All Stories

  1. New models of atherosclerosis and multi-drug therapeutic interventions
  2. Can we devise new therapies by combining databases of protein interactions and of drug targets?
  3. Coincidence versus consequence: opportunities in multi-morbidity research and inflammation as a pervasive feature
  4. Computational modelling of atherosclerosis
  5. Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-
  6. A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway
  7. A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction
  8. The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response
  9. Digital clocks: simple Boolean models can quantitatively describe circadian systems
  10. Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis
  11. The in silico macrophage: toward a better understanding of inflammatory disease
  12. Use of logic theory in understanding regulatory pathway signaling in response to infection
  13. Construction of a large scale integrated map of macrophage pathogen recognition and effector systems
  14. The Systems Biology Graphical Notation
  15. Logic models of pathway biology
  16. Inferring Boolean networks with perturbation from sparse gene expression data: a general model applied to the interferon regulatory network