All Stories

  1. Correction: D’Amico et al. Toxic Exposure to Endocrine Disruptors Worsens Parkinson’s Disease Progression through NRF2/HO-1 Alteration. Biomedicines 2022, 10, 1073

    Article • Biomedicines, April 2024, MDPI AG

    Salvatore Cuzzocrea

  2. Sensory Properties, Redox Characteristics, and Impact on the Hemodynamics of the Flavanol-Rich Fraction Originated Grape and Blueberry

    Article • March 2024, MDPI AG

    Salvatore Cuzzocrea

  3. Correction: Casili et al. Therapeutic Potential of BAY-117082, a Selective NLRP3 Inflammasome Inhibitor, on Metastatic Evolution in Human Oral Squamous Cell Carcinoma (OSCC). Cancers 2023, 15, 2796

    Article • Cancers, March 2024, MDPI AG

    Salvatore Cuzzocrea

  4. Correction: D’Amico et al. Consumption of Cashew (Anacardium occidentale L.) Nuts Counteracts Oxidative Stress and Tissue Inflammation in Mild Hyperhomocysteinemia in Rats. Nutrients 2022, 14, 1474

    Article • Nutrients, December 2023, MDPI AG

    Salvatore Cuzzocrea

  5. To Go Where Nature Leads: Focus on Palmitoylethanolamide and Related ALIAmides as Innovative Approach to Neuroinflammatory and Pain-Related Disease States in Honor of Doctor Francesco Della Valle

    Article • Biomolecules, October 2023, MDPI AG

    Salvatore Cuzzocrea

  6. Interleukin-21 Influences Glioblastoma Course: Biological Mechanisms and Therapeutic Potential

    Article • Cells, September 2023, MDPI AG

    Salvatore Cuzzocrea

  7. What Is the Role of Palmitoylethanolamide Co-Ultramicronized with Luteolin on the Symptomatology Reported by Patients Suffering from Long COVID? A Retrospective Analysis Performed by a Group of General Practitioners in a Real-Life Setting

    Article • Nutrients, August 2023, MDPI AG

    Prof. Maurizio Evangelista, Salvatore Cuzzocrea

  8. Efficacy of Palmitoylethanolamide and Luteolin Association on Post-Covid Olfactory Dysfunction: A Systematic Review and Meta-Analysis of Clinical Studies

    Article • Biomedicines, August 2023, MDPI AG

    Salvatore Cuzzocrea

  9. Antioxidant Activity of a Sicilian Almond Skin Extract Using In Vitro and In Vivo Models

    Article • International Journal of Molecular Sciences, July 2023, MDPI AG

    Salvatore Cuzzocrea

  10. Modulation of TLR4/NFκB Pathways in Autoimmune Myocarditis

    Article • Antioxidants, July 2023, MDPI AG

    Salvatore Cuzzocrea

  11. Modulation of the Proliferative Pathway, Neuroinflammation and Pain in Endometriosis

    Article • International Journal of Molecular Sciences, July 2023, MDPI AG

    Salvatore Cuzzocrea

  12. Current Review of Increasing Animal Health Threat of Per- and Polyfluoroalkyl Substances (PFAS): Harms, Limitations, and Alternatives to Manage Their Toxicity

    Article • International Journal of Molecular Sciences, July 2023, MDPI AG

    Salvatore Cuzzocrea

  13. Aggravation of TGFβ1-Smad Pathway and Autoimmune Myocarditis by Fungicide (Tebuconazole) Exposure

    Article • International Journal of Molecular Sciences, July 2023, MDPI AG

    Salvatore Cuzzocrea

  14. Targeting Nrf2 and NF-κB Signaling Pathways in Inflammatory Pain: The Role of Polyphenols from Thinned Apples

    Article • Molecules, July 2023, MDPI AG

    Salvatore Cuzzocrea

  15. An RNAi-Mediated Reduction in Transcription Factor Nrf-2 Blocks the Positive Effects of Dimethyl Fumarate on Metabolic Stress in Alzheimer’s Disease

    Article • International Journal of Molecular Sciences, July 2023, MDPI AG

    Salvatore Cuzzocrea

  16. Toxic Effects of Gemcitabine and Paclitaxel Combination: Chemotherapy Drugs Exposure in Zebrafish

    Article • Toxics, June 2023, MDPI AG

    Salvatore Cuzzocrea

  17. Inhibition of Fatty Acid Amide Hydrolase (FAAH) Regulates NF-kb Pathways Reducing Bleomycin-Induced Chronic Lung Inflammation and Pulmonary Fibrosis

    Article • International Journal of Molecular Sciences, June 2023, MDPI AG

    Salvatore Cuzzocrea

  18. Baicalein Extract from Chinese Herbal Medicine to Use in Cardiovascular Diseases

    Article • June 2023, Taylor & Francis

    Salvatore Cuzzocrea

  19. The Transcription Factor Nrf2 Mediates the Effects of Antrodia camphorata Extract on Neuropathological Changes in a Mouse Model of Parkinson’s Disease

    Article • International Journal of Molecular Sciences, May 2023, MDPI AG

    Salvatore Cuzzocrea

  20. Effect of Pesticide Vinclozolin Toxicity Exposure on Cardiac Oxidative Stress and Myocardial Damage

    Article • Toxics, May 2023, MDPI AG

    Salvatore Cuzzocrea

  21. Therapeutic Potential of BAY-117082, a Selective NLRP3 Inflammasome Inhibitor, on Metastatic Evolution in Human Oral Squamous Cell Carcinoma (OSCC)

    Article • Cancers, May 2023, MDPI AG

    Salvatore Cuzzocrea

  22. Redox Imbalance in Neurological Disorders in Adults and Children

    Article • Antioxidants, April 2023, MDPI AG

    Salvatore Cuzzocrea

  23. Bioactive Compounds of the Mediterranean Diet as Nutritional Support to Fight Neurodegenerative Disease

    Article • International Journal of Molecular Sciences, April 2023, MDPI AG

    Salvatore Cuzzocrea

  24. MemophenolTM Prevents Amyloid-β Deposition and Attenuates Inflammation and Oxidative Stress in the Brain of an Alzheimer’s Disease Rat

    Article • International Journal of Molecular Sciences, April 2023, MDPI AG

    Salvatore Cuzzocrea

  25. Correction: Antonuccio et al. The Nutraceutical N-Palmitoylethanolamide (PEA) Reveals Widespread Molecular Effects Unmasking New Therapeutic Targets in Murine Varicocele. Nutrients 2021, 13, 734

    Article • Nutrients, March 2023, MDPI AG

    Salvatore Cuzzocrea

  26. Inhibition of LRRK2 Attenuates Depression-Related Symptoms in Mice with Moderate Traumatic Brain Injury

    Article • Cells, March 2023, MDPI AG

    Salvatore Cuzzocrea

  27. Role of Basic Fibroblast Growth Factor in Cancer: Biological Activity, Targeted Therapies, and Prognostic Value

    Article • Cells, March 2023, MDPI AG

    Salvatore Cuzzocrea

  28. The Role of miR-128 in Neurodegenerative Diseases

    Article • International Journal of Molecular Sciences, March 2023, MDPI AG

    Salvatore Cuzzocrea

  29. Endocrine Disruptor Compounds in Environment: Focus on Women’s Reproductive Health and Endometriosis

    Article • International Journal of Molecular Sciences, March 2023, MDPI AG

    Salvatore Cuzzocrea

  30. Recent Emerging Immunological Treatments for Primary Brain Tumors: Focus on Chemokine-Targeting Immunotherapies

    Article • Cells, March 2023, MDPI AG

    Salvatore Cuzzocrea

  31. Fisetin, a Natural Polyphenol, Ameliorates Endometriosis Modulating Mast Cells Derived NLRP-3 Inflammasome Pathway and Oxidative Stress

    Article • International Journal of Molecular Sciences, March 2023, MDPI AG

    Salvatore Cuzzocrea

  32. Molecular Investigation of DKK3 in Cerebral Ischemic/Reperfusion Injury

    Article • Biomedicines, March 2023, MDPI AG

    Salvatore Cuzzocrea

  33. Analysis of the Influence of IL-6 and the Activation of the Jak/Stat3 Pathway in Fibromyalgia

    Article • Biomedicines, March 2023, MDPI AG

    Salvatore Cuzzocrea

  34. Mechanism of Action of Natural Compounds in Peripheral Multiorgan Dysfunction and Hippocampal Neuroinflammation Induced by Sepsis

    Article • Antioxidants, March 2023, MDPI AG

    Salvatore Cuzzocrea

  35. Cytoprotective and Antioxidant Effects of Hydrolysates from Black Soldier Fly (Hermetia illucens)

    Article • Antioxidants, February 2023, MDPI AG

    Salvatore Cuzzocrea

  36. Evaluation of the Efficacy of Xyloglucan, Pea Protein and Opuntia ficus-indica Extract in a Preclinical Model of Psoriasis

    Article • International Journal of Molecular Sciences, February 2023, MDPI AG

    Salvatore Cuzzocrea

  37. Hydroxytyrosol and Its Potential Uses on Intestinal and Gastrointestinal Disease

    Article • International Journal of Molecular Sciences, February 2023, MDPI AG

    Salvatore Cuzzocrea

  38. Therapeutic Potential of Dimethyl Fumarate in Counteract Oral Squamous Cell Carcinoma Progression by Modulating Apoptosis, Oxidative Stress and Epithelial–Mesenchymal Transition

    Article • International Journal of Molecular Sciences, February 2023, MDPI AG

    Salvatore Cuzzocrea

  39. Açai Berry Administration Promotes Wound Healing through Wnt/β-Catenin Pathway

    Article • International Journal of Molecular Sciences, January 2023, MDPI AG

    Salvatore Cuzzocrea

  40. Oxygen Sensing in Neurodegenerative Diseases: Current Mechanisms, Implication of Transcriptional Response, and Pharmacological Modulation

    Article • Antioxidants & Redox Signaling, January 2023, Mary Ann Liebert Inc

    Salvatore Cuzzocrea

  41. Actaea racemosa L. Rhizome Protect against MPTP-Induced Neurotoxicity in Mice by Modulating Oxidative Stress and Neuroinflammation

    Article • Antioxidants, December 2022, MDPI AG

    Salvatore Cuzzocrea

  42. Complex Interplay between Autophagy and Oxidative Stress in the Development of Endometriosis

    Article • Antioxidants, December 2022, MDPI AG

    Salvatore Cuzzocrea

  43. The Pivotal Role of Protein Phosphatase 2A (PP2A) in Brain Tumors

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Salvatore Cuzzocrea

  44. Protein Kinase Inhibitors as a New Target for Immune System Modulation and Brain Cancer Management

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Salvatore Cuzzocrea

  45. Early Exposure to Environmental Pollutants: Imidacloprid Potentiates Cadmium Toxicity on Zebrafish Retinal Cells Death

    Article • Animals, December 2022, MDPI AG

    Salvatore Cuzzocrea

  46. Regulation of Apoptosis and Oxidative Stress by Oral Boswellia Serrata Gum Resin Extract in a Rat Model of Endometriosis

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Salvatore Cuzzocrea

  47. A Combination of Xyloglucan, Pea Protein and Chia Seed Ameliorates Intestinal Barrier Integrity and Mucosa Functionality in a Rat Model of Constipation-Predominant Irritable Bowel Syndrome

    Article • Journal of Clinical Medicine, November 2022, MDPI AG

    Salvatore Cuzzocrea

  48. Açai Berry Attenuates Cyclophosphamide-Induced Damage in Genitourinary Axis-Modulating Nrf-2/HO-1 Pathways

    Article • Antioxidants, November 2022, MDPI AG

    Salvatore Cuzzocrea

  49. Intratesticular Versus Intrafunicular Lidocaine to Reduce Perioperative Nociception and Immunological Response in Ponies Undergoing Field Castration

    Article • Veterinary Sciences, November 2022, MDPI AG

    Salvatore Cuzzocrea

  50. Overview on Common Genes Involved in the Onset of Glioma and on the Role of Migraine as Risk Factor: Predictive Biomarkers or Therapeutic Targets?

    Article • Journal of Personalized Medicine, November 2022, MDPI AG

    Salvatore Cuzzocrea

  51. Modulation of NRF-2 Pathway Contributes to the Therapeutic Effects of Boswellia serrata Gum Resin Extract in a Model of Experimental Autoimmune Myocarditis

    Article • Antioxidants, October 2022, MDPI AG

    Salvatore Cuzzocrea

  52. Natural Compounds such as Hericium erinaceus and Coriolus versicolor Modulate Neuroinflammation, Oxidative Stress and Lipoxin A4 Expression in Rotenone-Induced Parkinson’s Disease in Mice

    Article • Biomedicines, October 2022, MDPI AG

    Salvatore Cuzzocrea

  53. Chronic Exposure to Endocrine Disruptor Vinclozolin Leads to Lung Damage Via Nrf2–Nf-kb Pathway Alterations

    Article • International Journal of Molecular Sciences, September 2022, MDPI AG

    Salvatore Cuzzocrea

  54. Chronic Exposure to Vinclozolin Induced Fibrosis, Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Mice Kidney

    Article • International Journal of Molecular Sciences, September 2022, MDPI AG

    Salvatore Cuzzocrea

  55. Trehalose–Carnosine Prevents the Effects of Spinal Cord Injury Through Regulating Acute Inflammation and Zinc(II) Ion Homeostasis

    Article • Cellular and Molecular Neurobiology, September 2022, Springer Science + Business Media

    Salvatore Cuzzocrea

  56. Aerosol-Administered Adelmidrol Attenuates Lung Inflammation in a Murine Model of Acute Lung Injury

    Article • Biomolecules, September 2022, MDPI AG

    Salvatore Cuzzocrea

  57. Dimethyl Fumarate (DMF) Alleviated Post-Operative (PO) Pain through the N-Methyl-d-Aspartate (NMDA) Receptors

    Article • Antioxidants, September 2022, MDPI AG

    Salvatore Cuzzocrea

  58. Açai Berry Mitigates Vascular Dementia-Induced Neuropathological Alterations Modulating Nrf-2/Beclin1 Pathways

    Article • Cells, August 2022, MDPI AG

    Salvatore Cuzzocrea

  59. Adenosine Targeting as a New Strategy to Decrease Glioblastoma Aggressiveness

    Article • Cancers, August 2022, MDPI AG

    Salvatore Cuzzocrea

  60. Impact of Mycotoxin Contaminations on Aquatic Organisms: Toxic Effect of Aflatoxin B1 and Fumonisin B1 Mixture

    Article • Toxins, July 2022, MDPI AG

    Salvatore Cuzzocrea

  61. Snail Mucus Filtrate Reduces Inflammation in Canine Progenitor Epidermal Keratinocytes (CPEK)

    Article • Animals, July 2022, MDPI AG

    Salvatore Cuzzocrea

  62. Environmental Impact of Pharmaceutical Pollutants: Synergistic Toxicity of Ivermectin and Cypermethrin

    Article • Toxics, July 2022, MDPI AG

    Salvatore Cuzzocrea

  63. Discovering the Effects of Fisetin on NF-κB/NLRP-3/NRF-2 Molecular Pathways in a Mouse Model of Vascular Dementia Induced by Repeated Bilateral Carotid Occlusion

    Article • Biomedicines, June 2022, MDPI AG

    Salvatore Cuzzocrea

  64. Role of Etanercept and Infliximab on Nociceptive Changes Induced by the Experimental Model of Fibromyalgia

    Article • International Journal of Molecular Sciences, May 2022, MDPI AG

    Salvatore Cuzzocrea

  65. Efficacy of a Novel Therapeutic, Based on Natural Ingredients and Probiotics, in a Murine Model of Multiple Food Intolerance and Maldigestion

    Article • Nutrients, May 2022, MDPI AG

    Salvatore Cuzzocrea

  66. Environmental Risk Assessment of Dexamethasone Sodium Phosphate and Tocilizumab Mixture in Zebrafish Early Life Stage (Danio rerio)

    Article • Toxics, May 2022, MDPI AG

    Salvatore Cuzzocrea

  67. Environmental Toxicity Assessment of Sodium Fluoride and Platinum-Derived Drugs Co-Exposure on Aquatic Organisms

    Article • Toxics, May 2022, MDPI AG

    Salvatore Cuzzocrea

  68. Toxic Exposure to Endocrine Disruptors Worsens Parkinson’s Disease Progression through NRF2/HO-1 Alteration

    Article • Biomedicines, May 2022, MDPI AG

    Salvatore Cuzzocrea

  69. Supplementation with SCFAs Re-Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG-Induced Migraine

    Article • International Journal of Molecular Sciences, April 2022, MDPI AG

    Salvatore Cuzzocrea

  70. Evaluation of a Gel Containing a Propionibacterium Extract in an In Vivo Model of Wound Healing

    Article • International Journal of Molecular Sciences, April 2022, MDPI AG

    Salvatore Cuzzocrea

  71. Combined Effects of Potassium Perchlorate and a Neonicotinoid on Zebrafish Larvae (Danio rerio)

    Article • Toxics, April 2022, MDPI AG

    Salvatore Cuzzocrea

  72. Environmental Co-Exposure to Potassium Perchlorate and Cd Caused Toxicity and Thyroid Endocrine Disruption in Zebrafish Embryos and Larvae (Danio rerio)

    Article • Toxics, April 2022, MDPI AG

    Salvatore Cuzzocrea

  73. S-Acetyl-Glutathione Attenuates Carbon Tetrachloride-Induced Liver Injury by Modulating Oxidative Imbalance and Inflammation

    Article • International Journal of Molecular Sciences, April 2022, MDPI AG

    Salvatore Cuzzocrea

  74. Toxic Effects of Endocrine Disruptor Exposure on Collagen-Induced Arthritis

    Article • Biomolecules, April 2022, MDPI AG

    Salvatore Cuzzocrea

  75. Role of Bevacizumab on Vascular Endothelial Growth Factor in Apolipoprotein E Deficient Mice after Traumatic Brain Injury

    Article • International Journal of Molecular Sciences, April 2022, MDPI AG

    Salvatore Cuzzocrea

  76. Resveratrol Inhibition of the WNT/β-Catenin Pathway following Discogenic Low Back Pain

    Article • International Journal of Molecular Sciences, April 2022, MDPI AG

    Salvatore Cuzzocrea

  77. Consumption of Cashew (Anacardium occidentale L.) Nuts Counteracts Oxidative Stress and Tissue Inflammation in Mild Hyperhomocysteinemia in Rats

    Article • Nutrients, April 2022, MDPI AG

    Salvatore Cuzzocrea

  78. Sensitivity of Zebrafish Embryogenesis to Risk of Fotemustine Exposure

    Article • Fishes, March 2022, MDPI AG

    Salvatore Cuzzocrea

  79. Fatty Acid Amide Hydrolase (FAAH) Inhibition Plays a Key Role in Counteracting Acute Lung Injury

    Article • International Journal of Molecular Sciences, March 2022, MDPI AG

    Salvatore Cuzzocrea

  80. The Biological Function of MicroRNAs in Bone Tumors

    Article • International Journal of Molecular Sciences, February 2022, MDPI AG

    Salvatore Cuzzocrea

  81. Efficacy of a Product Containing Xyloglucan and Pea Protein on Intestinal Barrier Function in a Partial Restraint Stress Animal Model

    Article • International Journal of Molecular Sciences, February 2022, MDPI AG

    Salvatore Cuzzocrea

  82. Coriolus Versicolor Downregulates TLR4/NF-κB Signaling Cascade in Dinitrobenzenesulfonic Acid-Treated Mice: A Possible Mechanism for the Anti-Colitis Effect

    Article • Antioxidants, February 2022, MDPI AG

    Salvatore Cuzzocrea

  83. Environmental Risk Assessment of Oxaliplatin Exposure on Early Life Stages of Zebrafish (Danio rerio)

    Article • Toxics, February 2022, MDPI AG

    Salvatore Cuzzocrea

  84. Evaluation of Betacoronavirus OC43 and SARS-CoV-2 Elimination by Zefero Air Sanitizer Device in a Novel Laboratory Recirculation System

    Article • Pathogens, February 2022, MDPI AG

    Salvatore Cuzzocrea

  85. Role of EPA in Inflammation: Mechanisms, Effects, and Clinical Relevance

    Article • Biomolecules, February 2022, MDPI AG

    Salvatore Cuzzocrea

  86. Assessment of 2-Pentadecyl-2-oxazoline Role on Lipopolysaccharide-Induced Inflammation on Early Stage Development of Zebrafish (Danio rerio)

    Article • Life, January 2022, MDPI AG

    Salvatore Cuzzocrea

  87. Intestinal Disorder in Zebrafish Larvae (Danio rerio): The Protective Action of N-Palmitoylethanolamide-oxazoline

    Article • Life, January 2022, MDPI AG

    Salvatore Cuzzocrea

  88. Mineral Composition in Delactosed Dairy Products: Quality and Safety Status

    Article • Foods, January 2022, MDPI AG

    Salvatore Cuzzocrea

  89. Combined Toxicity of Xenobiotics Bisphenol A and Heavy Metals on Zebrafish Embryos (Danio rerio)

    Article • Toxics, December 2021, MDPI AG

    Salvatore Cuzzocrea

  90. Wnt/β-Catenin Pathway in Experimental Model of Fibromyalgia: Role of Hidrox®

    Article • Biomedicines, November 2021, MDPI AG

    Salvatore Cuzzocrea

  91. Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer’s Disease

    Article • Antioxidants, October 2021, MDPI AG

    Salvatore Cuzzocrea

  92. Ultramicronized Palmitoylethanolamide in the Management of Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation

    Article • International Journal of Molecular Sciences, October 2021, MDPI AG

    Salvatore Cuzzocrea

  93. Aflatoxin B1 Toxicity in Zebrafish Larva (Danio rerio): Protective Role of Hericium erinaceus

    Article • Toxins, October 2021, MDPI AG

    Salvatore Cuzzocrea

  94. Evaluating the Protective Properties of a Xyloglucan-Based Nasal Spray in a Mouse Model of Allergic Rhinitis

    Article • International Journal of Molecular Sciences, September 2021, MDPI AG

    Salvatore Cuzzocrea

  95. Micro Composite Palmitoylethanolamide/Rutin Reduces Vascular Injury through Modulation of the Nrf2/HO−1 and NF-kB Pathways

    Article • Current Medicinal Chemistry, September 2021, Bentham Science Publishers

    Salvatore Cuzzocrea

  96. Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood

    Article • Veterinary Sciences, September 2021, MDPI AG

    Salvatore Cuzzocrea

  97. The Protective Effect of Snail Secretion Filtrate in an Experimental Model of Excisional Wounds in Mice

    Article • Veterinary Sciences, August 2021, MDPI AG

    Salvatore Cuzzocrea

  98. Co-Ultra PEALut Enhances Endogenous Repair Response Following Moderate Traumatic Brain Injury

    Article • International Journal of Molecular Sciences, August 2021, MDPI AG

    Salvatore Cuzzocrea

  99. Atrazine Inhalation Causes Neuroinflammation, Apoptosis and Accelerating Brain Aging

    Article • International Journal of Molecular Sciences, July 2021, MDPI AG

    Salvatore Cuzzocrea

  100. KYP-2047, an Inhibitor of Prolyl-Oligopeptidase, Reduces GlioBlastoma Proliferation through Angiogenesis and Apoptosis Modulation

    Article • Cancers, July 2021, MDPI AG

    Salvatore Cuzzocrea

  101. Poly (ADP-Ribose) Polymerase Inhibitor, ABT888, Improved Cisplatin Effect in Human Oral Cell Carcinoma

    Article • Biomedicines, July 2021, MDPI AG

    Salvatore Cuzzocrea

  102. Hidrox ® and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain

    Article • Antioxidants, June 2021, MDPI AG

    Salvatore Cuzzocrea

  103. Epigallocatechin-3-Gallate Modulates Postoperative Pain by Regulating Biochemical and Molecular Pathways

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Salvatore Cuzzocrea

  104. Palmitoylethanolamide/Baicalein Regulates the Androgen Receptor Signaling and NF-κB/Nrf2 Pathways in Benign Prostatic Hyperplasia

    Article • Antioxidants, June 2021, MDPI AG

    Salvatore Cuzzocrea

  105. Inhibition of P2X7 Purinergic Receptor Ameliorates Fibromyalgia Syndrome by Suppressing NLRP3 Pathway

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Salvatore Cuzzocrea

  106. Hericium erinaceus and Coriolus versicolor Modulate Molecular and Biochemical Changes after Traumatic Brain Injury

    Article • Antioxidants, June 2021, MDPI AG

    Salvatore Cuzzocrea

  107. Regulation of Inflammatory and Proliferative Pathways by Fotemustine and Dexamethasone in Endometriosis

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Salvatore Cuzzocrea

  108. Management of Acute Lung Injury: Palmitoylethanolamide as a New Approach

    Article • International Journal of Molecular Sciences, May 2021, MDPI AG

    Salvatore Cuzzocrea

  109. Hidrox® Roles in Neuroprotection: Biochemical Links between Traumatic Brain Injury and Alzheimer’s Disease

    Article • Antioxidants, May 2021, MDPI AG

    Salvatore Cuzzocrea

  110. Hidrox® Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model

    Article • Antioxidants, May 2021, MDPI AG

    Salvatore Cuzzocrea

  111. Autophagy and Mitophagy Promotion in a Rat Model of Endometriosis

    Article • International Journal of Molecular Sciences, May 2021, MDPI AG

    Salvatore Cuzzocrea

  112. Hidrox® and Endometriosis: Biochemical Evaluation of Oxidative Stress and Pain

    Article • Antioxidants, May 2021, MDPI AG

    Salvatore Cuzzocrea

  113. Role of miRNA-19a in Cancer Diagnosis and Poor Prognosis

    Article • International Journal of Molecular Sciences, April 2021, MDPI AG

    Salvatore Cuzzocrea

  114. The Methyl Ester of 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid Reduces Endometrial Lesions Development by Modulating the NFkB and Nrf2 Pathways

    Article • International Journal of Molecular Sciences, April 2021, MDPI AG

    Salvatore Cuzzocrea

  115. PEA-OXA Mitigates Oxaliplatin-Induced Painful Neuropathy through NF-κB/Nrf-2 Axis

    Article • International Journal of Molecular Sciences, April 2021, MDPI AG

    Salvatore Cuzzocrea

  116. Fibromyalgia: Pathogenesis, Mechanisms, Diagnosis and Treatment Options Update

    Article • International Journal of Molecular Sciences, April 2021, MDPI AG

    Salvatore Cuzzocrea

  117. Immunomodulatory Effect of Microglia-Released Cytokines in Gliomas

    Article • Brain Sciences, April 2021, MDPI AG

    Salvatore Cuzzocrea

  118. PEA/Polydatin: Anti-Inflammatory and Antioxidant Approach to Counteract DNBS-Induced Colitis

    Article • Antioxidants, March 2021, MDPI AG

    Salvatore Cuzzocrea

  119. The Nutraceutical N-Palmitoylethanolamide (PEA) Reveals Widespread Molecular Effects Unmasking New Therapeutic Targets in Murine Varicocele

    Article • Nutrients, February 2021, MDPI AG

    Salvatore Cuzzocrea

  120. Effect of Ultra-Micronized-Palmitoylethanolamide and Acetyl-l-Carnitine on Experimental Model of Inflammatory Pain

    Article • International Journal of Molecular Sciences, February 2021, MDPI AG

    Salvatore Cuzzocrea

  121. Plumericin Protects against Experimental Inflammatory Bowel Disease by Restoring Intestinal Barrier Function and Reducing Apoptosis

    Article • Biomedicines, January 2021, MDPI AG

    Salvatore Cuzzocrea

  122. Involvements of Hyperhomocysteinemia in Neurological Disorders

    Article • Metabolites, January 2021, MDPI AG

    Salvatore Cuzzocrea

  123. TAK1 Inhibitor Enhances the Therapeutic Treatment for Glioblastoma

    Article • Cancers, December 2020, MDPI AG

    Salvatore Cuzzocrea

  124. Role of Fibroblast Growth Factors Receptors (FGFRs) in Brain Tumors, Focus on Astrocytoma and Glioblastoma

    Article • Cancers, December 2020, MDPI AG

    Salvatore Cuzzocrea

  125. TLR7/8 in the Pathogenesis of Parkinson’s Disease

    Article • International Journal of Molecular Sciences, December 2020, MDPI AG

    Salvatore Cuzzocrea

  126. Protective Effect of Silibinin on Lipopolysaccharide-Induced Inflammatory Responses in Equine Peripheral Blood Mononuclear Cells, an In Vitro Study

    Article • Animals, November 2020, MDPI AG

    Salvatore Cuzzocrea

  127. Protective effects of Colomast®, A New Formulation of Adelmidrol and Sodium Hyaluronate, in A Mouse Model of Acute Restraint Stress

    Article • International Journal of Molecular Sciences, October 2020, MDPI AG

    Salvatore Cuzzocrea

  128. Protective Effect of Hydroxytyrosol on LPS-Induced Inflammation and Oxidative Stress in Bovine Endometrial Epithelial Cell Line

    Article • Veterinary Sciences, October 2020, MDPI AG

    Salvatore Cuzzocrea

  129. Treatment with Luteolin Improves Lipopolysaccharide-Induced Periodontal Diseases in Rats

    Article • Biomedicines, October 2020, MDPI AG

    Salvatore Cuzzocrea

  130. Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Inhibitor as a Novel Therapeutic Tool for Lung Injury

    Article • International Journal of Molecular Sciences, October 2020, MDPI AG

    Salvatore Cuzzocrea

  131. The Protective Effects of Pre- and Post-Administration of Micronized Palmitoylethanolamide Formulation on Postoperative Pain in Rats

    Article • International Journal of Molecular Sciences, October 2020, MDPI AG

    Salvatore Cuzzocrea

  132. Cashew (Anacardium occidentale L.) Nuts Modulate the Nrf2 and NLRP3 Pathways in Pancreas and Lung after Induction of Acute Pancreatitis by Cerulein

    Article • Antioxidants, October 2020, MDPI AG

    Salvatore Cuzzocrea

  133. Synergic Therapeutic Potential of PEA-Um Treatment and NAAA Enzyme Silencing In the Management of Neuroinflammation

    Article • International Journal of Molecular Sciences, October 2020, MDPI AG

    Salvatore Cuzzocrea

  134. Dietary Supplementation with Palmitoyl-Glucosamine Co-Micronized with Curcumin Relieves Osteoarthritis Pain and Benefits Joint Mobility

    Article • Animals, October 2020, MDPI AG

    Salvatore Cuzzocrea

  135. Novel Combination of COX-2 Inhibitor and Antioxidant Therapy for Modulating Oxidative Stress Associated with Intestinal Ischemic Reperfusion Injury and Endotoxemia

    Article • Antioxidants, September 2020, MDPI AG

    Salvatore Cuzzocrea

  136. Anti-inflammatory and Anti-oxidant Activity of Hidrox® in Rotenone-Induced Parkinson’s Disease in Mice

    Article • Antioxidants, September 2020, MDPI AG

    Salvatore Cuzzocrea

  137. Biochemical Evaluation of the Antioxidant Effects of Hydroxytyrosol on Pancreatitis-Associated Gut Injury

    Article • Antioxidants, August 2020, MDPI AG

    Salvatore Cuzzocrea

  138. Oral Supplementation with Ultramicronized Palmitoylethanolamide for Joint Disease and Lameness Management in Four Jumping Horses: A Case Report

    Article • Animals, August 2020, MDPI AG

    Salvatore Cuzzocrea

  139. Formyl Peptide Receptor 1 Signaling in Acute Inflammation and Neural Differentiation Induced by Traumatic Brain Injury

    Article • Biology, August 2020, MDPI AG

    Salvatore Cuzzocrea

  140. ALIAmides Update: Palmitoylethanolamide and Its Formulations on Management of Peripheral Neuropathic Pain

    Article • International Journal of Molecular Sciences, July 2020, MDPI AG

    Salvatore Cuzzocrea

  141. Cashew (Anacardium occidentale L.) Nuts Counteract Oxidative Stress and Inflammation in an Acute Experimental Model of Carrageenan-Induced Paw Edema

    Article • Antioxidants, July 2020, MDPI AG

    Salvatore Cuzzocrea

  142. Protective Effect of Epigallocatechin-3-Gallate (EGCG) in Diseases with Uncontrolled Immune Activation: Could Such a Scenario Be Helpful to Counteract COVID-19?

    Article • International Journal of Molecular Sciences, July 2020, MDPI AG

    Salvatore Cuzzocrea

  143. Topical Delivery of Curcumin by Choline-Calix[4]arene-Based Nanohydrogel Improves Its Therapeutic Effect on a Psoriasis Mouse Model

    Article • International Journal of Molecular Sciences, July 2020, MDPI AG

    Salvatore Cuzzocrea

  144. Adelmidrol: A New Promising Antioxidant and Anti-Inflammatory Therapeutic Tool in Pulmonary Fibrosis

    Article • Antioxidants, July 2020, MDPI AG

    Salvatore Cuzzocrea

  145. Palmitoylethanolamide and Related ALIAmides: Prohomeostatic Lipid Compounds for Animal Health and Wellbeing

    Article • Veterinary Sciences, June 2020, MDPI AG

    Salvatore Cuzzocrea

  146. Focus on the Role of NLRP3 Inflammasome in Diseases

    Article • International Journal of Molecular Sciences, June 2020, MDPI AG

    Salvatore Cuzzocrea

  147. Effect of a Product Containing Xyloglucan and Pea Protein on a Murine Model of Atopic Dermatitis

    Article • International Journal of Molecular Sciences, May 2020, MDPI AG

    Salvatore Cuzzocrea

  148. Ultramicronized Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat

    Article • International Journal of Molecular Sciences, May 2020, MDPI AG

    Salvatore Cuzzocrea

  149. The Role of Annexin A1 and Formyl Peptide Receptor 2/3 Signaling in Chronic Corticosterone-Induced Depression-Like behaviors and Impairment in Hippocampal-Dependent Memory

    Article • CNS & Neurological Disorders - Drug Targets, April 2020, Bentham Science Publishers

    Salvatore Cuzzocrea, Ramona D'Amico

  150. The Anti-Inflammatory and Antioxidant Effects of Sodium Propionate

    Article • International Journal of Molecular Sciences, April 2020, MDPI AG

    Salvatore Cuzzocrea

  151. Management of Traumatic Brain Injury: From Present to Future

    Article • Antioxidants, April 2020, MDPI AG

    Salvatore Cuzzocrea

  152. Modulation of NLRP3 Inflammasome through Formyl Peptide Receptor 1 (Fpr-1) Pathway as a New Therapeutic Target in Bronchiolitis Obliterans Syndrome

    Article • International Journal of Molecular Sciences, March 2020, MDPI AG

    Salvatore Cuzzocrea

  153. The Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale L. Cashew Nuts in a Mouse Model of Colitis

    Article • Nutrients, March 2020, MDPI AG

    Salvatore Cuzzocrea

  154. An Update of Palmitoylethanolamide and Luteolin Effects in Preclinical and Clinical Studies of Neuroinflammatory Events

    Article • Antioxidants, March 2020, MDPI AG

    Salvatore Cuzzocrea

  155. The Protective Effect of New Carnosine-Hyaluronic Acid Conjugate on the Inflammation and Cartilage Degradation in the Experimental Model of Osteoarthritis

    Article • Applied Sciences, February 2020, MDPI AG

    Salvatore Cuzzocrea

  156. N-acetyl-L-cysteine reduces Leishmania amazonensis-induced inflammation in BALB/c mice

    Article • BMC Veterinary Research, January 2020, Springer Science + Business Media

    Salvatore Cuzzocrea

  157. Protective Effect of New Formulation of Carnosine+Hyaluronic Acid on the Inflammation and Cartilage Degradation in the Experimental Model of Osteoarthritis

    Article • January 2020, MDPI AG

    Salvatore Cuzzocrea

  158. Co-ultraPEALut: Role in Preclinical and Clinical Delirium Manifestations

    Article • CNS & Neurological Disorders - Drug Targets, December 2019, Bentham Science Publishers

    Salvatore Cuzzocrea, maria lia lunardeli , Giorgio Cocuzza

  159. Melatonin Plus Folic Acid Treatment Ameliorates Reserpine-Induced Fibromyalgia: An Evaluation of Pain, Oxidative Stress, and Inflammation

    Article • Antioxidants, December 2019, MDPI AG

    Salvatore Cuzzocrea

  160. The neuroprotective effects of micronized PEA (PEA-m) formulation on diabetic peripheral neuropathy in mice

    Article • The FASEB Journal, October 2019, Federation of American Societies For Experimental Biology (FASEB)

    Salvatore Cuzzocrea

  161. N-Palmitoylethanolamide-Oxazoline Protects against Middle Cerebral Artery Occlusion Injury in Diabetic Rats by Regulating the SIRT1 Pathway

    Article • International Journal of Molecular Sciences, September 2019, MDPI AG

    Salvatore Cuzzocrea

  162. Therapeutic Efficacy of Palmitoylethanolamide and Its New Formulations in Synergy with Different Antioxidant Molecules Present in Diets

    Article • Nutrients, September 2019, MDPI AG

    Salvatore Cuzzocrea

  163. Interferon Alpha Has a Strong Anti-tumor Effect in Philadelphia-negative Myeloproliferative Neoplasms

    Article • Clinical Lymphoma Myeloma & Leukemia, August 2019, Elsevier

    Salvatore Cuzzocrea

  164. Susceptibility of erythrocytes from different sources to xenobiotics-induced lysis

    Article • Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, July 2019, Elsevier

    Salvatore Cuzzocrea

  165. N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion

    Article • Neurobiology of Disease, May 2019, Elsevier

    Salvatore Cuzzocrea

  166. A randomized, controlled, phase II clinical trial of β‐D‐mannuronic acid (M2000) in pre‐surgical breast cancer patients at early stage (T1‐T2)

    Article • Clinical and Experimental Pharmacology and Physiology, April 2019, Wiley

    Salvatore Cuzzocrea

  167. Neutrophil elastase plays a non‐redundant role in remodeling the venular basement membrane and neutrophil diapedesis post‐ischemia/reperfusion injury

    Article • The Journal of Pathology, March 2019, Wiley

    Salvatore Cuzzocrea

  168. Correction to “Potential Eye Drop Based on a Calix[4]arene Nanoassembly for Curcumin Delivery: Enhanced Drug Solubility, Stability, and Anti-Inflammatory Effect

    Article • Molecular Pharmaceutics, March 2019, American Chemical Society (ACS)

    Salvatore Cuzzocrea

  169. Role of Metabotropic Glutamate Receptors in Neurological Disorders

    Article • Frontiers in Molecular Neuroscience, February 2019, Frontiers

    Salvatore Cuzzocrea

  170. Involvement of TLR4 and PPAR-α Receptors in Host Response and NLRP3 Inflammasome Activation, Against Pulmonary Infection With Pseudomonas Aeruginosa

    Article • Shock, February 2019, Wolters Kluwer Health

    Salvatore Cuzzocrea

  171. Multidisciplinary approach to prostatitis

    Article • Archivio Italiano di Urologia e Andrologia, January 2019, PAGEPress Publications

    Salvatore Cuzzocrea

  172. The association of adelmidrol with sodium hyaluronate displays beneficial properties against bladder changes following spinal cord injury in mice

    Article • PLoS ONE, January 2019, PLOS

    Salvatore Cuzzocrea

  173. Treatment With a Flavonoid-Rich Fraction of Bergamot Juice Improved Lipopolysaccharide-Induced Periodontitis in Rats

    Article • Frontiers in Pharmacology, January 2019, Frontiers

    Salvatore Cuzzocrea

  174. International multicenter randomized, placebo-controlled phase III clinical trial of β-d-mannuronic acid in rheumatoid arthritis patients

    Article • Inflammopharmacology, January 2019, Springer Science + Business Media

    Seyed Shahabeddin Mortazavi-Jahromi, Salvatore Cuzzocrea

  175. Formyl peptide receptor 1 signalling promotes experimental colitis in mice

    Article • Pharmacological Research, January 2019, Elsevier

    Salvatore Cuzzocrea

  176. Pharmacodynamical effects of orally administered exenatide nanoparticles embedded in gastro-resistant microparticles

    Article • European Journal of Pharmaceutics and Biopharmaceutics, December 2018, Elsevier

    Salvatore Cuzzocrea

  177. Selective CB2 inverse agonist JTE907 drives T cell differentiation towards a Treg cell phenotype and ameliorates inflammation in a mouse model of inflammatory bowel disease

    Article • Pharmacological Research, December 2018, Elsevier

    Salvatore Cuzzocrea

  178. TLR4 absence reduces neuroinflammation and inflammasome activation in Parkinson’s diseases in vivo model

    Article • Brain Behavior and Immunity, December 2018, Elsevier

    Salvatore Cuzzocrea

  179. Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis

    Article • Journal of Medicinal Chemistry, October 2018, American Chemical Society (ACS)

    Salvatore Cuzzocrea

  180. AST-120 Reduces Neuroinflammation Induced by Indoxyl Sulfate in Glial Cells

    Article • Journal of Clinical Medicine, October 2018, MDPI AG

    Salvatore Cuzzocrea

  181. Effect of pea protein plus grape seed dry extract on a murine model of Candida albicans induced vaginitis

    Article • Future Microbiology, September 2018, Future Medicine

    Salvatore Cuzzocrea

  182. Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury

    Article • Molecular Neurobiology, September 2018, Springer Science + Business Media

    Salvatore Cuzzocrea

  183. Effect of PEA-OXA on neuropathic pain and functional recovery after sciatic nerve crush

    Article • Journal of Neuroinflammation, September 2018, Springer Science + Business Media

    Salvatore Cuzzocrea

  184. Effects of a new compound containing Palmitoylethanolamide and Baicalein in Myocardial Ischaemia/Reperfusion Injury in VIVO

    Article • Phytomedicine, September 2018, Elsevier

    Salvatore Cuzzocrea

  185. Therapeutic potential of dinitrobenzene sulfonic acid (DNBS)-induced colitis in mice by targeting IL-1β and IL-18

    Article • Biochemical Pharmacology, September 2018, Elsevier

    Salvatore Cuzzocrea

  186. Topical Application of Adelmidrol + Trans-Traumatic Acid Enhances Skin Wound Healing in a Streptozotocin-Induced Diabetic Mouse Model

    Article • Frontiers in Pharmacology, August 2018, Frontiers

    Salvatore Cuzzocrea

  187. Micronized palmitoylethanolamide reduces joint pain and glial cell activation

    Article • Inflammation Research, August 2018, Springer Science + Business Media

    Salvatore Cuzzocrea

  188. Laser-generated bismuth nanoparticles for applications in imaging and radiotherapy

    Article • Journal of Physics and Chemistry of Solids, August 2018, Elsevier

    Salvatore Cuzzocrea

  189. Adelmidrol + sodium hyaluronate in IC/BPS or conditions associated to chronic urothelial inflammation. A translational study

    Article • Pharmacological Research, August 2018, Elsevier

    Salvatore Cuzzocrea

  190. Correction: Effect of a new formulation of micronized and ultramicronized N-palmitoylethanolamine in a tibia fracture mouse model of complex regional pain syndrome

    Article • PLoS ONE, July 2018, PLOS

    Prof. Maurizio Evangelista, Salvatore Cuzzocrea

  191. Lung resident mesenchymal cells isolated from patients with the Bronchiolitis Obliterans Syndrome display a deregulated epigenetic profile

    Article • Scientific Reports, July 2018, Springer Science + Business Media

    Salvatore Cuzzocrea

  192. Absence of formyl peptide receptor 1 causes endometriotic lesion regression in a mouse model of surgically-induced endometriosis

    Article • Oncotarget, July 2018, Impact Journals, LLC

    Salvatore Cuzzocrea

  193. Dimethyl Fumarate Attenuates Neuroinflammation and Neurobehavioral Deficits Induced by Experimental Traumatic Brain Injury

    Article • Journal of Neurotrauma, July 2018, Mary Ann Liebert Inc

    Salvatore Cuzzocrea

  194. Sphingosine 1-Phosphate Receptor Subtype 1 as a Therapeutic Target for Brain Trauma

    Article • Journal of Neurotrauma, July 2018, Mary Ann Liebert Inc

    Salvatore Cuzzocrea

  195. Protective Effects of Xyloglucan in Association with the Polysaccharide Gelose in an Experimental Model of Gastroenteritis and Urinary Tract Infections

    Article • International Journal of Molecular Sciences, June 2018, MDPI AG

    Salvatore Cuzzocrea

  196. Evaluation of the Effect of a-L-Guluronic Acid (G2013) on COX-1, COX-2 Activity and Gene Expression for Introducing this Drug as a Novel NSAID with Immunomodulatory Property

    Article • Recent Patents on Inflammation & Allergy Drug Discovery, June 2018, Bentham Science Publishers

    Seyed Shahabeddin Mortazavi-Jahromi, Abbas Mirshafiey, Salvatore Cuzzocrea

  197. Anti-inflammatory effect of ATB-352, a H2S −releasing ketoprofen derivative, on lipopolysaccharide-induced periodontitis in rats

    Article • Pharmacological Research, June 2018, Elsevier

    Salvatore Cuzzocrea

  198. A phase I/II randomized, controlled, clinical trial for assessment of the efficacy and safety of β-d-mannuronic acid in rheumatoid arthritis patients

    Article • Inflammopharmacology, April 2018, Springer Science + Business Media

    Seyed Shahabeddin Mortazavi-Jahromi, Salvatore Cuzzocrea

  199. Effects of different natural extracts in an experimental model of benign prostatic hyperplasia (BPH)

    Article • Inflammation Research, April 2018, Springer Science + Business Media

    Salvatore Cuzzocrea

  200. 2-Pentadecyl-2-Oxazoline Reduces Neuroinflammatory Environment in the MPTP Model of Parkinson Disease

    Article • Molecular Neurobiology, April 2018, Springer Science + Business Media

    Salvatore Cuzzocrea

  201. Oral administration effects of β- d -mannuronic acid (M2000) on Th17 and regulatory T cells in patients with ankylosing spondylitis

    Article • Biomedicine & Pharmacotherapy, April 2018, Elsevier

    Seyed Shahabeddin Mortazavi-Jahromi, Salvatore Cuzzocrea

  202. Oral Ultramicronized Palmitoylethanolamide: Plasma and Tissue Levels and Spinal Anti-hyperalgesic Effect

    Article • Frontiers in Pharmacology, March 2018, Frontiers

    Salvatore Cuzzocrea

  203. N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice

    Article • Molecular Neurobiology, March 2018, Springer Science + Business Media

    Salvatore Cuzzocrea, Prof. Maurizio Evangelista

  204. Neuroinflammation and neurohormesis in the pathogenesis of Alzheimer’s disease and Alzheimer-linked pathologies: modulation by nutritional mushrooms

    Article • Immunity & Ageing, February 2018, Springer Science + Business Media

    Salvatore Cuzzocrea

  205. Neuronal-like differentiated SH-SY5Y cells adaptation to a mild and transient H2 O2 -induced oxidative stress

    Article • Cell Biochemistry and Function, February 2018, Wiley

    Salvatore Cuzzocrea

  206. The Antioxidant Activity of Pistachios Reduces Cardiac Tissue Injury of Acute Ischemia/Reperfusion (I/R) in Diabetic Streptozotocin (STZ)-Induced Hyperglycaemic Rats

    Article • Frontiers in Pharmacology, February 2018, Frontiers

    Salvatore Cuzzocrea

  207. Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis

    Article • Free Radical Biology and Medicine, February 2018, Elsevier

    Salvatore Cuzzocrea

  208. Bendamustine plus Rituximab Versus R‐CHOP as First‐Line Treatment for Patients with Follicular Lymphoma Grade 3A: Evidence from a Multicenter, Retrospective Study

    Article • The Oncologist, January 2018, Alphamed Press

    Salvatore Cuzzocrea

  209. Evaluation of the efficacy and safety of β-d-mannuronic acid in patients with ankylosing spondylitis: A 12-week randomized, placebo-controlled, phase I/II clinical trial

    Article • International Immunopharmacology, January 2018, Elsevier

    Salvatore Cuzzocrea

  210. A Controlled Cortical Impact Preclinical Model of Traumatic Brain Injury

    Article • December 2017, Springer Science + Business Media

    Salvatore Cuzzocrea

  211. An In Vivo Compression Model of Spinal Cord Injury

    Article • December 2017, Springer Science + Business Media

    Salvatore Cuzzocrea

  212. Middle Cerebral Artery Occlusion by an Intraluminal Suture Method

    Article • December 2017, Springer Science + Business Media

    Salvatore Cuzzocrea

  213. Fumaric Acid Esters Attenuate Secondary Degeneration after Spinal Cord Injury

    Article • Journal of Neurotrauma, November 2017, Mary Ann Liebert Inc

    Salvatore Cuzzocrea

  214. Multiple mechanisms of dimethyl fumarate in amyloid β-induced neurotoxicity in human neuronal cells

    Article • Journal of Cellular and Molecular Medicine, October 2017, Wiley

    Salvatore Cuzzocrea

  215. Introduction of β- d -mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression

    Article • Pharmacological Reports, October 2017, Elsevier

    Seyed Shahabeddin Mortazavi-Jahromi, Salvatore Cuzzocrea

  216. N-Palmitoylethanolamine-Oxazoline as a New Therapeutic Strategy to Control Neuroinflammation: Neuroprotective Effects in Experimental Models of Spinal Cord and Brain Injury

    Article • Journal of Neurotrauma, September 2017, Mary Ann Liebert Inc

    Salvatore Cuzzocrea

  217. The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson's Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-κB/Nuclear Transcription Factor Related to NF-E2

    Article • Antioxidants & Redox Signaling, September 2017, Mary Ann Liebert Inc

    Salvatore Cuzzocrea

  218. Palmitoylethanolamide and Polydatin combination reduces inflammation and oxidative stress in vascular injury

    Article • Pharmacological Research, September 2017, Elsevier

    Salvatore Cuzzocrea

  219. The Anti-Inflammatory and Antioxidant Potential of Pistachios (Pistacia vera L.) In Vitro and In Vivo

    Article • Nutrients, August 2017, MDPI AG

    Salvatore Cuzzocrea

  220. The effects of β-d-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the murine monocyte/macrophage, J774 cell line

    Article • Inflammopharmacology, August 2017, Springer Science + Business Media

    Salvatore Cuzzocrea

  221. AQX-1125, small molecule SHIP1 activator inhibits bleomycin-induced pulmonary fibrosis

    Article • British Journal of Pharmacology, August 2017, Wiley

    Salvatore Cuzzocrea

  222. The Potent Inhibitory Effect of β-D-Mannuronic Acid (M2000) as a Novel NSAID with Immunosuppressive Property on Anti-Cyclic Citrullinated Peptide Antibodies, Rheumatoid Factor and Anti-dsDNA Antibodies in Patients with Rheumatoid Arthritis

    Article • Current Drug Discovery Technologies, August 2017, Bentham Science Publishers

    Dr Mahdi Mahmoudi, Abbas Mirshafiey, Hossein Ahmadi, Salvatore Cuzzocrea

  223. A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models

    Article • BMC Veterinary Research, August 2017, Springer Science + Business Media

    Salvatore Cuzzocrea, Prof. Maurizio Evangelista

  224. Effects of a co-micronized composite containing palmitoylethanolamide and polydatin in an experimental model of benign prostatic hyperplasia

    Article • Toxicology and Applied Pharmacology, August 2017, Elsevier

    Salvatore Cuzzocrea

  225. Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia

    Article • Frontiers in Pharmacology, June 2017, Frontiers

    Salvatore Cuzzocrea

  226. Effect of a new formulation of micronized and ultramicronized N-palmitoylethanolamine in a tibia fracture mouse model of complex regional pain syndrome

    Article • PLoS ONE, June 2017, PLOS

    Salvatore Cuzzocrea, Prof. Maurizio Evangelista

  227. Anti-Inflammatory and Neuroprotective Effects of Co-UltraPEALut in a Mouse Model of Vascular Dementia

    Article • Frontiers in Neurology, June 2017, Frontiers

    Salvatore Cuzzocrea

  228. 2-Pentadecyl-2-Oxazoline, the Oxazoline of Pea, Modulates Carrageenan-Induced Acute Inflammation

    Article • Frontiers in Pharmacology, May 2017, Frontiers

    Salvatore Cuzzocrea

  229. Inhibition of inflammasome activation improves lung acute injury induced by carrageenan in a mouse model of pleurisy

    Article • The FASEB Journal, May 2017, Federation of American Societies For Experimental Biology (FASEB)

    Salvatore Cuzzocrea

  230. Potential Eye Drop Based on a Calix[4]arene Nanoassembly for Curcumin Delivery: Enhanced Drug Solubility, Stability, and Anti-Inflammatory Effect

    Article • Molecular Pharmaceutics, April 2017, American Chemical Society (ACS)

    Salvatore Cuzzocrea

  231. Liver X receptors activation, through TO901317 binding, reduces neuroinflammation in Parkinson’s disease

    Article • PLoS ONE, April 2017, PLOS

    Salvatore Cuzzocrea

  232. Neuroprotective Effects of Temsirolimus in Animal Models of Parkinson’s Disease

    Article • Molecular Neurobiology, March 2017, Springer Science + Business Media

    Salvatore Cuzzocrea

  233. Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases

    Article • British Journal of Pharmacology, March 2017, Wiley

    Salvatore Cuzzocrea

  234. A flavonoid-rich extract of orange juice reduced oxidative stress in an experimental model of inflammatory bowel disease

    Article • Journal of Functional Foods, March 2017, Elsevier

    Salvatore Cuzzocrea

  235. Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity

    Article • Journal of Medicinal Chemistry, February 2017, American Chemical Society (ACS)

    Salvatore Cuzzocrea

  236. FeTPPS Reduces Secondary Damage and Improves Neurobehavioral Functions after Traumatic Brain Injury

    Article • Frontiers in Neuroscience, February 2017, Frontiers

    Salvatore Cuzzocrea

  237. Laser-produced Au nanoparticles as X-ray contrast agents for diagnostic imaging

    Article • Gold Bulletin, January 2017, Springer Science + Business Media

    Salvatore Cuzzocrea

  238. Bone marrow micro-environment is a crucial player for myelomagenesis and disease progression

    Article • Oncotarget, January 2017, Impact Journals, LLC

    Salvatore Cuzzocrea

  239. Adelmidrol, in combination with hyaluronic acid, displays increased anti-inflammatory and analgesic effects against monosodium iodoacetate-induced osteoarthritis in rats

    Article • December 2016, Springer Science + Business Media

    prof maurizio evangelista, Prof. Maurizio Evangelista, Salvatore Cuzzocrea

  240. Hormesis, cellular stress response and neuroinflammation in schizophrenia: Early onset versus late onset state

    Article • Journal of Neuroscience Research, November 2016, Wiley

    Salvatore Cuzzocrea

  241. Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease

    Article • Journal of Neuroscience Research, November 2016, Wiley

    Salvatore Cuzzocrea

  242. Adelmidrol, a palmitoylethanolamide analogue, as a new pharmacological treatment for the management of acute and chronic inflammation

    Article • Biochemical Pharmacology, November 2016, Elsevier

    Salvatore Cuzzocrea

  243. Co-micronized Palmitoylethanolamide/Polydatin Treatment Causes Endometriotic Lesion Regression in a Rodent Model of Surgically Induced Endometriosis

    Article • Frontiers in Pharmacology, October 2016, Frontiers

    Prof. Maurizio Evangelista, Salvatore Cuzzocrea

  244. Traumatic Brain Injury Leads to Development of Parkinson's Disease Related Pathology in Mice

    Article • Frontiers in Neuroscience, October 2016, Frontiers

    Salvatore Cuzzocrea

  245. Beneficial Effects of Co-Ultramicronized Palmitoylethanolamide/Luteolin in a Mouse Model of Autism and in a Case Report of Autism

    Article • CNS Neuroscience & Therapeutics, October 2016, Wiley

    Salvatore Cuzzocrea

  246. PPAR-α Modulates the Anti-Inflammatory Effect of Melatonin in the Secondary Events of Spinal Cord Injury

    Article • Molecular Neurobiology, September 2016, Springer Science + Business Media

    Salvatore Cuzzocrea

  247. Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease

    Article • Molecular Pharmacology, September 2016, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Salvatore Cuzzocrea

  248. PARP inhibition treatment in a nonconventional experimental mouse model of chronic asthma

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, September 2016, Springer Science + Business Media

    Salvatore Cuzzocrea

  249. Ultramicronized palmitoylethanolamide (PEA-um ® ) in the treatment of idiopathic pulmonary fibrosis

    Article • Pharmacological Research, September 2016, Elsevier

    Salvatore Cuzzocrea

  250. Protective Effects of Ultramicronized Palmitoylethanolamide (PEA-um) in Myocardial Ischaemia and Reperfusion Injury in VIVO

    Article • Shock, August 2016, Wolters Kluwer Health

    Salvatore Cuzzocrea

  251. Anti-inflammatory and Antioxidant Effects of Flavonoid-Rich Fraction of Bergamot Juice (BJe) in a Mouse Model of Intestinal Ischemia/Reperfusion Injury

    Article • Frontiers in Pharmacology, July 2016, Frontiers

    Salvatore Cuzzocrea

  252. Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: relevance to Alzheimer’s disease pathogenesis

    Article • Immunity & Ageing, July 2016, Springer Science + Business Media

    Salvatore Cuzzocrea

  253. Lenalidomide in Relapsed or Refractory Diffuse Large B-Cell Lymphoma: Is It a Valid Treatment Option?

    Article • The Oncologist, July 2016, Alphamed Press

    Salvatore Cuzzocrea

  254. A new co-micronized composite containing palmitoylethanolamide and polydatin shows superior oral efficacy compared to their association in a rat paw model of carrageenan-induced inflammation

    Article • European Journal of Pharmacology, July 2016, Elsevier

    Salvatore Cuzzocrea

  255. Everolimus improves memory and learning while worsening depressive- and anxiety-like behavior in an animal model of depression

    Article • Journal of Psychiatric Research, July 2016, Elsevier

    Salvatore Cuzzocrea

  256. Thyroid hormone autoantibodies: are they a better marker to detect early thyroid damage in patients with hematologic cancers receiving tyrosine kinase inhibitor or immunoregulatory drug treatments?

    Article • Current Oncology, June 2016, MultiMed Inc.

    Salvatore Cuzzocrea

  257. 2-pentadecyl-2-oxazoline: Identification in coffee, synthesis and activity in a rat model of carrageenan-induced hindpaw inflammation

    Article • Pharmacological Research, June 2016, Elsevier

    Salvatore Cuzzocrea

  258. Erratum to: A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury

    Article • Journal of Neuroinflammation, May 2016, Springer Science + Business Media

    Salvatore Cuzzocrea

  259. Erratum to: Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain

    Article • Journal of Neuroinflammation, May 2016, Springer Science + Business Media

    Salvatore Cuzzocrea

  260. B-Cell Depletion with CD20 Antibodies as New Approach in the Treatment of Inflammatory and Immunological Events Associated with Spinal Cord Injury

    Article • Neurotherapeutics, May 2016, Springer Science + Business Media

    Salvatore Cuzzocrea

  261. The antioxidative property of melatonin against brain ischemia

    Article • Expert Review of Neurotherapeutics, May 2016, Taylor & Francis

    Salvatore Cuzzocrea

  262. Erratum to: Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice

    Article • May 2016, Springer Science + Business Media

    Salvatore Cuzzocrea

  263. Bendamustine plus rituximab versus R-CHOP as first-line treatment for patients with indolent non-Hodgkin’s lymphoma: evidence from a multicenter, retrospective study

    Article • Annals of Hematology, April 2016, Springer Science + Business Media

    Salvatore Cuzzocrea

  264. Neuroinflammation and Immunity: A New Pharmacological Target in Depression

    Article • CNS & Neurological Disorders - Drug Targets, March 2016, Bentham Science Publishers

    Salvatore Cuzzocrea

  265. Preventive and therapeutic effects of thymosin β4 N-terminal fragment Ac-SDKP in the bleomycin model of pulmonary fibrosis

    Article • Oncotarget, March 2016, Impact Journals, LLC

    Salvatore Cuzzocrea

  266. KU0063794, a Dual mTORC1 and mTORC2 Inhibitor, Reduces Neural Tissue Damage and Locomotor Impairment After Spinal Cord Injury in Mice

    Article • Molecular Neurobiology, March 2016, Springer Science + Business Media

    Salvatore Cuzzocrea

  267. Co-Ultramicronized Palmitoylethanolamide/Luteolin Promotes Neuronal Regeneration after Spinal Cord Injury

    Article • Frontiers in Pharmacology, March 2016, Frontiers

    Salvatore Cuzzocrea

  268. Redox modulation of cellular stress response and lipoxin A4 expression by Coriolus versicolor in rat brain: Relevance to Alzheimer's disease pathogenesis

    Article • NeuroToxicology, March 2016, Elsevier

    Salvatore Cuzzocrea

  269. 90Y-Ibritumomab-Tiuxetan Consolidation Therapy for Advanced-Stage Mantle Cell Lymphoma After First-Line Autologous Stem Cell Transplantation: Is It Time for a Step Forward?

    Article • Clinical Lymphoma Myeloma & Leukemia, February 2016, Elsevier

    Salvatore Cuzzocrea

  270. UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness

    Article • Cell, February 2016, Elsevier

    Salvatore Cuzzocrea

  271. A novel protective formulation of Palmitoylethanolamide in experimental model of contrast agent induced nephropathy

    Article • Toxicology Letters, January 2016, Elsevier

    Salvatore Cuzzocrea

  272. Repetitive Transcranial Magnetic Stimulation as a Novel Therapy in Animal Models of Traumatic Brain Injury

    Article • January 2016, Springer Science + Business Media

    Dr. SOUNDARA RAJAN THANGAVELU, Salvatore Cuzzocrea

  273. Neuroprotective Effects of Co-UltraPEALut on Secondary Inflammatory Process and Autophagy Involved in Traumatic Brain Injury

    Article • Journal of Neurotrauma, January 2016, Mary Ann Liebert Inc

    Salvatore Cuzzocrea

  274. Co-ultramicronized Palmitoylethanolamide/Luteolin in the Treatment of Cerebral Ischemia: from Rodent to Man

    Article • Translational Stroke Research, December 2015, Springer Science + Business Media

    Salvatore Cuzzocrea

  275. Dimethyl Fumarate Reduces Inflammatory Responses in Experimental Colitis

    Article • Journal of Crohn s and Colitis, December 2015, Oxford University Press (OUP)

    Salvatore Cuzzocrea

  276. 90 Y-ibritumomab tiuxetan: a nearly forgotten opportunity

    Article • Oncotarget, December 2015, Impact Journals, LLC

    Salvatore Cuzzocrea

  277. The anti-inflammatory and antioxidant effects of bergamot juice extract (BJe) in an experimental model of inflammatory bowel disease

    Article • Clinical Nutrition, December 2015, Elsevier

    Professor Michele Navarra, Salvatore Cuzzocrea

  278. Extranodal diffuse large B-cell lymphoma with monoclonal gammopathy: an aggressive and primary refractory disease responding to an immunomodulatory agent

    Article • Experimental Hematology and Oncology, December 2015, Springer Science + Business Media

    Salvatore Cuzzocrea

  279. Palmitoylethanolamide treatment reduces retinal inflammation in streptozotocin-induced diabetic rats

    Article • European Journal of Pharmacology, December 2015, Elsevier

    Salvatore Cuzzocrea

  280. Role of inflammation and apoptosis in multiple sclerosis: Comparative analysis between the periphery and the central nervous system

    Article • Journal of Neuroimmunology, October 2015, Elsevier

    Salvatore Cuzzocrea

  281. Role of the Renin-Angiotensin-Aldosterone System and Its Pharmacological Inhibitors in Cardiovascular Diseases: Complex and Critical Issues

    Article • High Blood Pressure & Cardiovascular Prevention, September 2015, Springer Science + Business Media

    Salvatore Cuzzocrea

  282. Role of Toll like receptor 4 signaling pathway in the secondary damage induced by experimental spinal cord injury

    Article • Immunobiology, September 2015, Elsevier

    Professor Michele Navarra, Salvatore Cuzzocrea

  283. Effects of palmitoylethanolamide and silymarin combination treatment in an animal model of kidney ischemia and reperfusion

    Article • European Journal of Pharmacology, September 2015, Elsevier

    Salvatore Cuzzocrea

  284. Protective effect of polyphenols in an inflammatory process associated with experimental pulmonary fibrosis in mice

    Article • British Journal Of Nutrition, August 2015, Cambridge University Press

    Salvatore Cuzzocrea

  285. The anti-inflammatory effects of palmitoylethanolamide (PEA) on endotoxin-induced uveitis in rats

    Article • European Journal of Pharmacology, August 2015, Elsevier

    Salvatore Cuzzocrea

  286. The Association of Palmitoylethanolamide with Luteolin Decreases Autophagy in Spinal Cord Injury

    Article • Molecular Neurobiology, July 2015, Springer Science + Business Media

    Salvatore Cuzzocrea

  287. Effects of thymosin β4 and its N-terminal fragment Ac-SDKP on TGF-β-treated human lung fibroblasts and in the mouse model of bleomycin-induced lung fibrosis

    Article • Expert Opinion on Biological Therapy, June 2015, Informa Healthcare

    Salvatore Cuzzocrea

  288. Emerging pharmacotherapy for treatment of traumatic brain injury: targeting hypopituitarism and inflammation

    Article • Expert Opinion on Emerging Drugs, June 2015, Informa Healthcare

    Salvatore Cuzzocrea

  289. N-Palmitoylethanolamine and Neuroinflammation: a Novel Therapeutic Strategy of Resolution

    Article • Molecular Neurobiology, June 2015, Springer Science + Business Media

    Salvatore Cuzzocrea

  290. Antineuropathic Profile of N-Palmitoylethanolamine in a Rat Model of Oxaliplatin-Induced Neurotoxicity

    Article • PLoS ONE, June 2015, PLOS

    Salvatore Cuzzocrea

  291. Inflammatory and Cell Death Pathways in Brain and Peripheral Blood in Parkinson’s Disease

    Article • CNS & Neurological Disorders - Drug Targets, April 2015, Bentham Science Publishers

    Salvatore Cuzzocrea

  292. Is radiotherapy still necessary for diffuse large B-cell lymphoma therapy?

    Article • Acta Oncologica, April 2015, Taylor & Francis

    Salvatore Cuzzocrea

  293. Role of natural antioxidants and potential use of bergamot in treating rheumatoid arthritis

    Article • PharmaNutrition, April 2015, Elsevier

    Salvatore Cuzzocrea

  294. Ultramicronized palmitoylethanolamide reduces inflammation an a Th1-mediated model of colitis

    Article • European Journal of Inflammation, April 2015, SAGE Publications

    Salvatore Cuzzocrea

  295. Long-term betamethasone 21-phosphate disodium treatment has distinct effects in CD1 and DBA/2 mice on animal behavior accompanied by opposite effects on neurogenesis

    Article • Behavioural Brain Research, February 2015, Elsevier

    Salvatore Cuzzocrea

  296. Emerging drugs for acute lung injury

    Article • Expert Opinion on Emerging Drugs, January 2015, Informa Healthcare

    Salvatore Cuzzocrea

  297. Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain

    Article • Pharmacological Research, January 2015, Elsevier

    Salvatore Cuzzocrea

  298. Neuroprotection by Association of Palmitoylethanolamide with Luteolin in Experimental Alzheimer’s Disease Models: The Control of Neuroinflammation

    Article • CNS & Neurological Disorders - Drug Targets, December 2014, Bentham Science Publishers

    Professor Michele Navarra, Salvatore Cuzzocrea

  299. A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways

    Article • Pain, December 2014, Wolters Kluwer Health

    Dr Kenneth A. Jacobson, Salvatore Cuzzocrea

  300. Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice

    Article • Journal of Neuroinflammation, December 2014, Springer Science + Business Media

    Salvatore Cuzzocrea

  301. Pim kinases in hematological malignancies: where are we now and where are we going?

    Article • Journal of Hematology & Oncology, December 2014, Springer Science + Business Media

    Salvatore Cuzzocrea

  302. Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain

    Article • Journal of Neuroinflammation, August 2014, Springer Science + Business Media

    Salvatore Cuzzocrea

  303. Roles of fatty acid ethanolamides (FAE) in traumatic and ischemic brain injury

    Article • Pharmacological Research, August 2014, Elsevier

    Salvatore Cuzzocrea

  304. Phosphodiesterase as a New Therapeutic Target for the Treatment of Spinal Cord Injury and Neurodegenerative Diseases

    Article • Current Medicinal Chemistry, July 2014, Bentham Science Publishers

    Salvatore Cuzzocrea

  305. Reply to Letter to Editor: “Kriek R., Marketing messages in pharmacological papers and scientific chapters: The case of palmitoylethanolamide and its formulations” [Pharmacol Res (2014) 10.1016/j.phrs.2014.04.007]

    Article • Pharmacological Research, July 2014, Elsevier

    Salvatore Cuzzocrea

  306. Osteoporosis and alzheimer pathology: Role of cellular stress response and hormetic redox signaling in aging and bone remodeling

    Article • Frontiers in Pharmacology, June 2014, Frontiers

    Salvatore Cuzzocrea

  307. Abandon the Mouse Research Ship? Not Just Yet!

    Article • Shock, June 2014, Wolters Kluwer Health

    Salvatore Cuzzocrea

  308. Thymosin β4 reduces IL-17-producing cells and IL-17 expression, and protects lungs from damage in bleomycin-treated mice

    Article • Immunobiology, June 2014, Elsevier

    Salvatore Cuzzocrea

  309. The Development and Maintenance of Paclitaxel-induced Neuropathic Pain Require Activation of the Sphingosine 1-Phosphate Receptor Subtype 1

    Article • Journal of Biological Chemistry, May 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Salvatore Cuzzocrea

  310. Costunolide and Dehydrocostuslactone, two natural sesquiterpene lactones, ameliorate the inflammatory process associated to experimental pleurisy in mice

    Article • European Journal of Pharmacology, May 2014, Elsevier

    Salvatore Cuzzocrea

  311. N-Palmitoylethanolamine Administration Ameliorates the Clinical Manifestation and Progression of Experimental Autoimmune Encephalomyelitis in Rodents

    Article • European Journal of Inflammation, May 2014, SAGE Publications

    Salvatore Cuzzocrea

  312. Pelagia noctiluca (Scyphozoa) Crude Venom Injection Elicits Oxidative Stress and Inflammatory Response in Rats

    Article • Marine Drugs, April 2014, MDPI AG

    Salvatore Cuzzocrea

  313. Targeting inflammation: New therapeutic approaches in chronic kidney disease (CKD)

    Article • Pharmacological Research, March 2014, Elsevier

    Salvatore Cuzzocrea

  314. Inflammation and Programmed Cell Death in Alzheimer’s Disease: Comparison of the Central Nervous System and Peripheral Blood

    Article • Molecular Neurobiology, January 2014, Springer Science + Business Media

    Salvatore Cuzzocrea

  315. Docosahexaenoic acid attenuates the early inflammatory response following spinal cord injury in mice: in-vivo and in-vitro studies

    Article • Journal of Neuroinflammation, January 2014, Springer Science + Business Media

    Salvatore Cuzzocrea

  316. Role of melatonin supplementation in neurodegenerative disorders

    Article • Frontiers in Bioscience, January 2014, Frontiers in Bioscience

    Salvatore Cuzzocrea

  317. Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice

    Article • November 2013, Springer Science + Business Media

    Salvatore Cuzzocrea

  318. Effects of Palmitoylethanolamide and Luteolin in an Animal Model of Anxiety/Depression

    Article • CNS & Neurological Disorders - Drug Targets, November 2013, Bentham Science Publishers

    Salvatore Cuzzocrea

  319. Bioenergetic deficits in peripheral nerve sensory axons during chemotherapy-induced neuropathic pain resulting from peroxynitrite-mediated post-translational nitration of mitochondrial superoxide dismutase

    Article • Pain, November 2013, Wolters Kluwer Health

    Salvatore Cuzzocrea

  320. Fluridone as a new anti-inflammatory drug

    Article • European Journal of Pharmacology, November 2013, Elsevier

    Salvatore Cuzzocrea

  321. Targeting selectins for the treatment of inflammatory diseases

    Article • Expert Opinion on Therapeutic Targets, September 2013, Informa Healthcare

    Salvatore Cuzzocrea

  322. Neuroimmune Pharmacology: An Emerging Discipline for the Italian Society of Pharmacology

    Article • Journal of Neuroimmune Pharmacology, September 2013, Springer Science + Business Media

    Salvatore Cuzzocrea

  323. Traumatic Brain Injury: Oxidative Stress and Neuroprotection

    Article • Antioxidants & Redox Signaling, September 2013, Mary Ann Liebert Inc

    Salvatore Cuzzocrea

  324. A hydrogen sulfide-releasing cyclooxygenase inhibitor markedly accelerates recovery from experimental spinal cord injury

    Article • The FASEB Journal, July 2013, Federation of American Societies For Experimental Biology (FASEB)

    Salvatore Cuzzocrea

  325. A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury

    Article • Journal of Neuroinflammation, July 2013, Springer Science + Business Media

    Professor Michele Navarra, Salvatore Cuzzocrea

  326. n-3 Fatty Acids: Role in Neurogenesis and Neuroplasticity

    Article • Current Medicinal Chemistry, July 2013, Bentham Science Publishers

    Salvatore Cuzzocrea

  327. Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance

    Article • Pain, July 2013, Wolters Kluwer Health

    Salvatore Cuzzocrea

  328. mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy

    Article • Neuropharmacology, June 2013, Elsevier

    Salvatore Cuzzocrea

  329. NADPH-oxidase 2 activation promotes opioid-induced antinociceptive tolerance in mice

    Article • Neuroscience, June 2013, Elsevier

    Salvatore Cuzzocrea

  330. Post-ischaemic thyroid hormone treatment in a rat model of acute stroke

    Article • Brain Research, June 2013, Elsevier

    Salvatore Cuzzocrea

  331. Effect of Almond Skins on a Lung Injury Model Elicited by Multirug-Resistant Pseudomonas Aeruginosa

    Article • European Journal of Inflammation, May 2013, SAGE Publications

    Salvatore Cuzzocrea

  332. Exogenous T3 administration provides neuroprotection in a murine model of traumatic brain injury

    Article • Pharmacological Research, April 2013, Elsevier

    Salvatore Cuzzocrea

  333. Absence of TLR4 Reduces Neurovascular Unit and Secondary Inflammatory Process after Traumatic Brain Injury in Mice

    Article • PLoS ONE, March 2013, PLOS

    Salvatore Cuzzocrea

  334. Combination therapy with melatonin and dexamethasone in a mouse model of traumatic brain injury

    Article • March 2013, Bioscientifica

    Salvatore Cuzzocrea

  335. Palmitoylethanolamide in Homeostatic and Traumatic Central Nervous System Injuries

    Article • CNS & Neurological Disorders - Drug Targets, March 2013, Bentham Science Publishers

    Salvatore Cuzzocrea

  336. Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma

    Article • Journal of Neuroinflammation, February 2013, Springer Science + Business Media

    Salvatore Cuzzocrea

  337. Sphingosine 1-Phosphate Mediates Hyperalgesia via a Neutrophil-Dependent Mechanism

    Article • PLoS ONE, January 2013, PLOS

    Salvatore Cuzzocrea

  338. Thymosin β4 protects C57BL/6 mice from bleomycin-induced damage in the lung

    Article • European Journal of Clinical Investigation, January 2013, Wiley

    Salvatore Cuzzocrea

  339. Green Tea

    Article • January 2013, Elsevier

    Salvatore Cuzzocrea

  340. Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes

    Article • Immunity & Ageing, January 2013, Springer Science + Business Media

    Salvatore Cuzzocrea

  341. The renal injury and inflammation caused by ischemia–reperfusion are reduced by genetic inhibition of TNF-αR1: A comparison with infliximab treatment

    Article • European Journal of Pharmacology, January 2013, Elsevier

    Salvatore Cuzzocrea

  342. Effects of a polyphenol present in olive oil, oleuropein aglycone, in a murine model of intestinal ischemia/reperfusion injury

    Article • Journal of Leukocyte Biology, December 2012, Wiley

    Salvatore Cuzzocrea

  343. Administration of palmitoylethanolamide (PEA) protects the neurovascular unit and reduces secondary injury after traumatic brain injury in mice

    Article • Brain Behavior and Immunity, November 2012, Elsevier

    Salvatore Cuzzocrea

  344. PALMITOYLETHANOLAMIDE REDUCES EARLY RENAL DYSFUNCTION AND INJURY CAUSED BY EXPERIMENTAL ISCHEMIA AND REPERFUSION IN MICE

    Article • Shock, October 2012, Wolters Kluwer Health

    Salvatore Cuzzocrea

  345. Reduction of ischemic brain injury by administration of palmitoylethanolamide after transient middle cerebral artery occlusion in rats

    Article • Brain Research, October 2012, Elsevier

    Salvatore Cuzzocrea

  346. Neuroprotective Activities of Palmitoylethanolamide in an Animal Model of Parkinson's Disease

    Article • PLoS ONE, August 2012, PLOS

    Salvatore Cuzzocrea

  347. Phenylpropanoid glycosides from plant cell cultures induce heme oxygenase 1 gene expression in a human keratinocyte cell line by affecting the balance of NRF2 and BACH1 transcription factors

    Article • Chemico-Biological Interactions, August 2012, Elsevier

    Salvatore Cuzzocrea

  348. Peroxisome proliferator-activated receptor β/δ agonist GW0742 ameliorates cerulein- and taurocholate-induced acute pancreatitis in mice

    Article • Surgery, July 2012, Elsevier

    Salvatore Cuzzocrea

  349. Effect of Fasudil, a Selective Inhibitor of Rho Kinase Activity, in the Secondary Injury Associated with the Experimental Model of Spinal Cord Trauma

    Article • Journal of Pharmacology and Experimental Therapeutics, June 2012, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Salvatore Cuzzocrea

  350. In vitro and in vivo properties of a fully human IgG1 monoclonal antibody that combats multidrug resistant Pseudomonas aeruginosa

    Article • International Journal of Molecular Medicine, June 2012, Spandidos Publications

    Salvatore Cuzzocrea

  351. Effects of palmitoylethanolamide on intestinal injury and inflammation caused by ischemia-reperfusion in mice

    Article • Journal of Leukocyte Biology, June 2012, Wiley

    Salvatore Cuzzocrea

  352. Targeting the Overproduction of Peroxynitrite for the Prevention and Reversal of Paclitaxel-Induced Neuropathic Pain

    Article • Journal of Neuroscience, May 2012, Society for Neuroscience

    Salvatore Cuzzocrea

  353. The effects of a polyphenol present in olive oil, oleuropein aglycone, in an experimental model of spinal cord injury in mice

    Article • Biochemical Pharmacology, May 2012, Elsevier

    Salvatore Cuzzocrea

  354. Pharmacological and clinical overview of cloperastine in treatment of cough

    Article • Therapeutics and Clinical Risk Management, March 2011, Taylor & Francis

    Salvatore Cuzzocrea

  355. Modulation of nitric oxide homeostasis in a mouse model of spinal cord injury

    Article • Journal of Neurosurgery Spine, February 2006, Journal of Neurosurgery Publishing Group (JNSPG)

    Salvatore Cuzzocrea