 2000, Wiley

    Professor Alun M Davies

  29. Induction of neuronal death by α-synuclein

    Article • European Journal of Neuroscience, August 2000, Wiley

    Professor Alun M Davies

  30. Neurotrophins: More to NGF than just survival

    Article • Current Biology, May 2000, Elsevier

    Professor Alun M Davies

  31. Neurotrophins: Neurotrophic modulation of neurite growth

    Article • Current Biology, March 2000, Elsevier

    Professor Alun M Davies

  32. Differences in Bcl-2- and Bax-independent function in regulating apoptosis in sensory neuron populations

    Article • European Journal of Neuroscience, March 2000, Wiley

    Professor Alun M Davies

  33. TrkB expression and early sensory neuron survival are independent of endogenous BDNF

    Article • Journal of Neuroscience Research, February 2000, Wiley

    Professor Alun M Davies

  34. TrkB expression and early sensory neuron survival are independent of endogenous BDNF

    Article • Journal of Neuroscience Research, February 2000, Wiley

    Professor Alun M Davies

  35. In vivo survival requirement of a subset of nodose ganglion neurons for nerve growth factor

    Article • European Journal of Neuroscience, February 2000, Wiley

    Professor Alun M Davies

  36. Mutations in the gene encoding human persyn are not associated with amyotrophic lateral sclerosis or familial Parkinson's disease

    Article • Neuroscience Letters, October 1999, Elsevier

    Professor Alun M Davies

  37. Identifying Components of Max Factor

    Article • Neuron, September 1999, Elsevier

    Professor Alun M Davies

  38. p75-Mediated NF-κB Activation Enhances the Survival Response of Developing Sensory Neurons to Nerve Growth Factor

    Article • Molecular and Cellular Neuroscience, July 1999, Elsevier

    Professor Alun M Davies

  39. Differences and Developmental Changes in the Responsiveness of PNS Neurons to GDNF and Neurturin

    Article • Molecular and Cellular Neuroscience, June 1999, Elsevier

    Professor Alun M Davies, Dr Epaminondas Doxakis

  40. GFRα-4 and the tyrosine kinase Ret form a functional receptor complex for persephin

    Article • Current Biology, September 1998, Elsevier

    Professor Alun M Davies

  41. Point Mutation in trkB Causes Loss of NT4-Dependent Neurons without Major Effects on Diverse BDNF Responses

    Article • Neuron, August 1998, Elsevier

    Professor Alun M Davies, Gary Lewin

  42. TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons

    Article • Current Biology, July 1998, Elsevier

    Professor Alun M Davies

  43. GFRα1 Is an Essential Receptor Component for GDNF in the Developing Nervous System and Kidney

    Article • Neuron, July 1998, Elsevier

    Professor Alun M Davies

  44. GFRα-4, a New GDNF Family Receptor

    Article • Molecular and Cellular Neuroscience, June 1998, Elsevier

    Professor Alun M Davies, Dr Epaminondas Doxakis

  45. Multiple Roles for Hepatocyte Growth Factor in Sympathetic Neuron Development

    Article • Neuron, May 1998, Elsevier

    Professor Alun M Davies

  46. Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages

    Article • European Journal of Neuroscience, February 1998, Wiley

    Professor Alun M Davies

  47. Neuronal survival: Early dependence on Schwann cells

    Article • Current Biology, January 1998, Elsevier

    Professor Alun M Davies

  48. Chapter 5 Developmental changes in the neurotrophic factor survival requirements of peripheral nervous system neurons

    Article • January 1998, Elsevier

    Professor Alun M Davies

  49. Studies of neurotrophin biology in the developing trigeminal system

    Article • Journal of Anatomy, November 1997, Wiley

    Professor Alun M Davies

  50. Bcl-2 influences axonal growth rate in embryonic sensory neurons

    Article • Current Biology, October 1997, Elsevier

    Professor Alun M Davies

  51. Neurotrophin switching: where does it stand?

    Article • Current Opinion in Neurobiology, February 1997, Elsevier

    Professor Alun M Davies

  52. Neurotrophins: The yin and yang of nerve growth factor

    Article • Current Biology, January 1997, Elsevier

    Professor Alun M Davies

  53. NGF Binding to p75 Enhances the Sensitivity of Sensory and Sympathetic Neurons to NGF at Different Stages of Development

    Article • Molecular and Cellular Neuroscience, January 1997, Elsevier

    Professor Alun M Davies

  54. Timing and Regulation oftrkBand BDNF mRNA Expression in Placode-derived Sensory Neurons and their Targets

    Article • European Journal of Neuroscience, November 1996, Wiley

    Professor Alun M Davies

  55. Paracrine and autocrine actions of neurotrophic factors

    Article • Neurochemical Research, July 1996, Springer Science + Business Media

    Professor Alun M Davies

  56. Characterization of a multicomponent receptor for GDNF

    Article • Nature, July 1996, Springer Science + Business Media

    Professor Alun M Davies

  57. Intracellular Compartmentalization of Two Differentially Spliceds-rex/NSPmRNAs in Neurons

    Article • Molecular and Cellular Neuroscience, April 1996, Elsevier

    Professor Alun M Davies

  58. Paracrine Interactions of BDNF Involving NGF-Dependent Embryonic Sensory Neurons

    Article • Molecular and Cellular Neuroscience, February 1996, Elsevier

    Professor Alun M Davies

  59. High Specificity of Neurotrophins in the Embryonic Chicken Trigeminal System

    Article • European Journal of Neuroscience, December 1995, Wiley

    Professor Alun M Davies

  60. GDNF is an age-specific survival factor for sensory and autonomic neurons

    Article • Neuron, October 1995, Elsevier

    Professor Alun M Davies

  61. Trigeminal Sensory Neurons Require Extrinsic Signals to Switch Neurotrophin Dependence during the Early Stages of Target Field Innervation

    Article • Developmental Biology, October 1995, Elsevier

    Professor Alun M Davies

  62. NGF Receptor Expression in Sensory Neurons Develops Normally in Embryos Lacking NGF

    Article • Developmental Biology, October 1995, Elsevier

    Professor Alun M Davies

  63. The Bcl-2 family of proteins, and the regulation of neuronal survival

    Article • Trends in Neurosciences, August 1995, Elsevier

    Professor Alun M Davies

  64. Neurotrophic Factors: Neurotrophin autocrine loops

    Article • Current Biology, July 1995, Elsevier

    Professor Alun M Davies

  65. Role of Bcl-2 in the Brain-derived Neurotrophic Factor Survival Response

    Article • European Journal of Neuroscience, June 1995, Wiley

    Professor Alun M Davies

  66. Neural Development: Chemoattractants for navigating axons

    Article • Current Biology, December 1994, Elsevier

    Professor Alun M Davies

  67. The role of neurotrophins in the developing nervous system

    Article • Journal of Neurobiology, November 1994, Wiley

    Professor Alun M Davies

  68. Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins

    Article • Neuroscience Letters, November 1994, Elsevier

    Professor Alun M Davies

  69. Localization of nerve growth factor (NGF) and low-affinity NGF receptors in touch domes and quantification of NGF mRNA in keratinocytes of adult rats

    Article • The Journal of Comparative Neurology, June 1994, Wiley

    Professor Alun M Davies

  70. Tracking neurotrophin function

    Article • Nature, March 1994, Springer Science + Business Media

    Professor Alun M Davies

  71. Neurotrophic Factors: Switching neurotrophin dependence

    Article • Current Biology, March 1994, Elsevier

    Professor Alun M Davies

  72. Intrinsic programmes of growth and survival in developing vertebrate neurons

    Article • Trends in Neurosciences, January 1994, Elsevier

    Professor Alun M Davies

  73. The role of neurotrophins during successive stages of sensory neuron development

    Article • Progress in Growth Factor Research, January 1994, Elsevier

    Professor Alun M Davies

  74. Age-related effects of nerve growth factor on the morphology of embryonic sensory neurons in vitro

    Article • The Journal of Comparative Neurology, November 1993, Wiley

    Professor Alun M Davies

  75. p75-Deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins

    Article • Neuron, October 1993, Elsevier

    Professor Alun M Davies

  76. The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis

    Article • Cell, April 1993, Elsevier

    Professor Alun M Davies

  77. Transforming growth factor-?s inhibit mitogen-stimulated proliferation of astrocytes

    Article • Glia, March 1993, Wiley

    Professor Alun M Davies

  78. Intracellular calcium regulates the survival of early sensory neurons before they become dependent on neurotrophic factors

    Article • Neuron, September 1992, Elsevier

    Professor Alun M Davies

  79. Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival

    Article • Neuron, July 1992, Elsevier

    Professor Alun M Davies

  80. The duration of neurotrophic factor independence in early sensory neurons is matched to the time course of target field innervation

    Article • Neuron, November 1991, Elsevier

    Professor Alun M Davies

  81. Nerve Growth Factor Synthesis and Nerve Growth Factor Receptor Expression in Neural Development

    Article • January 1991, Elsevier

    Professor Alun M Davies

  82. Inhibition of protein synthesis prevents cell death in sensory and parasympathetic neurons deprived of neurotrophic factorin vitro

    Article • Journal of Neurobiology, June 1990, Wiley

    Professor Alun M Davies

  83. Expression of the NGF receptor gene in sensory neurons and their cutaneous targets prior to and during innervation

    Article • Neuron, March 1990, Elsevier

    Professor Alun M Davies

  84. The Development of Primary Sensory Neurons

    Article • January 1990, Springer Science + Business Media

    Professor Alun M Davies

  85. Innervative ideas

    Article • Nature, February 1989, Springer Science + Business Media

    Professor Alun M Davies

  86. Intrinsic differences in the growth rate of early nerve fibres related to target distance

    Article • Nature, February 1989, Springer Science + Business Media

    Professor Alun M Davies

  87. Role of neurotrophic factors in development

    Article • Trends in Genetics, May 1988, Elsevier

    Professor Alun M Davies

  88. The emerging generality of the neurotrophic hypothesis

    Article • Trends in Neurosciences, January 1988, Elsevier

    Professor Alun M Davies

  89. Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor

    Article • Nature, March 1987, Springer Science + Business Media

    Professor Alun M Davies

  90. Fasciculation in the early mouse trigeminal nerve is not ordered in relation to the emerging pattern of whisker follicles

    Article • The Journal of Comparative Neurology, November 1986, Wiley

    Professor Alun M Davies

  91. Chemotropic effect of specific target epithelium in the developing mammalian nervous system

    Article • Nature, October 1986, Springer Science + Business Media

    Professor Alun M Davies

  92. The survival and growth of embryonic proprioceptive neurons is promoted by a factor present in skeletal muscle

    Article • Developmental Biology, May 1986, Elsevier

    Professor Alun M Davies

  93. Different factors from the central nervous system and periphery regulate the survival of sensory neurones

    Article • Nature, February 1986, Springer Science + Business Media

    Professor Alun M Davies

  94. The cranial sensory ganglia in culture: Differences in the response of placode-derived and neural crest-derived neurons to nerve growth factor

    Article • Developmental Biology, September 1985, Elsevier

    Professor Alun M Davies

  95. Neural crest-derived spinal and cranial sensory neurones are equally sensitive to NGF but differ in their response to tissue extracts

    Article • Developmental Brain Research, May 1984, Elsevier

    Professor Alun M Davies

  96. Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion

    Article • The Journal of Comparative Neurology, February 1984, Wiley

    Professor Alun M Davies

  97. Influence of nerve growth factor on developing dorso-medial and ventro-lateral neurons of chick and mouse trigeminal ganglia

    Article • International Journal of Developmental Neuroscience, January 1983, Elsevier

    Professor Alun M Davies