All Stories

  1. TIPICO IX: report of the 9th interactive infectious disease workshop on infectious diseases and vaccines

    Article • Human Vaccines & Immunotherapeutics, June 2019, Taylor & Francis

    Federico Martinon-Torres, Jose GOMEZ RIAL, Professor Carlos Martin, Professor Adam Finn

  2. Active TB versus Latent TB, a M. tuberculosis decisison

    Article • January 2019, ASM Journals

    Professor Carlos Martin

  3. New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages

    Article • PLoS Genetics, April 2018, PLOS

    Professor Carlos Martin

  4. Vacunación frente a tuberculosis

    Article • Enfermedades Infecciosas y Microbiología Clínica, April 2018, Elsevier

    Professor Carlos Martin

  5. Data-driven model for the assessment of Mycobacterium tuberculosis transmission in evolving demographic structures

    Article • Proceedings of the National Academy of Sciences, March 2018, Proceedings of the National Academy of Sciences

    Professor Carlos Martin

  6. MTBVAC: Attenuating the Human Pathogen of Tuberculosis (TB) Toward a Promising Vaccine against the TB Epidemic

    Article • Frontiers in Immunology, December 2017, Frontiers

    Professor Carlos Martin

  7. Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis

    Article • Nature Communications, July 2017, Nature

    Professor Carlos Martin

  8. MTBVAC live-attenuated M. tuberculosis Vaccine in Clinical Trials

    Article • Expert Review of Vaccines, May 2017, Taylor & Francis

    Professor Carlos Martin

  9. Evaluation of the Mycobacterium tuberculosis SO 2 vaccine using a natural tuberculosis infection model in goats

    Article • The Veterinary Journal, May 2017, Elsevier

    Professor Carlos Martin, Christian Gortazar

  10. Detection of a Putative TetR-Like Gene Related to Mycobacterium bovis BCG Growth in Cholesterol Using a gfp-Transposon Mutagenesis System

    Article • Frontiers in Microbiology, March 2017, Frontiers

    Professor Carlos Martin

  11. A data-driven model for the assessment of Tuberculosis transmission in evolving demographic structures.

    Article • February 2017, Cold Spring Harbor Laboratory Press

    Professor Carlos Martin

  12. Revaccination of Guinea Pigs With the Live Attenuated Mycobacterium tuberculosis Vaccine MTBVAC Improves BCG's Protection Against Tuberculosis

    Article • The Journal of Infectious Diseases, January 2017, Oxford University Press (OUP)

    Professor Carlos Martin

  13. Tuberculosis Vaccines

    Article • January 2017, Springer Science + Business Media

    Professor Carlos Martin

  14. Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

    Article • Journal of Visualized Experiments, September 2016, MyJove Corporation

    Professor Carlos Martin

  15. In-depth analysis of the genome sequence of a clinical, extensively drug-resistant Mycobacterium bovis strain

    Article • Tuberculosis, September 2016, Elsevier

    Professor Carlos Martin

  16. Vaccination Against Tuberculosis With Whole-Cell Mycobacterial Vaccines

    Article • The Journal of Infectious Diseases, May 2016, Oxford University Press (OUP)

    Professor Carlos Martin

  17. Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

    Article • PLoS ONE, April 2016, PLOS

    Professor Carlos Martin

  18. On the impact of masking and blocking hypotheses for measuring the efficacy of new tuberculosis vaccines

    Article • PeerJ, February 2016, PeerJ

    Professor Carlos Martin

  19. Mycobacterial diversity causing multi- and extensively drug-resistant tuberculosis in Djibouti, Horn of Africa

    Article • The International Journal of Tuberculosis and Lung Disease, February 2016, International Union Against Tuberculosis and Lung Disease

    Professor Carlos Martin

  20. MTBVAC vaccine is safe, immunogenic and confers protective efficacy against Mycobacterium tuberculosis in newborn mice

    Article • Tuberculosis, January 2016, Elsevier

    Professor Carlos Martin

  21. Evaluation of the immunogenicity and diagnostic interference caused by M. tuberculosis SO2 vaccination against tuberculosis in goats

    Article • Research in Veterinary Science, December 2015, Elsevier

    Professor Carlos Martin

  22. Safety of human immunisation with a live-attenuated Mycobacterium tuberculosis vaccine: a randomised, double-blind, controlled phase I trial

    Article • The Lancet Respiratory Medicine, December 2015, Elsevier

    Professor Carlos Martin

  23. Pulmonary but Not Subcutaneous Delivery of BCG Vaccine Confers Protection to Tuberculosis-Susceptible Mice by an Interleukin 17–Dependent Mechanism

    Article • The Journal of Infectious Diseases, October 2015, Oxford University Press (OUP)

    Professor Carlos Martin

  24. Evolutionary Landscape of the Mycobacterium tuberculosis Complex from the Viewpoint of PhoPR: Implications for Virulence Regulation and Application to Vaccine Development

    Article • mBio, October 2015, ASM Journals

    Professor Carlos Martin

  25. Klebsiella pneumoniaesurvives within macrophages by avoiding delivery to lysosomes

    Article • Cellular Microbiology, July 2015, Wiley

    Professor Carlos Martin

  26. Developing whole mycobacteria cell vaccines for tuberculosis: Workshop proceedings, Max Planck Institute for Infection Biology, Berlin, Germany, July 9, 2014

    Article • Vaccine, June 2015, Elsevier

    Professor Carlos Martin

  27. In VivoIS6110Profile Changes in a Mycobacterium tuberculosis Strain as Determined by Tracking over 14 Years

    Article • Journal of Clinical Microbiology, May 2015, ASM Journals

    Professor Carlos Martin

  28. Editorial Commentary: Nonspecific Beneficial Effects of BCG Vaccination in High-income Countries, Should We Extend Recommendation of BCG Vaccination?

    Article • Clinical Infectious Diseases, February 2015, Oxford University Press (OUP)

    Professor Carlos Martin

  29. Hyper-attenuated MTBVAC erp mutant protects against tuberculosis in mice

    Article • Vaccine, September 2014, Elsevier

    Professor Carlos Martin

  30. Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator

    Article • Proceedings of the National Academy of Sciences, July 2014, Proceedings of the National Academy of Sciences

    Professor Carlos Martin

  31. Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis

    Article • Cell Death and Disease, July 2014, Nature

    Professor Carlos Martin

  32. A Specific Polymorphism in Mycobacterium tuberculosis H37Rv Causes Differential ESAT-6 Expression and Identifies WhiB6 as a Novel ESX-1 Component

    Article • Infection and Immunity, June 2014, ASM Journals

    Professor Carlos Martin, Wafa FRIGUI

  33. The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis

    Article • PLoS Pathogens, May 2014, PLOS

    Professor Carlos Martin

  34. Pulmonary Mycobacterium bovis BCG Vaccination Confers Dose-Dependent Superior Protection Compared to That of Subcutaneous Vaccination

    Article • Clinical and Vaccine Immunology, February 2014, ASM Journals

    Professor Carlos Martin

  35. Single nucleotide polymorphism (SNP) analysis used for the phylogeny of the Mycobacterium tuberculosis complex based on a pyrosequencing assay

    Article • BMC Microbiology, January 2014, Springer Science + Business Media

    Professor Carlos Martin

  36. Recent developments in tuberculosis vaccines

    Article • Expert Review of Vaccines, December 2013, Taylor & Francis

    Professor Carlos Martin

  37. MTBVAC

    Article • Vaccine, October 2013, Elsevier

    Professor Carlos Martin

  38. Global Study of IS6110in a Successful Mycobacterium tuberculosis Strain: Clues for Deciphering Its Behavior and for Its Rapid Detection

    Article • Journal of Clinical Microbiology, August 2013, ASM Journals

    Professor Carlos Martin

  39. ESX-1-induced apoptosis is involved in cell-to-cell spread ofMycobacterium tuberculosis

    Article • Cellular Microbiology, August 2013, Wiley

    Professor Carlos Martin

  40. ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question

    Article • Frontiers in Cellular and Infection Microbiology, January 2013, Frontiers

    Professor Carlos Martin

  41. Mapping IS6110 in high-copy number Mycobacterium tuberculosis strains shows specific insertion points in the Beijing genotype

    Article • BMC Genomics, January 2013, Springer Science + Business Media

    Professor Carlos Martin

  42. Attenuated Mycobacterium tuberculosis SO2 Vaccine Candidate Is Unable to Induce Cell Death

    Article • PLoS ONE, September 2012, PLOS

    Professor Carlos Martin

  43. Conspicuous multidrug-resistant Mycobacterium tuberculosis cluster strains do not trespass country borders in Latin America and Spain

    Article • Infection Genetics and Evolution, June 2012, Elsevier

    Professor Carlos Martin, Jacobus de Waard

  44. Long-term molecular surveillance of multidrug-resistant tuberculosis in Spain

    Article • Infection Genetics and Evolution, June 2012, Elsevier

    Professor Carlos Martin

  45. Functional and Genetic Characterization of the Tap Efflux Pump in Mycobacterium bovis BCG

    Article • Antimicrobial Agents and Chemotherapy, January 2012, ASM Journals

    Professor Carlos Martin

  46. IS-seq: a novel high throughput survey of in vivo IS6110 transposition in multiple Mycobacterium tuberculosis genomes

    Article • BMC Genomics, January 2012, Springer Science + Business Media

    Maria Mercedes Zambrano, Professor Carlos Martin

  47. Protective immunity afforded by attenuated, PhoP-deficientMycobacterium tuberculosisis associated with sustained generation of CD4+T-cell memory

    Article • European Journal of Immunology, December 2011, Wiley

    Professor Carlos Martin

  48. Rapid Test for Identification of a Highly Transmissible Mycobacterium tuberculosis Beijing Strain of Sub-Saharan Origin

    Article • Journal of Clinical Microbiology, November 2011, ASM Journals

    Professor Carlos Martin

  49. The Transcriptional Regulatory Network of Mycobacterium tuberculosis

    Article • PLoS ONE, July 2011, PLOS

    Professor Carlos Martin

  50. Vacunación frente a la tuberculosis

    Article • Anales de Pediatría Continuada, May 2011, Elsevier

    Professor Carlos Martin

  51. New tuberculosis vaccines

    Article • Enfermedades Infecciosas y Microbiología Clínica, March 2011, Elsevier

    Professor Carlos Martin

  52. Deciphering the role of IS6110 in a highly transmissible Mycobacterium tuberculosis Beijing strain, GC1237

    Article • Tuberculosis, March 2011, Elsevier

    Professor Carlos Martin

  53. Interactions of Attenuated Mycobacterium tuberculosis phoP Mutant with Human Macrophages

    Article • PLoS ONE, September 2010, PLOS

    Professor Carlos Martin

  54. High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling

    Article • PLoS Pathogens, September 2010, PLOS

    Professor Carlos Martin

  55. Drug-resistant tuberculosis in the European Union: Opportunities and challenges for control

    Article • Tuberculosis, May 2010, Elsevier

    Professor Carlos Martin

  56. Multidrug-ResistantMycobacterium tuberculosisStrain from Equatorial Guinea Detected in Spain

    Article • Emerging Infectious Diseases, November 2009, Centers for Disease Control and Prevention (CDC)

    Professor Carlos Martin

  57. Role of the Mycobacterium tuberculosis P55 Efflux Pump in Intrinsic Drug Resistance, Oxidative Stress Responses, and Growth

    Article • Antimicrobial Agents and Chemotherapy, June 2009, ASM Journals

    Santiago Ramon Garcia, Professor Carlos Martin

  58. MVA.85A Boosting of BCG and an Attenuated, phoP Deficient M. tuberculosis Vaccine Both Show Protective Efficacy Against Tuberculosis in Rhesus Macaques

    Article • PLoS ONE, April 2009, PLOS

    Professor Carlos Martin

  59. Extended safety studies of the attenuated live tuberculosis vaccine SO2 based on phoP mutant

    Article • Vaccine, April 2009, Elsevier

    Professor Carlos Martin

  60. Corrigendum to “Mapping of IS6110 insertion sites in Mycobacterium bovis isolates in relation to adaptation from the animal to human host” [Vet. Microbiol. 129 (2008) 333–341]

    Article • Veterinary Microbiology, March 2009, Elsevier

    Professor Carlos Martin

  61. Unsuspected and extensive transmission of a drug-susceptible Mycobacterium tuberculosisstrain

    Article • BMC Pulmonary Medicine, January 2009, Springer Science + Business Media

    Professor Carlos Martin

  62. Intracellular replication of attenuated Mycobacterium tuberculosis phoP mutant in the absence of host cell cytotoxicity

    Article • Microbes and Infection, January 2009, Elsevier

    Professor Carlos Martin

  63. PhoP: A Missing Piece in the Intricate Puzzle of Mycobacterium tuberculosis Virulence

    Article • PLoS ONE, October 2008, PLOS

    Professor Carlos Martin

  64. Attenuated strains of Mycobacterium tuberculosis complex for laboratory and clinical use

    Article • Tuberculosis, September 2008, Elsevier

    Professor Carlos Martin

  65. The Mycobacterium tuberculosis phoPR Operon Is Positively Autoregulated in the Virulent Strain H37Rv

    Article • Journal of Bacteriology, August 2008, ASM Journals

    Professor Carlos Martin

  66. Mapping of IS6110 insertion sites in Mycobacterium bovis isolates in relation to adaptation from the animal to human host

    Article • Veterinary Microbiology, June 2008, Elsevier

    Professor Carlos Martin

  67. Live tuberculosis vaccines based onphoPmutants: a step towards clinical trials

    Article • Expert Opinion on Biological Therapy, January 2008, Informa Healthcare

    Professor Carlos Martin

  68. Control of M. tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP

    Article • PLoS Pathogens, January 2008, PLOS

    Professor Carlos Martin, Wafa FRIGUI

  69. A Point Mutation in the Two-Component Regulator PhoP-PhoR Accounts for the Absence of Polyketide-Derived Acyltrehaloses but Not That of Phthiocerol Dimycocerosates in Mycobacterium tuberculosis H37Ra

    Article • Journal of Bacteriology, December 2007, ASM Journals

    Professor Carlos Martin

  70. Multidrug-resistant Mycobacterium tuberculosis Beijing/W genotype in Venezuela

    Article • Journal of Medical Microbiology, December 2007, Society for General Microbiology

    Professor Carlos Martin

  71. Transcriptional analysis of and resistance level conferred by the aminoglycoside acetyltransferase gene aac(2')-Id from Mycobacterium smegmatis

    Article • Journal of Antimicrobial Chemotherapy, November 2007, Oxford University Press (OUP)

    Professor Carlos Martin

  72. Recurrent tuberculosis from 1992 to 2004 in a metropolitan area

    Article • European Respiratory Journal, August 2007, European Respiratory Society (ERS)

    Professor Carlos Martin

  73. Spread of Extensively Drug-resistant Tuberculosis

    Article • Emerging Infectious Diseases, April 2007, Centers for Disease Control and Prevention (CDC)

    Professor Carlos Martin

  74. Contribution of the Rv2333c efflux pump (the Stp protein) from Mycobacterium tuberculosis to intrinsic antibiotic resistance in Mycobacterium bovis BCG

    Article • Journal of Antimicrobial Chemotherapy, January 2007, Oxford University Press (OUP)

    Professor Carlos Martin

  75. Immunological responses and protective immunity against tuberculosis conferred by vaccination of Balb/C mice with the attenuated Mycobacterium tuberculosis (phoP) SO2 strain

    Article • Clinical & Experimental Immunology, December 2006, Wiley

    Professor Carlos Martin

  76. Novel Streptomycin Resistance Gene from Mycobacterium fortuitum

    Article • Antimicrobial Agents and Chemotherapy, September 2006, ASM Journals

    Santiago Ramon Garcia, Professor Carlos Martin

  77. Tuberculosis vaccines: past, present and future

    Article • Current Opinion in Pulmonary Medicine, May 2006, Wolters Kluwer Health

    Professor Carlos Martin

  78. The use of mutant mycobacteria as new vaccines to prevent tuberculosis

    Article • Tuberculosis, May 2006, Elsevier

    Professor Carlos Martin

  79. The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs

    Article • Vaccine, April 2006, Elsevier

    Professor Carlos Martin

  80. Characterization of tetracycline resistance mediated by the efflux pump Tap from Mycobacterium fortuitum

    Article • Journal of Antimicrobial Chemotherapy, February 2006, Oxford University Press (OUP)

    Professor Carlos Martin

  81. Article • BMC Microbiology, January 2006, Springer Science + Business Media

    Professor Carlos Martin

  82. Article • BMC Microbiology, January 2006, Springer Science + Business Media

    Professor Carlos Martin, Dr Enrico Tortoli

  83. Neutral-red reaction is related to virulence and cell wall methyl-branched lipids in Mycobacterium tuberculosis

    Article • Microbes and Infection, January 2006, Elsevier

    Professor Carlos Martin

  84. Cefotetan-induced hemolytic anemia after perioperative prophylaxis

    Article • American Journal of Hematology, January 2006, Wiley

    Professor Carlos Martin

  85. The Virulence-associated Two-component PhoP-PhoR System Controls the Biosynthesis of Polyketide-derived Lipids inMycobacterium tuberculosis

    Article • Journal of Biological Chemistry, December 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Carlos Martin

  86. Revisiting the Evolution of Mycobacterium bovis

    Article • Journal of Bacteriology, September 2005, ASM Journals

    Professor Carlos Martin

  87. The dream of a vaccine against tuberculosis; new vaccines improving or replacing BCG?

    Article • European Respiratory Journal, July 2005, European Respiratory Society (ERS)

    Professor Carlos Martin

  88. Systematic Molecular Characterization of Multidrug-Resistant Mycobacterium tuberculosis Complex Isolates from Spain

    Article • Journal of Clinical Microbiology, March 2005, ASM Journals

    Professor Carlos Martin

  89. Molecular characterization of Mycobacterium tuberculosis complex isolates from wild ungulates in south-central Spain

    Article • Veterinary Research, January 2005, EDP Sciences

    Ursula Hofle Hansen, Professor Carlos Martin, Christian Gortazar

  90. Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis

    Article • Tuberculosis, January 2005, Elsevier

    Professor Carlos Martin

  91. Mycobacterium smegmatisdisplays theMycobacterium tuberculosisvirulence-related neutral red character when expressing theRv0577gene

    Article • FEMS Microbiology Letters, February 2004, Oxford University Press (OUP)

    Professor Carlos Martin

  92. IS6110 Mediates Increased Transcription of the phoP Virulence Gene in a Multidrug-Resistant Clinical Isolate Responsible for Tuberculosis Outbreaks

    Article • Journal of Clinical Microbiology, January 2004, ASM Journals

    Professor Carlos Martin

  93. Epidemiology of tuberculosis on Gran Canaria: a 4 year population study using traditional and molecular approaches

    Article • Thorax, July 2003, BMJ

    Professor Carlos Martin

  94. Mycobacterium tuberculosis phoP mutant: lipoarabinomannan molecular structure

    Article • Microbiology, October 2002, Society for General Microbiology

    Professor Carlos Martin

  95. An essential role for phoP in Mycobacterium tuberculosis virulence

    Article • Molecular Microbiology, December 2001, Wiley

    Professor Carlos Martin

  96. Molecular approaches to tuberculosis

    Article • Molecular Microbiology, October 2001, Wiley

    Professor Carlos Martin

  97. Characterization of P55, a Multidrug Efflux Pump inMycobacterium bovis and Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, March 2001, ASM Journals

    Professor Carlos Martin

  98. Transmission between HIV-infected patients of multidrug-resistant tuberculosis caused by Mycobacterium bovis

    Article • AIDS, August 1997, Wolters Kluwer Health

    Professor Carlos Martin

  99. Construction of a family of Mycobacterium/Escherichia coli shuttle vectors derived from pAL5000 and pACYC184: their use for cloning an antibiotic-resistance gene from Mycobacterium fortuitum

    Article • Gene, October 1996, Elsevier

    Professor Carlos Martin

  100. Use of conjugative and thermosensitive cloning vectors for transposon delivery to Mycobacterium smegmatis

    Article • FEMS Microbiology Letters, March 1995, Oxford University Press (OUP)

    Professor Carlos Martin

  101. New Methods for Diagnosis and Epidemiological Studies of Tuberculosis based on PCR and RFLP

    Article • January 1994, Springer Science + Business Media

    Professor Carlos Martin

  102. Onopordum nervosum as biomass source: Some aspects of its production and transformation by enzymatic hydrolysis

    Article • Bioresource Technology, January 1993, Elsevier

    Professor Carlos Martin

  103. Analysis of the regions responsible for IS6110 RFLP in a single Mycobacterium tuberculosis strain

    Article • Research in Microbiology, January 1992, Elsevier

    Professor Carlos Martin

  104. Transposition of an antibiotic resistance element in mycobacteria

    Article • Nature, June 1990, Nature

    Professor Carlos Martin

  105. Factors that affect transposition mediated by the Tn21 transposase

    Article • Plasmid, July 1988, Elsevier

    Professor Carlos Martin

  106. Aminoglycoside-phosphotransferases APH(3′)-IV and APH(3″) synthesized by a strain of Campylobacter coli

    Article • Journal of Antimicrobial Chemotherapy, January 1986, Oxford University Press (OUP)

    Professor Carlos Martin