All Stories

  1. The 6-Aminoquinolone WC5 Inhibits Different Functions of the Immediate-Early 2 (IE2) Protein of Human Cytomegalovirus That Are Essential for Viral Replication

    Article • Antimicrobial Agents and Chemotherapy, August 2014, ASM Journals

    Riccardo manganelli, Professor Arianna Loregian, Professor Giorgio Gribaudo

  2. Ethyl 1,8-Naphthyridone-3-carboxylates Downregulate Human Papillomavirus-16 E6 and E7 Oncogene Expression

    Article • Journal of Medicinal Chemistry, June 2014, American Chemical Society (ACS)

    Professor Arianna Loregian

  3. Optimization of Small-Molecule Inhibitors of Influenza Virus Polymerase: From Thiophene-3-Carboxamide to Polyamido Scaffolds

    Article • Journal of Medicinal Chemistry, May 2014, American Chemical Society (ACS)

    Professor Arianna Loregian, Former Full Professor Renzo Ruzziconi

  4. Antiviral strategies against influenza virus: towards new therapeutic approaches

    Article • Cellular and Molecular Life Sciences, April 2014, Springer Science + Business Media

    Professor Arianna Loregian

  5. Approaches for the Generation of New Anti-cytomegalovirus Agents: Identification of Protein–Protein Interaction Inhibitors and Compounds Against the HCMV IE2 Protein

    Article • January 2014, Springer Science + Business Media

    Professor Arianna Loregian, Professor Giorgio Gribaudo

  6. Structural Investigation of Cycloheptathiophene-3-carboxamide Derivatives Targeting Influenza Virus Polymerase Assembly

    Article • Journal of Medicinal Chemistry, December 2013, American Chemical Society (ACS)

    Professor Arianna Loregian

  7. Regulated Transport into the Nucleus of Herpesviridae DNA Replication Core Proteins

    Article • Viruses, September 2013, MDPI AG

    Gualtiero Alvisi, Professor Arianna Loregian

  8. Inhibition of herpesvirus and influenza virus replication by blocking polymerase subunit interactions

    Article • Antiviral Research, September 2013, Elsevier

    Professor Arianna Loregian

  9. Design, Synthesis, and Evaluation of WC5 Analogues as Inhibitors of Human Cytomegalovirus Immediate‐Early 2 Protein, a Promising Target for Anti‐HCMV Treatment

    Article • ChemMedChem, June 2013, Wiley

    Professor Arianna Loregian

  10. How academic labs can approach the drug discovery process as a way to synergize with big pharma

    Article • Trends in Microbiology, June 2013, Elsevier

    Professor Arianna Loregian

  11. The Human Cytomegalovirus DNA Polymerase Processivity Factor UL44 Is Modified by SUMO in a DNA-Dependent Manner

    Article • PLoS ONE, November 2012, PLOS

    Professor Arianna Loregian

  12. Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses

    Article • Antimicrobial Agents and Chemotherapy, August 2012, ASM Journals

    Professor Arianna Loregian

  13. Effects of hepatitis C virus infection on the pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected patients

    Article • Journal of Infection and Chemotherapy, January 2012, Elsevier

    Dr Antonio Di Biagio, Professor Arianna Loregian

  14. Early inhibitors of human cytomegalovirus: State-of-art and therapeutic perspectives

    Article • Pharmacology & Therapeutics, September 2011, Elsevier

    Professor Arianna Loregian

  15. Multiple phosphorylation sites at the C-terminus regulate nuclear import of HCMV DNA polymerase processivity factor ppUL44

    Article • Virology, September 2011, Elsevier

    Professor Arianna Loregian

  16. Strategies and Methods in Monitoring and Targeting Protein–Protein Interactions

    Article • March 2010, Wiley

    Professor Arianna Loregian

  17. Human cytomegalovirus DNA replication: antiviral targets and drugs

    Article • Reviews in Medical Virology, November 2007, Wiley

    Professor Arianna Loregian

  18. A Point Mutation in a Herpesvirus Polymerase Determines Neuropathogenicity

    Article • PLoS Pathogens, November 2007, PLOS

    Professor Arianna Loregian, Laura Goodman

  19. Measurement of ribavirin and evaluation of its stability in human plasma by high-performance liquid chromatography with UV detection

    Article • Journal of Chromatography B, September 2007, Elsevier

    Professor Arianna Loregian

  20. Simple determination of the HIV protease inhibitor atazanavir in human plasma by high-performance liquid chromatography with UV detection

    Article • Journal of Pharmaceutical and Biomedical Analysis, October 2006, Elsevier

    Professor Arianna Loregian

  21. Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses

    Article • Antiviral Research, October 2006, Elsevier

    Professor Arianna Loregian

  22. Cloning, Expression, and Functional Characterization of the Equine Herpesvirus 1 DNA Polymerase and Its Accessory Subunit

    Article • Journal of Virology, July 2006, ASM Journals

    Professor Arianna Loregian

  23. Selective Anti-Cytomegalovirus Compounds Discovered by Screening for Inhibitors of Subunit Interactions of the Viral Polymerase

    Article • Chemistry & Biology, February 2006, Elsevier

    Professor Arianna Loregian

  24. Disruption of the interactions between the subunits of herpesvirus DNA polymerases as a novel antiviral strategy

    Article • Clinical Microbiology and Infection, June 2005, Elsevier

    Professor Arianna Loregian

  25. Disruption of protein–protein interactions: Towards new targets for chemotherapy

    Article • Journal of Cellular Physiology, May 2005, Wiley

    Professor Arianna Loregian

  26. Strategies and Methods in Monitoring and Targeting Protein–Protein Interactions

    Article • January 2005, Wiley

    Professor Arianna Loregian

  27. The Cytomegalovirus DNA Polymerase Subunit UL44 Forms a C Clamp-Shaped Dimer

    Article • Molecular Cell, July 2004, Elsevier

    Professor Arianna Loregian

  28. pH-Dependent Conformational Changes and Topology of a Herpesvirus Translocating Peptide in a Membrane-Mimetic Environment

    Article • Biochemistry, July 2004, American Chemical Society (ACS)

    Professor Arianna Loregian

  29. Inhibition of Human Cytomegalovirus DNA Polymerase by C-Terminal Peptides from the UL54 Subunit

    Article • Journal of Virology, August 2003, ASM Journals

    Professor Arianna Loregian

  30. The Sp1 transcription factor does not directly interact with the HIV‐1 Tat protein

    Article • Journal of Cellular Physiology, June 2003, Wiley

    Professor Arianna Loregian

  31. Interaction of Sp1 transcription factor with HIV‐1 Tat protein: looking for cellular partners

    Article • FEBS Letters, April 2003, Wiley

    Professor Arianna Loregian

  32. Protein–protein interactions as targets for antiviral chemotherapy

    Article • Reviews in Medical Virology, July 2002, Wiley

    Professor Arianna Loregian

  33. Separation methods for acyclovir and related antiviral compounds

    Article • Journal of Chromatography B Biomedical Sciences and Applications, November 2001, Elsevier

    Professor Arianna Loregian

  34. Analysis of the antigen specific T cell repertoires in HIV infection

    Article • Immunology Letters, November 2001, Elsevier

    Professor Arianna Loregian, Dr Emanuele Pontali, Roberto Accolla

  35. The Catalytic Subunit of Herpes Simplex Virus Type 1 DNA Polymerase Contains a Nuclear Localization Signal in the UL42-Binding Region

    Article • Virology, July 2000, Elsevier

    Professor Arianna Loregian

  36. Use ofVibriospp. for Expression ofEscherichia coliEnterotoxin B Subunit Fusion Proteins: Purification and Characterization of a Chimera Containing a C-Terminal Fragment of DNA Polymerase from Herpes Simplex Virus Type 1

    Article • Protein Expression and Purification, November 1996, Elsevier

    Professor Arianna Loregian

  37. Identification and characterization of an extracellular protease activity produced by the marine Vibriosp 60

    Article • FEMS Microbiology Letters, February 1996, Oxford University Press (OUP)

    Alessandro Marcello, Professor Arianna Loregian

  38. Peptide disruption of protein-protein complexes: a novel strategy for antiviral therapy

    Article • Antiviral Research, March 1995, Elsevier

    Alessandro Marcello, Professor Arianna Loregian

  39. Quantitative Analysis of Ribonucleotide Triphosphates in Cell Extracts by High-Performance Liquid Chromatography and Micellar Electrokinetic Capillary Chromatography: A Comparative Study

    Article • Analytical Chemistry, September 1994, American Chemical Society (ACS)

    Professor Arianna Loregian

  40. Efficient extracellular production of hybridE. coliheat-labile enterotoxin B subunits in a marine vibrio

    Article • FEMS Microbiology Letters, March 1994, Oxford University Press (OUP)

    Alessandro Marcello, Professor Arianna Loregian

  41. Effect of neutral and acidic phospholipids on mitochondrial ATP synthase secondary structure

    Article • FEBS Letters, December 1993, Wiley

    Professor Arianna Loregian