All Stories

  1. Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt

    Article • Proceedings of the National Academy of Sciences, February 2021, Proceedings of the National Academy of Sciences

    Professor Luc Brunsveld

  2. Carborane–β-cyclodextrin complexes as a supramolecular connector for bioactive surfaces

    Article • Journal of Materials Chemistry B, January 2015, Royal Society of Chemistry

    Professor Luc Brunsveld

  3. Determination of dabigatran, rivaroxaban and apixaban by ultra‐performance liquid chromatography – tandem mass spectrometry (UPLC‐MS/MS) and coagulation assays for therapy monitoring of novel direct oral anticoagulants

    Article • Journal of Thrombosis and Haemostasis, October 2014, Elsevier

    Professor Luc Brunsveld

  4. Evaluation of Fluorophores to Label SNAP-Tag Fused Proteins for Multicolor Single-Molecule Tracking Microscopy in Live Cells

    Article • Biophysical Journal, August 2014, Elsevier

    Professor Luc Brunsveld

  5. A Natural‐Product Switch for a Dynamic Protein Interface

    Article • Angewandte Chemie, May 2014, Wiley

    Professor Luc Brunsveld

  6. A Natural‐Product Switch for a Dynamic Protein Interface

    Article • Angewandte Chemie International Edition, May 2014, Wiley

    Professor Luc Brunsveld

  7. Modulators of Protein–Protein Interactions

    Article • Chemical Reviews, April 2014, American Chemical Society (ACS)

    Professor Luc Brunsveld

  8. Supramolecular Systems in Biomedical Fields. Edited by Hans‐Jörg Schneider.

    Article • ChemBioChem, April 2014, Wiley

    Professor Luc Brunsveld

  9. Site‐Specific Protection and Dual Labeling of Human Epidermal Growth Factor (hEGF) for Targeting, Imaging, and Cargo Delivery

    Article • Chemistry - A European Journal, April 2014, Wiley

    Professor Luc Brunsveld

  10. Subcellular Fractionation and Localization Studies Reveal a Direct Interaction of the Fragile X Mental Retardation Protein (FMRP) with Nucleolin

    Article • PLoS ONE, March 2014, PLOS

    Professor Luc Brunsveld

  11. Solution structure of a cucurbit[8]uril induced compact supramolecular protein dimer

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Luc Brunsveld

  12. Synthetic Biology

    Article • January 2014

    Professor Luc Brunsveld

  13. Chapter 2. Use of synthetic biology techniques to site-selective introduce posttranslational modifications in proteins

    Article • January 2014, Royal Society of Chemistry

    Professor Luc Brunsveld

  14. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites

    Article • Molecular Pharmacology, December 2013, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor Luc Brunsveld

  15. Pharmaceutical implications of helix length control in helix-mediated protein–protein interactions

    Article • Future Medicinal Chemistry, December 2013, Future Science

    Professor Luc Brunsveld

  16. Self‐Assembled Fluorescent Organic Nanoparticles for Live‐Cell Imaging

    Article • Chemistry - A European Journal, October 2013, Wiley

    Professor Luc Brunsveld

  17. Multivalent Protein Assembly Using Monovalent Self-Assembling Building Blocks

    Article • International Journal of Molecular Sciences, October 2013, MDPI AG

    Professor Luc Brunsveld

  18. PNA-Induced Assembly of Fluorescent Proteins Using DNA as a Framework

    Article • Bioconjugate Chemistry, August 2013, American Chemical Society (ACS)

    Professor Luc Brunsveld

  19. Modular Columnar Supramolecular Polymers as Scaffolds for Biomedical Applications

    Article • Chemistry - A European Journal, July 2013, Wiley

    Professor Luc Brunsveld

  20. Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface

    Article • Proceedings of the National Academy of Sciences, May 2013, Proceedings of the National Academy of Sciences

    Professor Luc Brunsveld

  21. Self‐Assembling Multivalency – Supramolecular Polymers Assembled from Monovalent Mannose‐Labelled Discotic Molecules

    Article • European Journal of Organic Chemistry, April 2013, Wiley

    Professor Luc Brunsveld

  22. Proline Primed Helix Length as a Modulator of the Nuclear Receptor–Coactivator Interaction

    Article • Journal of the American Chemical Society, March 2013, American Chemical Society (ACS)

    Professor Luc Brunsveld

  23. Immobilization of Ferrocene-Modified SNAP-Fusion Proteins

    Article • International Journal of Molecular Sciences, February 2013, MDPI AG

    Professor Luc Brunsveld

  24. SH3-mediated targeting of Wrch1/RhoU by multiple adaptor proteins

    Article • Biological Chemistry, February 2013, De Gruyter

    Professor Luc Brunsveld

  25. Supramolecular Control of Enzyme Activity through Cucurbit[8]uril‐Mediated Dimerization

    Article • Angewandte Chemie, January 2013, Wiley

    Professor Luc Brunsveld

  26. Supramolecular Control of Enzyme Activity through Cucurbit[8]uril‐Mediated Dimerization

    Article • Angewandte Chemie International Edition, January 2013, Wiley

    Professor Luc Brunsveld

  27. Supramolecular control of cell adhesion via ferrocene–cucurbit[7]uril host–guest binding on gold surfaces

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Professor Luc Brunsveld

  28. Structure–activity relationship studies of miniproteins targeting the androgen receptor–coactivator interaction

    Article • MedChemComm, January 2013, Royal Society of Chemistry

    Professor Luc Brunsveld

  29. Supramolecular chemical biology; bioactive synthetic self-assemblies

    Article • Organic & Biomolecular Chemistry, January 2013, Royal Society of Chemistry

    Professor Luc Brunsveld

  30. Dynamic and bio-orthogonal protein assembly along a supramolecular polymer

    Article • Chemical Science, January 2013, Royal Society of Chemistry

    Professor Luc Brunsveld

  31. Stabilization and Inhibition of Protein–Protein Interactions: The 14-3-3 Case Study

    Article • ACS Chemical Biology, December 2012, American Chemical Society (ACS)

    Professor Luc Brunsveld

  32. Supramolecularly Oriented Immobilization of Proteins Using Cucurbit[8]uril

    Article • Langmuir, November 2012, American Chemical Society (ACS)

    Professor Luc Brunsveld

  33. Reversible and Oriented Immobilization of Ferrocene-Modified Proteins

    Article • Journal of the American Chemical Society, November 2012, American Chemical Society (ACS)

    Professor Luc Brunsveld

  34. Targeting alpha-helix based protein interactions; nuclear receptors as a case study

    Article • October 2012, Royal Society of Chemistry

    Professor Luc Brunsveld

  35. A facile strategy to prevent trifluoroacetylation of N-terminal proline peptides

    Article • Tetrahedron Letters, August 2012, Elsevier

    Professor Luc Brunsveld

  36. Supramolecular Polymers as Dynamic Multicomponent Cellular Uptake Carriers

    Article • Journal of the American Chemical Society, May 2012, American Chemical Society (ACS)

    Professor Luc Brunsveld

  37. Chemical Genomics and Proteomics: Reviews and Protocols. Edited by Edward D. Zanders.

    Article • ChemMedChem, April 2012, Wiley

    Professor Luc Brunsveld

  38. Directed Supramolecular Surface Assembly of SNAP‐tag Fusion Proteins

    Article • Chemistry - A European Journal, April 2012, Wiley

    Professor Luc Brunsveld

  39. Chemical‐Biological Exploration of the Limits of the Ras De‐ and Repalmitoylating Machinery

    Article • ChemBioChem, April 2012, Wiley

    Professor Luc Brunsveld

  40. Positional screening and NMR structure determination of side-chain-to-side-chain cyclized β3-peptides

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Professor Luc Brunsveld

  41. Cucurbit[8]uril-mediated protein homotetramerization

    Article • Chemical Science, January 2012, Royal Society of Chemistry

    Professor Luc Brunsveld

  42. Estrogen Receptor α/β–cofactor motif interactions; interplay of tyrosine 537/488 phosphorylation and LXXLL motifs

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Professor Luc Brunsveld

  43. Pre- and Postfunctionalized Self-Assembled π-Conjugated Fluorescent Organic Nanoparticles for Dual Targeting

    Article • Journal of the American Chemical Society, September 2011, American Chemical Society (ACS)

    Professor Luc Brunsveld

  44. Investigational study of tamoxifen phase I metabolites using chromatographic and spectroscopic analytical techniques

    Article • Journal of Pharmaceutical and Biomedical Analysis, June 2011, Elsevier

    Professor Luc Brunsveld

  45. Analysis of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and Its Phase I and Phase II Metabolites in Mouse Urine Using LC–UV–MS–MS

    Article • Chromatographia, May 2011, Springer Science + Business Media

    Professor Luc Brunsveld

  46. Semiconductive, One‐Dimensional, Self‐Assembled Nanostructures Based on Oligopeptides with π‐Conjugated Segments

    Article • Chemistry - A European Journal, March 2011, Wiley

    Professor Luc Brunsveld

  47. Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold-Detection Approach

    Article • Journal of Medicinal Chemistry, March 2011, American Chemical Society (ACS)

    Professor Luc Brunsveld

  48. Proteinassembly along a supramolecular wire

    Article • Chemical Communications, January 2011, Royal Society of Chemistry

    Professor Luc Brunsveld

  49. Cucurbit[8]uril induced heterodimerization of methylviologen and naphthalene functionalized proteins

    Article • Chemical Communications, January 2011, Royal Society of Chemistry

    Professor Luc Brunsveld

  50. Strong supramolecular control over protein self-assembly using a polyamine decorated β-cyclodextrin as synthetic recognition element

    Article • Journal of Materials Chemistry, January 2011, Royal Society of Chemistry

    Professor Luc Brunsveld

  51. An on-bead assay for the identification of non-natural peptides targeting the Androgen Receptor–cofactor interaction

    Article • Bioorganic & Medicinal Chemistry, January 2011, Elsevier

    Professor Luc Brunsveld

  52. Synthesis and Crystal Structure of a Phosphorylated Estrogen Receptor Ligand Binding Domain

    Article • ChemBioChem, October 2010, Wiley

    Professor Luc Brunsveld

  53. Synthesis of the Rheb and K‐Ras4B GTPases

    Article • Angewandte Chemie, August 2010, Wiley

    Professor Luc Brunsveld

  54. Synthesis of the Rheb and K‐Ras4B GTPases

    Article • Angewandte Chemie International Edition, August 2010, Wiley

    Professor Luc Brunsveld

  55. Solid‐Phase Synthesis of Lipidated Ras Peptides Employing the Ellman Sulfonamide Linker

    Article • Chemistry - A European Journal, August 2010, Wiley

    Professor Luc Brunsveld

  56. Small-molecule inhibition of APT1 affects Ras localization and signaling

    Article • April 2010, Nature

    Professor Luc Brunsveld

  57. The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins

    Article • Cell, April 2010, Elsevier

    Professor Luc Brunsveld

  58. Strong and Reversible Monovalent Supramolecular Protein Immobilization

    Article • ChemBioChem, January 2010, Wiley

    Professor Luc Brunsveld

  59. Protein Dimerization Induced by Supramolecular Interactions with Cucurbit[8]uril

    Article • Angewandte Chemie, January 2010, Wiley

    Professor Luc Brunsveld

  60. Protein Dimerization Induced by Supramolecular Interactions with Cucurbit[8]uril

    Article • Angewandte Chemie International Edition, January 2010, Wiley

    Professor Luc Brunsveld

  61. Phage display selection of miniprotein binders of the Estrogen Receptor

    Article • Chemical Communications, January 2010, Royal Society of Chemistry

    Professor Luc Brunsveld

  62. Combining supramolecular chemistry with biology

    Article • Chemical Society Reviews, January 2010, Royal Society of Chemistry

    Professor Luc Brunsveld

  63. Modulation of Protein Dimerization by a Supramolecular Host–Guest System

    Article • Chemistry - A European Journal, September 2009, Wiley

    Professor Luc Brunsveld

  64. Perturbation of Estrogen Receptor α Localization with Synthetic Nona-Arginine LXXLL-Peptide Coactivator Binding Inhibitors

    Article • Chemistry & Biology, July 2009, Elsevier

    Professor Luc Brunsveld

  65. Bioactivity-guided mapping and navigation of chemical space

    Article • June 2009

    Professor Luc Brunsveld

  66. A Supramolecular Polymer as a Self‐Assembling Polyvalent Scaffold

    Article • Angewandte Chemie, March 2009, Wiley

    Professor Luc Brunsveld

  67. A Supramolecular Polymer as a Self‐Assembling Polyvalent Scaffold

    Article • Angewandte Chemie International Edition, March 2009, Wiley

    Professor Luc Brunsveld

  68. Influence of the Lipidation Motif on the Partitioning and Association of N-Ras in Model Membrane Subdomains

    Article • Journal of the American Chemical Society, January 2009, American Chemical Society (ACS)

    Professor Luc Brunsveld

  69. Computational design, synthesis, and evaluation of miniproteins as androgen receptor coactivator mimics

    Article • Chemical Communications, January 2009, Royal Society of Chemistry

    Professor Luc Brunsveld

  70. Membrane binding of lipidated Ras peptides and proteins — The structural point of view

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, January 2009, Elsevier

    Professor Luc Brunsveld

  71. Mapping the Isoprenoid Binding Pocket of PDEδ by a Semisynthetic, Photoactivatable N‐Ras Lipoprotein

    Article • ChemBioChem, December 2008, Wiley

    Professor Luc Brunsveld

  72. Comparison of Design Strategies for Promotion of β‐Peptide 14‐Helix Stability in Water

    Article • ChemBioChem, September 2008, Wiley

    Professor Luc Brunsveld

  73. Structures of RabGGTase–substrate/product complexes provide insights into the evolution of protein prenylation

    Article • The EMBO Journal, August 2008, Springer Science + Business Media

    Professor Luc Brunsveld

  74. Lipidated peptide synthesis

    Article • May 2008, Wiley

    Professor Luc Brunsveld

  75. Racemization-Free Synthesis of S-Alkylated Cysteines via Thiol-ene Reaction

    Article • The Journal of Organic Chemistry, April 2008, American Chemical Society (ACS)

    Professor Luc Brunsveld

  76. Stable helical peptoids via covalent side chain to side chain cyclization

    Article • Organic & Biomolecular Chemistry, January 2008, Royal Society of Chemistry

    Professor Luc Brunsveld

  77. Synthesis of a fluorescent analogue of geranylgeranyl pyrophosphate and its use in a high-throughput fluorometric assay for Rab geranylgeranyltransferase

    Article • Nature Protocols, October 2007, Springer Science + Business Media

    Professor Luc Brunsveld

  78. A Synthetic Supramolecular Construct Modulating Protein Assembly in Cells

    Article • Angewandte Chemie International Edition, February 2007, Wiley

    Professor Luc Brunsveld

  79. A Synthetic Supramolecular Construct Modulating Protein Assembly in Cells

    Article • Angewandte Chemie, February 2007, Wiley

    Professor Luc Brunsveld

  80. Lipidierte Ras‐ und Rab‐Peptide und ‐Proteine: Synthese, Struktur und Funktion

    Article • Angewandte Chemie, October 2006, Wiley

    Professor Luc Brunsveld

  81. Lipidated Ras and Rab Peptides and Proteins—Synthesis, Structure, and Function

    Article • Angewandte Chemie International Edition, October 2006, Wiley

    Professor Luc Brunsveld

  82. Synthesis of palmitoylated Ras-peptides and -proteins

    Article • Methods, October 2006, Elsevier

    Professor Luc Brunsveld

  83. Therapeutic intervention based on protein prenylation and associated modifications

    Article • Nature Chemical Biology, September 2006, Springer Science + Business Media

    Professor Luc Brunsveld

  84. Stable Helicalβ3-Peptides in Water via Covalent Bridging of Side Chains

    Article • Organic Letters, September 2006, American Chemical Society (ACS)

    Professor Luc Brunsveld

  85. Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling

    Article • The EMBO Journal, January 2006, Springer Science + Business Media

    Professor Luc Brunsveld

  86. Synthesis of Functionalized Rab GTPases by a Combination of Solution‐ or Solid‐Phase Lipopeptide Synthesis with Expressed Protein Ligation

    Article • Chemistry - A European Journal, April 2005, Wiley

    Professor Luc Brunsveld

  87. Chemical biology of protein lipidation: semi-synthesis and structure elucidation of prenylated RabGTPases

    Article • Organic & Biomolecular Chemistry, January 2005, Royal Society of Chemistry

    Professor Luc Brunsveld

  88. Application of Protein Semisynthesis for the Construction of Functionalized Posttranslationally Modified Rab GTPases

    Article • January 2005, Elsevier

    Professor Luc Brunsveld

  89. Supramolecular Control over Donor−Acceptor Photoinduced Charge Separation

    Article • Journal of the American Chemical Society, July 2004, American Chemical Society (ACS)

    Professor Luc Brunsveld

  90. Supramolecular polymers: from scientific curiosity to technological reality

    Article • Macromolecular Symposia, October 2003, Wiley

    Professor Luc Brunsveld

  91. Hierarchical formation of helical supramolecular polymers via stacking of hydrogen-bonded pairs in water

    Article • Proceedings of the National Academy of Sciences, April 2002, Proceedings of the National Academy of Sciences

    Professor Luc Brunsveld

  92. Supramolecular Polymers

    Article • Chemical Reviews, November 2001, American Chemical Society (ACS)

    Professor Luc Brunsveld

  93. Cooperativity in the Folding of Helicalm-Phenylene Ethynylene Oligomers Based upon the `Sergeants-and-Soldiers' Principle

    Article • Chemistry - A European Journal, October 2001, Wiley

    Professor Luc Brunsveld

  94. Self-Assembly of Folded m-Phenylene Ethynylene Oligomers into Helical Columns

    Article • Journal of the American Chemical Society, July 2001, American Chemical Society (ACS)

    Professor Luc Brunsveld

  95. Helical Transition and Growth of Supramolecular Assemblies of Chiral Discotic Molecules

    Article • Langmuir, November 2000, American Chemical Society (ACS)

    Professor Luc Brunsveld

  96. Hierarchical Growth of Chiral Self-Assembled Structures in Protic Media

    Article • Journal of the American Chemical Society, June 2000, American Chemical Society (ACS)

    Professor Luc Brunsveld

  97. Conformational Ordering of Apolar, Chiral m-Phenylene Ethynylene Oligomers

    Article • Organic Letters, May 2000, American Chemical Society (ACS)

    Professor Luc Brunsveld

  98. Supramolecular Polymers

    Article • MRS Bulletin, April 2000, Springer Science + Business Media

    Professor Luc Brunsveld

  99. Twist Sense Bias Induced by Chiral Side Chains in Helically Folded Oligomers

    Article • Angewandte Chemie, January 2000, Wiley

    Professor Luc Brunsveld

  100. Twist Sense Bias Induced by Chiral Side Chains in Helically Folded Oligomers

    Article • Angewandte Chemie International Edition, January 2000, Wiley

    Professor Luc Brunsveld

  101. Chirality amplification in dynamic helical columns in water

    Article • Chemical Communications, January 2000, Royal Society of Chemistry

    Professor Luc Brunsveld

  102. Chiral Amplification in Columns of Self-Assembled N,N',N"-Tris((S)-3,7-dimethyloctyl)benzene-1,3,5-tricarboxamide in Dilute Solution.

    Article • Chemistry Letters, January 2000, Chemical Society of Japan

    Professor Luc Brunsveld

  103. The Influence of Lithium Perchlorate on Discotic Liquid Crystals and the Ion Conduction of their Mixtures

    Article • Molecular Crystals and Liquid Crystals Science and Technology Section A Molecular Crystals and Liquid Crystals, August 1999, Taylor & Francis

    Professor Luc Brunsveld

  104. Targeting the Nuclear Receptor–Cofactor Interaction

    Article • Wiley

    Professor Luc Brunsveld

  105. Chiral Discotic Molecules: Expression and Amplification of Chirality

    Article • Wiley

    Professor Luc Brunsveld