All Stories

  1. Immunostimulation mechanisms of jellyfish collagen on mouse bone marrow-derived dendritic cells

    Article • January 2023, American Institute of Physics

    Dr Kosuke Nishi

  2. Aqueous Extract from Leaves of Citrus unshiu Attenuates Lipopolysaccharide-Induced Inflammatory Responses in a Mouse Model of Systemic Inflammation

    Article • Plants, August 2021, MDPI AG

    Dr Kosuke Nishi

  3. Anti-Allergy Potential of Averrhoa bilimbi Linn. Fruit Water Extract Shown by Its Suppressive Effect on the Degranulation of RBL-2H3 Cells

    Article • Journal of Functional Food and Nutraceutical, February 2021, Academic Research and Community Service Swiss German University

    Dr Kosuke Nishi

  4. Discovery of stereospecific cytotoxicity of (8R,8′R)-trans-arctigenin against insect cells and structure-activity relationship on aromatic ring

    Article • Bioorganic & Medicinal Chemistry Letters, July 2020, Elsevier

    Dr Kosuke Nishi

  5. Anti-melanogenic activity of methanolic extract from leaves of Sorbaria sorbifolia var. stellipila Max. on α-MSH-stimulated B16 melanoma 4A5 cells

    Article • Biomedical Dermatology, April 2020, Springer Science + Business Media

    Dr Kosuke Nishi

  6. Trigonelline: An alkaloid with anti-degranulation properties

    Article • Molecular Immunology, February 2020, Elsevier

    Dr Kosuke Nishi

  7. Cytotoxicity against HL60 Cells of Ficifolidione Derivatives with Methyl, n-Pentyl, and n-Heptyl Groups

    Article • Molecules, November 2019, MDPI AG

    Dr Kosuke Nishi

  8. Docosahexaenoyl ethanolamide mitigates IgE-mediated allergic reactions by inhibiting mast cell degranulation and regulating allergy-related immune cells

    Article • Scientific Reports, November 2019, Springer Science + Business Media

    Dr Kosuke Nishi

  9. Structure–Activity Relationships of Fish Oil Derivatives with Antiallergic Activity in Vitro and in Vivo

    Article • Journal of Medicinal Chemistry, October 2019, American Chemical Society (ACS)

    Dr Kosuke Nishi

  10. Anti-degranulation activity of caffeine: In vitro and in vivo study

    Article • Journal of Functional Foods, September 2019, Elsevier

    Dr Kosuke Nishi

  11. Design of 92 New 9-Norlignan Derivatives and Their Effect on Cell Viabilities of Cancer and Insect Cells

    Article • Journal of Agricultural and Food Chemistry, June 2019, American Chemical Society (ACS)

    Dr Kosuke Nishi

  12. Anti-inflammatory effect of aqueous extract from Kawachi-bankan (Citrus maxima) peel in vitro and in vivo

    Article • Cytotechnology, June 2019, Springer Science + Business Media

    Dr Kosuke Nishi

  13. A simple and versatile authenticity assay of coffee products by single-nucleotide polymorphism genotyping

    Article • Bioscience Biotechnology and Biochemistry, May 2019, Taylor & Francis

    Dr Kosuke Nishi

  14. Inhibitory effect of aqueous extract of Cuminum cyminum L. seed on degranulation of RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice

    Article • Cytotechnology, March 2019, Springer Science + Business Media

    Dr Kosuke Nishi

  15. EEG Activity in Response to Odors Produced by Organic Compounds

    Article • Journal of Psychophysiology, February 2019, Hogrefe Publishing Group

    Kandhasamy Sowndhararajan, Dr Kosuke Nishi

  16. Lysozyme from hen egg white ameliorates lipopolysaccharide-induced systemic inflammation in mice

    Article • Cytotechnology, February 2019, Springer Science + Business Media

    Dr Kosuke Nishi

  17. A time series analysis to investigate the effect of inhalation of aldehyde C10 on the human EEG activity

    Article • European Journal of Integrative Medicine, January 2019, Elsevier

    Dr Kosuke Nishi

  18. Inhibitory effect of Japanese black vinegar on IgE-mediated degranulation of RBL-2H3 cells and a murine model of Japanese cedar pollinosis

    Article • Cytotechnology, March 2018, Springer Science + Business Media

    Dr Kosuke Nishi

  19. Anti-inflammatory effect of lysozyme from hen egg white on mouse peritoneal macrophages

    Article • Cytotechnology, March 2018, Springer Science + Business Media

    Dr Kosuke Nishi

  20. Suppressive effect of ethanol extract from mango (Mangifera indica L.) peel on IgE production in vitro and in vivo

    Article • Bioscience Biotechnology and Biochemistry, January 2018, Taylor & Francis

    Dr Kosuke Nishi

  21. Synthesis and inhibitory activity of 1,3-(adamantan-1(2)-yl)- imidazolidine-2,4,5-triones and 3,3'-(adamantan-1-yl)- bis(1-alkylimidazolidine-2,4,5-triones)

    Article • Chemistry of Heterocyclic Compounds, October 2017, Springer Science + Business Media

    Dr Kosuke Nishi

  22. Syntheses of cytotoxic novel arctigenin derivatives bearing halogen and alkyl groups on aromatic rings

    Article • Bioorganic & Medicinal Chemistry Letters, September 2017, Elsevier

    Dr Kosuke Nishi

  23. Immunomodulatory Activity of Octenyl Succinic Anhydride Modified Porang (Amorphophallus oncophyllus) Glucomannan on Mouse Macrophage-Like J774.1 Cells and Mouse Primary Peritoneal Macrophages

    Article • Molecules, July 2017, MDPI AG

    Dr Kosuke Nishi

  24. Immunostimulatory effect of aqueous extract ofCoriandrum sativumL. seed on macrophages

    Article • Journal of the Science of Food and Agriculture, May 2017, Wiley

    Dr Kosuke Nishi

  25. Suppressive effect of ethanol extract from passion fruit seeds on IgE production

    Article • Journal of Functional Foods, May 2017, Elsevier

    Dr Kosuke Nishi

  26. Immunostimulatory effect of dried bonito extract on mouse macrophage cell lines and mouse primary peritoneal macrophages

    Article • Cytotechnology, January 2017, Springer Science + Business Media

    Dr Kosuke Nishi

  27. Immunostimulatory activity of snake fruit (Salacca edulis Reinw.) cultivar Pondoh Hitam extract on the activation of macrophages in vitro

    Article • January 2017, American Institute of Physics

    Dr Kosuke Nishi

  28. Nobiletin suppresses monocyte chemoattractant protein-1 (MCP-1) expression by regulating MAPK signaling in 3T3-L1 cells

    Article • Journal of Functional Foods, December 2016, Elsevier

    Dr Kosuke Nishi

  29. Enantioselective syntheses of both enantiomers of 9′-dehydroxyimperanene and 7,8-dihydro-9′-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids

    Article • Bioorganic & Medicinal Chemistry Letters, July 2016, Elsevier

    Dr Kosuke Nishi

  30. In vivo selection of active deoxyribonucleoside kinase by a mutagenic nucleoside analog

    Article • Journal of Biotechnology, June 2016, Elsevier

    Dr Kosuke Nishi

  31. Immunostimulatory effect of spinach aqueous extract on mouse macrophage-like J774.1 cells and mouse primary peritoneal macrophages

    Article • Bioscience Biotechnology and Biochemistry, April 2016, Taylor & Francis

    Dr Kosuke Nishi

  32. Effect of concurrent administration of nobiletin and β-lactoglobulin on the symptoms of Japanese cedar pollinosis models in mice

    Article • Journal of Functional Foods, April 2016, Elsevier

    Dr Kosuke Nishi

  33. Effect of the structure of dietary epoxylignan on its cytotoxic activity: relationship between the structure and the activity of 7,7′-epoxylignan and the introduction of apoptosis by caspase 3/7

    Article • Bioscience Biotechnology and Biochemistry, January 2016, Taylor & Francis

    Dr Kosuke Nishi

  34. Inhibitory effects of enzyme-treated dried sardine extract on IgE-mediated degranulation of RBL-2H3 cells and a murine model of Japanese cedar pollinosis

    Article • RSC Advances, January 2016, Royal Society of Chemistry

    Dr Kosuke Nishi

  35. Structure–activity relationships of amide–phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase

    Article • Bioorganic & Medicinal Chemistry, November 2015, Elsevier

    Dr Kosuke Nishi

  36. Immunostimulatory activity of snake fruit peel extract on murine macrophage-like J774.1 cells

    Article • Cytotechnology, October 2015, Springer Science + Business Media

    Dr Kosuke Nishi

  37. Jellyfish collagen stimulates maturation of mouse bone marrow-derived dendritic cells

    Article • Journal of Functional Foods, April 2015, Elsevier

    Dr Kosuke Nishi

  38. Ishizuchi dark tea suppresses IgE-mediated degranulation of RBL-2H3 cells and nasal rubbing behavior of pollinosis in mice

    Article • Journal of Functional Foods, April 2015, Elsevier

    Dr Kosuke Nishi

  39. Acute Larvicidal Activity against Mosquitoes and Oxygen Consumption Inhibitory Activity of Dihydroguaiaretic Acid Derivatives

    Article • Journal of Agricultural and Food Chemistry, March 2015, American Chemical Society (ACS)

    Dr Kosuke Nishi

  40. Revised Stereochemistry of Ficifolidione and Its Biological Activities against Insects and Cells

    Article • Journal of Natural Products, January 2015, American Chemical Society (ACS)

    Dr Kosuke Nishi

  41. Methoxychlor enhances degranulation of murine mast cells by regulating FcϵRI-mediated signal transduction

    Article • Journal of Immunotoxicology, November 2014, Informa Healthcare

    Dr Kosuke Nishi

  42. The major whey protein β-lactoglobulin inhibits IgE-mediated degranulation of RBL-2H3 cells and passive cutaneous anaphylaxis in mice

    Article • International Dairy Journal, November 2014, Elsevier

    Dr Kosuke Nishi

  43. Studies on anti-allergic activity of Sargassum horneri extract

    Article • Journal of Functional Foods, September 2014, Elsevier

    Dr Kosuke Nishi

  44. Cytotoxic activity of butane type of 1,7-seco-2,7′-cyclolignanes and apoptosis induction by Caspase 9 and 3

    Article • Bioorganic & Medicinal Chemistry Letters, September 2014, Elsevier

    Dr Kosuke Nishi

  45. Cytotoxic Activity of Dietary Lignan and Its Derivatives: Structure–Cytotoxic Activity Relationship of Dihydroguaiaretic Acid

    Article • Journal of Agricultural and Food Chemistry, June 2014, American Chemical Society (ACS)

    Dr Kosuke Nishi

  46. Jellyfish collagen stimulates production of TNF-α and IL-6 by J774.1 cells through activation of NF-κB and JNK via TLR4 signaling pathway

    Article • Molecular Immunology, March 2014, Elsevier

    Dr Kosuke Nishi

  47. Structure–activity relationships of substituted oxyoxalamides as inhibitors of the human soluble epoxide hydrolase

    Article • Bioorganic & Medicinal Chemistry, February 2014, Elsevier

    Dr Kosuke Nishi

  48. Activation of macrophages stimulated by the bengkoang fiber extract through toll-like receptor 4

    Article • Food & Function, January 2014, Royal Society of Chemistry

    Dr Kosuke Nishi

  49. Nobiletin, a polymethoxy flavonoid, exerts anti-allergic effect by suppressing activation of phosphoinositide 3-kinase

    Article • Journal of Functional Foods, January 2014, Elsevier

    Dr Kosuke Nishi

  50. Activation of J774.1 murine macrophages by lactate dehydrogenase

    Article • Cytotechnology, October 2013, Springer Science + Business Media

    Dr Kosuke Nishi

  51. Structure–cytotoxic activity relationship of sesquilignan, morinol A

    Article • Bioorganic & Medicinal Chemistry Letters, September 2013, Elsevier

    Dr Kosuke Nishi

  52. Effect of bengkoang (Pachyrhizus erosus) fiber extract on murine macrophage-like J774.1 cells and mouse peritoneal macrophages

    Article • Journal of Functional Foods, April 2013, Elsevier

    Dr Kosuke Nishi

  53. Immunomodulatory activity of Bengkoang (Pachyrhizus erosus) fiber extract in vitro and in vivo

    Article • Cytotechnology, January 2013, Springer Science + Business Media

    Dr Kosuke Nishi

  54. Inhibitory effect of aqueous spinach extract on degranulation of RBL-2H3 cells

    Article • Food Chemistry, January 2013, Elsevier

    Dr Kosuke Nishi

  55. Phenylhydroquinone induces loss of thymocytes through cell cycle arrest and apoptosis elevation in p53-dependent pathway

    Article • The Journal of Toxicological Sciences, January 2013, Japanese Society of Toxicology

    Dr Kosuke Nishi

  56. Structural characterization of a modification subunit of a putative type I restriction enzyme fromVibrio vulnificusYJ016

    Article • Acta Crystallographica Section D Biological Crystallography, October 2012, International Union of Crystallography

    Dr Kosuke Nishi

  57. Immunomodulatory effects of citrus fruit auraptene in vitro and in vivo

    Article • Journal of Functional Foods, October 2012, Elsevier

    Dr Kosuke Nishi

  58. Immunomodulatory effects of lactate dehydrogenase in vitro and in vivo

    Article • Journal of Functional Foods, October 2012, Elsevier

    Dr Kosuke Nishi

  59. Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase

    Article • Bioorganic & Medicinal Chemistry Letters, September 2012, Elsevier

    Dr Kosuke Nishi

  60. Immunochromatographic assay of cadmium levels in oysters

    Article • Talanta, August 2012, Elsevier

    Dr Kosuke Nishi

  61. Immunostimulatory effect of β-cryptoxanthin in vitro and in vivo

    Article • Journal of Functional Foods, July 2012, Elsevier

    Dr Kosuke Nishi

  62. Effect of collagens from jellyfish and bovine Achilles tendon on the activity of J774.1 and mouse peritoneal macrophage cells

    Article • Journal of Functional Foods, April 2012, Elsevier

    Dr Kosuke Nishi

  63. Nobiletin suppresses adipocyte differentiation of 3T3-L1 cells by an insulin and IBMX mixture induction

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, April 2012, Elsevier

    Dr Kosuke Nishi

  64. Enzyme-Linked Immunosorbent Assay with Monoclonal and Single-Chain Variable Fragment Antibodies Selective to Coplanar Polychlorinated Biphenyls

    Article • Journal of Agricultural and Food Chemistry, February 2012, American Chemical Society (ACS)

    Dr Kosuke Nishi

  65. Immunostimulatory effects of water extract from bulbus arteriosus in tuna in vitro

    Article • Journal of Functional Foods, January 2012, Elsevier

    Dr Kosuke Nishi

  66. (−)-Secoisolariciresinol attenuates high-fat diet-induced obesity in C57BL/6 mice

    Article • Food & Function, January 2012, Royal Society of Chemistry

    Dr Kosuke Nishi

  67. Evaluation of immunostimulatory effect of the arrowroot (Maranta arundinacea. L) in vitro and in vivo

    Article • Cytotechnology, October 2011, Springer Science + Business Media

    Dr Kosuke Nishi

  68. Immunomodulatory Effect of (−)-Matairesinolin Vivoandex Vivo

    Article • Bioscience Biotechnology and Biochemistry, May 2011, Taylor & Francis

    Dr Kosuke Nishi

  69. Immunostimulation Effects of Yellowtail Heart Extractsin Vitroandin Vivo

    Article • Bioscience Biotechnology and Biochemistry, April 2011, Taylor & Francis

    Dr Kosuke Nishi

  70. Structure−Activity Relationships of Cycloalkylamide Derivatives as Inhibitors of the Soluble Epoxide Hydrolase

    Article • Journal of Medicinal Chemistry, March 2011, American Chemical Society (ACS)

    Dr Kosuke Nishi

  71. Immunostimulatoryin Vitroandin VivoEffects of a Water-Soluble Extract from Kale

    Article • Bioscience Biotechnology and Biochemistry, January 2011, Taylor & Francis

    Dr Kosuke Nishi

  72. Crystal structure of the transcriptional activator HlyU fromVibrio vulnificusCMCP6

    Article • FEBS Letters, February 2010, Wiley

    Dr Kosuke Nishi

  73. Expression of the human soluble epoxide hydrolase in Escherichia coli by auto-induction for the study of high-throughput inhibition assays

    Article • Protein Expression and Purification, January 2010, Elsevier

    Dr Kosuke Nishi

  74. Expression, crystallization and preliminary X-ray diffraction analysis of a modification subunit of a putative type I restriction enzyme fromVibrio vulnificusYJ016

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, November 2009, International Union of Crystallography

    Dr Kosuke Nishi

  75. Molecular analysis of specificity of anti-nonylphenol polyethoxylate single-chain antibody fragments by grafting and designed point mutations

    Article • Molecular Immunology, September 2009, Elsevier

    Dr Kosuke Nishi

  76. The fragment structure of a putative HsdR subunit of a type I restriction enzyme from Vibrio vulnificus YJ016: implications for DNA restriction and translocation activity

    Article • Nucleic Acids Research, July 2009, Oxford University Press (OUP)

    Dr Kosuke Nishi

  77. Salicylate–urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities

    Article • Bioorganic & Medicinal Chemistry Letters, March 2009, Elsevier

    Dr Kosuke Nishi

  78. A scFv Antibody-Based Immunoaffinity Chromatography Column for Clean-Up of Bisphenol A-Contaminated Water Samples

    Article • Journal of Agricultural and Food Chemistry, January 2009, American Chemical Society (ACS)

    Dr Kosuke Nishi

  79. Crystallization and preliminary X-ray diffraction analysis of the HsdR subunit of a putative type I restriction enzyme fromVibrio vulnificusYJ016

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, September 2008, International Union of Crystallography

    Dr Kosuke Nishi

  80. Crystal Structure of a Minimal Nitroreductase, ydjA, from Escherichia coli K12 with and without FMN Cofactor

    Article • Journal of Molecular Biology, March 2008, Elsevier

    Dr Kosuke Nishi

  81. High-resolution Structure of ybfF from Escherichia coli K12: A Unique Substrate-binding Crevice Generated by Domain Arrangement

    Article • Journal of Molecular Biology, March 2008, Elsevier

    Dr Kosuke Nishi

  82. Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH)

    Article • Bioorganic & Medicinal Chemistry, February 2008, Elsevier

    Dr Kosuke Nishi

  83. 1,3-Disubstituted Ureas Functionalized with Ether Groups are Potent Inhibitors of the Soluble Epoxide Hydrolase with Improved Pharmacokinetic Properties

    Article • Journal of Medicinal Chemistry, October 2007, American Chemical Society (ACS)

    Dr Kosuke Nishi

  84. Development of highly sensitive fluorescent assays for fatty acid amide hydrolase

    Article • Analytical Biochemistry, April 2007, Elsevier

    Dr Kosuke Nishi

  85. Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase

    Article • Bioorganic & Medicinal Chemistry, January 2007, Elsevier

    Dr Kosuke Nishi

  86. Evaluation of Chiral α-Cyanoesters as General Fluorescent Substrates for Screening Enantioselective Esterases

    Article • Journal of Agricultural and Food Chemistry, February 2006, American Chemical Society (ACS)

    Dr Kosuke Nishi

  87. Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2

    Article • Archives of Biochemistry and Biophysics, January 2006, Elsevier

    Dr Kosuke Nishi

  88. Stereoselective Hydrolysis of Pyrethroid-like Fluorescent Substrates by Human and Other Mammalian Liver Carboxylesterases

    Article • Chemical Research in Toxicology, August 2005, American Chemical Society (ACS)

    Dr Kosuke Nishi

  89. Molecular and Immunochemical Characteristics of Monoclonal and Recombinant Antibodies Selective for the Triazine Herbicide Simetryn and Application to Environmental Analysis

    Article • Journal of Agricultural and Food Chemistry, June 2005, American Chemical Society (ACS)

    Dr Kosuke Nishi

  90. Optimization of Amide-Based Inhibitors of Soluble Epoxide Hydrolase with Improved Water Solubility

    Article • Journal of Medicinal Chemistry, May 2005, American Chemical Society (ACS)

    Dr Kosuke Nishi

  91. A General Method To Select Antibody Fragments Suitable for Noncompetitive Detection of Monovalent Antigens

    Article • Analytical Chemistry, August 2003, American Chemical Society (ACS)

    Dr Kosuke Nishi

  92. Preparation and Characterization of Monoclonal and Recombinant Antibodies Specific to the Insecticide Malathion

    Article • Journal of Pesticide Science, January 2003, Pesticide Science Society of Japan

    Dr Kosuke Nishi

  93. Molecular and Immunochemical Characteristics of Monoclonal and Recombinant Antibodies Specific to Bisphenol A

    Article • Bioscience Biotechnology and Biochemistry, January 2003, Taylor & Francis

    Dr Kosuke Nishi

  94. Biomonitoring for Environmental Chemicals

    Article • Journal of Pesticide Science, January 2002, Pesticide Science Society of Japan

    Dr Kosuke Nishi