All Stories

  1. Rottlerin suppresses growth of human pancreatic tumors in nude mice, and pancreatic cancer cells isolated from KrasG12D mice
  2. STAT3 as an emerging molecular target in pancreatic cancer
  3. Embelin Suppresses Growth of Human Pancreatic Cancer Xenografts, and Pancreatic Cancer Cells Isolated from KrasG12D Mice by Inhibiting Akt and Sonic Hedgehog Pathways
  4. Lost in Translation
  5. Clinical Implications of miRNAs in Human Diseases
  6. Challenges in Stem Cells and Translational Research
  7. Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway
  8. Rottlerin-induced autophagy leads to the apoptosis in breast cancer stem cells: molecular mechanisms
  9. Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice
  10. Epigenetic modifications by dietary phytochemicals: Implications for personalized nutrition
  11. GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft
  12. Evaluating the Effect of Therapeutic Stem Cells on TRAIL Resistant and Sensitive Medulloblastomas
  13. Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog–GLI pathway
  14. Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells
  15. Sonic Hedgehog Signaling Inhibition Provides Opportunities for Targeted Therapy by Sulforaphane in Regulating Pancreatic Cancer Stem Cell Self-Renewal
  16. EGCG Enhances the Therapeutic Potential of Gemcitabine and CP690550 by Inhibiting STAT3 Signaling Pathway in Human Pancreatic Cancer
  17. Stem Cells and Human Diseases
  18. Nutrition, Diet and Cancer
  19. Curcumin: Structure, Biology and Clinical Applications
  20. STAT Signaling in Cancer Prevention
  21. Plant Polyphenols and Their Role in Cancer Prevention and Chemotherapy
  22. Intracellular Signaling Network as a Prime Chemotherapy Target of Green Tea Catechin, (–)-Epigallocatechin-3-gallate
  23. Cancer Stem Cells: Biology, Perspectives and Therapeutic Implications
  24. Cross Talks Among Notch, Wnt, and Hedgehog Signaling Pathways Regulate Stem Cell Characteristics
  25. Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications
  26. Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular Mechanisms
  27. Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors
  28. Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics
  29. Resveratrol Inhibits Pancreatic Cancer Stem Cell Characteristics in Human and KrasG12D Transgenic Mice by Inhibiting Pluripotency Maintaining Factors and Epithelial-Mesenchymal Transition
  30. Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells
  31. Resveratrol Enhances Antitumor Activity of TRAIL in Prostate Cancer Xenografts through Activation of FOXO Transcription Factor
  32. Resveratrol Induces Growth Arrest and Apoptosis through Activation of FOXO Transcription Factors in Prostate Cancer Cells
  33. Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer
  34. FOXO transcription factors and VEGF neutralizing antibody enhance antiangiogenic effects of resveratrol
  35. Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells
  36. Inhibition of PI3K/AKT and MEK/ERK pathways act synergistically to enhance antiangiogenic effects of EGCG through activation of FOXO transcription factor
  37. Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis
  38. Histone Deacetylase Inhibitors: Mechanisms and Clinical Significance in Cancer: HDAC Inhibitor-Induced Apoptosis
  39. Linkage of Curcumin-Induced Cell Cycle Arrest and Apoptosis by Cyclin-Dependent Kinase Inhibitor p21/WAF1/CIP1
  40. Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells
  41. Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer
  42. Apoptosis, Cell Signaling, and Human Diseases
  43. Apoptosis, Cell Signaling, and Human Diseases
  44. Flavopiridol synergizes TRAIL cytotoxicity by downregulation of FLIPL
  45. Trichostatin A sensitizes TRAIL-resistant myeloma cells by downregulation of the antiapoptotic Bcl-2 proteins
  46. Interactive effects of histone deacetylase inhibitors and TRAIL on apoptosis in human leukemia cells: Involvement of both death receptor and mitochondrial pathways
  47. Interactive Effects of HDAC Inhibitors and TRAIL on Apoptosis Are Associated with Changes in Mitochondrial Functions and Expressions of Cell Cycle Regulatory Genes in Multiple Myeloma
  48. HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma
  49. Augmentation of Fas ligand-induced apoptosis by MUC1 mucin
  50. Ionizing radiation enhances the therapeutic potential of TRAIL in prostate cancer in vitro and in vivo: Intracellular mechanisms
  51. The sequential treatment with ionizing radiation followed by TRAIL/Apo-2L reduces tumor growth and induces apoptosis of breast tumor xenografts in nude mice
  52. Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications
  53. Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivo
  54. Effectiveness of the Clinical Pathway in the Management of Congestive Heart Failure
  55. Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer
  56. Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways
  57. TRAIL/Apo-2L: Mechanisms and Clinical Applications in Cancer
  58. Cytoskeletal involvement in apoptosis
  59. Intracellular Mechanisms of TRAIL and Its Role in Cancer Therapy
  60. Synergistic effects of retinoic acid and 8-Cl-cAMP on apoptosis require caspase-3 activation in human ovarian cancer cells
  61. Antisense depletion of RIα subunit of protein kinase A induces apoptosis and growth arrest in human breast cancer cells
  62. Antisense—Protein Kinase A: A Single-Gene-Based Therapeutic Approach
  63. Multifactorial Regulation of DNA Synthesis in Goldfish Ovarian Follicles
  64. Changes in the amino acid pool during embryonic development of cultured and wild Atlantic salmon (Salmo salar)
  65. Regulation of DNA synthesis in goldfish vitellogenic ovarian follicles by hormones and growth factors
  66. Effects of Activators of Different Intracellular Signaling Pathways on Steroid Production by Goldfish Vitellogenic Ovarian Follicles
  67. Assessment of egg quality in Atlantic salmon, Salmo salar, treated with testosterone: biochemical composition
  68. Changes in polyamines during embryonic development of Atlantic salmon, Salmo salar
  69. The biochemical characteristics and hatching performance of cultured and wild Atlantic salmon (Salmo salar) eggs
  70. The influence of wave frequency and wave height on the behaviour of rainbow trout (Oncorhynchus mykiss) in cages
  71. Death Receptors
  72. Regulation of NF-κB Function
  73. Clinical Significance of Histone Deacetylase Inhibitors in Cancer