All Stories

  1. Does Supramolecular Gelation Require an External Trigger?
  2. De-risking S–F bond formation: A gas cylinder-free strategy to access S(IV) and S(VI) fluorinated compounds.
  3. Cryogenic contrast-enhanced microCT enables nondestructive 3D quantitative histopathology of soft biological tissues
  4. 3-Methyl 5-{3-[(4-Methylbenzenesulfonyl)oxy]propyl} 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
  5. Chemistry of Pentafluorosulfanyl Derivatives and Related Analogs: From Synthesis to Applications
  6. From the North Sea to Drug Repurposing, the Antiseizure Activity of Halimide and Plinabulin
  7. Carbonylation Chemistry Applied to the Synthesis of Benzimidazo[2,1‐ b ]quinazolin‐12‐ones
  8. 1,3-Diazepines
  9. Penicillins
  10. SuFEx-enabled, chemoselective synthesis of triflates, triflamides and triflimidates
  11. Correction: SuFEx-enabled, chemoselective synthesis of triflates, triflamides and triflimidates
  12. Characterization of Microbial Degradation Products of Steviol Glycosides
  13. Can the Philicity of Radicals Be Influenced by Oriented External Electric Fields?
  14. LSA-50 paper: An alternative to P81 phosphocellulose paper for radiometric protein kinase assays
  15. Computational Tools to Rationalize and Predict the Self-Assembly Behavior of Supramolecular Gels
  16. Frontispiece: Lighting Up the Plasma Membrane: Development and Applications of Fluorescent Ligands for Transmembrane Proteins
  17. Bioassay-guided isolation of antibacterial compounds from the leaves of Tetradenia riparia with potential bactericidal effects on food-borne pathogens
  18. Lighting Up the Plasma Membrane: Development and Applications of Fluorescent Ligands for Transmembrane Proteins
  19. Developments in the Discovery and Design of Protein Kinase D Inhibitors
  20. Copper(0) nanoparticle catalyzed Z ‐Selective Transfer Semihydrogenation of Internal Alkynes
  21. The presence of benzophenone in sunscreens and cosmetics containing the organic UV filter octocrylene: A laboratory study
  22. Solvent-free N-Boc deprotection by ex situ generation of hydrogen chloride gas
  23. Ultrasmall iron oxide nanoparticles functionalized with BODIPY derivatives as potential bimodal probes for MRI and optical imaging
  24. Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyrimidine-based protein kinase D inhibitors
  25. Concomitant positive patch test reactions in FreeStyle‐allergic patients sensitized to isobornyl acrylate
  26. Facile Method to Obtain Low DS β-ketoesters and Esters of Microfibrillated Cellulose
  27. Nematicidal Activity of Holigarna caustica (Dennst.) Oken Fruit Is Due to Linoleic Acid
  28. Tuning the Properties of Polyether Alkyl Urea Derivatives as Rheology Modifiers in Cosmetic Solvents
  29. Stereoselective Reductions of 3-Substituted Cyclobutanones: A Comparison between Experiment and Theory
  30. Biofilm inhibiting properties of compounds from the leaves of Warburgia ugandensis Sprague subsp ugandensis against Candida and staphylococcal biofilms
  31. Exploring polyoxometalates as non-destructive staining agents for contrast-enhanced microfocus computed tomography of biological tissues
  32. Ex situ gas generation for lab scale organic synthesis
  33. Molecular dynamics based descriptors for predicting supramolecular gelation
  34. Rationalising Supramolecular Hydrogelation of Bis‐Urea‐Based Gelators through a Multiscale Approach
  35. Rationalising Supramolecular Hydrogelation of Bis‐Urea‐Based Gelators through a Multiscale Approach
  36. Rationalising Supramolecular Hydrogelation of Bis‐Urea‐Based Gelators through a Multiscale Approach
  37. Introduction of Aryl Fluorosulfates into the Realm of Catellani Reaction Substrates
  38. Green approach for the activation and functionalization of jute fibers through ball milling
  39. Modeling of Nanomolecular and Reticular Architectures with 6-fold Grooved, Programmable Interlocking Disks
  40. Nanocarrier systems assembled from PEGylated hyperbranched poly(arylene oxindole)
  41. Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily
  42. An Effective and Reusable Hyperbranched Polymer Immobilized Rhodium Catalyst for the Hydroformylation of Olefins
  43. Electrochemistry and Photoredox Catalysis: A Comparative Evaluation in Organic Synthesis
  44. Ketone Synthesis by a Nickel-Catalyzed Dehydrogenative Cross-Coupling of Primary Alcohols
  45. Synthesis of N-Acyl Sulfamates from Fluorosulfates and Amides
  46. Ball milling: a green technology for the preparation and functionalisation of nanocellulose derivatives
  47. Robust scalable synthesis of a bis-urea derivative forming thixotropic and cytocompatible supramolecular hydrogels
  48. Chemical structure and biological properties of sulfated fucan from the sequential extraction of subAntarctic Lessonia sp (Phaeophyceae)
  49. Bioassay-guided isolation of active substances from Semen Torreyae identifies two new anthelmintic compounds with novel mechanism of action
  50. A Robust and Scalable Continuous Flow Process for Glycerol Carbonate
  51. Bioassay-guided isolation of three anthelmintic compounds from Warburgia ugandensis Sprague subspecies ugandensis, and the mechanism of action of polygodial
  52. Identification of fukinolic acid from Cimicifuga heracleifolia and its derivatives as novel antiviral compounds against enterovirus A71 infection
  53. Direct Access to Aryl Bis(trifluoromethyl)carbinols from Aryl Bromides or Fluorosulfates: Palladium-Catalyzed Carbonylation
  54. Direct Access to Aryl Bis(trifluoromethyl)carbinols from Aryl Bromides or Fluorosulfates: Palladium-Catalyzed Carbonylation
  55. Active principles of Tetradenia riparia . IV. Anthelmintic activity of 8(14),15-sandaracopimaradiene-7α,18-diol
  56. Non-innocent probes in direct sonication: Metal assistance in oxidative radical C H functionalization
  57. Methylated flavonoids as anti-seizure agents: Naringenin 4′,7-dimethyl ether attenuates epileptic seizures in zebrafish and mouse models
  58. Synthesis and peptide functionalization of hyperbranched poly(arylene oxindole) towards versatile biomaterials
  59. Synthesis of an IS and Steviol Glycoside Analysis by a Validated Internal Standard Method
  60. Flow-Assisted Synthesis of Heterocycles via Multicomponent Reactions
  61. Functionalization of Heteroarenes Under Continuous Flow
  62. Water Tolerant and Reusable Sulfonated Hyperbranched Poly(aryleneoxindole) Acid Catalyst for Solvent-Free Esterification
  63. Ex Situ Generation of Sulfuryl Fluoride for the Synthesis of Aryl Fluorosulfates
  64. A Convenient Multigram Synthesis of DABSO Using Sodium Sulfite as SO2 Source
  65. Crystal structure of 5-benzyl-8-bromo-2-methyl-1,3-oxazolo[4,5-c][1,8]naphthyridin-4(5H)-one
  66. Towards New Tricyclic Motifs: Intramolecular C-H Arylation as the Key Step in a Formal [3+3] Cyclocondensation Strategy
  67. Intramolecular Carbonylative C-H Functionalization of 1,2,3- Triazoles for the Synthesis of Triazolo[1,5-a]indolones
  68. Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo[3,4-d]pyrimidine analogues
  69. Carbonylation as a novel method for the assembly of pyrazine based oligoamide alpha-helix mimetics
  70. Nanocellulosic materials as bioinks for 3D bioprinting
  71. The orthorhombic pseudopolymorph of tacrine hydrochloride
  72. Low-cost instant CO generation at room temperature using formic acid, mesyl chloride and triethylamine
  73. Gadolinium(III)-DOTA Complex Functionalized with BODIPY as a Potential Bimodal Contrast Agent for MRI and Optical Imaging
  74. Luminescence and Relaxometric Properties of Heteropolymetallic Metallostar Complexes with Selectively Incorporated Lanthanide(III) Ions
  75. Improved detection of β-N-methylamino-l-alanine using N-hydroxysuccinimide ester of N-butylnicotinic acid for the localization of BMAA in blue mussels (Mytilus edulis)
  76. Synthesis of N -Hydroxypyrazin-2(1 H )-ones via Selective O -Debenzylation of 1-Benzyloxypyrazin-2(1 H )-ones Using Flow Methodology
  77. First Example of Alkyl–Aryl Negishi Cross-Coupling in Flow: Mild, Efficient and Clean Introduction of Functionalized Alkyl Groups
  78. Facile azide formation via diazotransfer reaction in a copper tube flow reactor
  79. The Zeamine Antibiotics Affect the Integrity of Bacterial Membranes
  80. First Example of a Continuous-Flow Carbonylation Reaction Using Aryl Formates as CO Precursors
  81. Synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives
  82. Synthesis of 11-aza-artemisinin derivatives using the Ugi reaction and an evaluation of their antimalarial activity
  83. Synthesis of triterpenoid triazine derivatives from allobetulone and betulonic acid with biological activities
  84. Synthetic Protocol toward Fused Pyrazolone Derivatives via a Michael Addition and Reductive Ring Closing Strategy
  85. 8-HaloBODIPYs and Their 8-(C, N, O, S) Substituted Analogues: Solvent Dependent UV–Vis Spectroscopy, Variable Temperature NMR, Crystal Structure Determination, and Quantum Chemical Calculations
  86. Formation of amides when other approaches have failed
  87. Tanshinone IIA Exhibits Anticonvulsant Activity in Zebrafish and Mouse Seizure Models
  88. Diterpene glycosides from Stevia phlebophylla A. Gray
  89. Alpha-Helical Destabilization of the Bcl-2-BH4-Domain Peptide Abolishes Its Ability to Inhibit the IP3 Receptor
  90. Synthesis and in vitro evaluation of a PDT active BODIPY–NLS conjugate
  91. Asymmetric Synthesis of 1-Aza-4-deoxypicropodophyllotoxin
  92. Scaffold Hopping via a Transannular Rearrangement–Encompassing Cascade
  93. Absolute configuration of 3-acetylbetulinic acid
  94. Preparation and characterization of hydrogels based on homopolymeric fractions of sodium alginate and PNIPAAm
  95. Total Synthesis of Septocylindrin B and C-Terminus Modified Analogues
  96. Fused derivatives of (iso)steviol via pericyclic reactions
  97. Stevioside and Steviol as Starting Materials in Organic Synthesis
  98. Tetranuclear d-f Metallostars: Synthesis, Relaxometric, and Luminescent Properties
  99. A Tripodal Ruthenium–Gadolinium Metallostar as a Potential αvβ3Integrin Specific Bimodal Imaging Contrast Agent
  100. Anticonvulsant activity of bisabolene sesquiterpenoids of Curcuma longa in zebrafish and mouse seizure models
  101. Selective LC-MS/MS method for the identification of BMAA from its isomers in biological samples
  102. Identification of a Small Molecule That Modulates Platelet Glycoprotein Ib-von Willebrand Factor Interaction
  103. An integrated fragment based screening approach for the discovery of small molecule modulators of the VWF–GPIbα interaction
  104. The C Terminus of Bax Inhibitor-1 Forms a Ca2+-permeable Channel Pore
  105. A Heterobimetallic Ruthenium–Gadolinium Complex as a Potential Agent for Bimodal Imaging
  106. Rational Design, Synthesis, and Spectroscopic and Photophysical Properties of a Visible-Light-Excitable, Ratiometric, Fluorescent Near-Neutral pH Indicator Based on BODIPY
  107. Isosteviol as a Starting Material in Organic Synthesis
  108. A Modular Approach towards the Synthesis of Target-Specific MRI Contrast Agents
  109. Synthesis of the orthogonally protected amino alcohol Phaol and analogs
  110. 2-(4-Methoxybenzyl)-4,6-diphenyl-2,5-diazabicyclo[2.2.2]oct-5-en-3-one
  111. Comparison of distance information in [TOAC1, Glu(OMe)7, 18, 19] alamethicin F50/5 from paramagnetic relaxation enhancement measurements with data obtained from an X-ray diffraction-based model
  112. Measuring cooperative Rev protein-protein interactions on Rev responsive RNA by fluorescence resonance energy transfer
  113. ChemInform Abstract: Synthesis of Pyridodiazepinediones by Using the Ugi Multicomponent Reaction.
  114. Triple Hyp→Pro replacement in integramide A, a peptaib inhibitor of HIV‐1 integrase: Effect on conformation and bioactivity
  115. Synthesis of Pyridodiazepinediones by Using the Ugi Multicomponent Reaction
  116. Generalized solvent scales as a tool for investigating solvent dependence of spectroscopic and kinetic parameters. Application to fluorescent BODIPY dyes
  117. Influence of Reducing Carbohydrates on (6S)-5-Methyltetrahydrofolic Acid Degradation during Thermal Treatments
  118. Direct functionalization of BODIPY dyes by oxidative nucleophilic hydrogen substitution at the 3- or 3,5-positions
  119. Synthesis and Substitution of 8-(4,6-Dichloropyrimidin-5-yl)-BODIPY
  120. Synthesis and Biological Evaluation of Bridged Analogues of the Platelet Aggregation Inhibitor Trifenagrel
  121. Flavonoids from Senecio viscosus
  122. Mechanism and Related Kinetics of 5-Methyltetrahydrofolic Acid Degradation during Combined High Hydrostatic Pressure−Thermal Treatments
  123. Photophysics and stability of cyano-substituted boradiazaindacene dyes
  124. Synthesis and modifications of a small library of 1,4-benzodiazepin-3-ones toward potential inhibitors of the collagen—von Willebrand Factor interaction
  125. Synthesis of 5,5′-Dialkyl-6,6′-dichloro-2, 2′-bipyridines
  126. ChemInform Abstract: Synthesis of Pyrazino[1,2‐a]benzimidazol‐1(2H)ones via a Microwave‐Assisted Buchwald—Hartwig Type Reaction.
  127. Structural property investigations of 1-[2-(2-methoxyphenyl)ethyl]piperidinium chloride: An experimental and computational study
  128. Synthesis of Highly Functionalized 2(1H)-Pyrazinone 3-Carboxamide Scaffolds
  129. Synthesis of pyrazino[1,2-a]benzimidazol-1(2H)ones via a microwave assisted Buchwald–Hartwig type reaction
  130. Ratiometric, Fluorescent BODIPY Dye with Aza Crown Ether Functionality: Synthesis, Solvatochromism, and Metal Ion Complex Formation
  131. Matrix-isolation FT-IR and theoretical investigation of the competitive intramolecular hydrogen bonding in 5-methyl-3-nitro-2-hydroxyacetophenone
  132. Spirocyclic Pyridoazepine Analogues of Galanthamine: Synthesis, Modelling Studies and Evaluation as Inhibitors of Acetylcholinesterase
  133. ATR-IR spectroscopic study of the structural changes in the hydrophobic region of ICPAN/DPPC bilayers
  134. Synthesis and Biological Evaluation of Methylene-Bridged Analogs of the Potent Cannabinoid Receptor Antagonist Rimonabant
  135. trans-Chlorido[6-chloro-4-(4-methoxybenzyl)-3-oxo-3,4-dihydropyrazin-2-yl]bis(triphenylphosphine)palladium(II)
  136. Matrix-isolation FT-IR and theoretical investigation of the vibrational properties of the sterically hindered ortho-hydroxy acylaromatic Schiff bases
  137. Synthesis of Spirocyclic Pyridoazepines as Analogues of Galanthamine by Nucleophilic Aromatic Substitution of 3‐Substituted 2‐Chloropyridines
  138. Synthesis of Methylene‐Bridged Analogues of Biologically Active Pteridine Derivatives.
  139. Synthesis of Methylene‐Bridged Analogues of Biologically Active Pteridine Derivatives
  140. Conformational Analysis of TOAC‐Labelled Alamethicin F50/5 Analogues
  141. Design, Synthesis and Evaluation of Serine Protease Inhibitor Analogues
  142. Synthesis of 2(1H)‐Pyrazinone Phosphonates via an Arbuzov‐Type Reaction.
  143. Diastereoselective Diels—Alder Additions of Ethene to Substituted Homochiral 2(1H)‐Pyrazinones.
  144. Diastereoselective Diels–Alder Additions of Ethene to Substituted Homochiral 2(1H)-Pyrazinones
  145. Photophysics of 3,5-diphenoxy substituted BODIPY dyes in solution
  146. Synthesis of 2(1H)-Pyrazinone Phosphonates via an Arbuzov-type Reaction
  147. 3,5‐Dihalo‐2(1H)‐pyrazinones: Versatile Scaffolds in Organic Synthesis
  148. 3,5-Dihalo-2(1 H )-pyrazinones: Versatile Scaffolds in Organic Synthesis
  149. Photophysical properties of an on/off fluorescent pH indicator excitable with visible light based on a borondipyrromethene-linked phenol
  150. Synthesis of 1,5-disubstituted 4-haloimidazoles from α-aminonitriles
  151. Solvent and pH Dependent Fluorescent Properties of a Dimethylaminostyryl Borondipyrromethene Dye in Solution
  152. Design, Synthesis, and Preferred Conformation of Peptides Based on a Highly Constrained, β,β′-Diphenyl Substituted Cyclopropane α-Amino Acid
  153. Preferred 3D-Structure of Peptides Rich in a Severely Conformationally Restricted Cyclopropane Analogue of Phenylalanine
  154. Structure based design of simplified analogues of insect kinins
  155. Development of New Amino(oxo)piperidinecarboxylate Scaffolds and Their Evaluation as -Turn Mimics
  156. BODIPY-Based Hydroxyaryl Derivatives as Fluorescent pH Probes
  157. Expanding the substitution pattern of 2(1H)-pyrazinones via Suzuki and Heck reactions
  158. Synthesis of sidechain adapted β-turn mimics for modifying the C-terminus of substance P
  159. Turn and Helical Peptide Handedness Governed Exclusively by Side-Chain Chiral Centers
  160. Synthesis of Novel Functionalised Symmetric Bi-2(1 H )-pyrazinones
  161. Design and synthesis of novel type VI-like β-turn mimetics. Diversity at the i+1 and the i+2 position
  162. New Routes for the Synthesis of 3‐ and 5‐Substituted 2(1H)‐Pyrazinones.
  163. Acid catalysed methanolysis of 2,5-diazabicyclo[2.2.2]octane-3,6-diones: scope and limitations
  164. New routes for the synthesis of 3- and 5-substituted 2(1H)-pyrazinones
  165. Stereoselective transformation of pyrazinones into substituted analogues of cis-5-amino-6-oxo-2-piperidinemethanol and cis-5-amino-2-piperidinemethanol
  166. Development of a Functionalizable External β-Turn Mimic Based on a cis-Fused 1,7-Naphthyridine Scaffold
  167. High-Speed Microwave-Promoted Hetero-Diels−Alder Reactions of 2(1H)-Pyrazinones in Ionic Liquid Doped Solvents
  168. Stereoselective intramolecular Diels–Alder reactions of 3-alkenyl(oxy)-2(1H)-pyrazinones
  169. Intramolecular Diels–Alder reactions of N-alkenyl-2(1H)-pyrazinones: generation of a novel type of cis-1,7-naphthyridine
  170. Synthesis of a conformationally restricted dipeptide analogue and its evaluation as a β-turn mimic
  171. Divergent pathways in the intramolecular diels-alder reaction of 2(1H)-pyrazinones substituted at the 3-position with a phenylalkyne containing side chain