All Stories

  1. Two cases of erosive oral lichen planus with autoantibodies to desmoglein 3

    Article • The Journal of Dermatology, July 2016, Wiley

    Dr KEN NATSUGA

  2. Early severe pachyonychia congenita subtype PC-K6a with a novel mutation in the KRT6A gene

    Article • Journal of the European Academy of Dermatology and Venereology, July 2016, Wiley

    Dr KEN NATSUGA

  3. Autoantibody profile differentiates between inflammatory and non-inflammatory bullous pemphigoid

    Article • Journal of Investigative Dermatology, July 2016, Elsevier

    Dr KEN NATSUGA

  4. Galectin-6 is a novel skin anti-microbial peptide that is modulated by the skin barrier and microbiome

    Article • Journal of Dermatological Science, June 2016, Elsevier

    Dr KEN NATSUGA, Professor Fiona M Watt

  5. Epitope-Dependent Pathogenicity of Antibodies Targeting a Major Bullous Pemphigoid Autoantigen Collagen XVII/BP180

    Article • Journal of Investigative Dermatology, May 2016, Elsevier

    Dr KEN NATSUGA

  6. Pyoderma Gangrenosum Associated with Acute Respiratory Distress Syndrome

    Article • The American Journal of Medicine, February 2016, Elsevier

    Dr KEN NATSUGA

  7. Increased Bacterial Load and Expression of Antimicrobial Peptides in Skin of Barrier-Deficient Mice with Reduced Cancer Susceptibility

    Article • Journal of Investigative Dermatology, January 2016, Elsevier

    Dr KEN NATSUGA, Professor Fiona M Watt

  8. Epidermolysis Bullosa Acquisita Develops in Dominant Dystrophic Epidermolysis Bullosa

    Article • Journal of Investigative Dermatology, January 2016, Elsevier

    Dr KEN NATSUGA

  9. Anti-laminin-gamma 1 Pemphigoid with Generalized Pustular Psoriasis and Psoriasis Vulgaris

    Article • Acta Dermato Venereologica, January 2016, Acta Dermato-Venereologica

    Dr KEN NATSUGA

  10. Extracellular cleavage of collagen XVII is essential for correct cutaneous basement membrane formation

    Article • Human Molecular Genetics, November 2015, Oxford University Press (OUP)

    Dr KEN NATSUGA

  11. Mucocutaneous pyoderma gangrenosum due to trisomy 8 neutrophilic infiltrates in a patient with myelodysplastic syndrome

    Article • British Journal of Dermatology, November 2015, Wiley

    Dr KEN NATSUGA

  12. Concomitant neoplasms in the skin and stomach unveil the role of type IV collagen and E-cadherin in mucin core protein 5AC expression in vivo

    Article • British Journal of Dermatology, November 2015, Wiley

    Dr KEN NATSUGA

  13. Generalized acute subcutaneous edema as a rare cutaneous manifestation of severe dermatomyositis

    Article • Journal of the European Academy of Dermatology and Venereology, November 2015, Wiley

    Dr KEN NATSUGA

  14. Epitope-Dependent Pathogenicity of Antibodies Targeting a Major Pemphigoid Autoantigen, BP180

    Article • Oral Surgery Oral Medicine Oral Pathology and Oral Radiology, September 2015, Elsevier

    Dr KEN NATSUGA

  15. Plasma cell cheilitis extending beyond vermillion border

    Article • The Journal of Dermatology, June 2015, Wiley

    Dr KEN NATSUGA

  16. Context-Dependent Regulation of Collagen XVII Ectodomain Shedding in Skin

    Article • American Journal Of Pathology, May 2015, Elsevier

    Dr KEN NATSUGA

  17. mTOR expression correlates with invasiveness and progression of extramammary Paget's disease

    Article • Journal of the European Academy of Dermatology and Venereology, April 2015, Wiley

    Dr KEN NATSUGA

  18. In vivo analysis of IgE autoantibodies in bullous pemphigoid: A study of 100 cases

    Article • Journal of Dermatological Science, April 2015, Elsevier

    Dr KEN NATSUGA

  19. Plectin-related skin diseases

    Article • Journal of Dermatological Science, March 2015, Elsevier

    Dr KEN NATSUGA

  20. Skipped exon inCOL7A1determines the clinical phenotypes of dystrophic epidermolysis bullosa

    Article • British Journal of Dermatology, February 2015, Oxford University Press (OUP)

    Dr KEN NATSUGA

  21. Verrucous hyperplasia associated with neuropathy from schistorrhachis

    Article • Journal of the European Academy of Dermatology and Venereology, February 2015, Wiley

    Dr KEN NATSUGA

  22. Mucosal hyperpigmentation from prophylactic minocycline for EGFR inhibitor

    Article • Journal of the European Academy of Dermatology and Venereology, January 2015, Wiley

    Dr KEN NATSUGA

  23. Bowen's disease on the palm presents refractory skin erosion without erythematous plaque

    Article • The Journal of Dermatology, December 2014, Wiley

    Dr KEN NATSUGA

  24. Metal implant-induced skin ulcer mimicking scrofuloderma

    Article • Journal of the European Academy of Dermatology and Venereology, November 2014, Wiley

    Dr KEN NATSUGA

  25. Anti-BP180-type mucous membrane pemphigoid: report of two cases

    Article • Odontology, October 2014, Springer Science + Business Media

    Dr KEN NATSUGA

  26. BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions

    Article • Stem Cell Reports, October 2014, Elsevier

    Dr KEN NATSUGA, Professor Fiona M Watt

  27. Bullous Pemphigoid Autoantibodies Directly Induce Blister Formation without Complement Activation

    Article • The Journal of Immunology, September 2014, The American Association of Immunologists

    Dr KEN NATSUGA

  28. A recurrent ‘hot spot’ glycine substitution mutation, G2043R in COL7A1, induces dominant dystrophic epidermolysis bullosa associated with intracytoplasmic accumulation of pro-collagen VII

    Article • Journal of Dermatological Science, July 2014, Elsevier

    Dr KEN NATSUGA

  29. Solitary fibrous tumour fluctuating in size with menstrual cycle

    Article • Clinical and Experimental Dermatology, July 2014, Oxford University Press (OUP)

    Dr KEN NATSUGA

  30. Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility

    Article • eLife, May 2014, eLife

    Dr KEN NATSUGA, Professor Fiona M Watt

  31. Paper-Based ELISA for the Detection of Autoimmune Antibodies in Body Fluid—The Case of Bullous Pemphigoid

    Article • Analytical Chemistry, April 2014, American Chemical Society (ACS)

    Dr KEN NATSUGA

  32. Ultrasound B-mode and elastographic findings of angiomatoid fibrous histiocytoma

    Article • Clinical and Experimental Dermatology, April 2014, Oxford University Press (OUP)

    Dr KEN NATSUGA

  33. Epidermal Barriers

    Article • Cold Spring Harbor Perspectives in Medicine, April 2014, Cold Spring Harbor Laboratory Press

    Dr KEN NATSUGA

  34. Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors

    Article • Proceedings of the National Academy of Sciences, March 2014, Proceedings of the National Academy of Sciences

    Dr KEN NATSUGA, Professor Fiona M Watt

  35. Dermoscopic Features of Plasma Cell Cheilitis and Actinic Cheilitis

    Article • Acta Dermato Venereologica, January 2014, Acta Dermato-Venereologica

    Dr KEN NATSUGA

  36. Extensive Erythema and Hyperkeratosis on the Extremities and Lumbar Area as an Unusual Mani-festation of Nagashima-type Palmoplantar Keratosis

    Article • Acta Dermato Venereologica, January 2014, Acta Dermato-Venereologica

    Dr KEN NATSUGA

  37. Epidermolysis Bullosa Simplex

    Article • February 2013, IntechOpen

    Dr KEN NATSUGA

  38. c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis

    Article • Cell Reports, February 2013, Elsevier

    Dr KEN NATSUGA, Professor Fiona M Watt

  39. Antibodies to epitopes on collagen XVII (COL17) induce skin fragility in COL17-humanized mice in a complement-dependent and -independent way

    Article • Journal of Dermatological Science, February 2013, Elsevier

    Dr KEN NATSUGA

  40. Epidermal Wnt/beta-catenin signalling promotes dermal adipocyte differentiation during hair follicle morphogenesis and regeneration

    Article • Journal of Dermatological Science, February 2013, Elsevier

    Dr KEN NATSUGA

  41. A Novel Keratin 5 Mutation in an African Family with Epidermolysis Bullosa Simplex Indicates the Importance of the Amino Acid Located at the Boundary Site Between the H1 and Coil 1A Domains

    Article • Acta Dermato Venereologica, January 2013, Acta Dermato-Venereologica

    Dr KEN NATSUGA

  42. The β9 Loop Domain of PA-PLA1α Has a Crucial Role in Autosomal Recessive Woolly Hair/Hypotrichosis

    Article • Journal of Investigative Dermatology, August 2012, Elsevier

    Dr KEN NATSUGA

  43. 716 Chemical Carcinogenesis in Mice With a Defective Epidermal Barrier – Exploring the Connection Between Skin Barrier and Cancer Susceptibility

    Article • European Journal of Cancer, July 2012, Elsevier

    Dr KEN NATSUGA

  44. Antibodies to Pathogenic Epitopes on Type XVII Collagen Cause Skin Fragility in a Complement-Dependent and -Independent Manner

    Article • The Journal of Immunology, April 2012, The American Association of Immunologists

    Dr KEN NATSUGA

  45. Mucous membrane pemphigoid with generalized blisters: IgA and IgG autoantibodies target both laminin‐332 and type XVII collagen

    Article • British Journal of Dermatology, March 2012, Oxford University Press (OUP)

    Dr KEN NATSUGA

  46. Possible modifier effects of keratin 17 gene mutation on keratitis-ichthyosis-deafness syndrome

    Article • British Journal of Dermatology, January 2012, Oxford University Press (OUP)

    Dr KEN NATSUGA

  47. Subepidermal blistering disease with 3 distinct autoantibodies: Anti-BP230, anti-laminin gamma-1, and anti-laminin-332

    Article • Journal of the American Academy of Dermatology, October 2011, Elsevier

    Dr KEN NATSUGA

  48. Consequences of Two Different Amino-Acid Substitutions at the Same Codon in KRT14 Indicate Definitive Roles of Structural Distortion in Epidermolysis Bullosa Simplex Pathogenesis

    Article • Journal of Investigative Dermatology, September 2011, Elsevier

    Dr KEN NATSUGA

  49. Malignant skin tumours in patients with inherited ichthyosis

    Article • British Journal of Dermatology, July 2011, Oxford University Press (OUP)

    Dr KEN NATSUGA

  50. DNA‐based prenatal diagnosis of plectin‐deficient epidermolysis bullosa simplex associated with pyloric atresia

    Article • International Journal of Dermatology, March 2011, Wiley

    Dr KEN NATSUGA

  51. Type XVII collagen ELISA indices significantly decreased after bullous pemphigoid remission

    Article • International Journal of Dermatology, February 2011, Wiley

    Dr KEN NATSUGA

  52. Childhood subepidermal blistering disease with autoantibodies to type VII collagen and laminin-332

    Article • British Journal of Dermatology, January 2011, Oxford University Press (OUP)

    Dr KEN NATSUGA

  53. Expression of exon-8-skipped kindlin-1 does not compensate for defects of Kindler syndrome

    Article • Journal of Dermatological Science, January 2011, Elsevier

    Dr KEN NATSUGA

  54. Spontaneous Remission of Solitary-Type Infantile Myofibromatosis

    Article • Case Reports in Dermatology, January 2011, Karger Publishers

    Dr KEN NATSUGA

  55. Human IgG1 Monoclonal Antibody against Human Collagen 17 Noncollagenous 16A Domain Induces Blisters via Complement Activation in Experimental Bullous Pemphigoid Model

    Article • The Journal of Immunology, November 2010, The American Association of Immunologists

    Dr KEN NATSUGA

  56. Complete Paternal Isodisomy of Chromosome 17 in Junctional Epidermolysis Bullosa with Pyloric Atresia

    Article • Journal of Investigative Dermatology, November 2010, Elsevier

    Dr KEN NATSUGA

  57. A founder effect of c.1938delC in ITGB4 underlies junctional epidermolysis bullosa and its application for prenatal testing

    Article • Experimental Dermatology, October 2010, Wiley

    Dr KEN NATSUGA

  58. Plectin deficiency leads to both muscular dystrophy and pyloric atresia in epidermolysis bullosa simplex

    Article • Human Mutation, July 2010, Hindawi Publishing Corporation

    Dr KEN NATSUGA

  59. Bone marrow transplantation restores epidermal basement membrane protein expression and rescues epidermolysis bullosa model mice

    Article • Proceedings of the National Academy of Sciences, July 2010, Proceedings of the National Academy of Sciences

    Dr KEN NATSUGA

  60. Epidermolysis Bullosa in Japan

    Article • Dermatologic Clinics, April 2010, Elsevier

    Dr KEN NATSUGA

  61. Plectin expression patterns determine two distinct subtypes of epidermolysis bullosa simplex

    Article • Human Mutation, March 2010, Hindawi Publishing Corporation

    Dr KEN NATSUGA

  62. Animal Models of Epidermolysis Bullosa

    Article • Dermatologic Clinics, January 2010, Elsevier

    Dr KEN NATSUGA

  63. PrevalentLIPHfounder mutations lead to loss of P2Y5 activation ability of PA-PLA1α in autosomal recessive hypotrichosis

    Article • Human Mutation, January 2010, Hindawi Publishing Corporation

    Dr KEN NATSUGA

  64. Localized Linear IgA/IgG Bullous Dermatosis

    Article • Acta Dermato Venereologica, January 2010, Acta Dermato-Venereologica

    Dr KEN NATSUGA

  65. Response of Intractable Skin Ulcers in Recessive Dystrophic Epidermolysis Bullosa Patients to an Allogeneic Cultured Dermal Substitute

    Article • Acta Dermato Venereologica, January 2010, Acta Dermato-Venereologica

    Dr KEN NATSUGA

  66. Keratinocyte-/Fibroblast-Targeted Rescue of Col7a1-Disrupted Mice and Generation of an Exact Dystrophic Epidermolysis Bullosa Model Using a Human COL7A1 Mutation

    Article • American Journal Of Pathology, December 2009, Elsevier

    Dr KEN NATSUGA

  67. Secondary syphilis mimicking warts in an HIV-positive patient

    Article • Sexually Transmitted Infections, October 2009, BMJ

    Dr KEN NATSUGA

  68. Circulating IgA and IgE autoantibodies in antilaminin-332 mucous membrane pemphigoid

    Article • British Journal of Dermatology, September 2009, Oxford University Press (OUP)

    Dr KEN NATSUGA

  69. A Novel Humanized Neonatal Autoimmune Blistering Skin Disease Model Induced by Maternally Transferred Antibodies

    Article • The Journal of Immunology, August 2009, The American Association of Immunologists

    Dr KEN NATSUGA

  70. Widespread keratosis follicularis squamosa

    Article • Clinical and Experimental Dermatology, June 2009, Oxford University Press (OUP)

    Dr KEN NATSUGA

  71. Pemphigus foliaceus associated with oesophageal cancer

    Article • Journal of the European Academy of Dermatology and Venereology, March 2009, Wiley

    Dr KEN NATSUGA

  72. Autoantibodies against type XVII collagen C-terminal domain in a patient with bullous pemphigoid associated with psoriasis vulgaris

    Article • British Journal of Dermatology, February 2009, Oxford University Press (OUP)

    Dr KEN NATSUGA

  73. Morphological and genetic analysis of steatocystoma multiplex in an Asian family with pachyonychia congenita type 2 harbouring aKRT17missense mutation

    Article • British Journal of Dermatology, February 2009, Oxford University Press (OUP)

    Dr KEN NATSUGA

  74. Type XVII Collagen is a Key Player in Tooth Enamel Formation

    Article • American Journal Of Pathology, January 2009, Elsevier

    Dr KEN NATSUGA

  75. Usefulness of thermography techniques for evaluating the disease activity in Kimura’s disease

    Article • Clinical and Experimental Dermatology, November 2008, Oxford University Press (OUP)

    Dr KEN NATSUGA

  76. Cutaneous pemphigus vulgaris with skin features similar to the classic mucocutaneous type: a case report and review of the literature

    Article • Clinical and Experimental Dermatology, November 2008, Oxford University Press (OUP)

    Dr KEN NATSUGA

  77. Acquired perforating dermatosis appearing as elastosis perforans serpiginosa and perforating folliculitis

    Article • Clinical and Experimental Dermatology, September 2008, Oxford University Press (OUP)

    Dr KEN NATSUGA

  78. Leukaemic dissemination of Merkel cell carcinoma in a patient with systemic lupus erythematosus

    Article • Clinical and Experimental Dermatology, May 2008, Oxford University Press (OUP)

    Dr KEN NATSUGA

  79. Precursor B-cell lymphoblastic lymphoma presented with intraocular involvement and unusual skin manifestations

    Article • Annals of Hematology, March 2008, Springer Science + Business Media

    Dr KEN NATSUGA

  80. Novel ABCA12 Mutations Identified in Two Cases of Non-Bullous Congenital Ichthyosiform Erythroderma Associated with Multiple Skin Malignant Neoplasia

    Article • Journal of Investigative Dermatology, November 2007, Elsevier

    Dr KEN NATSUGA

  81. Amicrobial pustulosis associated with IgA nephropathy and Sjögren's syndrome

    Article • Journal of the American Academy of Dermatology, September 2007, Elsevier

    Dr KEN NATSUGA

  82. Non‐Hodgkin lymphoma preceded by recalcitrant eczema

    Article • European Journal Of Haematology, June 2007, Wiley

    Dr KEN NATSUGA

  83. Keratoacanthoma developing on nevus sebaceous in a child

    Article • Journal of the American Academy of Dermatology, February 2007, Elsevier

    Dr KEN NATSUGA

  84. Mycosis Fungoides Bullosa

    Article • Archives of Dermatology, June 2006, American Medical Association (AMA)

    Dr KEN NATSUGA

  85. Severe cholinergic urticaria successfully treated with scopolamine butylbromide in addition to antihistamines

    Article • Clinical and Experimental Dermatology, June 2006, Oxford University Press (OUP)

    Dr KEN NATSUGA

  86. Two cases of atypical melanocytic lesions in recessive dystrophic epidermolysis bullosa infants

    Article • Clinical and Experimental Dermatology, November 2005, Oxford University Press (OUP)

    Dr KEN NATSUGA

  87. Ultrastructural Features of Trafficking Defects Are Pronounced in Melanocytic Nevus in Hermansky–Pudlak Syndrome Type 1

    Article • Journal of Investigative Dermatology, July 2005, Elsevier

    Dr KEN NATSUGA