All Stories

  1. Mucoadhesive nanogels by ionotropic crosslinking of chitosan-g-oligo(NiPAam) polymeric micelles as novel drug nanocarriers

    Article • Nanomedicine, February 2016, Future Medicine

    Professor Alejandro SOSNIK

  2. Didanosine-loaded poly(epsilon-caprolactone) microparticles by a coaxial electrohydrodynamic atomization (CEHDA) technique

    Article • Journal of Materials Chemistry B, January 2015, Royal Society of Chemistry

    Professor Alejandro SOSNIK

  3. Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs

    Article • Biomaterials, January 2015, Elsevier

    Professor Alejandro SOSNIK

  4. Chitosan-g-oligo(epsilon-caprolactone) polymeric micelles: microwave-assisted synthesis and physicochemical and cytocompatibility characterization

    Article • Journal of Materials Chemistry B, January 2015, Royal Society of Chemistry

    Professor Alejandro SOSNIK

  5. Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review

    Article • Progress in Polymer Science, December 2014, Elsevier

    Professor Alejandro SOSNIK

  6. Spray-dried didanosine-loaded polymeric particles for enhanced oral bioavailability

    Article • Colloids and Surfaces B Biointerfaces, November 2014, Elsevier

    Professor Alejandro SOSNIK

  7. Production of Drug-Loaded Polymeric Nanoparticles by Electrospraying Technology

    Article • Journal of Biomedical Nanotechnology, September 2014, American Scientific Publishers

    Professor Alejandro SOSNIK

  8. Novel Poly(Ethylene Oxide)-b-Poly(Propylene Oxide) Copolymer-Glucose Conjugate by the Microwave-Assisted Ring Opening of a Sugar Lactone

    Article • Macromolecular Bioscience, August 2014, Wiley

    Professor Alejandro SOSNIK

  9. Rifampicin-loaded ‘flower-like’ polymeric micelles for enhanced oral bioavailability in an extemporaneous liquid fixed-dose combination with isoniazid

    Article • Nanomedicine, August 2014, Future Medicine

    Professor Alejandro SOSNIK

  10. Enhanced oral bioavailability of the antiretroviral efavirenz encapsulated in poly(epsilon-caprolactone) nanoparticles by a spray-drying method

    Article • Nanomedicine, August 2014, Future Medicine

    Professor Alejandro SOSNIK

  11. Encapsulation of the Antimicrobial and Immunomodulator Agent Nitazoxanide Within Polymeric Micelles

    Article • Journal of Nanoscience and Nanotechnology, June 2014, American Scientific Publishers

    Professor Alejandro SOSNIK

  12. Nanomedicines in the future of pediatric therapy

    Article • Advanced Drug Delivery Reviews, June 2014, Elsevier

    Professor Alejandro SOSNIK

  13. NANOASSEMBLIES: COVALENT DERIVATIVES OF NEVIRAPINE WITH POLYETHYNE GLYCOL DIACRYLATE

    Article • December 2013, Editora Edgard Blucher, Ltda.

    Professor Alejandro SOSNIK

  14. Reversal of multidrug resistance by the inhibition of ATP-binding cassette pumps employing “Generally Recognized As Safe” (GRAS) nanopharmaceuticals: A review

    Article • Advanced Drug Delivery Reviews, November 2013, Elsevier

    Professor Alejandro SOSNIK

  15. Production of pure indinavir free base nanoparticles by a supercritical anti-solvent (SAS) method

    Article • Drug Development and Industrial Pharmacy, September 2013, Taylor & Francis

    Professor Alejandro SOSNIK

  16. Hydrolyzed Galactomannan-Modified Nanoparticles and Flower-Like Polymeric Micelles for the Active Targeting of Rifampicin to Macrophages

    Article • Journal of Biomedical Nanotechnology, June 2013, American Scientific Publishers

    Professor Alejandro SOSNIK

  17. Temperature- and pH-sensitive Polymeric Micelles for Drug Encapsulation, Release and Targeting

    Article • April 2013, Royal Society of Chemistry

    Professor Alejandro SOSNIK

  18. β-Cyclodextrin hydrogels for the ocular release of antibacterial thiosemicarbazones

    Article • Carbohydrate Polymers, April 2013, Elsevier

    Professor Alejandro SOSNIK, Dr Carmen Alvarez-Lorenzo, Professor Gabriel O. Gutkind

  19. Nanoparticle-in-Microparticle Delivery Systems (NiMDS): Production, Administration Routes and Clinical Potential

    Article • Journal of Biomaterials and Tissue Engineering, February 2013, American Scientific Publishers

    Professor Alejandro SOSNIK

  20. A Special Issue on Nanomedicine in Latin America

    Article • Journal of Biomaterials and Tissue Engineering, February 2013, American Scientific Publishers

    Professor Alejandro SOSNIK

  21. Intranasal administration of antiretroviral-loaded micelles for anatomical targeting to the brain in HIV

    Article • Nanomedicine, February 2013, Future Medicine

    Professor Alejandro SOSNIK

  22. Poly(ɛ-caprolactone), Eudragit® RS 100 and poly(ɛ-caprolactone)/Eudragit® RS 100 blend submicron particles for the sustained release of the antiretroviral efavirenz

    Article • Colloids and Surfaces B Biointerfaces, February 2013, Elsevier

    Professor Alejandro SOSNIK

  23. Nanobiotechnology

    Article • BioMed Research International, January 2013, Hindawi Publishing Corporation

    Professor Alejandro SOSNIK

  24. Lactosylated poly(ethylene oxide)–poly(propylene oxide) block copolymers for potential active targeting: synthesis and physicochemical and self-aggregation characterization

    Article • Journal of Nanoparticle Research, January 2013, Springer Science + Business Media

    Professor Alejandro SOSNIK

  25. Micro/Nanostructured Hyaluronic Acid Matrices with Tuned Swelling and Drug Release Properties

    Article • Biomacromolecules, December 2012, American Chemical Society (ACS)

    Professor Alejandro SOSNIK

  26. Downregulation of mdr1 and abcg2 genes is a mechanism of inhibition of efflux pumps mediated by polymeric amphiphiles

    Article • Bioorganic & Medicinal Chemistry Letters, November 2012, Elsevier

    Professor Alejandro SOSNIK

  27. Antiviral activity against the hepatitis C virus (HCV) of 1-indanone thiosemicarbazones and their inclusion complexes with hydroxypropyl-β-cyclodextrin

    Article • European Journal of Pharmaceutical Sciences, October 2012, Elsevier

    Professor Alejandro SOSNIK

  28. Photodynamic Effects of Zinc(II) Phthalocyanine‐Loaded Polymeric Micelles in Human Nasopharynx KB Carcinoma Cells

    Article • Photochemistry and Photobiology, September 2012, Wiley

    Professor Alejandro SOSNIK

  29. Single and mixed poloxamine micelles as nanocarriers for solubilization and sustained release of ethoxzolamide for topical glaucoma therapy

    Article • Journal of The Royal Society Interface, April 2012, Royal Society Publishing

    Professor Alejandro SOSNIK

  30. Novel formulation and drug delivery strategies for the treatment of pediatric poverty-related diseases

    Article • Expert Opinion on Drug Delivery, January 2012, Informa Healthcare

    Professor Alejandro SOSNIK

  31. Chitosan and Chitosan Derivatives for Biological Applications: Chemistry and Functionalization

    Article • International Journal of Carbohydrate Chemistry, December 2011, Hindawi Publishing Corporation

    Professor Alejandro SOSNIK

  32. Efavirenz is a substrate and in turn modulates the expression of the efflux transporter ABCG2/BCRP in the gastrointestinal tract of the rat

    Article • Biochemical Pharmacology, November 2011, Elsevier

    Professor Alejandro SOSNIK

  33. Novel 1-indanone Thiosemicarbazone Antiviral Candidates: Aqueous Solubilization and Physical Stabilization by Means of Cyclodextrins

    Article • Pharmaceutical Research, October 2011, Springer Science + Business Media

    Professor Alejandro SOSNIK

  34. Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery

    Article • International Journal of Carbohydrate Chemistry, October 2011, Hindawi Publishing Corporation

    Dr José das Neves, Professor Alejandro SOSNIK

  35. Synergistic encapsulation of the anti-HIV agent efavirenz within mixed poloxamine/poloxamer polymeric micelles

    Article • Nanomedicine Nanotechnology Biology and Medicine, October 2011, Elsevier

    Professor Alejandro SOSNIK

  36. Cryoprotection-lyophilization and physical stabilization of rifampicin-loaded flower-like polymeric micelles

    Article • Journal of The Royal Society Interface, August 2011, Royal Society Publishing

    Professor Alejandro SOSNIK

  37. Microwave-assisted polymer synthesis (MAPS) as a tool in biomaterials science: How new and how powerful

    Article • Progress in Polymer Science, August 2011, Elsevier

    Professor Alejandro SOSNIK

  38. PEO-PPO Block Copolymers for Passive Micellar Targeting and Overcoming Multidrug Resistance in Cancer Therapy

    Article • Current Drug Targets, July 2011, Bentham Science Publishers

    Professor Alejandro SOSNIK

  39. Poloxamines Display a Multiple Inhibitory Activity of ATP-Binding Cassette (ABC) Transporters in Cancer Cell Lines

    Article • Molecular Pharmaceutics, June 2011, American Chemical Society (ACS)

    Professor Alejandro SOSNIK

  40. ChemInform Abstract: Hydrogels with Cyclodextrins as Highly Versatile Drug Delivery Systems

    Article • ChemInform, May 2011, Wiley

    Professor Alejandro SOSNIK, Dr Carmen Alvarez-Lorenzo

  41. Fast and efficient synthesis of high molecular weight poly(epsilon‐caprolactone) diols by microwave‐assisted polymer synthesis

    Article • Journal of Applied Polymer Science, March 2011, Wiley

    Professor Alejandro SOSNIK

  42. Oral pharmacokinetics of the anti-HIV efavirenz encapsulated within polymeric micelles

    Article • Biomaterials, March 2011, Elsevier

    Professor Alejandro SOSNIK

  43. Inhibition of P-glycoprotein pumps by PEO–PPO amphiphiles: branched versus linear derivatives

    Article • Nanomedicine, November 2010, Future Medicine

    Professor Alejandro SOSNIK, Dr Carmen Alvarez-Lorenzo

  44. N-alkylation of poloxamines modulates micellar assembly and encapsulation and release of the antiretroviral efavirenz

    Article • European Journal of Pharmaceutics and Biopharmaceutics, September 2010, Elsevier

    Professor Alejandro SOSNIK, Dr Carmen Alvarez-Lorenzo

  45. Molecular implications in the nanoencapsulation of the anti-tuberculosis drug rifampicin within flower-like polymeric micelles

    Article • Colloids and Surfaces B Biointerfaces, September 2010, Elsevier

    Professor Alejandro SOSNIK

  46. Nanotechnology contributions to the pharmacotherapy of pediatric HIV: a dual scientific and ethical challenge and a still pending agenda

    Article • Nanomedicine, August 2010, Future Medicine

    Professor Alejandro SOSNIK

  47. Development and Preclinical Evaluation of Acellular Collagen Scaffolding and Autologous Artificial Connective Tissue in the Regeneration of Oral Mucosa Wounds

    Article • Tissue Engineering Part A, May 2010, Mary Ann Liebert Inc

    Professor Alejandro SOSNIK

  48. A Highly Concentrated and Taste-Improved Aqueous Formulation of Efavirenz for a More Appropriate Pediatric Management of the Anti-HIV Therapy

    Article • Current HIV Research, April 2010, Bentham Science Publishers

    Professor Alejandro SOSNIK

  49. Episcleral Implants for Topotecan Delivery to the Posterior Segment of the Eye

    Article • Investigative Opthalmology & Visual Science, April 2010, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Alejandro SOSNIK

  50. Drug Delivery Systems and Liver Targeting for the Improved Pharmacotherapy of the Hepatitis B Virus (HBV) Infection

    Article • Pharmaceutical Research, March 2010, Springer Science + Business Media

    Professor Alejandro SOSNIK

  51. Nanotechnology solutions for infectious diseases in developing nations

    Article • Advanced Drug Delivery Reviews, March 2010, Elsevier

    Professor Alejandro SOSNIK

  52. New old challenges in tuberculosis: Potentially effective nanotechnologies in drug delivery

    Article • Advanced Drug Delivery Reviews, March 2010, Elsevier

    Professor Alejandro SOSNIK

  53. Repair of Bone Defect Using Bone Marrow Cells and Demineralized Bone Matrix Supplemented with Polymeric Materials

    Article • Current Stem Cell Research & Therapy, March 2010, Bentham Science Publishers

    Professor Alejandro SOSNIK

  54. Novel long-term anticonvulsant treatment with gabapentin without causing memory impairment in mice

    Article • Epilepsy & Behavior, February 2010, Elsevier

    Professor Alejandro SOSNIK

  55. Self-aggregation behaviour of novel thiosemicarbazone drug candidates with potential antiviral activity

    Article • New Journal of Chemistry, January 2010, Royal Society of Chemistry

    Professor Alejandro SOSNIK

  56. Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability

    Article • Nanomedicine, January 2010, Future Medicine

    Professor Alejandro SOSNIK

  57. Solution Thermodynamics of Triclocarban in Organic Solvents of Different Hydrogen Bonding Capability

    Article • Journal of Solution Chemistry, November 2009, Springer Science + Business Media

    Professor Alejandro SOSNIK

  58. Drug delivery systems in HIV pharmacotherapy: What has been done and the challenges standing ahead

    Article • Journal of Controlled Release, August 2009, Elsevier

    Professor Alejandro SOSNIK

  59. Indinavir-Loaded pH-Sensitive Microparticles for Taste Masking: Toward Extemporaneous Pediatric Anti-HIV/AIDS Liquid Formulations with Improved Patient Compliance

    Article • AAPS PharmSciTech, January 2009, American Association of Pharmaceutical Scientists (AAPS)

    Professor Alejandro SOSNIK

  60. Poloxamine Hydrogels: from low Cell Adhesion Substrates to Matrices with Improved Cytocompatibility for Tissue Engineering Applications

    Article • January 2009, Springer Science + Business Media

    Professor Alejandro SOSNIK

  61. Solubility of the Antimicrobial Agent Triclosan in Organic Solvents of Different Hydrogen Bonding Capabilities at Several Temperatures

    Article • Journal of Chemical & Engineering Data, October 2008, American Chemical Society (ACS)

    Professor Alejandro SOSNIK

  62. In vitro/in vivo characterization of melt-molded gabapentin-loaded poly(epsilon-caprolactone) implants for sustained release in animal studies

    Article • European Journal of Pharmaceutics and Biopharmaceutics, October 2008, Elsevier

    Professor Alejandro SOSNIK

  63. Self-Associative Behavior and Drug-Solubilizing Ability of Poloxamine (Tetronic) Block Copolymers

    Article • Langmuir, September 2008, American Chemical Society (ACS)

    Professor Alejandro SOSNIK, Dr Carmen Alvarez-Lorenzo

  64. Triclosan-loaded poloxamine micelles for enhanced topical antibacterial activity against biofilm

    Article • European Journal of Pharmaceutics and Biopharmaceutics, June 2008, Elsevier

    Professor Alejandro SOSNIK

  65. Polymeric Nanocarriers: New Endeavors for the Optimization of the Technological Aspects of Drugs

    Article • Recent Patents on Biomedical Engineering, January 2008, Bentham Science Publishers

    Professor Alejandro SOSNIK

  66. Entalpía de disolución de sulfacetamida sódica en agua: comparación entre la calorimetría isoperibólica de solución y el método de van't Hoff

    Article • Química Nova, January 2008, FapUNIFESP (SciELO)

    Professor Alejandro SOSNIK

  67. Lactoyl‐poloxamine/collagen matrix for cell‐containing tissue engineering modules

    Article • Journal of Biomedical Materials Research Part A, October 2007, Wiley

    Professor Alejandro SOSNIK

  68. Chain extension as a strategy for the development of improved reverse thermo‐responsive polymers

    Article • Polymers for Advanced Technologies, June 2007, Wiley

    Professor Alejandro SOSNIK

  69. Poly(ethylene oxide)–poly(propylene oxide) block copolymer micelles as drug delivery agents: Improved hydrosolubility, stability and bioavailability of drugs

    Article • European Journal of Pharmaceutics and Biopharmaceutics, June 2007, Elsevier

    Professor Alejandro SOSNIK

  70. Surface study of collagen/poloxamine hydrogels by a ‘deep freezing’ ToF-SIMS approach

    Article • Biomaterials, April 2006, Elsevier

    Professor Alejandro SOSNIK

  71. PEO–PPO–PEO-based poly(ether ester urethane)s as degradable reverse thermo-responsive multiblock copolymers

    Article • Biomaterials, March 2006, Elsevier

    Professor Alejandro SOSNIK

  72. Semi-synthetic collagen/poloxamine matrices for tissue engineering

    Article • Biomaterials, December 2005, Elsevier

    Professor Alejandro SOSNIK

  73. Methylation of Poloxamine for Enhanced Cell Adhesion

    Article • Biomacromolecules, November 2005, American Chemical Society (ACS)

    Professor Alejandro SOSNIK

  74. Collagen/Poloxamine Hydrogels: Cytocompatibility of Embedded HepG2 Cells and Surface-Attached Endothelial Cells

    Article • Tissue Engineering, November 2005, Mary Ann Liebert Inc

    Professor Alejandro SOSNIK, Dr Alison p McGuigan

  75. Smart Hydrogels for in Situ Generated Implants

    Article • Biomacromolecules, March 2005, American Chemical Society (ACS)

    Professor Alejandro SOSNIK

  76. Reverse thermo-responsive poly(ethylene oxide) and poly(propylene oxide) multiblock copolymers

    Article • Biomaterials, February 2005, Elsevier

    Professor Alejandro SOSNIK

  77. Ethoxysilane-capped PEO–PPO–PEO triblocks: a new family of reverse thermo-responsive polymers

    Article • Biomaterials, June 2004, Elsevier

    Professor Alejandro SOSNIK

  78. Poly(ethylene glycol)-poly(epsilon-caprolactone) block oligomers as injectable materials

    Article • Polymer, November 2003, Elsevier

    Professor Alejandro SOSNIK

  79. Improved reverse thermo-responsive polymeric systems

    Article • Biomaterials, September 2003, Elsevier

    Professor Alejandro SOSNIK

  80. Crosslinkable PEO-PPO-PEO-based reverse thermo-responsive gels as potentially injectable materials

    Article • Journal of Biomaterials Science Polymer Edition, January 2003, Taylor & Francis

    Professor Alejandro SOSNIK

  81. ChemInform Abstract: Synthesis and Study of Reactivity in the Diels‐Alder Reaction of 3‐ Methoxycarbonylindeno(1,2‐b)pyran‐2(5H)‐ones.

    Article • ChemInform, March 1997, Wiley

    Professor Alejandro SOSNIK