All Stories

  1. Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir

    Article • Bioorganic & Medicinal Chemistry, November 2023, Elsevier

    Dr. Zlatko Janeba

  2. N2′‐Branched Acyclic Nucleoside Phosphonates Containing 9‐Deazahypoxanthine as Inhibitors of Plasmodium falciparum 6‐Oxopurine Phosphoribosyltransferase

    Article • ChemMedChem, June 2023, Wiley

    Dr. Zlatko Janeba

  3. Synthesis and anti-trypanosomal evaluation of novel N-branched acyclic nucleoside phosphonates bearing 7-aryl-7-deazapurine nucleobase

    Article • European Journal of Medicinal Chemistry, September 2022, Elsevier

    Dr. Zlatko Janeba

  4. Photoswitching of 5-phenylazopyrimidines in crystalline powders and thin films

    Article • Dyes and Pigments, March 2022, Elsevier

    Dr. Zlatko Janeba

  5. Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases

    Article • Journal of Medicinal Chemistry, February 2022, American Chemical Society (ACS)

    Dr. Zlatko Janeba

  6. C1′-Branched acyclic nucleoside phosphonates mimicking adenosine monophosphate: Potent inhibitors of Trypanosoma brucei adenine phosphoribosyltransferase

    Article • European Journal of Medicinal Chemistry, December 2021, Elsevier

    Dr. Zlatko Janeba

  7. Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties

    Article • Journal of Medicinal Chemistry, October 2021, American Chemical Society (ACS)

    Dr. Zlatko Janeba

  8. Halogen‐Dance‐Based Synthesis of Phosphonomethoxyethyl (PME) Substituted 2‐Aminothiazoles as Potent Inhibitors of Bacterial Adenylate Cyclases

    Article • ChemMedChem, October 2021, Wiley

    Dr. Zlatko Janeba

  9. Polysubstituted Pyrimidines as Potent Inhibitors of Prostaglandin E2 Production: Increasing Aqueous Solubility

    Article • ChemMedChem, June 2021, Wiley

    Dr. Zlatko Janeba

  10. Diverse synthetic approaches towards C1′-branched acyclic nucleoside phosphonates

    Article • Organic & Biomolecular Chemistry, January 2021, Royal Society of Chemistry

    Dr. Zlatko Janeba

  11. Efficient Synthesis of α-Branched Purine-Based Acyclic Nucleosides: Scopes and Limitations of the Method

    Article • Molecules, September 2020, MDPI AG

    Dr. Zlatko Janeba

  12. Development of Scalable Synthesis of 5-Butyl-4-(4-methoxyphenyl)-6-phenylpyrimidin-2-amine (WQE-134), a Dual Inhibitor of Nitric Oxide and Prostaglandin E2 Production

    Article • Organic Process Research & Development, August 2020, American Chemical Society (ACS)

    Dr. Zlatko Janeba

  13. Polysubstituted Pyrimidines as mPGES‐1 Inhibitors: Discovery of Potent Inhibitors of PGE2 Production with Strong Anti‐inflammatory Effects in Carrageenan‐Induced Rat Paw Edema

    Article • ChemMedChem, August 2020, Wiley

    Dr. Zlatko Janeba

  14. Back Cover: Polysubstituted 5‐Phenylazopyrimidines: Extremely Fast Non‐ionic Photochromic Oscillators (Angew. Chem. Int. Ed. 36/2020)

    Article • Angewandte Chemie International Edition, July 2020, Wiley

    Dr. Zlatko Janeba

  15. Polysubstituted 5‐Phenylazopyrimidines: Extremely Fast Non‐ionic Photochromic Oscillators

    Article • Angewandte Chemie International Edition, July 2020, Wiley

    Dr. Zlatko Janeba

  16. Polysubstituted 5‐Phenylazopyrimidines: Extremely Fast Non‐ionic Photochromic Oscillators

    Article • Angewandte Chemie, July 2020, Wiley

    Dr. Zlatko Janeba

  17. Rücktitelbild: Polysubstituted 5‐Phenylazopyrimidines: Extremely Fast Non‐ionic Photochromic Oscillators (Angew. Chem. 36/2020)

    Article • Angewandte Chemie, July 2020, Wiley

    Dr. Zlatko Janeba

  18. Polysubstituted Pyrimidines as mPGES‐1 Inhibitors: Discovery of Potent Inhibitors of PGE2 Production with Strong Anti‐inflammatory Effects in Carrageenan‐Induced Rat Paw Edema

    Article • ChemMedChem, June 2020, Wiley

    Dr. Zlatko Janeba

  19. Synthesis of Tetrasubstituted Thiophenes via Direct Metalation

    Article • The Journal of Organic Chemistry, December 2019, American Chemical Society (ACS)

    Dr. Zlatko Janeba

  20. Sulfide, sulfoxide and sulfone bridged acyclic nucleoside phosphonates as inhibitors of the Plasmodium falciparum and human 6-oxopurine phosphoribosyltransferases: Synthesis and evaluation

    Article • European Journal of Medicinal Chemistry, December 2019, Elsevier

    Dr. Zlatko Janeba

  21. Synthesis and anti-human immunodeficiency virus activity of substituted (o,o-difluorophenyl)-linked-pyrimidines as potent non‐nucleoside reverse transcriptase inhibitors

    Article • Antiviral Chemistry and Chemotherapy, January 2019, SAGE Publications

    Dr. Zlatko Janeba

  22. Reactive cyclic intermediates in the ProTide prodrugs activation: trapping the elusive pentavalent phosphorane

    Article • Organic & Biomolecular Chemistry, January 2019, Royal Society of Chemistry

    Dr. Zlatko Janeba

  23. Meeting report: 31st International Conference on Antiviral Research

    Article • Antiviral Research, October 2018, Elsevier

    Dr. Zlatko Janeba

  24. Acyclic Nucleoside Phosphonates Bearing (R)‐ or (S)‐9‐[3‐Hydroxy‐2‐(phosphonoethoxy)propyl] (HPEP) Moiety as Monomers for the Synthesis of Modified Oligonucleotides

    Article • European Journal of Organic Chemistry, August 2018, Wiley

    Dr. Zlatko Janeba

  25. Influence of the C-5 substitution in polysubstituted pyrimidines on inhibition of prostaglandin E2 production

    Article • European Journal of Medicinal Chemistry, August 2018, Elsevier

    Dr. Zlatko Janeba

  26. Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis

    Article • ChemMedChem, July 2018, Wiley

    Dr. Zlatko Janeba

  27. Photoswitching Behavior of 5-Phenylazopyrimidines: In Situ Irradiation NMR and Optical Spectroscopy Combined with Theoretical Methods

    Article • The Journal of Organic Chemistry, April 2018, American Chemical Society (ACS)

    Dr. Zlatko Janeba

  28. Synthesis of α‐Branched Acyclic Nucleoside Phosphonates as Potential Inhibitors of Bacterial Adenylate Cyclases

    Article • ChemMedChem, January 2018, Wiley

    Dr. Zlatko Janeba

  29. Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus

    Article • Antiviral Chemistry and Chemotherapy, January 2018, SAGE Publications

    Dr. Zlatko Janeba

  30. Highlights of the 30th International Conference on Antiviral Research

    Article • Antiviral Research, September 2017, Elsevier

    Dr. Zlatko Janeba

  31. Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs

    Article • Bioorganic & Medicinal Chemistry, August 2017, Elsevier

    Dr. Zlatko Janeba

  32. Acyclic Nucleoside Phosphonates Containing 9‐Deazahypoxanthine and a Five‐Membered Heterocycle as Selective Inhibitors of Plasmodial 6‐Oxopurine Phosphoribosyltransferases

    Article • ChemMedChem, July 2017, Wiley

    Dr. Zlatko Janeba

  33. Polysubstituted 4,6-bis(hetero)arylpyrimidines as dual inhibitors of nitric oxide and prostaglandin E 2 production

    Article • Nitric Oxide, July 2017, Elsevier

    Dr. Zlatko Janeba

  34. Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases

    Article • ChemMedChem, October 2016, Wiley

    Dr. Zlatko Janeba

  35. Novel (2,6-difluorophenyl)(2-(phenylamino)pyrimidin-4-yl)methanones with restricted conformation as potent non-nucleoside reverse transcriptase inhibitors against HIV-1

    Article • European Journal of Medicinal Chemistry, October 2016, Elsevier

    Dr. Zlatko Janeba

  36. A Complete Degradation of Organophosphates by Microwave-Assisted Hydrolysis

    Article • Current Microwave Chemistry, July 2016, Bentham Science Publishers

    Dr. Zlatko Janeba

  37. Synthesis and biological properties of prodrugs of ( S )-3-(adenin-9-yl)-2-(phosphonomethoxy)propanoic acid

    Article • European Journal of Medicinal Chemistry, January 2016, Elsevier

    Dr. Zlatko Janeba

  38. Amidate Prodrugs of 9-[2-(Phosphonomethoxy)Ethyl]Adenine as Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis

    Article • Antimicrobial Agents and Chemotherapy, October 2013, ASM Journals

    Dr. Zlatko Janeba