All Stories

  1. Vortioxetine restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats

    Article • The International Journal of Neuropsychopharmacology, May 2014, Oxford University Press (OUP)

    Professor David A Morilak, Dr Alan Lars Pehrson

  2. THE CANNABINOID DICHOTOMY IN SCHIZOPHRENIA: FROM RISK FACTOR TO THERAPY

    Article • Schizophrenia Research, April 2014, Elsevier

    Professor David A Morilak

  3. A Novel Role for Brain Interleukin-6: Facilitation of Cognitive Flexibility in Rat Orbitofrontal Cortex

    Article • Journal of Neuroscience, January 2014, Society for Neuroscience

    Professor David A Morilak

  4. Jekyll and Hyde

    Article • January 2014, Elsevier

    Professor David A Morilak

  5. Exogenous prenatal corticosterone exposure mimics the effects of prenatal stress on adult brain stress response systems and fear extinction behavior

    Article • Psychoneuroendocrinology, November 2013, Elsevier

    Professor David A Morilak

  6. Influence of hypothalamic IL-6/gp130 receptor signaling on the HPA axis response to chronic stress

    Article • Psychoneuroendocrinology, July 2013, Elsevier

    Professor David A Morilak

  7. Effects of milnacipran on cognitive flexibility following chronic stress in rats

    Article • European Journal of Pharmacology, March 2013, Elsevier

    Professor David A Morilak

  8. Modulating the modulators: Interaction of brain norepinephrine and cannabinoids in stress

    Article • Experimental Neurology, December 2012, Elsevier

    Professor David A Morilak

  9. Too Much of a Good Thing: Blocking Noradrenergic Facilitation in Medial Prefrontal Cortex Prevents the Detrimental Effects of Chronic Stress on Cognition

    Article • Neuropsychopharmacology, November 2012, Springer Science + Business Media

    Professor David A Morilak

  10. Effects of chronic plus acute prolonged stress on measures of coping style, anxiety, and evoked HPA-axis reactivity

    Article • Neuropharmacology, November 2012, Elsevier

    Professor David A Morilak

  11. 86. Orbitofrontal IL-6 enhances reversal learning in the rat

    Article • Brain Behavior and Immunity, September 2012, Elsevier

    Professor David A Morilak

  12. 5-HT2A receptors in the orbitofrontal cortex facilitate reversal learning and contribute to the beneficial cognitive effects of chronic citalopram treatment in rats

    Article • The International Journal of Neuropsychopharmacology, October 2011, Oxford University Press (OUP)

    Professor David A Morilak

  13. Chronic intermittent cold stress sensitizes neuro-immune reactivity in the rat brain

    Article • Psychoneuroendocrinology, September 2011, Elsevier

    Professor David A Morilak

  14. Prenatal stress induces long term stress vulnerability, compromising stress response systems in the brain and impairing extinction of conditioned fear after adult stress

    Article • Neuroscience, September 2011, Elsevier

    Professor David A Morilak

  15. Stress modulation of cognitive and affective processes

    Article • Stress, July 2011, Taylor & Francis

    Professor David A Morilak

  16. Beneficial effects of desipramine on cognitive function of chronically stressed rats are mediated by α1-adrenergic receptors in medial prefrontal cortex

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, August 2010, Elsevier

    Professor David A Morilak

  17. A cognitive deficit induced in rats by chronic intermittent cold stress is reversed by chronic antidepressant treatment

    Article • The International Journal of Neuropsychopharmacology, February 2010, Oxford University Press (OUP)

    Professor David A Morilak

  18. Behavioural Assays to Model Cognitive and Affective Dimensions of Depression and Anxiety in Rats

    Article • Journal of Neuroendocrinology, September 2008, Wiley

    Professor David A Morilak

  19. S.20.05 Effects of chronic stress, monoamines and antidepressant drugs on cognitive function in prefrontal cortex

    Article • European Neuropsychopharmacology, August 2008, Elsevier

    Professor David A Morilak

  20. Chronic intermittent hypoxia sensitizes acute hypothalamic–pituitary–adrenal stress reactivity and Fos induction in the rat locus coeruleus in response to subsequent immobilization stress

    Article • Neuroscience, July 2008, Elsevier

    Professor David A Morilak

  21. Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats

    Article • Psychopharmacology, June 2008, Springer Science + Business Media

    Professor David A Morilak

  22. Norepinephrine Transporter Regulation Mediates the Long-Term Behavioral Effects of the Antidepressant Desipramine

    Article • Neuropsychopharmacology, April 2008, Springer Science + Business Media

    Professor David A Morilak

  23. Blockade of autoreceptor-mediated inhibition of norepinephrine release by atipamezole is maintained after chronic reuptake inhibition

    Article • The International Journal of Neuropsychopharmacology, August 2007, Oxford University Press (OUP)

    Professor David A Morilak

  24. Chronic Unpredictable Stress Induces a Cognitive Deficit and Anxiety-Like Behavior in Rats that is Prevented by Chronic Antidepressant Drug Treatment

    Article • Neuropsychopharmacology, April 2007, Springer Science + Business Media

    Professor David A Morilak

  25. Noradrenergic facilitation of shock-probe defensive burying in lateral septum of rats, and modulation by chronic treatment with desipramine

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, March 2007, Elsevier

    Professor David A Morilak

  26. Norepinephrine and stress

    Article • February 2007, Cambridge University Press

    Professor David A Morilak

  27. Chronic Treatment with Desipramine Improves Cognitive Performance of Rats in an Attentional Set-Shifting Test

    Article • Neuropsychopharmacology, November 2006, Springer Science + Business Media

    Professor David A Morilak

  28. Noradrenergic modulation of cognitive function in rat medial prefrontal cortex as measured by attentional set shifting capability

    Article • Neuroscience, January 2006, Elsevier

    Professor David A Morilak

  29. Role of brain norepinephrine in the behavioral response to stress

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, December 2005, Elsevier

    Professor David A Morilak

  30. Chronic Intermittent Cold Stress Sensitises the Hypothalamic‐Pituitary‐Adrenal Response to a Novel Acute Stress by Enhancing Noradrenergic Influence in the Rat Paraventricular Nucleus

    Article • Journal of Neuroendocrinology, October 2005, Wiley

    Professor David A Morilak

  31. Administration of the galanin antagonist M40 into lateral septum attenuates shock probe defensive burying behavior in rats

    Article • Neuropeptides, October 2005, Elsevier

    Professor David A Morilak

  32. One for all or one for one: does co-transmission unify the concept of a brain galanin “system” or clarify any consistent role in anxiety?

    Article • Neuropeptides, June 2005, Elsevier

    Professor David A Morilak

  33. Reduced Hypothalamic Vasopressin Secretion Underlies Attenuated Adrenocorticotropin Stress Responses in Pregnant Rats

    Article • Endocrinology, March 2005, Endocrine Society

    Professor David A Morilak

  34. What should animal models of depression model?

    Article • Neuroscience & Biobehavioral Reviews, January 2005, Elsevier

    Professor David A Morilak

  35. Galanin-mediated anxiolytic effect in rat central amygdala is not a result of corelease from noradrenergic terminals

    Article • Synapse, January 2005, Wiley

    Professor David A Morilak

  36. P.2.16 Noradrenergic facilitation of shock-probe defensive burying in lateral septum

    Article • European Neuropsychopharmacology, January 2005, Elsevier

    Professor David A Morilak

  37. Norepinephrine Release in Medial Amygdala Facilitates Activation of the Hypothalamic‐Pituitary‐Adrenal Axis in Response to Acute Immobilisation Stress

    Article • Journal of Neuroendocrinology, January 2005, Wiley

    Professor David A Morilak

  38. Autoreceptor‐mediated inhibition of norepinephrine release in rat medial prefrontal cortex is maintained after chronic desipramine treatment

    Article • Journal of Neurochemistry, September 2004, Wiley

    Professor David A Morilak

  39. Antidepressants and brain monoaminergic systems: a dimensional approach to understanding their behavioural effects in depression and anxiety disorders

    Article • The International Journal of Neuropsychopharmacology, June 2004, Oxford University Press (OUP)

    Professor David A Morilak

  40. Regulation of the norepinephrine transporter by chronic administration of antidepressants

    Article • Biological Psychiatry, February 2004, Elsevier

    Professor David A Morilak

  41. Induction of FOS expression by acute immobilization stress is reduced in locus coeruleus and medial amygdala of Wistar–Kyoto rats compared to Sprague–Dawley rats

    Article • Neuroscience, January 2004, Elsevier

    Professor David A Morilak

  42. Interactions of norepinephrine and galanin in the central amygdala and lateral bed nucleus of the stria terminalis modulate the behavioral response to acute stress

    Article • Life Sciences, June 2003, Elsevier

    Professor David A Morilak

  43. Regulatory Effects of Reboxetine Treatment Alone, or Following Paroxetine Treatment, on Brain Noradrenergic and Serotonergic Systems

    Article • Neuropsychopharmacology, May 2003, Springer Science + Business Media

    Professor David A Morilak

  44. Chronic cold stress sensitizes brain noradrenergic reactivity and noradrenergic facilitation of the HPA stress response in Wistar Kyoto rats

    Article • Brain Research, May 2003, Elsevier

    Professor David A Morilak

  45. New Developments in the Regulation of Monoaminergic Neurotransmission

    Article • March 2003, Taylor & Francis

    Professor David A Morilak

  46. Modulatory effects of norepinephrine, acting on alpha1 receptors in the central nucleus of the amygdala, on behavioral and neuroendocrine responses to acute immobilization stress

    Article • Neuropharmacology, December 2002, Elsevier

    Professor David A Morilak

  47. Stress reactivity of the brain noradrenergic system in three rat strains differing in their neuroendocrine and behavioral responses to stress: implications for susceptibility to stress-related neuropsychiatric disorders

    Article • Neuroscience, November 2002, Elsevier

    Professor David A Morilak

  48. Modulatory effects of norepinephrine in the lateral bed nucleus of the stria terminalis on behavioral and neuroendocrine responses to acute stress

    Article • Neuroscience, June 2002, Elsevier

    Professor David A Morilak

  49. Behavioral reactivity to stress

    Article • Pharmacology Biochemistry and Behavior, March 2002, Elsevier

    Professor David A Morilak

  50. Effects of acute restraint stress on tyrosine hydroxylase mRNA expression in locus coeruleus of Wistar and Wistar-Kyoto rats

    Article • Molecular Brain Research, January 2000, Elsevier

    Professor David A Morilak

  51. Expression of α1D adrenergic receptor messenger RNA in oxytocin- and corticotropin-releasing hormone-synthesizing neurons in the rat paraventricular nucleus

    Article • Neuroscience, June 1999, Elsevier

    Professor David A Morilak

  52. Reduced Noradrenergic Tone to the Hypothalamic Paraventricular Nucleus Contributes to the Stress Hyporesponsiveness of Lactation

    Article • Journal of Neuroendocrinology, June 1998, Wiley

    Professor David A Morilak

  53. Distribution of ?1A adrenergic receptor m RNA in the rat brain visualized by in situ hybridization

    Article • The Journal of Comparative Neurology, September 1997, Wiley

    Professor David A Morilak

  54. Co‐localization of α1D Adrenergic Receptor mRNA withMineralocorticoid and Glucocorticoid ReceptormRNA in Rat Hippocampus

    Article • Journal of Neuroendocrinology, February 1997, Wiley

    Professor David A Morilak

  55. α 1B adrenoceptors in rat paraventricular nucleus overlap with, but do not mediate, the induction of c-Fos expression by osmotic or restraint stress

    Article • Neuroscience, December 1996, Elsevier

    Professor David A Morilak

  56. Central adrenergic receptors and the HPA axis: Substrates for modulatory effects of stress?

    Article • European Neuropsychopharmacology, June 1996, Elsevier

    Professor David A Morilak

  57. Neurons Expressing 5-HT2 Receptors in the Rat Brain: Neurochemical Identification of Cell Types by Immunocytochemistry

    Article • Neuropsychopharmacology, November 1994, Springer Science + Business Media

    Professor David A Morilak

  58. 5-HT2 receptor immunoreactivity on cholinergic neurons of the pontomesencephalic tegmentum shown by double immunofluorescence

    Article • Brain Research, November 1993, Elsevier

    Professor David A Morilak

  59. Ontogeny of 5-hydroxytryptamine2 receptor immunoreactivity in the developing rat brain

    Article • Neuroscience, August 1993, Elsevier

    Professor David A Morilak

  60. Production and characterization of a specific 5-HT2 receptor antibody

    Article • Brain Research, June 1993, Elsevier

    Professor David A Morilak

  61. Immunocytochemical localization and description of neurons expressing serotonin2 receptors in the rat brain

    Article • Neuroscience, June 1993, Elsevier

    Professor David A Morilak

  62. Developmental Regulation of 5-HT2 and 5-HT1c Receptor Gene Expression in Rat Brain

    Article • January 1993, Springer Science + Business Media

    Professor David A Morilak

  63. Ontogeny of 5HT2 receptor gene expression in developing rat brain

    Article • European Neuropsychopharmacology, September 1992, Elsevier

    Professor David A Morilak

  64. Endogenous opioids tonically inhibit the depressor neurones in the caudal ventrolateral medulla of rabbits: Mediation through δ- and ϰ-receptors

    Article • Neuropharmacology, April 1991, Elsevier

    Professor David A Morilak

  65. Afferent Inputs to Ventrolateral Medulla

    Article • January 1991, Springer Science + Business Media

    Professor David A Morilak

  66. Opioid innervation of the caudal ventrolateral medulla is not critical for the expression of the aortic depressor nerve response in the rabbit

    Article • Journal of the Autonomic Nervous System, January 1991, Elsevier

    Professor David A Morilak

  67. Single-unit and physiological analyses of brain norepinephrine function in behaving animals

    Article • January 1991, Elsevier

    Professor David A Morilak

  68. A LACK OF POTENCY FOR THE δ‐OPIOID ANTAGONIST NALTRINDOLE AFTER MICROINJECTION INTO THE ROSTRAL VENTROLATERAL MEDULLA OF RABBITS

    Article • Clinical and Experimental Pharmacology and Physiology, July 1990, Wiley

    Professor David A Morilak

  69. Neuropeptide Y-immunoreactive synapses in the intermediolateral cell column of rat and rabbit thoracic spinal cord

    Article • Neuroscience Letters, January 1990, Elsevier

    Professor David A Morilak

  70. Evidence for an excitatory amino acid pathway in the brainstem and for its involvement in cardiovascular control

    Article • Brain Research, September 1989, Elsevier

    Professor David A Morilak

  71. An enkephalin-containing pathway from nucleus tractus solitarius to the pressor area of the rostral ventrolateral medulla of the rabbit

    Article • Neuroscience, January 1989, Elsevier

    Professor David A Morilak

  72. Release of substance P in the nucleus tractus solitarius measured by in vivo microdialysis: response to stimulation of the aortic depressor nerves in rabbit

    Article • Neuroscience Letters, November 1988, Elsevier

    Professor David A Morilak

  73. Single-unit responses of serotonergic dorsal raphe nucleus neurons to environmental heating and pyrogen administration in freely moving cats

    Article • Experimental Neurology, November 1987, Elsevier

    Professor David A Morilak

  74. Effects of physiological manipulations on locus coeruleus neuronal activity in freely moving cats. I. Thermoregulatory challenge

    Article • Brain Research, September 1987, Elsevier

    Professor David A Morilak

  75. Effects of physiological manipulations on locus coeruleus neuronal activity in freely moving cats. II. Cardiovascular challenge

    Article • Brain Research, September 1987, Elsevier

    Professor David A Morilak

  76. Effects of physiological manipulations on locus coeruleus neuronal activity in freely moving cats. III. Glucoregulatory challenge

    Article • Brain Research, September 1987, Elsevier

    Professor David A Morilak

  77. Single unit activity of noradrenergic neurons in locus coeruleus and serotonergic neurons in the nucleus raphe dorsalis of freely moving cats in relation to the cardiac cycle

    Article • Brain Research, December 1986, Elsevier

    Professor David A Morilak

  78. Single unit activity of locus coeruleus neurons in the freely moving cat

    Article • Brain Research, April 1986, Elsevier

    Professor David A Morilak

  79. Persistence of flavor neophobia as an indicator of state-dependent retention induced by pentobarbital, stress, and estrus

    Article • Behavioral and Neural Biology, May 1983, Elsevier

    Professor David A Morilak

  80. Anterograde memory loss induced by hypothermia in rats

    Article • Behavioral and Neural Biology, January 1983, Elsevier

    Professor David A Morilak