All Stories

  1. Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers

    Article • Vaccine, September 2014, Elsevier

    Dr veronica diermayr

  2. VS-5584, a Novel and Highly Selective PI3K/mTOR Kinase Inhibitor for the Treatment of Cancer

    Article • Molecular Cancer Therapeutics, December 2012, American Association for Cancer Research (AACR)

    Dr veronica diermayr

  3. The oral HDAC inhibitor pracinostat (SB939) is efficacious and synergistic with the JAK2 inhibitor pacritinib (SB1518) in preclinical models of AML

    Article • Blood Cancer Journal, May 2012, Springer Science + Business Media

    Dr veronica diermayr

  4. Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia

    Article • Blood Cancer Journal, November 2011, Springer Science + Business Media

    Dr veronica diermayr

  5. TG02, a novel oral multi-kinase inhibitor of CDKs, JAK2 and FLT3 with potent anti-leukemic properties

    Article • Leukemia, August 2011, Springer Science + Business Media

    Dr veronica diermayr

  6. SB1518, a novel macrocyclic pyrimidine-based JAK2 inhibitor for the treatment of myeloid and lymphoid malignancies

    Article • Leukemia, June 2011, Springer Science + Business Media

    Dr veronica diermayr

  7. Pharmacodynamic Evaluation of the Target Efficacy of SB939, an Oral HDAC Inhibitor with Selectivity for Tumor Tissue

    Article • Molecular Cancer Therapeutics, May 2011, American Association for Cancer Research (AACR)

    Dr veronica diermayr

  8. Abstract 3570: SB1518, a novel JAK2/FLT3 inhibitor for the treatment of myeloid malignancies

    Article • Cancer Research, April 2011, American Association for Cancer Research (AACR)

    Dr veronica diermayr

  9. Phase I and pharmacodynamic study of an orally administered novel inhibitor of histone deacetylases, SB939, in patients with refractory solid malignancies

    Article • Annals of Oncology, March 2011, Oxford University Press (OUP)

    Dr veronica diermayr

  10. 78 TG02, a multi-kinase inhibitor with potent single agent and chemosensitization activity against solid tumors

    Article • European Journal of Cancer Supplements, November 2010, Elsevier

    Dr veronica diermayr

  11. Abstract 5436: The histone deacetylase inhibitor SB939 acts synergistically with Sorafenib in an orthotopic model of hepatucellular carcinoma

    Article • Cancer Research, April 2010, American Association for Cancer Research (AACR)

    Dr veronica diermayr

  12. Abstract 2542: TG02, a novel multi-kinase inhibitor with potent anti-leukemic activity

    Article • Cancer Research, April 2010, American Association for Cancer Research (AACR)

    Dr veronica diermayr

  13. SB939, a Novel Potent and Orally Active Histone Deacetylase Inhibitor with High Tumor Exposure and Efficacy in Mouse Models of Colorectal Cancer

    Article • Molecular Cancer Therapeutics, March 2010, American Association for Cancer Research (AACR)

    Dr veronica diermayr

  14. Abstract A185: Phase I clinical, pharmacokinetic, and pharmacodynamic study of SB939, an oral histone deacetylase inhibitor (HDACi), in patients with advanced solid tumors

    Article • Molecular Cancer Therapeutics, December 2009, American Association for Cancer Research (AACR)

    Dr veronica diermayr

  15. PP72 Demonstration of dose-dependent target inhibition using a quantitative biomarker assay for SB939, a potent, orally active HDAC inhibitor, in a Phase I clinical study in solid tumors

    Article • European Journal of Cancer Supplements, October 2009, Elsevier

    Dr veronica diermayr

  16. 83 POSTER A robust and quantitative biomarker assay for SB939, a potent, orally-active HDAC inhibitor

    Article • European Journal of Cancer Supplements, October 2008, Elsevier

    Dr veronica diermayr

  17. Modulation of the Interleukin-6 Receptor Subunit Glycoprotein 130 Complex and Its Signaling by LMO4 Interaction

    Article • Journal of Biological Chemistry, January 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr veronica diermayr

  18. A Novel Sequence in the Coiled-coil Domain of Stat3 Essential for Its Nuclear Translocation

    Article • Journal of Biological Chemistry, May 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr veronica diermayr

  19. Protein Kinase C delta Associates with the Interleukin-6 Receptor Subunit Glycoprotein (gp) 130 via Stat3 and Enhances Stat3-gp130 Interaction

    Article • Journal of Biological Chemistry, October 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr veronica diermayr

  20. Novel Mode of Interference with Nuclear Factor of Activated T-cells Regulation in T-cells by the Bacterial Metaboliten-Butyrate

    Article • Journal of Biological Chemistry, April 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr veronica diermayr

  21. Glycosphingolipid-Induced Relocation of Lyn and Syk into Detergent-Resistant Membranes Results in Mast Cell Activation

    Article • The Journal of Immunology, May 2000, The American Association of Immunologists

    Dr veronica diermayr

  22. The Balance between Sphingosine and Sphingosine-1-Phosphate Is Decisive for Mast Cell Activation after Fc∈ Receptor I Triggering

    Article • The Journal of Experimental Medicine, July 1999, Rockefeller University Press

    Dr veronica diermayr

  23. TNF–· and IL–5 Gene Induction in IgE plus Antigen–Stimulated Mast Cells Require Common and Distinct Signaling Pathways

    Article • International Archives of Allergy and Immunology, January 1999, Karger Publishers

    Dr veronica diermayr

  24. Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 component at the TNF  promoter in stimulated mast cells

    Article • Nucleic Acids Research, December 1998, Oxford University Press (OUP)

    Dr veronica diermayr

  25. A novel splice variant of the transcription factor Nrf1 interacts with the TNF  promoter and stimulates transcription

    Article • Nucleic Acids Research, May 1998, Oxford University Press (OUP)

    Dr veronica diermayr

  26. The ultrastructure of the cuticle of Nematoda. II. The cephalic cuticle of Stilbonematinae (Adenophorea, Desmodoridae)

    Article • Zoomorphology, July 1996, Springer Science + Business Media

    Dr veronica diermayr