All Stories

  1. Soybean (Glycine max) Is Able to Absorb, Metabolize and Accumulate Fenbendazole in All Organs Including Beans

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Dr Barbora Szotakova

  2. Leaves and Fruits Preparations of Pistacia lentiscus L.: A Review on the Ethnopharmacological Uses and Implications in Inflammation and Infection

    Article • Antibiotics, April 2021, MDPI AG

    Dr Barbora Szotakova

  3. <em>Pistacia lentiscus</em>: From Phytopharmacology to Scientific Explanations on Its Anti-Inflammatory and Antimicrobial Capacity

    Article • February 2021, MDPI AG

    Dr Barbora Szotakova

  4. The Identification of Metabolites and Effects of Albendazole in Alfalfa (Medicago sativa)

    Article • International Journal of Molecular Sciences, August 2020, MDPI AG

    Dr Barbora Szotakova

  5. The Uptake of Ivermectin and Its Effects in Roots, Leaves and Seeds of Soybean (Glycine max)

    Article • Molecules, August 2020, MDPI AG

    Dr Barbora Szotakova

  6. The Modulation of Phase II Drug-Metabolizing Enzymes in Proliferating and Differentiated CaCo-2 Cells by Hop-Derived Prenylflavonoids

    Article • Nutrients, July 2020, MDPI AG

    Dr Barbora Szotakova

  7. The Pharmaceutical Ability of Pistacia lentiscus L. Leaves Essential Oil Against Periodontal Bacteria and Candida sp. and Its Anti-Inflammatory Potential

    Article • Antibiotics, May 2020, MDPI AG

    Dr Barbora Szotakova

  8. The Pharmaceutical Ability of <em>Pistacia lentiscus</em> L. Leaves Essential Oil against Periodontal Bacteria and Candida sp. and Its Anti-inflammatory Potential

    Article • May 2020, MDPI AG

    Dr Barbora Szotakova

  9. Ivermectin biotransformation and impact on transcriptome in Arabidopsis thaliana

    Article • Chemosphere, November 2019, Elsevier

    Dr Barbora Szotakova

  10. Ivermectin environmental impact: Excretion profile in sheep and phytotoxic effect in Sinapis alba

    Article • Ecotoxicology and Environmental Safety, March 2019, Elsevier

    Dr Barbora Szotakova

  11. Biotransformation of flubendazole and fenbendazole and their effects in the ribwort plantain (Plantago lanceolata)

    Article • Ecotoxicology and Environmental Safety, January 2018, Elsevier

    Dr Barbora Szotakova

  12. The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro

    Article • Chemico-Biological Interactions, December 2017, Elsevier

    Dr Barbora Szotakova

  13. Sulforaphane Alters β-Naphthoflavone-Induced Changes in Activity and Expression of Drug-Metabolizing Enzymes in Rat Hepatocytes

    Article • Molecules, November 2017, MDPI AG

    Dr Barbora Szotakova

  14. Evaluation of drug uptake and deactivation in plant: Fate of albendazole in ribwort plantain (Plantago laceolata) cells and regenerants

    Article • Ecotoxicology and Environmental Safety, July 2017, Elsevier

    Dr Barbora Szotakova

  15. Design, Synthesis, and Biological Evaluation of Isothiosemicarbazones with Antimycobacterial Activity

    Article • Archiv der Pharmazie, June 2017, Wiley

    Dr Barbora Szotakova

  16. Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions

    Article • Molecules, March 2017, MDPI AG

    Dr Barbora Szotakova

  17. Effect of Green Tea Extract-Enriched Diets on Insulin and Leptin Levels, Oxidative Stress Parameters and Antioxidant Enzymes Activities in Obese Mice

    Article • Polish Journal of Food and Nutrition Sciences, January 2017, De Gruyter

    Dr Barbora Szotakova

  18. Catechins Variously Affect Activities of Conjugation Enzymes in Proliferating and Differentiated Caco-2 Cells

    Article • Molecules, September 2016, MDPI AG

    Dr Barbora Szotakova

  19. Metabolic pathways of benzimidazole anthelmintics in harebell (Campanula rotundifolia)

    Article • Chemosphere, August 2016, Elsevier

    Dr Barbora Szotakova

  20. Albendazole in environment: faecal concentrations in lambs and impact on lower development stages of helminths and seed germination

    Article • Environmental Science and Pollution Research, March 2016, Springer Science + Business Media

    Dr Barbora Szotakova

  21. Cranberry extract–enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice

    Article • Nutrition Research, October 2015, Elsevier

    Dr Barbora Szotakova

  22. The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells

    Article • Molecules, August 2015, MDPI AG

    Dr Barbora Szotakova

  23. Metabolism of drugs and other xenobiotics in giant liver fluke (Fascioloides magna)

    Article • Xenobiotica, July 2015, Taylor & Francis

    Dr Barbora Szotakova

  24. Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus

    Article • Molecular and Biochemical Parasitology, June 2015, Elsevier

    Dr Barbora Szotakova

  25. Comparison of biotransformation and efficacy of aminoacetonitrile anthelmintics in vitro

    Article • Drug Testing and Analysis, April 2015, Wiley

    Dr Barbora Szotakova

  26. Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo

    Article • Acta Pharmaceutica, March 2015, De Gruyter

    Dr Barbora Szotakova

  27. Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity

    Article • European Journal of Nutrition, February 2015, Springer Science + Business Media

    Dr Barbora Szotakova

  28. Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo

    Article • Chemico-Biological Interactions, February 2015, Elsevier

    Dr Barbora Szotakova

  29. Drug-Metabolizing and Antioxidant Enzymes in Monosodium L-Glutamate Obese Mice

    Article • Drug Metabolism and Disposition, December 2014, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Petra Matouskova, Dr Barbora Szotakova

  30. Biotransformation of anthelmintics in tapeworm Moniezia expansa

    Article • Parasitology, November 2014, Cambridge University Press

    Dr Barbora Szotakova

  31. Characterization of Tetratricopeptide Repeat-Like Proteins in Francisella tularensis and Identification of a Novel Locus Required for Virulence

    Article • Infection and Immunity, September 2014, ASM Journals

    Dr Barbora Szotakova

  32. Effect of Standardized Cranberry Extract on the Activity and Expression of Selected Biotransformation Enzymes in Rat Liver and Intestine

    Article • Molecules, September 2014, MDPI AG

    Dr Barbora Szotakova

  33. Effect of defined green tea extract in various dosage schemes on drug-metabolizing enzymes in mice in vivo

    Article • Journal of Functional Foods, September 2014, Elsevier

    Dr Barbora Szotakova

  34. Metabolic pathways of anthelmintic drug monepantel in sheep and in its parasite (Haemonchus contortus)

    Article • Drug Testing and Analysis, March 2014, Wiley

    Dr Barbora Szotakova

  35. Reference Genes for Real-Time PCR Quantification of Messenger RNAs and MicroRNAs in Mouse Model of Obesity

    Article • PLoS ONE, January 2014, PLOS

    Dr Barbora Szotakova

  36. Francisella tularensis subsp. holarctica DsbA homologue: a thioredoxin-like protein with chaperone function

    Article • Microbiology, November 2013, Society for General Microbiology

    Dr Barbora Szotakova

  37. Biotransformation of albendazole and activities of selected detoxification enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics

    Article • Veterinary Parasitology, September 2013, Elsevier

    Dr Barbora Szotakova

  38. Biotransformation of benzimidazole anthelmintics in reed (Phragmites australis) as a potential tool for their detoxification in environment

    Article • Bioresource Technology, September 2013, Elsevier

    Dr Barbora Szotakova

  39. Analytical power of LLE–HPLC–PDA–MS/MS in drug metabolism studies: Identification of new nabumetone metabolites

    Article • Journal of Pharmaceutical and Biomedical Analysis, June 2013, Elsevier

    Professor Thomas Jira, Dr Barbora Szotakova

  40. Inhibitory effect of anthocyanidins on hepatic glutathione S-transferase, UDP-glucuronosyltransferase and carbonyl reductase activities in rat and human

    Article • Xenobiotica, January 2013, Taylor & Francis

    Dr Barbora Szotakova

  41. Age-Related Changes in Hepatic Activity and Expression of Detoxification Enzymes in Male Rats

    Article • BioMed Research International, January 2013, Hindawi Publishing Corporation

    Dr Barbora Szotakova

  42. Investigation of the metabolism of monepantel in ovine hepatocytes by UHPLC/MS/MS

    Article • Analytical and Bioanalytical Chemistry, November 2012, Springer Science + Business Media

    Dr Barbora Szotakova

  43. The metabolic fate of ivermectin in host (Ovis aries) and parasite (Haemonchus contortus)

    Article • Parasitology, October 2012, Cambridge University Press

    Dr Barbora Szotakova

  44. Import and efflux of flubendazole in Haemonchus contortus strains susceptible and resistant to anthelmintics

    Article • Veterinary Parasitology, July 2012, Elsevier

    Dr Barbora Szotakova

  45. The metabolism of flubendazole and the activities of selected biotransformation enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics

    Article • Parasitology, May 2012, Cambridge University Press

    Dr Barbora Szotakova

  46. The inability of tapeworm Hymenolepis diminuta and fluke Dicrocoelium dendriticum to metabolize praziquantel

    Article • Veterinary Parasitology, April 2012, Elsevier

    Dr Barbora Szotakova

  47. The activity of drug-metabolizing enzymes and the biotransformation of selected anthelmintics in the model tapeworm Hymenolepis diminuta

    Article • Parasitology, February 2012, Cambridge University Press

    Dr Barbora Szotakova

  48. High-performance liquid chromatographic determination of tiapride and its phase I metabolite in blood plasma using tandem UV photodiode-array and fluorescence detection

    Article • Journal of Chromatography B, December 2011, Elsevier

    Dr Barbora Szotakova

  49. The transport of albendazole and albendazole sulphoxide in the lancet fluke (Dicrocoelium dendriticum)

    Article • Veterinary Parasitology, February 2011, Elsevier

    Dr Barbora Szotakova

  50. The effects of flubendazole and its metabolites on the larval development of Haemonchus contortus (Nematoda: Trichostrongylidae): an in vitro study

    Article • Helminthologia, December 2010, De Gruyter

    Dr Barbora Szotakova

  51. Effect of Flubendazole on Biotransformation Enzymes Activities in Haemonchus contortus~!2010-03-18~!2010-06-16~!2010-08-07~!

    Article • The Open Parasitology Journal, August 2010, Bentham Science Publishers

    Dr Barbora Szotakova

  52. In vitrooxidative metabolism of xenobiotics in the lancet fluke (Dicrocoelium dendriticum) and the effects of albendazole and albendazole sulphoxideex vivo

    Article • Xenobiotica, June 2010, Taylor & Francis

    Dr Barbora Szotakova

  53. Activities of biotransformation enzymes and flubendazole metabolism in lambs (Ovis aries): effect of gender and flubendazole therapy

    Article • Pharmacological Reports, March 2010, Springer Science + Business Media

    Dr Barbora Szotakova

  54. Flubendazole metabolism and biotransformation enzymes activities in healthy sheep and sheep with haemonchosis

    Article • Journal of Veterinary Pharmacology and Therapeutics, February 2010, Wiley

    Dr Barbora Szotakova

  55. Liquid chromatography/mass spectrometric identification of benzimidazole anthelminthics metabolites formed ex vivo by Dicrocoelium dendriticum

    Article • Rapid Communications in Mass Spectrometry, July 2009, Wiley

    Dr Barbora Szotakova

  56. Phase I biotransformation of albendazole in lancet fluke (Dicrocoelium dendriticum)

    Article • Research in Veterinary Science, February 2009, Elsevier

    Dr Barbora Szotakova

  57. Sensitive chiral high-performance liquid chromatographic determination of anthelmintic flubendazole and its phase I metabolites in blood plasma using UV photodiode-array and fluorescence detection

    Article • Journal of Chromatography B, December 2008, Elsevier

    Dr Barbora Szotakova

  58. LC with Fluorimetric Detection for Sensitive Analysis of Reduced Flubendazole in Biological Samples

    Article • Chromatographia, September 2008, Springer Science + Business Media

    Dr Barbora Szotakova

  59. LC–MS–MS identification of albendazole and flubendazole metabolites formed ex vivo by Haemonchus contortus

    Article • Analytical and Bioanalytical Chemistry, March 2008, Springer Science + Business Media

    Dr Barbora Szotakova

  60. Biotransformation of flubendazole and selected model xenobiotics in Haemonchus contortus

    Article • Veterinary Parasitology, February 2008, Elsevier

    Dr Barbora Szotakova

  61. Modulation of Porcine (Sus scrofa domestica) and Pheasant (Phasianus colchicus) Carbonyl Reducing Enzymes by Anthelmintic Therapy with Flubendazole

    Article • Drug Metabolism Letters, January 2008, Bentham Science Publishers

    Dr Barbora Szotakova

  62. Aldo-keto reductases (AKR) from the AKR1C subfamily catalyze the carbonyl reduction of the novel anticancer drug oracin in man

    Article • Toxicology, September 2007, Elsevier

    Dr Barbora Szotakova

  63. Activities of biotransformation enzymes in pheasant (Phasianus colchicus) and their modulation by in vivo administration of mebendazole and flubendazole

    Article • Research in Veterinary Science, August 2007, Elsevier

    Dr Barbora Szotakova

  64. Achiral and chiral high-performance liquid chromatographic determination of flubendazole and its metabolites in biomatrices using UV photodiode-array and mass spectrometric detection

    Article • Journal of Chromatography A, May 2007, Elsevier

    Professor Thomas Jira, Dr Barbora Szotakova

  65. Mouflon (Ovis musimon) dicrocoeliosis: Effects of parasitosis on the activities of biotransformation enzymes and albendazole metabolism in liver

    Article • Veterinary Parasitology, May 2007, Elsevier

    Dr Barbora Szotakova

  66. Modulation of porcine biotransformation enzymes by anthelmintic therapy with fenbendazole and flubendazole

    Article • Research in Veterinary Science, June 2006, Elsevier

    Dr Barbora Szotakova

  67. The effects of flubendazole and mebendazole on cytochromes P4501A in pheasant hepatocytes

    Article • Research in Veterinary Science, October 2005, Elsevier

    Dr Barbora Szotakova

  68. Liver microsomal biotransformation of albendazole in deer, cattle, sheep and pig and some related wild breeds

    Article • Journal of Veterinary Pharmacology and Therapeutics, July 2005, Wiley

    Dr Barbora Szotakova

  69. Albendazole repeated administration induces cytochromes P4501A and accelerates albendazole deactivation in mouflon (Ovis musimon)

    Article • Research in Veterinary Science, June 2005, Elsevier

    Dr Barbora Szotakova

  70. Use of chiral liquid chromatography for the evaluation of stereospecificity in the carbonyl reduction of potential benzo[c]fluorene antineoplastics benfluron and dimefluron in various species

    Article • Journal of Pharmaceutical and Biomedical Analysis, April 2005, Elsevier

    Dr Barbora Szotakova

  71. The stereoselective biotransformation of the anti-obesity drug sibutramine in rat liver microsomes and in primary cultures of rat hepatocytes

    Article • Journal of Pharmacy and Pharmacology, March 2005, Oxford University Press (OUP)

    Dr Barbora Szotakova

  72. Chiral Inversion of Drugs: Coincidence or Principle?

    Article • Current Drug Metabolism, December 2004, Bentham Science Publishers

    Dr Barbora Szotakova

  73. The effects of fenbendazole, flubendazole and mebendazole on activities of hepatic cytochromes P450 in pig

    Article • Journal of Veterinary Pharmacology and Therapeutics, April 2004, Wiley

    Dr Barbora Szotakova

  74. Characterization of enzymes responsible for biotransformation of the new antileukotrienic drug quinlukast in rat liver microsomes and in primary cultures of rat hepatocytes

    Article • Journal of Pharmacy and Pharmacology, February 2004, Oxford University Press (OUP)

    Dr Barbora Szotakova

  75. Comparison of in vitro activities of biotransformation enzymes in pig, cattle, goat and sheep

    Article • Research in Veterinary Science, February 2004, Elsevier

    Dr Barbora Szotakova

  76. The Phase I Biotransformation of the Potential Antileukotrienic Drug Quinlukast in Rat Microsomes and Hepatocytes

    Article • Collection of Czechoslovak Chemical Communications, January 2004, Institute of Organic Chemistry & Biochemistry

    Dr Barbora Szotakova

  77. Stereospecificity of flobufen metabolism in guinea pigs in vitro and in vivo: Phase I of biotransformation

    Article • Chirality, October 2003, Wiley

    Dr Barbora Szotakova

  78. Inter-species comparisons of hepatic cytochrome P450 enzyme levels in male ruminants

    Article • Archives of Toxicology, October 2003, Springer Science + Business Media

    Dr Barbora Szotakova

  79. Stereospecific biotransformation of albendazole in mouflon and rat‐isolated hepatocytes

    Article • Journal of Veterinary Pharmacology and Therapeutics, July 2003, Wiley

    Dr Barbora Szotakova

  80. Stereospecific reduction of the original anticancer drug oracin in rat extrahepatic tissues

    Article • Journal of Pharmacy and Pharmacology, July 2003, Oxford University Press (OUP)

    Dr Barbora Szotakova

  81. Chiral aspects of metabolism of antiinflammatory drug flobufen in human hepatocytes

    Article • Chirality, January 2003, Wiley

    Dr Barbora Szotakova

  82. Reduction of flobufen in pig hepatocytes: Effect of pig breed (domestic, wild) and castration

    Article • Chirality, January 2003, Wiley

    Dr Barbora Szotakova

  83. Article • BMC Pharmacology, January 2003, Springer Science + Business Media

    Dr Barbora Szotakova

  84. Carbonyl reduction of the potential cytostatic drugs benfluron and 3,9-dimethoxybenfluron in human in vitro

    Article • Biochemical Pharmacology, July 2002, Elsevier

    Dr Barbora Szotakova

  85. Biotransformation of flobufen enantiomers in ruminant hepatocytes and subcellular fractions

    Article • Chirality, January 2001, Wiley

    Dr Barbora Szotakova

  86. Stereospecificity and stereoselectivity of flobufen metabolic profile in male rats in vitro and in vivo: Phase I of biotransformation

    Article • Chirality, January 2001, Wiley

    Dr Barbora Szotakova

  87. Effect of substituents on microsomal reduction of benzo(c)fluorene N-oxides

    Article • Chemico-Biological Interactions, June 2000, Elsevier

    Dr Barbora Szotakova

  88. Reduction of the Potential Anticancer Drug Oracin in the Rat Liver In-vitro

    Article • Journal of Pharmacy and Pharmacology, May 2000, Oxford University Press (OUP)

    Dr Barbora Szotakova

  89. Activity, stereospecificity, and stereoselectivity of microsomal enzymes in dependence on storage and freezing of rat liver samples

    Article • Chirality, January 2000, Wiley

    Dr Barbora Szotakova

  90. A comparison between stereospecificity of oracin reduction and stereoselectivity of oxidation of 11-dihydrooracin enantiomersin vitro in rat and guinea pig

    Article • Chirality, January 1999, Wiley

    Dr Barbora Szotakova

  91. Sex differences in stereospecificity of oracin reductases in ratin vitro andin vivo

    Article • Chirality, January 1999, Wiley

    Dr Barbora Szotakova

  92. Stereoselective pharmacokinetics of flobufen in rats

    Article • Chirality, January 1999, Wiley

    Dr Barbora Szotakova

  93. High-performance liquid chromatography study of stereospecific microsomal enzymes catalysing the reduction of a potential cytostatic drug, oracin

    Article • Journal of Chromatography A, February 1998, Elsevier

    Dr Barbora Szotakova

  94. High-performance liquid chromatographic assay for the separation and characterization of metabolites of the potential cytostatic drug oracine

    Article • Journal of Chromatography B Biomedical Sciences and Applications, May 1996, Elsevier

    Dr Barbora Szotakova