All Stories

  1. The histone code reader PHD finger protein 7 controls sex-linked disparities in gene expression and malignancy in Drosophila

    Article • Science Advances, August 2019, American Association for the Advancement of Science

    Professor Cayetano Gonzalez

  2. Centrobin is essential for C-tubule assembly and flagellum development in Drosophila melanogaster spermatogenesis

    Article • The Journal of Cell Biology, April 2018, Rockefeller University Press

    Professor Cayetano Gonzalez

  3. Drosophila Larval Brain Neoplasms Present Tumour-Type Dependent Genome Instability

    Article • G3 Genes Genomes Genetics, February 2018, Genetics Society of America

    Professor Cayetano Gonzalez

  4. An in vivo genetic screen in Drosophila identifies the orthologue of human cancer/testis gene SPO11 among a network of targets to inhibit lethal(3)malignan...

    Article • Open Biology, August 2017, Royal Society Publishing

    Professor Cayetano Gonzalez

  5. Prefoldin and Pins synergistically regulate asymmetric division and suppress dedifferentiation

    Article • Scientific Reports, March 2016, Nature

    Professor Cayetano Gonzalez

  6. Arl2- and Msps-dependent microtubule growth governs asymmetric division

    Article • The Journal of Cell Biology, March 2016, Rockefeller University Press

    Professor Cayetano Gonzalez

  7. The translational relevance ofDrosophilain drug discovery

    Article • EMBO Reports, February 2016, EMBO

    Professor Cayetano Gonzalez

  8. A last-minute decision

    Article • Nature, December 2015, Springer Science + Business Media

    Professor Cayetano Gonzalez

  9. Studying tumor growth in Drosophila using the tissue allograft method

    Article • Nature Protocols, September 2015, Springer Science + Business Media

    Professor Cayetano Gonzalez

  10. Loss of Centrobin Enables Daughter Centrioles to Form Sensory Cilia in Drosophila

    Article • Current Biology, August 2015, Elsevier

    Professor Cayetano Gonzalez

  11. Time-lapse recording of centrosomes and other organelles in Drosophila neuroblasts

    Article • January 2015, Elsevier

    Professor Cayetano Gonzalez

  12. Quantitative differences, qualitative outcomes

    Article • eLife, October 2014, eLife

    Professor Cayetano Gonzalez

  13. When fate follows age: unequal centrosomes in asymmetric cell division

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, July 2014, Royal Society Publishing

    Professor Cayetano Gonzalez

  14. The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

    Article • eLife, March 2014, eLife

    Hongyan Wang, Professor Cayetano Gonzalez, Dr Song Li, Dr Paul Robson, Dr Sherry S Aw

  15. Structure and Non-Structure of Centrosomal Proteins

    Article • PLoS ONE, May 2013, PLOS

    Professor Guillermo Montoya, Professor Cayetano Gonzalez

  16. Drosophila melanogaster: a model and a tool to investigate malignancy and identify new therapeutics

    Article • Nature Reviews Cancer, February 2013, Springer Science + Business Media

    Professor Cayetano Gonzalez

  17. Centrobin controls mother–daughter centriole asymmetry in Drosophila neuroblasts

    Article • Nature Cell Biology, January 2013, Springer Science + Business Media

    Professor Cayetano Gonzalez

  18. On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN

    Article • Open Biology, August 2012, Royal Society Publishing

    Professor Cayetano Gonzalez

  19. Drosophila Mgr, a Prefoldin subunit cooperating with von Hippel Lindau to regulate tubulin stability

    Article • Proceedings of the National Academy of Sciences, March 2012, Proceedings of the National Academy of Sciences

    Professor Cayetano Gonzalez

  20. Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics

    Article • BMC Cancer, January 2012, Springer Science + Business Media

    Professor Cayetano Gonzalez

  21. Synergism between altered cortical polarity and the PI3K/TOR pathway in the suppression of tumour growth

    Article • EMBO Reports, December 2011, EMBO

    Professor Cayetano Gonzalez

  22. An Ana2/Ctp/Mud Complex Regulates Spindle Orientation in Drosophila Neuroblasts

    Article • Developmental Cell, September 2011, Elsevier

    Professor Cayetano Gonzalez, Dr Song Li

  23. Drosophila neuroblasts retain the daughter centrosome

    Article • Nature Communications, March 2011, Springer Science + Business Media

    Professor Cayetano Gonzalez

  24. Ectopic Expression of Germline Genes Drives Malignant Brain Tumor Growth in Drosophila

    Article • Science, December 2010, American Association for the Advancement of Science

    Professor Cayetano Gonzalez

  25. Interplay between the Transcription Factor Zif and aPKC Regulates Neuroblast Polarity and Self-Renewal

    Article • Developmental Cell, November 2010, Elsevier

    Professor Cayetano Gonzalez

  26. Neural stem cells: the need for a proper orientation

    Article • Current Opinion in Genetics & Development, August 2010, Elsevier

    Professor Cayetano Gonzalez

  27. Time‐Lapse Imaging of Embryonic Neural Stem Cell Division in Drosophila by Two‐Photon Microscopy

    Article • Current Protocols in Stem Cell Biology, June 2010, Wiley

    Professor Cayetano Gonzalez

  28. The interphase microtubule aster is a determinant of asymmetric division orientation inDrosophilaneuroblasts

    Article • The Journal of Cell Biology, March 2010, Rockefeller University Press

    Professor Cayetano Gonzalez

  29. Biased segregation of DNA and centrosomes — moving together or drifting apart?

    Article • Nature Reviews Molecular Cell Biology, November 2009, Springer Science + Business Media

    Professor Cayetano Gonzalez

  30. Spindle alignment is achieved without rotation after the first cell cycle in Drosophila embryonic neuroblasts

    Article • Development, September 2009, The Company of Biologists

    Professor Cayetano Gonzalez

  31. Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling

    Article • Nature Genetics, September 2009, Springer Science + Business Media

    Professor Cayetano Gonzalez

  32. 08-P016 Maintenance of the orientation of polarity in Drosophila larval brain neuroblasts

    Article • Mechanisms of Development, August 2009, Elsevier

    Professor Cayetano Gonzalez

  33. S07-05 Neural stem cell polarity and malignant growth in Drosophila

    Article • Mechanisms of Development, August 2009, Elsevier

    Professor Cayetano Gonzalez

  34. Below the Convergence

    Article • Current Biology, April 2009, Elsevier

    Professor Cayetano Gonzalez

  35. Centrosome function during stem cell division: the devil is in the details

    Article • Current Opinion in Cell Biology, December 2008, Elsevier

    Professor Cayetano Gonzalez

  36. Drosophila asymmetric division, polarity and cancer

    Article • Oncogene, November 2008, Springer Science + Business Media

    Professor Cayetano Gonzalez

  37. Centrosome Dysfunction in Drosophila Neural Stem Cells Causes Tumors that Are Not Due to Genome Instability

    Article • Current Biology, August 2008, Elsevier

    Professor Cayetano Gonzalez

  38. Cayetano Gonzalez

    Article • Current Biology, January 2008, Elsevier

    Professor Cayetano Gonzalez

  39. Spermatocyte cytokinesis requires rapid membrane addition mediated by ARF6 on central spindle recycling endosomes

    Article • Development, December 2007, The Company of Biologists

    Professor Cayetano Gonzalez

  40. Asterless Is a Centriolar Protein Required for Centrosome Function and Embryo Development in Drosophila

    Article • Current Biology, October 2007, Elsevier

    Professor Cayetano Gonzalez

  41. Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells

    Article • Nature Reviews Genetics, June 2007, Springer Science + Business Media

    Professor Cayetano Gonzalez

  42. Functionally Unequal Centrosomes Drive Spindle Orientation in Asymmetrically Dividing Drosophila Neural Stem Cells

    Article • Developmental Cell, March 2007, Elsevier

    Professor Cayetano Gonzalez

  43. Localized transfection with magnetic beads coated with PCR products and other nucleic acids

    Article • Nature Protocols, June 2006, Springer Science + Business Media

    Professor Cayetano Gonzalez

  44. Connecting Cancer to the Asymmetric Division of Stem Cells

    Article • Cell, March 2006, Elsevier

    Professor Cayetano Gonzalez

  45. Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster

    Article • Nature Genetics, September 2005, Springer Science + Business Media

    Professor Cayetano Gonzalez

  46. Structure and microtubule-nucleation activity of isolated Drosophila embryo centrosomes characterized by whole mount scanning and transmission electron microscopy

    Article • Histochemistry and Cell Biology, August 2005, Springer Science + Business Media

    Professor Cayetano Gonzalez

  47. Localized transfection on arrays of magnetic beads coated with PCR products

    Article • Nature Methods, January 2005, Springer Science + Business Media

    Professor Cayetano Gonzalez

  48. Contribution of Noncentrosomal Microtubules to Spindle Assembly in Drosophila Spermatocytes

    Article • PLoS Biology, January 2004, PLOS

    Professor Cayetano Gonzalez

  49. γ-Tubulin function during female germ-cell development and oogenesis in Drosophila

    Article • Proceedings of the National Academy of Sciences, August 2003, Proceedings of the National Academy of Sciences

    Professor Cayetano Gonzalez

  50. Cell Division: The Place and Time of Cytokinesis

    Article • Current Biology, April 2003, Elsevier

    Professor Cayetano Gonzalez

  51. Drosophila dd4 mutants reveal that gammaTuRC is required to maintain juxtaposed half spindles in spermatocytes

    Article • Journal of Cell Science, January 2003, The Company of Biologists

    Professor Cayetano Gonzalez

  52. Cdc37 is essential for chromosome segregation and cytokinesis in higher eukaryotes

    Article • The EMBO Journal, October 2002, Wiley

    Professor Cayetano Gonzalez

  53. Computer-aided design of a PDZ domain to recognize new target sequences

    Article • Nature Structural Biology, June 2002, Springer Science + Business Media

    Professor Cayetano Gonzalez

  54. Miranda, a protein involved in neuroblast asymmetric division, is associated with embryonic centrosomes of Drosophila melanogaster

    Article • Biology of the Cell, February 2002, Wiley

    Professor Cayetano Gonzalez

  55. Organized microtubule arrays in γ-tubulin-depleted Drosophila spermatocytes

    Article • Current Biology, November 2001, Elsevier

    Professor Cayetano Gonzalez

  56. Requirement of Hsp90 for centrosomal function reflects its regulation of Polo kinase stability

    Article • The EMBO Journal, June 2001, Wiley

    Professor Cayetano Gonzalez

  57. Patterns of Cell Division and Expression of Asymmetric Cell Fate Determinants in Postembryonic Neuroblast Lineages of Drosophila

    Article • Developmental Biology, February 2001, Elsevier

    Professor Cayetano Gonzalez

  58. Dominant-negative mutant dynein allows spontaneous centrosome assembly, uncouples chromosome and centrosome cycles

    Article • Current Biology, January 2001, Elsevier

    Professor Cayetano Gonzalez

  59. Light, flies and cell division

    Article • EMBO Reports, November 2000, EMBO

    Professor Cayetano Gonzalez

  60. Vaccinia virus infection disrupts microtubule organization and centrosome function

    Article • The EMBO Journal, August 2000, Springer Science + Business Media

    Professor Cayetano Gonzalez

  61. Visualizing the spindle checkpoint inDrosophilaspermatocytes

    Article • EMBO Reports, July 2000, EMBO

    Professor Cayetano Gonzalez

  62. Protein traps: using intracellular localization for cloning

    Article • Trends in Cell Biology, April 2000, Elsevier

    Professor Cayetano Gonzalez

  63. Interactions between mgr , asp , and polo : asp function modulated by polo and needed to maintain the poles of monopolar and bipolar spindles

    Article • Chromosoma, December 1998, Springer Science + Business Media

    Professor Cayetano Gonzalez

  64. Microinjection of Drosophila Eggs

    Article • January 1998, Springer Science + Business Media

    Professor Cayetano Gonzalez

  65. TheDrosophilaGeneabnormal spindleEncodes a Novel Microtubule-associated Protein That Associates with the Polar Regions of the Mitotic Spindle

    Article • The Journal of Cell Biology, May 1997, Rockefeller University Press

    Professor Cayetano Gonzalez

  66. Essential role for gamma -tubulin in the acentriolar female meiotic spindle of Drosophila

    Article • The EMBO Journal, April 1997, Wiley

    Professor Cayetano Gonzalez

  67. 16 Methods in Drosophila Cell Cycle Biology

    Article • January 1997, Elsevier

    Professor Cayetano Gonzalez

  68. Transposable elements map in a conserved pattern of distribution extending from beta-heterochromatin to centromeres in Drosophila melanogaster

    Article • Chromosoma, August 1995, Springer Science + Business Media

    Professor Cayetano Gonzalez

  69. Molecular analysis of ribosomal DNA from the aphid Amphorophora idaei and an associated fungal organism

    Article • Insect Molecular Biology, August 1994, Wiley

    Professor Cayetano Gonzalez

  70. Cell Cycle Genes of Drosophila

    Article • January 1994, Elsevier

    Professor Cayetano Gonzalez

  71. The Centrosome

    Article • Scientific American, June 1993, Springer Science + Business Media

    Professor Cayetano Gonzalez, Professor Jordan Raff

  72. Cell type-specific gene expression in the Drosophila melanogaster male accessory gland

    Article • Mechanisms of Development, July 1992, Elsevier

    Professor Cayetano Gonzalez

  73. Regulation of the G1-S transition in postembryonic neuronal precursors by axon ingrowth

    Article • Nature, January 1992, Springer Science + Business Media

    Professor Cayetano Gonzalez

  74. Applications of confocal laser scanning microscopy

    Article • Trends in Cell Biology, December 1991, Elsevier

    Professor Cayetano Gonzalez

  75. polo encodes a protein kinase homolog required for mitosis in Drosophila.

    Article • Genes & Development, December 1991, Cold Spring Harbor Laboratory Press

    Professor Cayetano Gonzalez

  76. The spindle is required for the process of sister chromatid separation in Drosophila neuroblasts

    Article • Experimental Cell Research, January 1991, Elsevier

    Professor Cayetano Gonzalez

  77. Cyclical Changes in the Subcellular Distribution of Proteins Essential for Mitosis during Embryogenesis in Drosophila

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1991, Cold Spring Harbor Laboratory Press

    Professor Cayetano Gonzalez

  78. Relationship between chromosome content and nuclear diameter in early spermatids ofDrosophila melanogaster

    Article • Genetics Research, December 1989, Hindawi Publishing Corporation

    Professor Cayetano Gonzalez

  79. Transcripts of one of two Drosophila cyclin genes become localized in pole cells during embryogenesis

    Article • Nature, March 1989, Springer Science + Business Media

    Professor Cayetano Gonzalez

  80. Towards the genetic dissection of mitosis inDrosophila

    Article • BioEssays, November 1987, Wiley

    Professor Cayetano Gonzalez

  81. Time-Lapse Imaging of Male Meiosis by Phase-Contrast and Fluorescence Microscopy

    Article • Springer Science + Business Media

    Professor Cayetano Gonzalez