All Stories

  1. Automated Radiosynthesis and Molecular Docking Studies of Coumarin- Triazole Hybrid with fluorine-18: A feasibility study

    Article • Current Radiopharmaceuticals, March 2022, Bentham Science Publishers

    Dr Mallika Alvala, Mahammad Ghouse

  2. Targeting Integrase Enzyme: A Therapeutic Approach to Combat HIV Resistance

    Article • Mini-Reviews in Medicinal Chemistry, March 2020, Bentham Science Publishers

    Dr Mallika Alvala, Aaftaab Sethi

  3. Synthesis of Substituted Cinnamido Linked Quinazolinone Congeners as Potential Anticancer Agents via Mitochondrial Dependent Intrinsic Apoptotic Pathway

    Article • Anti-Cancer Agents in Medicinal Chemistry, January 2020, Bentham Science Publishers

    Dr Mallika Alvala

  4. Antimicrobial Peptides: A Promising Therapeutic Strategy in Tackling Antimicrobial Resistance

    Article • Current Medicinal Chemistry, December 2017, Bentham Science Publishers

    Dr Mallika Alvala

  5. Discovery of 4-sulfamoyl-phenyl-β-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors

    Article • Bioorganic & Medicinal Chemistry, January 2017, Elsevier

    Dr Mallika Alvala

  6. Identification of Small Molecule as a High Affinity β2 Agonist Promiscuously Targeting Wild and Mutated (Thr164Ile) β 2 Adrenergic Receptor in the Treatment of Bronchial Asthma

    Article • Current Pharmaceutical Design, November 2016, Bentham Science Publishers

    Dr Mallika Alvala

  7. Synthesis and biological evaluation of pyrrolo[2,3-b]pyridine analogues as antiproliferative agents and their interaction with calf thymus DNA

    Article • European Journal of Medicinal Chemistry, May 2016, Elsevier

    Dr Mallika Alvala

  8. Analysis of ADRB2 (Arg16Gly) Gene Variant with Susceptibility, Pharmacogenetic Response and Disease Severity in South Indian Asthmatics

    Article • Inflammation, June 2015, Springer Science + Business Media

    Dr Mallika Alvala

  9. Synthesis, characterization and in vitro antimicrobial evaluation of sulphonyl urea derivatives as potential inhibitors of beta-ketoacyl-acyl carrier protein synthase III (FabH)

    Article • Acta Universitaria, March 2015, University of Guanajuato

    Dr Mallika Alvala

  10. Identification of High Affinity Bioactive Salbutamol Conformer Directed Against Mutated (Thr164Ile) Beta 2 Adrenergic Receptor

    Article • Current Topics in Medicinal Chemistry, January 2015, Bentham Science Publishers

    Dr Mallika Alvala

  11. Cytotoxic constituents ofAbutilon indicumleaves against U87MG human glioblastoma cells

    Article • Natural Product Research, November 2014, Taylor & Francis

    Dr Mallika Alvala

  12. Association of Transforming Growth Factor-Beta 1 Promoter Variant -509 C/T with Bronchial Asthma in South Indian Population

    Article • Inflammation, October 2014, Springer Science + Business Media

    Dr Mallika Alvala

  13. Structure‐Guided Design of Thiazolidine Derivatives as Mycobacterium tuberculosis Pantothenate Synthetase Inhibitors

    Article • ChemMedChem, August 2014, Wiley

    Dr Mallika Alvala

  14. Structure-based drug design of small molecule SIRT1 modulators to treat cancer and metabolic disorders

    Article • Journal of Molecular Graphics and Modelling, July 2014, Elsevier

    Dr Mallika Alvala

  15. Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells

    Article • APOPTOSIS, April 2014, Springer Science + Business Media

    Dr Mallika Alvala, Dr G. Bhanuprakash Reddy

  16. Discovery and Structure Optimization of a Series of Isatin Derivatives as Mycobacterium tuberculosis Chorismate Mutase Inhibitors

    Article • Chemical Biology & Drug Design, March 2014, Wiley

    Dr Mallika Alvala

  17. Synthesis and biological evaluation of imidazo[1,5-a]pyridine-benzimidazole hybrids as inhibitors of both tubulin polymerization and PI3K/Akt pathway

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Dr Mallika Alvala

  18. Identification and characterization of novel indole based small molecules as anticancer agents through SIRT1 inhibition

    Article • European Journal of Medicinal Chemistry, November 2013, Elsevier

    Dr Mallika Alvala

  19. Identification and structure–activity relationship study of carvacrol derivatives asMycobacterium tuberculosischorismate mutase inhibitors

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, October 2013, Taylor & Francis

    Dr Mallika Alvala

  20. Scientific evidence for traditional claim of anti-obesity activity of Tecomella undulata bark

    Article • Journal of Ethnopharmacology, July 2013, Elsevier

    Dr Mallika Alvala

  21. ChemInform Abstract: Ethylenediamine Diacetate (EDDA) Mediated Synthesis of Aurones under Ultrasound: Their Evaluation as Inhibitors of SIRT1.

    Article • ChemInform, February 2013, Wiley

    Dr Mallika Alvala, Professor venkata baswesvara Rao mandava, Dr Arunasree M. Kalle

  22. Development of 5-nitrothiazole derivatives: Identification of leads against both replicative and latent Mycobacterium tuberculosis

    Article • Bioorganic & Medicinal Chemistry Letters, December 2012, Elsevier

    Dr Mallika Alvala

  23. Anticancer activity of Pupalia lappacea on chronic myeloid leukemia K562 cells

    Article • DARU Journal of Pharmaceutical Sciences, December 2012, Springer Science + Business Media

    Dr Mallika Alvala, Dr Arunasree M. Kalle

  24. Ethylenediamine diacetate (EDDA) mediated synthesis of aurones under ultrasound: Their evaluation as inhibitors of SIRT1

    Article • Bioorganic & Medicinal Chemistry Letters, October 2012, Elsevier

    Dr Mallika Alvala, Professor venkata baswesvara Rao mandava

  25. ChemInform Abstract: Novel Acridinedione Derivatives: Design, Synthesis, SIRT1 Enzyme and Tumor Cell Growth Inhibition Studies.

    Article • ChemInform, August 2012, Wiley

    Dr Mallika Alvala

  26. Can targeting SIRT-1 to treat type 2 diabetes be a good strategy? A review

    Article • Expert Opinion on Therapeutic Targets, July 2012, Informa Healthcare

    Dr Mallika Alvala

  27. Novel acridinedione derivatives: Design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies

    Article • Bioorganic & Medicinal Chemistry Letters, May 2012, Elsevier

    Dr Mallika Alvala

  28. Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Dr Mallika Alvala

  29. Synthesis and In Vitro antiproliferative activity of 2-methyl-3-(2-piperazin-1-yl-ethyl)-pyrido[1,2-a]pyrimidin-4-one derivatives against human cancer cell lines

    Article • Archives of Pharmacal Research, January 2012, Springer Science + Business Media

    Dr Mallika Alvala

  30. Antiproliferative activity and standardization of Tecomella undulata bark extract on K562 cells

    Article • Journal of Ethnopharmacology, October 2011, Elsevier

    Dr Mallika Alvala

  31. ChemInform Abstract: Sequential Coupling/Desilylation—Coupling/Cyclization in a Single Pot under Pd/C—Cu Catalysis: Synthesis of 2‐(Hetero)aryl Indoles.

    Article • ChemInform, September 2011, Wiley

    Dr Mallika Alvala

  32. Synthesis of various 3-nitropropionamides as Mycobacterium tuberculosis isocitrate lyase inhibitor

    Article • Bioorganic & Medicinal Chemistry Letters, September 2011, Elsevier

    Dr Mallika Alvala

  33. ChemInform Abstract: Transition Metal Mediated Construction of Pyrrole Ring on 2,3‐Dihydroquinolin‐4(1H)‐one: Synthesis and Pharmacological Evaluation of Novel Tricyclic Heteroarenes.

    Article • ChemInform, May 2011, Wiley

    Dr Mallika Alvala

  34. Sequential coupling/desilylation–coupling/cyclization in a single pot under Pd/C–Cu catalysis: Synthesis of 2-(hetero)aryl indoles

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    Dr Mallika Alvala

  35. Transition metal mediated construction of pyrrole ring on 2,3-dihydroquinolin-4(1H)-one: synthesis and pharmacological evaluation of novel tricyclic heteroarenes

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    Dr Mallika Alvala