All Stories

  1. 3D imaging of Sox2 enhancer clusters in embryonic stem cells
  2. Evolved differences in larval social behavior mediated by novel pheromones
  3. Integrated action of pheromone signals in promoting courtship behavior in male mice
  4. Bright Building Blocks for Chemical Biology
  5. Single-molecule tracking of the transcription cycle by sub-second RNA detection
  6. Decoupled Roles for the Atypical, Bifurcated Binding Pocket of the ybfF Hydrolase
  7. Rhodium(III)-Catalyzed Indazole Synthesis by C–H Bond Functionalization and Cyclative Capture
  8. Carbofluoresceins and Carborhodamines as Scaffolds for High-Contrast Fluorogenic Probes
  9. The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima
  10. Excitation Spectra and Brightness Optimization of Two-Photon Excited Probes
  11. Advances in the chemistry of small molecule fluorescent probes
  12. Synthesis of Rhodamines from Fluoresceins Using Pd-Catalyzed C–N Cross-Coupling
  13. Facile and General Synthesis of Photoactivatable Xanthene Dyes
  14. Cellular Uptake of Ribonuclease A Relies on Anionic Glycans
  15. Onconase cytotoxicity relies on the distribution of its positive charge
  16. Fluorogenic affinity label for the facile, rapid imaging of proteins in live cells
  17. A highly sensitive fluorogenic probe for cytochrome P450 activity in live cells
  18. Ester Bonds in Prodrugs
  19. Bright Ideas for Chemical Biology
  20. Trimethyl Lock: A Stable Chromogenic Substrate for Esterases
  21. Intraspecies Regulation of Ribonucleolytic Activity
  22. Cytotoxic Ribonucleases:  The Dichotomy of Coulombic Forces
  23. Tuning the pKaof Fluorescein to Optimize Binding Assays
  24. Latent Blue and Red Fluorophores Based on the Trimethyl Lock
  25. Fluorogenic Label for Biomolecular Imaging