All Stories

  1. C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways

    Article • Molecular Pharmacology, May 2017, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Sudarshan Rajagopal

  2. Quantitative analysis of hyperpolarized129Xe gas transfer MRI

    Article • Medical Physics, May 2017, Wiley

    Sudarshan Rajagopal

  3. Novel approach to classifying patients with pulmonary arterial hypertension using cluster analysis

    Article • Pulmonary Circulation, May 2017, SAGE Publications

    Sudarshan Rajagopal

  4. Improving on the diagnostic characteristics of echocardiography for pulmonary hypertension

    Article • The International Journal of Cardiovascular Imaging, March 2017, Springer Science + Business Media

    Sudarshan Rajagopal

  5. Systematic errors in detecting biased agonism: Analysis of current methods and development of a new model-free approach

    Article • Scientific Reports, March 2017, Nature

    Sudarshan Rajagopal

  6. Echocardiography in the Risk Assessment of Acute Pulmonary Embolism

    Article • Seminars in Respiratory and Critical Care Medicine, February 2017, Thieme Publishing Group

    Sudarshan Rajagopal

  7. A Practical Guide to Approaching Biased Agonism at G Protein Coupled Receptors

    Article • Frontiers in Neuroscience, January 2017, Frontiers

    Sudarshan Rajagopal

  8. Plasma acylcarnitines are associated with pulmonary hypertension

    Article • Pulmonary Circulation, January 2017, SAGE Publications

    Sudarshan Rajagopal

  9. GPCR desensitization: Acute and prolonged phases

    Article • Cellular Signalling, January 2017, Elsevier

    Sudarshan Rajagopal

  10. Hemodynamic Characterization of Rodent Models of Pulmonary Arterial Hypertension

    Article • Journal of Visualized Experiments, April 2016, MyJove Corporation

    Sudarshan Rajagopal

  11. Safety and Tolerability of High-dose Inhaled Treprostinil in Pulmonary Hypertension

    Article • Journal of Cardiovascular Pharmacology, April 2016, Wolters Kluwer Health

    Sudarshan Rajagopal

  12. The β-Arrestins: Multifunctional Regulators of G Protein-coupled Receptors

    Article • Journal of Biological Chemistry, March 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Sudarshan Rajagopal

  13. Abnormalities in hyperpolarized129Xe magnetic resonance imaging and spectroscopy in two patients with pulmonary vascular disease

    Article • Pulmonary Circulation, March 2016, SAGE Publications

    Sudarshan Rajagopal

  14. Use of outcome measures in pulmonary hypertension clinical trials

    Article • American Heart Journal, September 2015, Elsevier

    Sudarshan Rajagopal

  15. The Influence of Angle of Insonation and Target Depth on Speckle-Tracking Strain

    Article • Journal of the American Society of Echocardiography, May 2015, Elsevier

    Sudarshan Rajagopal

  16. What is biased efficacy? Defining the relationship between intrinsic efficacy and free energy coupling

    Article • Trends in Pharmacological Sciences, December 2014, Elsevier

    Sudarshan Rajagopal

  17. Hemodynamic Response to Continuous Outpatient Milrinone Infusion in Advanced Heart Failure Patients with Mixed Pulmonary Hypertension

    Article • Journal of Cardiac Failure, August 2014, Elsevier

    Sudarshan Rajagopal

  18. Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry

    Article • Nature Protocols, May 2014, Nature

    Sudarshan Rajagopal

  19. Right Ventricular Mechanics Using a Novel Comprehensive Three-View Echocardiographic Strain Analysis in a Normal Population

    Article • Journal of the American Society of Echocardiography, April 2014, Elsevier

    Sudarshan Rajagopal

  20. Quantifying biased agonism: understanding the links between affinity and efficacy

    Article • Nature Reviews Drug Discovery, May 2013, Nature

    Sudarshan Rajagopal

  21. Multiple ligand-specific conformations of the β2-adrenergic receptor

    Article • Nature Methods, August 2011, Nature

    Sudarshan Rajagopal

  22. BETA-ARRESTINS REGULATE SIGNALING BY BONE MORPHOGENETIC PROTEIN TYPE II RECEPTOR IN PULMONARY ARTERIAL HYPERTENSION

    Article • Journal of the American College of Cardiology, April 2011, Elsevier

    Sudarshan Rajagopal

  23. Therapeutic potential of β-arrestin- and G protein-biased agonists

    Article • Trends in Molecular Medicine, March 2011, Elsevier

    Sudarshan Rajagopal

  24. Teaching old receptors new tricks: biasing seven-transmembrane receptors

    Article • Nature Reviews Drug Discovery, May 2010, Nature

    Sudarshan Rajagopal

  25. Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit

    Article • Protein Science, September 2007, Wiley

    Sudarshan Rajagopal

  26. Purification and Initial Characterization of a Putative Blue Light-regulated Phosphodiesterase from Escherichia coli¶

    Article • Photochemistry and Photobiology, April 2007, Wiley

    Sudarshan Rajagopal

  27. A Structural Pathway for Signaling in the E46Q Mutant of Photoactive Yellow Protein

    Article • Structure, January 2005, Elsevier

    Sudarshan Rajagopal

  28. Analytical trapping: extraction of time-independent structures from time-dependent crystallographic data

    Article • Journal of Structural Biology, September 2004, Elsevier

    Sudarshan Rajagopal

  29. Chromophore Conformation and the Evolution of Tertiary Structural Changes in Photoactive Yellow Protein

    Article • Structure, June 2004, Elsevier

    Sudarshan Rajagopal

  30. Purification and Initial Characterization of a Putative Blue Light–regulated Phosphodiesterase from Escherichia coli¶

    Article • Photochemistry and Photobiology, January 2004, Wiley

    Sudarshan Rajagopal

  31. Purification and Initial Characterization of a Putative Blue Light Regulated Phosphodiesterase from Escherichia coli

    Article • Photochemistry and Photobiology, January 2004, Wiley

    Sudarshan Rajagopal

  32. Purification and Initial Characterization of a Putative Blue Light–regulated Phosphodiesterase from Escherichia coli¶

    Article • Photochemistry and Photobiology, January 2004, Wiley

    Sudarshan Rajagopal

  33. Application of Singular Value Decomposition to the Analysis of Time-Resolved Macromolecular X-Ray Data

    Article • Biophysical Journal, March 2003, Elsevier

    Sudarshan Rajagopal

  34. The LOV Domain Family:  Photoresponsive Signaling Modules Coupled to Diverse Output Domains†

    Article • Biochemistry, January 2003, American Chemical Society (ACS)

    Sudarshan Rajagopal