All Stories

  1. Current insights in the complexities underlying drug-induced cholestasis

    Article • Critical Reviews in Toxicology, July 2019, Taylor & Francis

    Dr Pieter P Annaert

  2. Non-clinical Models to Determine Drug Passage into Human Breast Milk

    Article • Current Pharmaceutical Design, June 2019, Bentham Science Publishers

    Dr Pieter P Annaert

  3. Drug-induced cholestasis mechanisms

    Article • Current Drug Metabolism, September 2018, Bentham Science Publishers

    Dr Pieter P Annaert

  4. MRP2 Inhibition by HIV Protease Inhibitors in Rat and Human Hepatocytes: A Quantitative Confocal Microscopy Study

    Article • Drug Metabolism and Disposition, March 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Pieter P Annaert

  5. Transport-Metabolism Interplay of Atazanavir in Rat Hepatocytes

    Article • Drug Metabolism and Disposition, December 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Pieter P Annaert

  6. Effect of Age on The Hepatocellularity Number for Wistar rats

    Article • Drug Metabolism and Disposition, December 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Pieter P Annaert

  7. Unbound Ritonavir Concentrations in Rat and Human Hepatocytes

    Article • Journal of Pharmaceutical Sciences, July 2015, Elsevier

    Dr Pieter P Annaert, Janneke Keemink

  8. Drug-induced cholestasis detection in cryopreserved rat hepatocytes in sandwich culture

    Article • Journal of Pharmacological and Toxicological Methods, May 2015, Elsevier

    Dr Pieter P Annaert

  9. Primary Hepatocytes in Sandwich Culture

    Article • November 2014, Springer Science + Business Media

    Dr Pieter P Annaert

  10. Age-Dependent Activity of the Uptake Transporters Ntcp and Oatp1b2 in Male Rat Hepatocytes: From Birth Till Adulthood

    Article • Drug Metabolism and Disposition, October 2014, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Pieter P Annaert

  11. Intramuscular Administration of Paliperidone Palmitate Extended-Release Injectable Microsuspension Induces a Subclinical Inflammatory Reaction Modulating the Pharmacokinetics in Rats

    Article • Journal of Pharmaceutical Sciences, July 2014, Elsevier

    Dr Pieter P Annaert

  12. Bile acid disposition by confocal microscopy

    Article • Journal of Pharmaceutical Sciences, June 2014, Elsevier

    Dr Pieter P Annaert, Bruno Stieger

  13. Toxicity and intracellular accumulation of bile acids in sandwich-cultured rat hepatocytes: Role of glycine conjugates

    Article • Toxicology in Vitro, March 2014, Elsevier

    Dr Pieter P Annaert

  14. Hepatocyte-based in vitro model for assessment of drug-induced cholestasis

    Article • Toxicology and Applied Pharmacology, January 2014, Elsevier

    Dr Pieter P Annaert

  15. Drug disposition and clinical practice in neonates: Cross talk between developmental physiology and pharmacology

    Article • International Journal of Pharmaceutics, August 2013, Elsevier

    Professor karel allegaert , Dr Pieter P Annaert

  16. Sandwich-cultured hepatocytes: utility forin vitroexploration of hepatobiliary drug disposition and drug-induced hepatotoxicity

    Article • Expert Opinion on Drug Metabolism & Toxicology, March 2013, Informa Healthcare

    Dr Pieter P Annaert

  17. Nonclinical Testing Procedures—Pharmacokinetics

    Article • January 2012, Wiley

    Dr Pieter P Annaert

  18. Sodium fluorescein is a probe substrate for hepatic drug transport mediated by OATP1B1 and OATP1B3

    Article • Journal of Pharmaceutical Sciences, November 2011, Elsevier

    Dr Pieter P Annaert, Bruno Stieger

  19. Influence of Drug Transport Proteins on the Pharmacokinetics and Drug Interactions of Hiv Protease Inhibitors

    Article • Journal of Pharmaceutical Sciences, September 2011, Elsevier

    Dr Pieter P Annaert

  20. Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes

    Article • European Journal of Pharmaceutical Sciences, July 2011, Elsevier

    Dr Pieter P Annaert

  21. Higher clearance of micafungin in neonates compared with adults: role of age‐dependent micafungin serum binding

    Article • Biopharmaceutics & Drug Disposition, March 2011, Wiley

    Dr Pieter P Annaert

  22. Species-Specific Interaction of HIV Protease Inhibitors With Accumulation of Cholyl-Glycylamido-Fluorescein (CGamF) in Sandwich-Cultured Hepatocytes

    Article • Journal of Pharmaceutical Sciences, June 2010, Elsevier

    Dr Pieter P Annaert

  23. Interaction of eight HIV protease inhibitors with the canalicular efflux transporter ABCC2 (MRP2) in sandwich‐cultured rat and human hepatocytes

    Article • Biopharmaceutics & Drug Disposition, March 2010, Wiley

    Dr Pieter P Annaert

  24. Drug Transport in the Liver

    Article • November 2006, Wiley

    Dr Pieter P Annaert

  25. Cell-based models to study hepatic drug metabolism and enzyme induction in humans

    Article • Expert Opinion on Drug Metabolism & Toxicology, June 2005, Informa Healthcare

    Dr Pieter P Annaert

  26. In Vitro, Ex Vivo, and In Situ Intestinal Absorption Characteristics of the Antiviral Ester Prodrug Adefovir Dipivoxil

    Article • Journal of Pharmaceutical Sciences, August 2000, Elsevier

    Dr Pieter P Annaert

  27. Hydration Changes Implicated in the Remarkable Temperature-Dependent Membrane Permeation of Cyclosporin A

    Article • Biochemistry, June 2000, American Chemical Society (ACS)

    Dr Pieter P Annaert