All Stories

  1. Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus

    Article • PLoS Biology, December 2021, PLOS

    Dr Florian Krammer

  2. Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model

    Article • Emerging Microbes & Infections, January 2019, Taylor & Francis

    Dr Florian Krammer

  3. Characterization of swine-origin H1N1 canine influenza viruses

    Article • Emerging Microbes & Infections, January 2019, Taylor & Francis

    Viviana Simon, Dr Florian Krammer, Dr Martha Irene Nelson

  4. Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge

    Article • Journal of Virology, June 2018, ASM Journals

    Dr Florian Krammer

  5. Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses

    Article • mSphere, May 2018, ASM Journals

    Dr Florian Krammer

  6. NAction! How Can Neuraminidase-Based Immunity Contribute to Better Influenza Virus Vaccines?

    Article • mBio, April 2018, ASM Journals

    Dr Florian Krammer

  7. Tick-Borne Encephalitis Virus Vaccine-Induced Human Antibodies Mediate Negligible Enhancement of Zika Virus Infection In Vitro and in a Mouse Model

    Article • mSphere, February 2018, ASM Journals

    Dr Florian Krammer

  8. Vaccination with a Recombinant H7 Hemagglutinin-Based Influenza Virus Vaccine Induces Broadly Reactive Antibodies in Humans

    Article • mSphere, December 2017, ASM Journals

    Dr Florian Krammer

  9. Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model

    Article • Journal of Virology, June 2017, ASM Journals

    Dr Florian Krammer

  10. Chimeric Hemagglutinin Constructs Induce Broad Protection against Influenza B Virus Challenge in the Mouse Model

    Article • Journal of Virology, March 2017, ASM Journals

    Dr Florian Krammer

  11. Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin

    Article • mBio, March 2017, ASM Journals

    Dr Florian Krammer

  12. Strategies to induce broadly protective antibody responses to viral glycoproteins

    Article • Expert Review of Vaccines, March 2017, Taylor & Francis

    Dr Florian Krammer

  13. Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans

    Article • mBio, January 2016, ASM Journals

    Dr Florian Krammer

  14. Influenza A Viruses Expressing Intra- or Intergroup Chimeric Hemagglutinins

    Article • Journal of Virology, January 2016, ASM Journals

    Dr Florian Krammer

  15. Hemagglutinin Stalk Immunity Reduces Influenza Virus Replication and Transmission in Ferrets

    Article • Journal of Virology, December 2015, ASM Journals

    Dr Florian Krammer, Dr Randy A Albrecht

  16. Hemagglutinin Stalk- and Neuraminidase-Specific Monoclonal Antibodies Protect against Lethal H10N8 Influenza Virus Infection in Mice

    Article • Journal of Virology, October 2015, ASM Journals

    Dr Florian Krammer

  17. Vaccination with Adjuvanted Recombinant Neuraminidase Induces Broad Heterologous, but Not Heterosubtypic, Cross-Protection against Influenza Virus Infection in Mice

    Article • mBio, March 2015, ASM Journals

    Dr Florian Krammer

  18. Emerging influenza viruses and the prospect of a universal influenza virus vaccine

    Article • Biotechnology Journal, March 2015, Wiley

    Dr Florian Krammer

  19. Domestic Pigs Are Susceptible to Infection with Influenza B Viruses

    Article • Journal of Virology, February 2015, ASM Journals

    Dr Florian Krammer

  20. An H10N8 influenza virus vaccine strain and mouse challenge model based on the human isolate A/Jiangxi-Donghu/346/13

    Article • Vaccine, February 2015, Elsevier

    Dr Florian Krammer

  21. Synthetic Toll-Like Receptor 4 (TLR4) and TLR7 Ligands as Influenza Virus Vaccine Adjuvants Induce Rapid, Sustained, and Broadly Protective Responses

    Article • Journal of Virology, January 2015, ASM Journals

    Dr Florian Krammer

  22. A Viable Recombinant Rhabdovirus Lacking Its Glycoprotein Gene and Expressing Influenza Virus Hemagglutinin and Neuraminidase Is a Potent Influenza Vaccine

    Article • Journal of Virology, December 2014, ASM Journals

    Dr Florian Krammer

  23. Animal Models for Influenza Viruses: Implications for Universal Vaccine Development

    Article • Pathogens, October 2014, MDPI AG

    Dr Florian Krammer

  24. Induction of Broadly Reactive Anti-Hemagglutinin Stalk Antibodies by an H5N1 Vaccine in Humans

    Article • Journal of Virology, September 2014, ASM Journals

    Dr Florian Krammer

  25. Characterization of a Broadly Neutralizing Monoclonal Antibody That Targets the Fusion Domain of Group 2 Influenza A Virus Hemagglutinin

    Article • Journal of Virology, September 2014, ASM Journals

    Dr Florian Krammer

  26. Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans

    Article • Proceedings of the National Academy of Sciences, August 2014, Proceedings of the National Academy of Sciences

    Dr Florian Krammer

  27. In the Shadow of Hemagglutinin: A Growing Interest in Influenza Viral Neuraminidase and Its Role as a Vaccine Antigen

    Article • Viruses, June 2014, MDPI AG

    Dr Florian Krammer

  28. An H7N1 Influenza Virus Vaccine Induces Broadly Reactive Antibody Responses against H7N9 in Humans

    Article • Clinical and Vaccine Immunology, June 2014, ASM Journals

    Dr Florian Krammer

  29. Divergent H7 Immunogens Offer Protection from H7N9 Virus Challenge

    Article • Journal of Virology, January 2014, ASM Journals

    Dr Florian Krammer, Dr Randy A Albrecht

  30. Assessment of Influenza Virus Hemagglutinin Stalk-Based Immunity in Ferrets

    Article • Journal of Virology, January 2014, ASM Journals

    Dr Florian Krammer, Dr Randy A Albrecht, Dr Victor H Leyva-Grado

  31. One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge

    Article • Vaccine, January 2014, Elsevier

    Dr Florian Krammer, Dr Randy A Albrecht

  32. Advances in Universal Influenza Virus Vaccine Design and Antibody Mediated Therapies Based on Conserved Regions of the Hemagglutinin

    Article • January 2014, Springer Science + Business Media

    Dr Florian Krammer

  33. Universal influenza virus vaccines: need for clinical trials

    Article • Nature Immunology, December 2013, Springer Science + Business Media

    Dr Florian Krammer

  34. H3 Stalk-Based Chimeric Hemagglutinin Influenza Virus Constructs Protect Mice from H7N9 Challenge

    Article • Journal of Virology, December 2013, ASM Journals

    Dr Florian Krammer

  35. The emergence of H7N9 viruses: a chance to redefine correlates of protection for influenza virus vaccines

    Article • Expert Review of Vaccines, December 2013, Taylor & Francis

    Dr Florian Krammer

  36. Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility

    Article • Nature Communications, December 2013, Springer Science + Business Media

    Dr Florian Krammer, Dr Victor H Leyva-Grado

  37. Expression of Functional Recombinant Hemagglutinin and Neuraminidase Proteins from the Novel H7N9 Influenza Virus Using the Baculovirus Expression System

    Article • Journal of Visualized Experiments, November 2013, MyJove Corporation

    Dr Florian Krammer

  38. Adjuvants and Immunization Strategies to Induce Influenza Virus Hemagglutinin Stalk Antibodies

    Article • PLoS ONE, November 2013, PLOS

    Dr Florian Krammer

  39. Influenza virus hemagglutinin stalk-based antibodies and vaccines

    Article • Current Opinion in Virology, October 2013, Elsevier

    Dr Florian Krammer

  40. H7N9 influenza viruses interact preferentially with  2,3-linked sialic acids and bind weakly to  2,6-linked sialic acids

    Article • Journal of General Virology, August 2013, Society for General Microbiology

    Dr Florian Krammer

  41. Neutralizing Antibodies Against Previously Encountered Influenza Virus Strains Increase over Time: A Longitudinal Analysis

    Article • Science Translational Medicine, August 2013, American Association for the Advancement of Science

    Dr Florian Krammer

  42. Hemagglutinin Stalk-Based Universal Vaccine Constructs Protect against Group 2 Influenza A Viruses

    Article • Journal of Virology, July 2013, ASM Journals

    Dr Florian Krammer, Dr Randy A Albrecht

  43. Recombinant IgA Is Sufficient To Prevent Influenza Virus Transmission in Guinea Pigs

    Article • Journal of Virology, May 2013, ASM Journals

    Dr Florian Krammer, Dr Randy A Albrecht

  44. Induction of Cross-Reactive Antibodies to Novel H7N9 Influenza Virus by Recombinant Newcastle Disease Virus Expressing a North American Lineage H7 Subtype Hemagglutinin

    Article • Journal of Virology, May 2013, ASM Journals

    Dr Florian Krammer

  45. Purification of infective baculoviruses by monoliths

    Article • Journal of Chromatography A, May 2013, Elsevier

    Dr Florian Krammer

  46. Chimeric Hemagglutinin Influenza Virus Vaccine Constructs Elicit Broadly Protective Stalk-Specific Antibodies

    Article • Journal of Virology, April 2013, ASM Journals

    Dr Florian Krammer

  47. B Cell Response and Hemagglutinin Stalk-Reactive Antibody Production in Different Age Cohorts following 2009 H1N1 Influenza Virus Vaccination

    Article • Clinical and Vaccine Immunology, April 2013, ASM Journals

    Dr Florian Krammer

  48. H3N2 Influenza Virus Infection Induces Broadly Reactive Hemagglutinin Stalk Antibodies in Humans and Mice

    Article • Journal of Virology, February 2013, ASM Journals

    Dr Florian Krammer, Dr Randy A Albrecht

  49. Residual Baculovirus in Insect Cell-Derived Influenza Virus-Like Particle Preparations Enhances Immunogenicity

    Article • PLoS ONE, December 2012, PLOS

    Dr Florian Krammer

  50. 1976 and 2009 H1N1 Influenza Virus Vaccines Boost Anti-Hemagglutinin Stalk Antibodies in Humans

    Article • The Journal of Infectious Diseases, October 2012, Oxford University Press (OUP)

    Dr Florian Krammer

  51. A Carboxy-Terminal Trimerization Domain Stabilizes Conformational Epitopes on the Stalk Domain of Soluble Recombinant Hemagglutinin Substrates

    Article • PLoS ONE, August 2012, PLOS

    Dr Florian Krammer

  52. Hemagglutinin Stalk-Reactive Antibodies Are Boosted following Sequential Infection with Seasonal and Pandemic H1N1 Influenza Virus in Mice

    Article • Journal of Virology, July 2012, ASM Journals

    Dr Florian Krammer

  53. Influenza Virus Infection in Guinea Pigs Raised as Livestock, Ecuador

    Article • Emerging Infectious Diseases, July 2012, Centers for Disease Control and Prevention (CDC)

    Dr Florian Krammer, Dr Victor H Leyva-Grado

  54. Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes

    Article • Journal of Virology, March 2012, ASM Journals

    Dr Florian Krammer, Dr Randy A Albrecht

  55. Attenuated Influenza Virus Construct with Enhanced Hemagglutinin Protein Expression

    Article • Journal of Virology, March 2012, ASM Journals

    Dr Florian Krammer

  56. Efficient Transmission of Pandemic H1N1 Influenza Viruses with High-Level Oseltamivir Resistance

    Article • Journal of Virology, February 2012, ASM Journals

    Dr Florian Krammer

  57. Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

    Article • Proceedings of the National Academy of Sciences, January 2012, Proceedings of the National Academy of Sciences

    Dr Florian Krammer

  58. Insect cells for antibody production: Evaluation of an efficient alternative

    Article • Journal of Biotechnology, May 2011, Elsevier

    Dr Florian Krammer

  59. Evaluation of the Influenza A Replicon for Transient Expression of Recombinant Proteins in Mammalian Cells

    Article • PLoS ONE, October 2010, PLOS

    Dr Florian Krammer

  60. Alternative influenza vaccines made by insect cells

    Article • Trends in Molecular Medicine, July 2010, Elsevier

    Dr Florian Krammer

  61. Influenza virus-like particles as an antigen-carrier platform for the ESAT-6 epitope of Mycobacterium tuberculosis

    Article • Journal of Virological Methods, July 2010, Elsevier

    Dr Florian Krammer

  62. Trichoplusia ni cells (High FiveTM) are highly efficient for the production of influenza A virus-like particles: a comparison of two insect cell lines as production platforms for influenza vaccines

    Article • Molecular Biotechnology, March 2010, Springer Science + Business Media

    Dr Florian Krammer

  63. Swine-origin pandemic H1N1 influenza virus-like particles produced in insect cells induce hemagglutination inhibiting antibodies in BALB/c mice

    Article • Biotechnology Journal, January 2010, Wiley

    Dr Florian Krammer