Joshua Sakon

All Stories

1. 
   Alternate carbohydrate and nontraditional inducer leads to increased productivity of a collagen binding domain fusion protein via fed-batch fermentation

   Article • Journal of Biotechnology, May 2016, Elsevier

   Joshua Sakon

2. 
   Fluorescent ampicillin analogues as multifunctional disguising agents against opsonization

   Article • Nanoscale, January 2016, Royal Society of Chemistry

   Joshua Sakon

3. 
   Structures of three polycystic kidney disease-like domains fromClostridium histolyticumcollagenases ColG and ColH

   Article • Acta Crystallographica Section D Biological Crystallography, February 2015, International Union of Crystallography

   Joshua Sakon

4. 
   Expression of a collagen-binding domain fusion protein: Effect of amino acid supplementation, inducer type, and culture conditions

   Article • Biotechnology Progress, February 2015, Wiley

   Joshua Sakon

5. 
   Parathyroid hormone linked to a collagen binding domain promotes hair growth in a mouse model of chemotherapy-induced alopecia in a dose-dependent manner

   Article • Anti-Cancer Drugs, August 2014, Wolters Kluwer Health

   Joshua Sakon

6. 
   Crystal Structure of Staphylococcal Nuclease mutant V23L/L25V/V66L

   Article • June 2014, Protein Data Bank, Rutgers University

   Joshua Sakon

7. 
   Pharmacokinetics in Rats of a Long-Acting Human Parathyroid Hormone–Collagen Binding Domain Peptide Construct

   Article • Journal of Pharmaceutical Sciences, February 2014, Elsevier

   Joshua Sakon

8. 
   Treatment and prevention of chemotherapy-induced alopecia with PTH-CBD, a collagen-targeted parathyroid hormone analog, in a non-depilated mouse model

   Article • Anti-Cancer Drugs, January 2014, Wolters Kluwer Health

   Joshua Sakon

9. 
   Therapy for Alopecia Areata in Mice Using Parathyroid Hormone Agonists and Antagonists, Linked to a Collagen-Binding Domain

   Article • Journal of Investigative Dermatology Symposium Proceedings, December 2013, Elsevier

   Joshua Sakon

10. 
    Crystal Structure of Staphylococcal nuclease mutant V23L/V66I

    Article • May 2013, Protein Data Bank, Rutgers University

    Joshua Sakon

11. 
    Crystal Structure of Staphylococcal Nuclease mutant I92V/V99L

    Article • May 2013, Protein Data Bank, Rutgers University

    Joshua Sakon

12. 
    Crystal Structure of Staphylococcal nuclease mutant V66I/V99L

    Article • April 2013, Protein Data Bank, Rutgers University

    Joshua Sakon

13. 
    Crystal Structure of Staphylococcal nuclease mutant V23I/L25V/I72V/I92V

    Article • March 2013, Protein Data Bank, Rutgers University

    Joshua Sakon

14. 
    Crystal Structure of Staphylococcal nuclease mutant V23I/I72L

    Article • March 2013, Protein Data Bank, Rutgers University

    Joshua Sakon

15. 
    Structural Comparison of ColH and ColG Collagen-Binding Domains from Clostridium histolyticum

    Article • Journal of Bacteriology, November 2012, ASM Journals

    Joshua Sakon

16. 
    Crystal Structure of Staphylococcal nuclease mutant I72V/V99L

    Article • October 2012, Protein Data Bank, Rutgers University

    Joshua Sakon

17. 
    Bacterial collagen-binding domain targets undertwisted regions of collagen

    Article • Protein Science, September 2012, Wiley

    Joshua Sakon

18. 
    Staphylococcal Nuclease double mutant I72L, I92L

    Article • August 2012, Protein Data Bank, Rutgers University

    Joshua Sakon

19. 
    Treatment for chemotherapy-induced alopecia in mice using parathyroid hormone agonists and antagonists linked to a collagen binding domain

    Article • International Journal of Cancer, January 2012, Wiley

    Joshua Sakon

20. 
    The Crystal Structure of the Polycystic Kidney Disease Domain (PKD) from Clostridium Histolyticum Collagenase: Insight into the Role of the PKD in Collagenase

    Article • Biophysical Journal, January 2012, Elsevier

    Joshua Sakon

21. 
    Probing the 3-D Structure, Dynamics, and Stability of Bacterial Collagenase Collagen Binding Domain (apo- versus holo-) by Limited Proteolysis MALDI-TOF MS

    Article • Journal of the American Society for Mass Spectrometry, December 2011, Springer Science + Business Media

    Joshua Sakon

22. 
    Crystal structure of Clostridium histolyticum colG collagenase polycystic kidney disease domain at 1.4 Angstrom resolution

    Article • September 2010, Protein Data Bank, Rutgers University

    Joshua Sakon

23. 
    Aqueous-phase synthesis of monodisperse plasmonic gold nanocrystals using shortened single-walled carbon nanotubes

    Article • Chemical Communications, January 2010, Royal Society of Chemistry

    Joshua Sakon

24. 
    Characterization of the Minimalistic Fgf-D2 Domain Interface

    Article • Biophysical Journal, January 2010, Elsevier

    Joshua Sakon

25. 
    Crystal Structure of Synaptotagmin I C2A domain with Cu(II)

    Article • October 2009, Protein Data Bank, Rutgers University

    Joshua Sakon

26. 
    Crystal Structure of Synaptotagmin I C2A domain with Mn(II)

    Article • October 2009, Protein Data Bank, Rutgers University

    Joshua Sakon

27. 
    Crystal Structure of Synaptotagmin I C2A domain

    Article • September 2009, Protein Data Bank, Rutgers University

    Joshua Sakon

28. 
    Crystal Structure of Synaptotagmin I C2A domain with Cu(II)

    Article • September 2009, Protein Data Bank, Rutgers University

    Joshua Sakon

29. 
    Crystal structure of the FGFR2 D2 domain

    Article • August 2009, Protein Data Bank, Rutgers University

    Joshua Sakon

30. 
    Ca2+-induced linker transformation leads to a compact and rigid collagen-binding domain of Clostridium histolyticum collagenase

    Article • FEBS Journal, June 2009, Wiley

    Joshua Sakon

31. 
    Crystal Structure of 2:2:2 FGFR2D2:FGF1:SOS complex

    Article • April 2009, Protein Data Bank, Rutgers University

    Joshua Sakon

32. 
    Crystal Structure of hFGFR2 D2 Domain

    Article • January 2009, Protein Data Bank, Rutgers University

    Joshua Sakon

33. 
    1H, 13C and 15N resonance assignments of Ca2+ bound collagen-binding domain derived from a clostridial collagenase

    Article • Biomolecular NMR Assignments, July 2008, Springer Science + Business Media

    Joshua Sakon

34. 
    Hepatitis C Virus NS3 Helicase Forms Oligomeric Structures That Exhibit Optimal DNA Unwinding Activity in Vitro

    Article • Journal of Biological Chemistry, February 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Joshua Sakon

35. 
    Crystal structure of Staphylococcal nuclease mutant L25I

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

36. 
    Crystal structure of Staphylococcal nuclease mutant V66I

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

37. 
    Crystal structure of Staphylococcal nuclease mutant V23L/I72L

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

38. 
    Crystal structure of Staphylococcal nuclease mutant L25I/I72L

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

39. 
    Crystal structure of Staphylococcal nuclease mutant V66I/I72V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

40. 
    Crystal structure of Staphylococcal nuclease mutant V66L/V99I

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

41. 
    Crystal structure of Staphylococcal nuclease mutant I72L

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

42. 
    Crystal structure of Staphylococcal nuclease mutant T120C

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

43. 
    Crystal structure of Staphylococcal nuclease mutant T41S

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

44. 
    Crystal structure of Staphylococcal nuclease mutant T41V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

45. 
    Crystal structure of Staphylococcal nuclease mutant T22V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

46. 
    Crystal structure of Staphylococcal nuclease mutant T41C

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

47. 
    Crystal structure of Staphylococcal nuclease mutant T82S

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

48. 
    Crystal structure of Staphylococcal nuclease mutant T44V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

49. 
    Crystal structure of Staphylococcal nuclease mutant T120S

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

50. 
    Crystal structure of Staphylococcal nuclease mutant T62S

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

51. 
    Crystal structure of Staphylococcal nuclease mutant T62V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

52. 
    Crystal structure of Staphylococcal nuclease mutant T120V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

53. 
    Crystal structure of Staphylococcal nuclease mutant T22C

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

54. 
    Crystal structure of Staphylococcal nuclease mutant V23L

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

55. 
    Crystal structure of Staphylococcal nuclease mutant I92V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

56. 
    Crystal structure of Staphylococcal nuclease mutant V23L/I72V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

57. 
    Crystal structure of Staphylococcal nuclease mutant V66L

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

58. 
    Crystal structure of Staphylococcal nuclease mutant I72V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

59. 
    Crystal structure of Staphylococcal nuclease mutant V23I/L25I/I72V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

60. 
    Crystal structure of Staphylococcal nuclease mutant V23L/V66L/I72L

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

61. 
    Crystal structure of Staphylococcal nuclease mutant V23I/L25I

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

62. 
    Crystal structure of Staphylococcal nuclease mutant V66I/V99I

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

63. 
    Crystal structure of Staphylococcal nuclease mutant V66L/I92L

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

64. 
    Crystal structure of Staphylococcal nuclease mutant V66L/I92V

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

65. 
    Crystal structure of Staphylococcal nuclease mutant V23I/L25I/V66L/I72L

    Article • October 2006, Protein Data Bank, Rutgers University

    Joshua Sakon

66. 
    Two hepatitis c virus ns3 helicase domains complexed with the same strand of dna

    Article • December 2005, Protein Data Bank, Rutgers University

    Joshua Sakon

67. 
    Crystal structure of the cell wall targeting domain of peptidylglycan hydrolase ALE-1

    Article • April 2005, Protein Data Bank, Rutgers University

    Joshua Sakon

68. 
    Catalytically Enhanced Endocellulase Cel5A from Acidothermus cellulolyticus

    Article • Applied Biochemistry and Biotechnology, January 2005, Springer Science + Business Media

    Joshua Sakon

69. 
    Proteins with simplified hydrophobic cores compared to other packing mutants

    Article • Biophysical Chemistry, August 2004, Elsevier

    Joshua Sakon

70. 
    Structure of S. nuclease mutant quintuple mutant V23L/V66L/I72L/I92L/V99L

    Article • June 2003, Protein Data Bank, Rutgers University

    Joshua Sakon

71. 
    Structure of S. nuclease quintuple mutant V23I/V66L/I72L/I92L/V99L

    Article • June 2003, Protein Data Bank, Rutgers University

    Joshua Sakon

72. 
    Exploration of Cellulose Surface-Binding Properties of Acidothermus cellulolyticus Cel5A by Site-Specific Mutagenesis

    Article • January 2002, Springer Science + Business Media

    Joshua Sakon

73. 
    Exploration of Cellulose Surface-Binding Properties of Acidothermus cellulolyticus Cel5A by Site-Specific Mutagenesis

    Article • Applied Biochemistry and Biotechnology, January 2002, Springer Science + Business Media

    Joshua Sakon

74. 
    Characterization of metal affinity of green fluorescent protein and its purification through salt promoted, immobilized metal affinity chromatography

    Article • Journal of Chromatography A, February 2001, Elsevier

    Joshua Sakon

75. 
    STRUCTURE OF S. NUCLEASE STABILIZING MUTANT S59A

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

76. 
    STRUCTURE OF S. NUCLEASE STABILIZING MUTANT T33V

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

77. 
    STRUCTURE OF S. NUCLEASE STABILIZING MUTANT T41I

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

78. 
    STRUCTURE OF S. NUCLEASE STABILIZING MUTANT T33V

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

79. 
    STRUCTURE OF S. NUCLEASE STABILIZING MUTANT S128A

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

80. 
    STRUCTURE OF S. NUCLEASE STABILIZING QUADRUPLE MUTANT T41I/P117G/H124L/S128A

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

81. 
    STRUCTURE OF S. NUCLEASE STABILIZING SEXTUPLE MUTANT T33V/T41I/S59A/P117G/H124L/S128A

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

82. 
    STRUCTURE OF WILD-TYPE S. NUCLEASE AT 1.6 A RESOLUTION

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

83. 
    STRUCTURE OF S. NUCLEASE STABILIZING TRIPLE MUTANT P117G/H124L/S128A

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

84. 
    STRUCTURE OF WILD-TYPE S. NUCLEASE AT 1.7 A RESOLUTION

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

85. 
    STRUCTURE OF S. NUCLEASE STABILIZING QUINTUPLE MUTANT T33V/T41I/P117G/H124L/S128A

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

86. 
    STRUCTURE OF S. NUCLEASE STABILIZING QUINTUPLE MUTANT T41I/S59A/P117G/H124L/S128A

    Article • October 2000, Protein Data Bank, Rutgers University

    Joshua Sakon

87. 
    Ab Initio Study of the Conformational Dependence of the Nonplanarity of the Peptide Group

    Article • The Journal of Physical Chemistry A, October 2000, American Chemical Society (ACS)

    Joshua Sakon

88. 
    ENDOCELLULASE E1 FROM ACIDOTHERMUS CELLULOLYTICUS MUTANT Y245G

    Article • July 1999, Protein Data Bank, Rutgers University

    Joshua Sakon

89. 
    Structure and mechanism of endo/exocellulase E4 from Thermomonospora fusca

    Article • Nature Structural Biology, October 1997, Nature

    Joshua Sakon

90. 
    ENDO/EXOCELLULASE:CELLOBIOSE FROM THERMOMONOSPORA

    Article • September 1997, Protein Data Bank, Rutgers University

    Joshua Sakon

91. 
    ENDO/EXOCELLULASE FROM THERMOMONOSPORA

    Article • September 1997, Protein Data Bank, Rutgers University

    Joshua Sakon

92. 
    ENDO/EXOCELLULASE:CELLOTRIOSE FROM THERMOMONOSPORA

    Article • September 1997, Protein Data Bank, Rutgers University

    Joshua Sakon

93. 
    ENDO/EXOCELLULASE:CELLOPENTAOSE FROM THERMOMONOSPORA

    Article • September 1997, Protein Data Bank, Rutgers University

    Joshua Sakon

94. 
    Polysaccharide hydrolase folds diversity of structure and convergence of function

    Article • Applied Biochemistry and Biotechnology, March 1997, Springer Science + Business Media

    Joshua Sakon

95. 
    Polysaccharide Hydrolase Folds Diversity of Structure and Convergence of Function

    Article • January 1997, Springer Science + Business Media

    Joshua Sakon

96. 
    ACIDOTHERMUS CELLULOLYTICUS ENDOCELLULASE E1 CATALYTIC DOMAIN IN COMPLEX WITH A CELLOTETRAOSE

    Article • October 1996, Protein Data Bank, Rutgers University

    Joshua Sakon

97. 
    Crystal Structure of Thermostable Family 5 Endocellulase E1 fromAcidothermus cellulolyticusin Complex with Cellotetraose†,‡

    Article • Biochemistry, January 1996, American Chemical Society (ACS)

    Joshua Sakon

98. 
    Molecular structure of kanamycin nucleotidyltransferase determined to 3.0-.ANG. resolution

    Article • Biochemistry, November 1993, American Chemical Society (ACS)

    Joshua Sakon

99. 
    Crystallization and preliminary crystallographic analysis of a thermostable mutant of kanamycin nucleotidyltransferase

    Article • Archives of Biochemistry and Biophysics, May 1992, Elsevier

    Joshua Sakon

100. 
     Catalytically Enhanced Endocellulase CeI5A from Acidothermus cellulolyticus

     Article • Springer Science + Business Media

     Joshua Sakon