All Stories

  1. High-resolution crystal structures of alternate forms of the human CD44 hyaluronan-binding domain reveal a site for protein interaction

    Article • Acta Crystallographica Section F Structural Biology Communications, August 2014, International Union of Crystallography

    Professor Barry C Finzel

  2. Fragment-Based Identification of an Inducible Binding Site on Cell Surface Receptor CD44 for the Design of Protein–Carbohydrate Interaction Inhibitors

    Article • Journal of Medicinal Chemistry, March 2014, American Chemical Society (ACS)

    Professor Barry C Finzel

  3. Cover Picture: Inhibition of Mycobacterium tuberculosis Transaminase BioA by Aryl Hydrazines and Hydrazides (ChemBioChem 4/2014)

    Article • ChemBioChem, February 2014, Wiley

    Professor Barry C Finzel

  4. Inhibition of Mycobacterium tuberculosis Transaminase BioA by Aryl Hydrazines and Hydrazides

    Article • ChemBioChem, January 2014, Wiley

    Professor Barry C Finzel

  5. The structure of the TOG-like domain ofDrosophila melanogasterMast/Orbit

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, June 2013, International Union of Crystallography

    Professor Barry C Finzel

  6. Structural characterization of human histidine triad nucleotide‐binding protein 2, a member of the histidine triad superfamily

    Article • FEBS Journal, June 2013, Wiley

    Professor Barry C Finzel

  7. Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring

    Article • Bioorganic & Medicinal Chemistry Letters, May 2012, Elsevier

    Professor Barry C Finzel

  8. Use of differential scanning fluorimetry to optimize the purification and crystallization of PLP-dependent enzymes

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, April 2012, International Union of Crystallography

    Professor Barry C Finzel

  9. Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis

    Article • Chemistry & Biology, November 2011, Elsevier

    Professor Barry C Finzel

  10. Mechanism-based Inactivation by Aromatization of the Transaminase BioA Involved in Biotin Biosynthesis in Mycobaterium tuberculosis

    Article • Journal of the American Chemical Society, October 2011, American Chemical Society (ACS)

    Professor Barry C Finzel

  11. Conserved Core Substructures in the Overlay of Protein–Ligand Complexes

    Article • Journal of Chemical Information and Modeling, July 2011, American Chemical Society (ACS)

    Professor Barry C Finzel

  12. Kinetic and structural characterization of caspase-3 and caspase-8 inhibition by a novel class of irreversible inhibitors

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, September 2010, Elsevier

    Professor Barry C Finzel

  13. Identification of Novel Non-Hydroxamate Anthrax Toxin Lethal Factor Inhibitors by Topomeric Searching, Docking and Scoring, and in Vitro Screening

    Article • Journal of Chemical Information and Modeling, November 2009, American Chemical Society (ACS)

    Professor Barry C Finzel

  14. Rational protein engineering in action: The first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus

    Article • Journal of Structural Biology, April 2008, Elsevier

    Professor Barry C Finzel, Dr Artem Evdokimov

  15. N-(6,7-Dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-N-alkylsulfonamides as peripherally restricted N-methyl-d-aspartate receptor antagonists for the treatment of pain

    Article • Bioorganic & Medicinal Chemistry Letters, August 2007, Elsevier

    Professor Barry C Finzel

  16. Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid

    Article • Bioorganic & Medicinal Chemistry Letters, June 2005, Elsevier

    Professor Barry C Finzel

  17. Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid

    Article • Bioorganic & Medicinal Chemistry Letters, May 2005, Elsevier

    Professor Barry C Finzel

  18. Synthesis of a Series of Stromelysin-Selective Thiadiazole Urea Matrix Metalloproteinase Inhibitors

    Article • Journal of Medicinal Chemistry, April 1999, American Chemical Society (ACS)

    Professor Barry C Finzel, Dr Chris Fisher

  19. [12] LORE: Exploiting database of known structures

    Article • January 1997, Elsevier

    Professor Barry C Finzel