All Stories

  1. Human Toxicity Caused by Indole and Indazole Carboxylate Synthetic Cannabinoid Receptor Agonists: From Horizon Scanning to Notification

    Article • Clinical Chemistry, October 2017, AACC

    Ian Hardcastle, David Wood

  2. Trifluoroethanol solvent facilitates selective N-7 methylation of purines

    Article • Organic & Biomolecular Chemistry, January 2013, Royal Society of Chemistry

    Ian Hardcastle

  3. Diaryl- and triaryl-pyrrole derivatives: inhibitors of the MDM2–p53 and MDMX–p53 protein–protein interactions

    Article • MedChemComm, January 2013, Royal Society of Chemistry

    Ian Hardcastle, Professor John Lunec

  4. Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Ian Hardcastle

  5. Versatile synthesis of functionalised dibenzothiophenes via Suzuki coupling and microwave-assisted ring closure

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    Ian Hardcastle

  6. Atropisomeric 8-arylchromen-4-ones exhibit enantioselective inhibition of the DNA-dependent protein kinase (DNA-PK)

    Article • Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry

    Ian Hardcastle

  7. Synthesis of sulfonamide-based kinase inhibitors from sulfonates by exploiting the abrogated SN2 reactivity of 2,2,2-trifluoroethoxysulfonates

    Article • Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry

    Ian Hardcastle

  8. Synthesis and biological evaluation of 5-substituted O4-alkylpyrimidines as CDK2 inhibitors

    Article • Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry

    Ian Hardcastle