All Stories

  1. A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs

    Article • Acta Crystallographica Section D Structural Biology, February 2022, International Union of Crystallography

    Dr Alexei S Soares, Herbert J Bernstein

  2. Best practices for high data-rate macromolecular crystallography (HDRMX)

    Article • Structural Dynamics, January 2020, American Institute of Physics

    Research Scholar Herbert J. Bernstein, Dr Alexei S Soares, lawremce Andrews, Jean Jakoncic, Herbert J Bernstein

  3. Using sound pulses to solve the crystal-harvesting bottleneck

    Article • Acta Crystallographica Section D Structural Biology, October 2018, International Union of Crystallography

    Dr Alexei S Soares

  4. Maintaining Microclimates during Nanoliter Chemical Dispensations Using Custom-Designed Source Plate Lids

    Article • SLAS TECHNOLOGY, February 2016, SAGE Publications

    Dr Alexei S Soares

  5. Acoustic Methods to Monitor Protein Crystallization and to Detect Protein Crystals in Suspensions of Agarose and Lipidic Cubic Phase

    Article • SLAS TECHNOLOGY, February 2016, SAGE Publications

    Dr Alexei S Soares, Mr Richard N Ellson

  6. Acoustic transfer of protein crystals from agarose pedestals to micromeshes for high-throughput screening

    Article • Acta Crystallographica Section D Biological Crystallography, January 2015, International Union of Crystallography

    Dr Alexei S Soares

  7. A simple technique to reduce evaporation of crystallization droplets by using plate lids with apertures for adding liquids

    Article • Acta Crystallographica Section F Structural Biology Communications, November 2014, International Union of Crystallography

    Dr Alexei S Soares

  8. Solvent minimization induces preferential orientation and crystal clustering in serial micro-crystallography on micro-meshes,in situplates and on a movable crystal conveyor belt

    Article • Journal of Synchrotron Radiation, October 2014, International Union of Crystallography

    Dr Alexei S Soares

  9. A Linear Relationship between Crystal Size and Fragment Binding Time Observed Crystallographically: Implications for Fragment Library Screening Using Acoustic Droplet Ejection

    Article • PLoS ONE, July 2014, PLOS

    Dr Alexei S Soares

  10. Crystallographic characterization of the nitric oxide derivative of R-state human hemoglobin

    Article • Nitric Oxide, May 2014, Elsevier

    Dr Alexei S Soares

  11. Hitting the target: fragment screening with acousticin situco-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes

    Article • Acta Crystallographica Section D Biological Crystallography, April 2014, International Union of Crystallography

    Dr Alexei S Soares

  12. Macromolecular crystallography beamline X25 at the NSLS

    Article • Journal of Synchrotron Radiation, April 2014, International Union of Crystallography

    Dr Alexei S Soares

  13. Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes

    Article • PLoS ONE, September 2013, PLOS

    Dr Alexei S Soares

  14. Acoustic methods for high-throughput protein crystal mounting at next-generation macromolecular crystallographic beamlines

    Article • Journal of Synchrotron Radiation, August 2013, International Union of Crystallography

    Dr Alexei S Soares, Dr Joe Olechno, Mr Richard N Ellson

  15. Presence versus absence of hydrogen bond donor Tyr‐39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors

    Article • Protein Science, June 2012, Wiley

    Dr Alexei S Soares

  16. Structure of the catalytic chain ofMethanococcus jannaschiiaspartate transcarbamoylase in a hexagonal crystal form: insights into the path of carbamoyl phosphate to the active site of the enzyme

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, April 2012, International Union of Crystallography

    Dr Alexei S Soares

  17. The P 2 ′ residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity

    Article • Biochemical Journal, November 2011, Portland Press Ltd.

    Dr Alexei S Soares

  18. Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures

    Article • Biochemistry, May 2011, American Chemical Society (ACS)

    Dr Alexei S Soares, Dr Joe Olechno, Mr Richard N Ellson

  19. Structural Basis for NADH/NAD+ Redox Sensing by a Rex Family Repressor

    Article • Molecular Cell, May 2010, Elsevier

    Dr Alexei S Soares

  20. Expression, purification and preliminary diffraction studies of CmlS

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, February 2009, International Union of Crystallography

    Dr Alexei S Soares

  21. Remote Access to the PXRR Macromolecular Crystallography Facilities at the NSLS

    Article • Synchrotron Radiation News, September 2008, Taylor & Francis

    Dr Alexei S Soares

  22. Expression, purification and preliminary diffraction studies of PhnP

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, May 2008, International Union of Crystallography

    Dr Alexei S Soares, Bjarne Hove-Jensen

  23. Crystal Structure of a Complex between the Phosphorelay Protein YPD1 and the Response Regulator Domain of SLN1 Bound to a Phosphoryl Analog

    Article • Journal of Molecular Biology, January 2008, Elsevier

    Dr Alexei S Soares

  24. Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site

    Article • BMC Structural Biology, January 2007, Springer Science + Business Media

    Dr Alexei S Soares

  25. Mail-in crystallography program at Brookhaven National Laboratory's National Synchrotron Light Source

    Article • Acta Crystallographica Section D Biological Crystallography, October 2006, International Union of Crystallography

    Dr Alexei S Soares

  26. Integrated software for macromolecular crystallography synchrotron beamlines II: revision, robots and a database

    Article • Acta Crystallographica Section D Biological Crystallography, October 2006, International Union of Crystallography

    Dr Alexei S Soares

  27. Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin

    Article • Journal of Inorganic Biochemistry, August 2006, Elsevier

    Dr Alexei S Soares

  28. P170. NO and nitrite with iron porphyrins: A structural perspective

    Article • Nitric Oxide, June 2006, Elsevier

    Dr Alexei S Soares

  29. Experimental methods for measuring accurate high-amplitude phases and their importance in isomorphous replacement experiments

    Article • Acta Crystallographica Section D Biological Crystallography, October 2005, International Union of Crystallography

    Dr Alexei S Soares

  30. First results of digital topography applied to macromolecular crystals

    Article • Journal of Applied Crystallography, May 2004, International Union of Crystallography

    Dr Alexei S Soares, Dr Edward H Snell

  31. Three-beam interference is a sensitive measure of the efficacy of macromolecular refinement techniques

    Article • Acta Crystallographica Section D Biological Crystallography, September 2003, International Union of Crystallography

    Dr Alexei S Soares, Dr Edgar Franz Weckert

  32. Quantitative Assessment of Peptide Sequence Diversity in M13 Combinatorial Peptide Phage Display Libraries

    Article • Journal of Molecular Biology, October 2002, Elsevier

    Dr Alexei S Soares