All Stories

  1. Comparative biotransformation of luteolin and apigenin from the flower extract and the stem‐and‐leaf extract of Dendranthema morifolium Ramat. Tzvel. in rats

    Article • Journal of the Science of Food and Agriculture, February 2021, Wiley

    Dr Lie-Chwen Lin

  2. Pharmacokinetics of quercetin-loaded nanodroplets with ultrasound activation and their use for bioimaging

    Article • International Journal of Nanomedicine, April 2015, Taylor & Francis

    Dr Lie-Chwen Lin, Dr Mei-Ling Hou, Dr SHUO HUI HUNG

  3. Pharmacokinetics of Ractopamine and Its Organ Distribution in Rats

    Article • Journal of Agricultural and Food Chemistry, September 2014, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  4. Comparative pharmacokinetics of rhein in normal and loperamide-induced constipated rats and microarray analysis of drug-metabolizing genes

    Article • Journal of Ethnopharmacology, September 2014, Elsevier

    Dr Lie-Chwen Lin

  5. Isolation and Cytotoxic Effect of Anthraquinones from Morinda umbellata

    Article • Planta Medica, August 2014, Thieme Publishing Group

    Dr Lie-Chwen Lin

  6. Development of a microdialysis system to monitor lamivudine in blood and liver for the pharmacokinetic application in herbal drug interaction and the gene expression in rats

    Article • Journal of Pharmaceutical and Biomedical Analysis, August 2014, Elsevier

    Dr Lie-Chwen Lin

  7. Determination of protein‐unbound rhynchiphylline brain distribution by microdialysis and ultra‐performance liquid chromatography with tandem mass spectrometry

    Article • Biomedical Chromatography, May 2014, Wiley

    Dr Lie-Chwen Lin

  8. Determination of Bioactive Components in Chinese Herbal Formulae and Pharmacokinetics of Rhein in Rats by UPLC-MS/MS

    Article • Molecules, April 2014, MDPI AG

    Dr Lie-Chwen Lin

  9. Lignans from the Aerial Parts of Saururus chinensis: Isolation, Structural Characterization, and Their Effects on Platelet Aggregation

    Article • Journal of Natural Products, January 2014, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  10. Comparative oral bioavailability of geniposide following oral administration of geniposide, Gardenia jasminoides  Ellis fruits extracts and Gardenia herbal formulation in rats

    Article • Journal of Pharmacy and Pharmacology, December 2013, Oxford University Press (OUP)

    Dr Lie-Chwen Lin

  11. Pharmacokinetics and oral bioavailability of epimedin C after oral administration of epimedin C and Herba Epimedii extract in rats

    Article • Biomedical Chromatography, November 2013, Wiley

    Dr Lie-Chwen Lin

  12. Determination of rhynchophylline and hirsutine in rat plasma by UPLC‐MS/MS after oral administration of Uncaria rhynchophylla extract

    Article • Biomedical Chromatography, October 2013, Wiley

    Dr Lie-Chwen Lin

  13. Chemical constituents comparison ofCodonopsis tangshenCodonopsis pilosulavar. modesta andCodonopsis pilosula

    Article • Natural Product Research, October 2013, Taylor & Francis

    Dr Lie-Chwen Lin

  14. Determination and Pharmacokinetics of Di-(2-ethylhexyl) Phthalate in Rats by Ultra Performance Liquid Chromatography with Tandem Mass Spectrometry

    Article • Molecules, September 2013, MDPI AG

    Dr Lie-Chwen Lin

  15. Herb-Drug Interaction of Epimedium sagittatum (Sieb. et Zucc.) Maxim Extract on the Pharmacokinetics of Sildenafil in Rats

    Article • Molecules, June 2013, MDPI AG

    Dr Lie-Chwen Lin

  16. Comment on Pharmacokinetics and Urine Metabolite Identification of Dehydroevodiamine in the Rat: From Boymia ruticarpa A. Juss. toTetradium ruticarpum (A. Juss.) T.G. Hartley

    Article • Journal of Agricultural and Food Chemistry, January 2013, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  17. Chemical and Physical Methods to Analyze a Multicomponent Traditional Chinese Herbal Prescription Using LC-MS/MS, Electron Microscope, and Congo Red Staining

    Article • Evidence-based Complementary and Alternative Medicine, January 2013, Hindawi Publishing Corporation

    Dr Lie-Chwen Lin

  18. New Alkaloids and Cytotoxic Principles from Sinomenium acutum

    Article • Planta Medica, October 2012, Thieme Publishing Group

    Dr Lie-Chwen Lin

  19. Chemical Analysis and Transplacental Transfer of Oseltamivir and Oseltamivir Carboxylic Acid in Pregnant Rats

    Article • PLoS ONE, October 2012, PLOS

    Dr Lie-Chwen Lin

  20. HPLC–MS/MS Analysis of a Traditional Chinese Medical Formulation of Bu-Yang-Huan-Wu-Tang and Its Pharmacokinetics after Oral Administration to Rats

    Article • PLoS ONE, August 2012, PLOS

    Dr Lie-Chwen Lin

  21. Effects of polymer molecular weight on relative oral bioavailability of curcumin

    Article • International Journal of Nanomedicine, June 2012, Taylor & Francis

    Dr Lie-Chwen Lin

  22. Isolation of gentiopicroside from Gentianae Radix and its pharmacokinetics on liver ischemia/reperfusion rats

    Article • Journal of Ethnopharmacology, June 2012, Elsevier

    Dr Lie-Chwen Lin

  23. Neobavaisoflavone stimulates osteogenesis via p38-mediated up-regulation of transcription factors and osteoid genes expression in MC3T3-E1 cells

    Article • Phytomedicine, April 2012, Elsevier

    Dr Lie-Chwen Lin

  24. Pharmacokinetics and Urine Metabolite Identification of Dehydroevodiamine in the Rat

    Article • Journal of Agricultural and Food Chemistry, February 2012, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  25. Curcumin and its nano-formulation: The kinetics of tissue distribution and blood–brain barrier penetration

    Article • International Journal of Pharmaceutics, September 2011, Elsevier

    Dr Lie-Chwen Lin

  26. 5-Deoxyflavones with Cytotoxic Activity from Mimosa diplotricha

    Article • Journal of Natural Products, August 2011, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  27. A novel 8.O.6′-neolignan fromTaxillus theifer

    Article • Natural Product Research, August 2011, Taylor & Francis

    Dr Lie-Chwen Lin

  28. Optimised nano-formulation on the bioavailability of hydrophobic polyphenol, curcumin, in freely-moving rats

    Article • Food Chemistry, August 2011, Elsevier

    Dr Lie-Chwen Lin

  29. Effects of a P-glycoprotein modulator on the pharmacokinetics and distribution of free levobupivacaine and bupivacaine in rats

    Article • International Journal of Pharmaceutics, August 2010, Elsevier

    Dr Lie-Chwen Lin

  30. Analysis of Biliary Excretion of Icariin in Rats

    Article • Journal of Agricultural and Food Chemistry, August 2010, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  31. Anti‐Proliferative Effects of Evodiamine on Human Thyroid Cancer Cell Line ARO

    Article • Journal of Cellular Biochemistry, July 2010, Wiley

    Dr Lie-Chwen Lin

  32. Pharmacokinetics of Adenosine and Cordycepin, a Bioactive Constituent of Cordyceps sinensis in Rat

    Article • Journal of Agricultural and Food Chemistry, March 2010, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  33. Herb–drug interaction of Andrographis paniculata extract and andrographolide on the pharmacokinetics of theophylline in rats

    Article • Chemico-Biological Interactions, March 2010, Elsevier

    Dr Lie-Chwen Lin

  34. Oral Bioavailability, Urinary Excretion and Organ Distribution of Melamine in Sprague−Dawley Rats by High-Performance Liquid Chromatography with Tandem Mass Spectrometry

    Article • Journal of Agricultural and Food Chemistry, December 2009, American Chemical Society (ACS)

    Dr Lie-Chwen Lin, Professor Der-Cherng Tarng

  35. Herb–drug interaction of silymarin or silibinin on the pharmacokinetics of trazodone in rats

    Article • Chemico-Biological Interactions, December 2009, Elsevier

    Dr Lie-Chwen Lin

  36. Determination of melamine in rat plasma, liver, kidney, spleen, bladder and brain by liquid chromatography–tandem mass spectrometry

    Article • Journal of Chromatography A, October 2009, Elsevier

    Dr Lie-Chwen Lin, Professor Der-Cherng Tarng

  37. Lanostanes from Phellinus igniarius and Their iNOS Inhibitory Activities

    Article • Planta Medica, June 2009, Thieme Publishing Group

    Dr Lie-Chwen Lin

  38. ChemInform Abstract: Phenolic Glycosides and Pyrrolidine Alkaloids from Codonopsis tangshen

    Article • ChemInform, April 2009, Wiley

    Dr Lie-Chwen Lin

  39. Measurement of free hydroxytyrosol in microdialysates from blood and brain of anesthetized rats by liquid chromatography with fluorescence detection

    Article • Journal of Chromatography A, April 2009, Elsevier

    Dr Lie-Chwen Lin

  40. Lanostane-triterpenoids from the fungus Phellinus gilvus

    Article • Phytochemistry, March 2009, Elsevier

    Dr Lie-Chwen Lin

  41. Drug–drug interactions of silymarin on the perspective of pharmacokinetics

    Article • Journal of Ethnopharmacology, January 2009, Elsevier

    Dr Lie-Chwen Lin

  42. Pharmacokinetics of kadsurenone and its interaction with cyclosporin A in rats using a combined HPLC and microdialysis system

    Article • Journal of Chromatography B, January 2009, Elsevier

    Dr Lie-Chwen Lin

  43. Food–drug interaction of (−)-epigallocatechin-3-gallate on the pharmacokinetics of irinotecan and the metabolite SN-38

    Article • Chemico-Biological Interactions, August 2008, Elsevier

    Dr Lie-Chwen Lin

  44. Vasorelaxing Alkaloids and Flavonoids from Cassytha filiformis

    Article • Journal of Natural Products, January 2008, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  45. Phenolic Glycosides and Pyrrolidine Alkaloids from Codonopsis tangshen

    Article • Chemical and Pharmaceutical Bulletin, January 2008, Pharmaceutical Society of Japan

    Dr Lie-Chwen Lin

  46. Analysis of silibinin in rat plasma and bile for hepatobiliary excretion and oral bioavailability application

    Article • Journal of Pharmaceutical and Biomedical Analysis, November 2007, Elsevier

    Dr Lie-Chwen Lin

  47. Prenylflavonol, acylated flavonol glycosides and related compounds from Epimedium sagittatum

    Article • Phytochemistry, October 2007, Elsevier

    Dr Lie-Chwen Lin

  48. Anti-Inflammatory Ergostanes from the Basidiomata of Antrodia salmonea

    Article • Planta Medica, September 2007, Thieme Publishing Group

    Dr Lie-Chwen Lin

  49. Liquid chromatographic method with amperometric detection to determine acteoside in rat blood and brain microdialysates and its application to pharmacokinetic study

    Article • Journal of Chromatography B, June 2007, Elsevier

    Dr Lie-Chwen Lin

  50. Selective COX-2 inhibitors. Part 1: Synthesis and biological evaluation of phenylazobenzenesulfonamides

    Article • Bioorganic & Medicinal Chemistry Letters, September 2006, Elsevier

    Dr Lie-Chwen Lin

  51. Pharmacokinetics of protein-unbound linezolid in the blood and the mechanism of hepatobiliary excretion in the rat

    Article • Analytica Chimica Acta, June 2006, Elsevier

    Dr Lie-Chwen Lin

  52. Pharmacokinetics and brain distribution of unbound levamisole in the anesthetized rats using microdialysis and microbore column liquid chromatography

    Article • Analytica Chimica Acta, May 2006, Elsevier

    Dr Lie-Chwen Lin

  53. Anti-inflammatory Neolignans from Piper kadsura

    Article • Journal of Natural Products, May 2006, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  54. Hepatobiliary excretion and brain distribution of caffeine in rats using microdialysis

    Article • Analytica Chimica Acta, May 2006, Elsevier

    Dr Lie-Chwen Lin

  55. Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity

    Article • Life Sciences, April 2006, Elsevier

    Dr Lie-Chwen Lin

  56. Simultaneous determination of honokiol and magnolol in Magnolia officinalis by liquid chromatography with tandem mass spectrometric detection

    Article • Biomedical Chromatography, April 2006, Wiley

    Dr Lie-Chwen Lin

  57. Determination and pharmacokinetics of evodiamine in the plasma and feces of conscious rats

    Article • Analytica Chimica Acta, February 2006, Elsevier

    Dr Lie-Chwen Lin

  58. Rossicasins A, B and Rosicaside F, Three New Phenylpropanoid Glycosides from Boschniakia rossica

    Article • Chemical and Pharmaceutical Bulletin, January 2006, Pharmaceutical Society of Japan

    Dr Lie-Chwen Lin

  59. Elimination of rutaecarpine and its metabolites in rat feces and urine measured by liquid chromatography

    Article • Biomedical Chromatography, January 2006, Wiley

    Dr Lie-Chwen Lin

  60. The inhibitory effect of phenylpropanoid glycosides and iridoid glucosides on free radical production and β2 integrin expression in human leucocytes

    Article • Journal of Pharmacy and Pharmacology, January 2006, Oxford University Press (OUP)

    Dr Lie-Chwen Lin

  61. New Lanostanes and Naphthoquinones Isolated from Antrodia salmonea and their Antioxidative Burst Activity in Human Leukocytes

    Article • Planta Medica, January 2006, Thieme Publishing Group

    Dr Lie-Chwen Lin

  62. Herb–drug interaction of Evodia rutaecarpa extract on the pharmacokinetics of theophylline in rats

    Article • Journal of Ethnopharmacology, December 2005, Elsevier

    Dr Lie-Chwen Lin

  63. Effects of Evodia rutaecarpa and Rutaecarpine on the Pharmacokinetics of Caffeine in Rats

    Article • Planta Medica, July 2005, Thieme Publishing Group

    Dr Lie-Chwen Lin

  64. Measurement of daphnoretin in plasma of freely moving rat by liquid chromatography

    Article • Journal of Chromatography A, May 2005, Elsevier

    Dr Lie-Chwen Lin

  65. Isolation and Immunomodulatory Effect of Flavonoids from Syzygium samarangense

    Article • Planta Medica, December 2004, Thieme Publishing Group

    Dr Lie-Chwen Lin

  66. Acteoside protects endothelial cells against free radical-induced oxidative stress

    Article • Journal of Pharmacy and Pharmacology, June 2004, Oxford University Press (OUP)

    Dr Lie-Chwen Lin

  67. Determination of (−)-epigallocatechin gallate in rat blood by microdialysis coupled with liquid chromatography

    Article • Journal of Chromatography A, April 2004, Elsevier

    Dr Lie-Chwen Lin

  68. Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP

    Article • International Journal of Cancer, March 2004, Wiley

    Dr Lie-Chwen Lin

  69. Cytotoxic naphthoquinones and plumbagic acid glucosides from Plumbago zeylanica

    Article • Phytochemistry, February 2003, Elsevier

    Dr Lie-Chwen Lin

  70. Pharmacokinetic study of free mangiferin in rats by microdialysis coupled with microbore high-performance liquid chromatography and tandem mass spectrometry

    Article • Journal of Chromatography A, February 2003, Elsevier

    Dr Lie-Chwen Lin

  71. Effects of evodiamine on gastrointestinal motility in male rats

    Article • European Journal of Pharmacology, December 2002, Elsevier

    Dr Lie-Chwen Lin

  72. Immunomodulatory functions of extracts from the Chinese medicinal fungus Cordyceps cicadae

    Article • Journal of Ethnopharmacology, November 2002, Elsevier

    Dr Lie-Chwen Lin

  73. Effect of timosaponin A-III, from Anemarrhenae asphodeloides Bunge (Liliaceae), on calcium mobilization in vascular endothelial and smooth muscle cells and on vascular tension

    Article • Life Sciences, July 2002, Elsevier

    Dr Lie-Chwen Lin

  74. Immunomodulatory Proanthocyanidins from Ecdysanthera utilis

    Article • Journal of Natural Products, March 2002, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  75. Induction of cytochrome P450-dependent monooxygenase in mouse liver and kidney by rutaecarpine, an alkaloid of the herbal drug Evodia rutaecarpa

    Article • Life Sciences, November 2001, Elsevier

    Dr Lie-Chwen Lin

  76. Cytotoxic Principles from Ventilago leiocarpa

    Article • Journal of Natural Products, May 2001, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  77. Flavonoids and Phenolics from Limonium sinense

    Article • Planta Medica, May 2000, Thieme Publishing Group

    Dr Lie-Chwen Lin

  78. Anti-Herpes Simplex Virus Type-1 Flavonoids and a New Flavanone from the Root of Limonium sinense

    Article • Planta Medica, May 2000, Thieme Publishing Group

    Dr Lie-Chwen Lin

  79. Cytotoxic Biflavonoids from Selaginella delicatula

    Article • Journal of Natural Products, April 2000, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  80. Flavonoid Glycosides from Viscum alniformosanae

    Article • Journal of Natural Products, September 1999, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  81. Immunomodulatory Principles of Dichrocephala bicolor

    Article • Journal of Natural Products, March 1999, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  82. Effects of methanol extract of chansu on hypothalamic-pituitary-testis function in rats

    Article • Metabolism, October 1998, Elsevier

    Dr Lie-Chwen Lin

  83. Phenyl β-d-Glucopyranoside Derivatives from the Fruits of Idesia polycarpa

    Article • Journal of Natural Products, April 1997, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  84. High-performance liquid chromatographic determination of evodiamine in rat plasma: application to pharmacokinetic studies

    Article • Journal of Chromatography B Biomedical Sciences and Applications, June 1995, Elsevier

    Dr Lie-Chwen Lin

  85. 7-Hydroxyrutaecarpine from Tetradium glabrifolium and Tetradium ruticarpum

    Article • Heterocycles, January 1995, Japan Institute of Heterocyclic Chemistry

    Dr Lie-Chwen Lin

  86. Northalifoline, a New Isoquinolone Alkaloid from the Pedicels of Lindera megaphylla

    Article • Journal of Natural Products, June 1994, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  87. Toxicologic Studies of Dihydro-5,6-dehydrokawain and 5,6-Dehydrokawain

    Article • Planta Medica, February 1994, Thieme Publishing Group

    Dr Lie-Chwen Lin

  88. High-performance liquid chromatography of the quinazolinocarboline alkaloid dehydroevodiamine

    Article • Journal of Chromatography B Biomedical Sciences and Applications, July 1993, Elsevier

    Dr Lie-Chwen Lin

  89. Two New Acetophenones from Fruits of Evodia merrillii

    Article • Journal of Natural Products, June 1993, American Chemical Society (ACS)

    Dr Lie-Chwen Lin

  90. Determination of Aristolochic Acid in Rabbit Plasma by High-Performance Liquid Chromatography with Photodiode-Array Ultraviolet Detection and Its Pharmacokinetics Application

    Article • Journal of Liquid Chromatography, April 1993, Taylor & Francis

    Dr Lie-Chwen Lin

  91. Novel Acetophenones from Fruits of Evodia merrillii

    Article • Journal of Natural Products, June 1992, American Chemical Society (ACS)

    Dr Lie-Chwen Lin